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Matches 101 - 150 out of 831

Document Document Title
WO/2003/099273A1
This invention relates to a new pharmaceutically useful compound which is a stoichiometrically 1:1 adduct of tramadol hydrochloride and topiramate, and to the manufacture and use thereof.  
WO/2003/097656A2
The present invention is directed to novel compounds of the formula (I) wherein X, R1, R2 , R3, R4, R5 and R6 are as described in the specification, processes for the preparation of and pharmaceutical compositions comprising said derivat...  
WO/2003/087118A2
The invention relates to a novel method, essentially having four stages, for producing beta-L-2'-deoxy-thymidine with L-arabinose as the starting material. The inventive method is particularly useful for the large-scale production of bet...  
WO/2003/082846A1
A compound of formula (I), wherein, n is 0 or 1; R6 and R7 are h ydrogen, or together form a carbonyl oxygen; R1 is selected from the group consisting of hydrogen; -N(Z)Y and -C(Z)Y wherein; When R1 is -N(Z)Y, then: Y is selected from hy...  
WO/2003/072587A1
A novel process for producing a nonvolatile thiazolidine compound, characterized by holding a reducing sugar together with cysteine or/and cysteinyl-glycine or cystine in an aqueous medium with heating. By the process, a nonvolatile thia...  
WO/2003/041697A1
The present invention is directed to a method for treating autoimmune diseases comprising administering a therapeutically effective amount of a compound of the following formula (I) wherein X, R¿1?, R¿2?, R¿3?, R¿4?, R¿5? and R¿6? ...  
WO/2003/032905A2
Novel carbohydrate-based compounds with an attached ring system that have antimicrobial or cytostatic activity. The compounds are administered to humans and animals for the treatment or amelioration of bacterial, fungal, viral or protozo...  
WO2002003984A3
Anticonvulsant derivatives of formula (I) useful for preventing the development of Type II diabetes mellitus and Syndrome X are disclosed. Wherein X is CH 2 or oxygen; R<1> is hydrogen or alkyl; and R<2>, R<3>, R<4> and R<5> are independ...  
WO/2003/004508A1
A process for production of saccharide oxazoline derivatives represented by the general formula (2), characterized by reacting an acylamino sugar represented by the general formula (1) with a metal fluoride: (1) (2) wherein X is F, Cl, B...  
WO/2003/000200A2
The present invention includes compounds and compositions of $g(b)-halonucleosides, as well as methods to treat HIV, HBV or abnormal cellular proliferation comprising administering said compounds or compositions.  
WO/2002/098892A1
The present invention provides a novel strategy for the synthesis of allofuranose using glucofuranose as starting material in a one-pot reaction. The novel finding is that it is possible to carry out the oxidation of 1,2: 5,6-di-O-isopro...  
WO/2002/096921A1
A novel glucose derivative inducing apoptosis. The glucose derivative is represented by the following general formula (I) wherein X, Y and Z are the same or different and each is hydrogen, halogenoalkyl, hydroxy, or alkoxy, provided that...  
WO2002069704A3
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containinga) a termiticide selected such that the termiticide causes death to about 5...  
WO2002030941A3
The present invention relates to novel N12, N13-bridged sugar derivatives of indolylopyrrolocarbazoles and pharmaceutical formulations thereof which exhibit topoisomerase-I activity and are useful in inhibiting the proliferation of tumor...  
WO2002046507A3
A chemically amplified photoresist composition comprising, (a) a compound which cures upon the action of an acid or a compound whose solubility is increased upon the action of an acid; and (b) as photosensitive acid donor, at least one c...  
WO/2002/069704A2
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containinga) a termiticide selected such that the termiticide causes death to about 5...  
WO/2002/068436A1
The invention relates to avilamycin derivatives, genetic engineering, biosynthetic methods for the production thereof, medicaments containing said compounds and the utilization of said compounds for the production of a medicament against...  
WO2002032915B1
The present invention provides a monosaccharide compound of general formula I as shown in the specification. The invention also provides processes for the preparation of the compound of formula I and methods of screening for antibacteria...  
WO/2002/059131A1
The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositi...  
WO/2002/059130A1
The present invention provides stable compounds prepared from boronic acid and lyophilized compounds thereof of formula (1) in which Z?1¿ and Z?2¿ are moieties derived from sugar. The invention also provides methods for preparing such ...  
WO/2002/046507A2
A chemically amplified photoresist composition comprising, (a) a compound which cures upon the action of an acid or a compound whose solubility is increased upon the action of an acid; and (b) as photosensitive acid donor, at least one c...  
WO/2002/044194A1
A novel process for preparing 2,2'-anhydro-1-(ß-L- arabinofuranosyl)thymine which is novel and a useful intermediate; a novel process for preparing L-thymidine from 2,2'-anhydro-1-(ß-L-arabinofuranosyl)thymine; and a novel process for ...  
WO/2002/032915A1
The present invention provides a monosaccharide compound of general formula I as shown in the specification. The invention also provides processes for the preparation of the compound of formula I and methods of screening for antibacteria...  
WO/2002/030941A2
The present invention relates to novel N12, N13-bridged sugar derivatives of indolylopyrrolocarbazoles and pharmaceutical formulations thereof which exhibit topoisomerase-I activity and are useful in inhibiting the proliferation of tumor...  
WO/2002/006296A1
2,2'-Anhydronucleic acid compound derivatives useful as intermediates of drugs or agricultural chemicals or the like can be prepared from inexpensive starting compounds by reacting a compound of the general formula (2) with a compound of...  
WO/2002/003984A2
Anticonvulsant derivatives of formula (I) useful for preventing the development of Type II diabetes mellitus and Syndrome X are disclosed. Wherein X is CH ¿2? or oxygen; R?1¿ is hydrogen or alkyl; and R?2¿, R?3¿, R?4¿ and R?5¿ are ...  
WO2001014339A3
Heterocyclic aromatic amides (HAA) according to Formula (I) wherein X1-X4, M, Z, and A are herein defined. The invention also encompasses hydrates, salts and complexes thereof. These compounds are useful as antifungal agents.  
WO2000076996A3
The invention relates to a method for the enantiomer separation of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane (also described below as cis-6-benzyl-5,7-dioxooctahydropyrrolo[3,4-b]pyridine or dioxopyrrolopiperidine). The invent...  
WO/2001/023397A1
This invention relates to a method for the preparation of the phytoalexin elicitor hexasaccharide that can be used as pesticide. 1,2:5,6-Di-O-isopropylidene-glucoturanose is used as the glycosyl acceptor and 1,3-$g(b)-linked disaccharide...  
WO/2001/014339A2
Heterocyclic aromatic amides (HAA) according to Formula (I) wherein X¿1?-X¿4?, M, Z, and A are herein defined. The invention also encompasses hydrates, salts and complexes thereof. These compounds are useful as antifungal agents.  
WO/2001/007453A1
Anticonvulsant compounds of general formula (I) where X, R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, and R¿6? are as herein defined; are useful in treating acute ischemia-induced neurodegeneration, such as occurs during and after stroke, head tr...  
WO2000066604A3
Nucleoside analogues wherein a 2'-4'-bridge locks the conformation of the nucleoside have been synthesised with an inverted stereochemistry at C-3' and C-4' to provide the L-ribo-configurated LNA nucleoside. The synthesis of L-ribo-LNA-n...  
WO/2001/002412A1
The present invention relates to derivatives of 5-nitrofurfural which are useful as anticancer agents, antiviral agents, immunoprotentiators and/or as agents which may be used for combating illnesses which arise due to an elevated cell p...  
WO/2000/076996A2
The invention relates to a method for the enantiomer separation of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane (also described below as cis-6-benzyl-5,7-dioxooctahydropyrrolo[3,4-b]pyridine or dioxopyrrolopiperidine). The invent...  
WO2000042996A3
The use of anticonvulsant derivatives of formula (I) treating cluster headaches is disclosed. Wherein X is CH2 or oxygen; R1 is hydrogen of C1-C4 alkyl; and R2, R3, R4 and R5 are independently hydrogen or C1-C3 alkyl and, when X is CH2, ...  
WO/2000/068238A1
Synthetic methods for convenient large scale preparation of D-erythro sphingosines and ceramides of high isomeric purity are described.  
WO/2000/066604A2
Nucleoside analogues wherein a 2'-4'-bridge locks the conformation of the nucleoside have been synthesised with an inverted stereochemistry at C-3' and C-4' to provide the L-ribo-configurated LNA nucleoside. The synthesis of L-ribo-LNA-n...  
WO/2000/061140A1
Use of anticonvulsant derivatives of formula I for maintaining weight loss wherein X is CH¿2? or oxygen; R¿1? is hydrogen or alkyl; and R¿2?, R¿3?, R¿4? and R¿5? are independently hydrogen or alkyl and, when X is CH¿2?, R¿4? and ...  
WO/2000/061136A1
Use of anticonvulsant derivatives of formula (I) for lowering blood pressure particularly in overweight individuals, wherein X is CH¿2? or oxygen; R¿1? is hydrogen or alkyl; and R¿2?, R¿3?, R¿4? and R¿5? are independently hydrogen ...  
WO/2000/056734A1
The invention relates to compounds of formula (I), their tautomers, their salts and their water addition products, the radicals and symbols A, D, E, G and L having the meanings given in claim no. 1 and for example A = N, CR; D = C or N, ...  
WO/2000/048610A1
The present invention relates to benzaldehyde derivatives which are useful as anticancer agents. Some of the compounds of this invention are novel $i(per se).  
WO/2000/048609A1
The present invention relates to benzaldehyde derivatives which are useful as anticancer agents, antiviral agents, antibacterial agents, immunopotentiators and/or as agents which may be used for combating illnesses which arise due to an ...  
WO/2000/045812A1
Anticonvulsant derivatives useful in treating autism.  
WO2000029418A3
Inhibitors of glycosidases and glycosyltransferases, methods for their preparation and their identification are described.  
WO/2000/042996A2
The use of anticonvulsant derivatives of formula (I) treating cluster headaches is disclosed. Wherein X is CH¿2? or oxygen; R¿1? is hydrogen of C¿1?-C¿4? alkyl; and R¿2?, R¿3?, R¿4? and R¿5? are independently hydrogen or C¿1?-C...  
WO/2000/042053A1
The present application relates to a group of novel substituted pentose and hexose monosaccharide derivatives, not previously disclosed, which exhibit potent anti-cell adhesion and anti-inflammatory activities. Methods of preparation, ph...  
WO/2000/042054A1
This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O- isopropylidene-$g(a) -L-xylo-2- hexulofuranosonic acid, of formula (I) compounds of this invention are useful, inter-alia, for the inhibit...  
WO/2000/039141A1
The application relates to the design and synthesis of novel hexasaccharides of general formula (I), wherein: each R is independently selected from hydrogen, an alkyl or substituted alkyl group, an acyl or substituted acyl group, a phosp...  
WO/2000/039144A1
A process for efficiently preparing nucleoside or sugar derivatives whose secondary hydroxyl groups are selectively replaced by fluorine atoms, which comprises reacting a nucleoside or sugar derivative bearing secondary hydroxyl groups w...  
WO/2000/029418A2
Inhibitors of glycosidases and glycosyltransferases, methods for their preparation and their identification are described.  

Matches 101 - 150 out of 831