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Matches 151 - 200 out of 829

Document Document Title
WO1999064430A3
The invention provides a novel method for synthesising M6G, and intermediates therefor. In order to synthesise M6G the major problem to overcome is to obtain the glycoside linkage with very high beta -selectivity since prior methods prod...  
WO/2000/000499A1
Methods and intermediates for the preparation of oligomers containing diastereomerically enriched phosphorothioate and boranophosphate linkages are disclosed.  
WO/1999/064430A2
The invention provides a novel method for synthesising M6G, and intermediates therefor. In order to synthesise M6G the major problem to overcome is to obtain the glycoside linkage with very high $g(b)-selectivity since prior methods prod...  
WO/1999/052886A1
A method for kinetically resolving a stereoisomer mixture of compounds using asymmetric epoxidation is provided. Compounds contain an olefin moiety providing one stereoisomer to be epoxidized at a higher rate than the other stereoisomer ...  
WO/1999/047522A1
Novel granulatimide compounds and pharmaceutical formulations thereof are provided. Compounds of this invention have general formula (I) or (II) wherein are independently R or Z as defined below, or in combination F and F' is Ar¿1? as d...  
WO/1999/043667A1
The present invention relates to novel cyclic pro-perfumes having general formula (I), wherein -OR is a moiety derived from a fragrance raw material alcohol, preferably a tertiary alcohol. The cyclic pro-perfumes of the present invention...  
WO1997018222A9
Disclosed are novel oligosaccharide glycosides having mammalian immunosuppressive and tolerogenic properties, pharmaceutical compositions containing such oligosaccharide glycosides and methods of using such oligosaccharide glycosides to ...  
WO1999000399A9
C-nucleosides are synthesized by a method in which a sugar is derivatized in a single step to provide a heterocycle at the C1 position, and then the heterocycle is aromatized in another single step. In one class of preferred embodiments ...  
WO/1999/005158A1
The present invention relates to a novel and improved process for preparing 2'-fluoro-5-methyl-$g(b)-L-arabinofuranosyluridine represented by formula (1) which shows anti-viral activity, especially potent anti-viral activity against hepa...  
WO/1999/005157A1
The present invention relates to a novel and improved process for preparing 2'-fluoro-5-methyl-$g(b)-L-arabinofuranosyluridine represented by formula (1) which shows anti-viral activity, especially potent anti-viral activity against hepa...  
WO/1999/000399A1
C-nucleosides are synthesized by a method in which a sugar is derivatized in a single step to provide a heterocycle at the C¿1? position, and then the heterocycle is aromatized in another single step. In one class of preferred embodimen...  
WO/1998/030572A1
Disclosed are novel synthetic processes for the preparation of the trisaccharide $g(a)Gal(1$m(7)4)$g(b)Gal(1$m(7)4)Glc-OR compounds.  
WO1997018222A3  
WO/1998/015270A1
The present invention describes a method for treating neuropathic pain comprising administering to a mammal afflicted with such condition a therapeutically effective amount for treating such condition of a compound of formula (I), wherei...  
WO/1998/015544A1
A compound and method for producing an enantiomerically enriched epoxide from an olefin using a chiral ketone and an oxidizing agent is disclosed.  
WO/1998/007653A1
Novel chiral boron and aluminum hydride complexes, compositions comprising the chiral hydride complexes, and methods for their synthesis and use are described. The novel chiral hydride complexes are of the formulas: MBH�4-n-a?(R*)�n?...  
WO1998000130A3
Anticonvulsant derivatives useful in treating obesity are disclosed. 00000  
WO1998000129A3
Anticonvulsant derivatives useful in treating psoriasis are disclosed. 00000  
WO/1998/000129A2
Anticonvulsant derivatives useful in treating psoriasis are disclosed.  
WO/1998/000131A1
Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) are disclosed.  
WO/1998/000130A2
Anticonvulsant derivatives useful in treating obesity are disclosed.  
WO/1997/043295A1
D-Pentofuranose derivatives represented by general formulae (1) to (4) and a process for the preparation of compounds of general formula (2) by oxidizing compounds of general formula (1) with a hypochlorite in the presence of a catalytic...  
WO/1997/027205A1
This invention pertains to nucleoside analogs which have antiviral activity and improved metabolic stability, compositions comprising them, and methods of antiviral treatment employing them. More particularly, this invention pertains to ...  
WO/1997/027204A1
This invention pertains to nucleoside analogs which have antiviral activity and improved metabolic stability. More specifically, this invention pertains to modified sugar benzimidazole nucleosides, as exemplified by compounds such as ben...  
WO/1997/023494A1
Methods and compositions are provided which increase the cellular uptake of bioactive materials by covalently bonding such compounds to carbohydrate moieties through chemical linkers using other than glycosidic bonds. Numerous carbohydra...  
WO/1997/019950A1
The present invention provides a topiramate immunoassay and reagents for use in the immunoassay. In particular, topiramate is derivatized at the sulfamate moiety or the 9-carbon or 10-carbon methyl group of topiramate to add a label boun...  
WO/1997/018223A1
The present invention relates to compositions and methods for inhibiting the aging of amino-containing amino acid, peptides, proteins and biomolecules. Accordingly, a composition is disclosed which comprises an agent or compound capable ...  
WO/1997/018222A2
Disclosed are novel oligosaccharide glycosides having mammalian immunosuppressive and tolerogenic properties, pharmaceutical compositions containing such oligosaccharide glycosides and methods of using such oligosaccharide glycosides to ...  
WO/1997/017071A1
The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates.  
WO/1997/014710A1
Methods and intermediates for the preparation of oligomers containing diastereomerically enriched phosphorothioate linkages are disclosed.  
WO1997001343A3  
WO/1997/002034A1
The invention pertains to medicine and biologically active substances. The objective is to produce a drug with enhanced therapeutic effects and a broad spectrum of therapeutic properties and suitable for use in the production of highly s...  
WO/1997/001343A2
The present invention relates to a new utilization of a sophorolipidic compound, pharmaceutically acceptable salts of the acid form of the sophorolipid and of the ester of the deacetelated sophorolipid acid form as therapeutically active...  
WO/1996/039444A1
Inulins are pyrolyzed to di-D-fructose dianhydrides in good yield by heating at atmospheric pressure to a temperature sufficiently high to melt the inulin, or pyrolyzing in the presence of a hydroxy carboxylic acid such as citric acid, t...  
WO/1996/031515A1
Esters of hydroxyl-containing indolocarbazoles and acids containing selected solubilizing groups are provided. Compositions including the indolocarbazole esters and methods for the use of the indolocarbazole esters are also provided.  
WO1995029927A3  
WO/1996/008503A1
A compound of formula (I) or salts thereof, where Ro is hydrogen or together with R7O denotes a C1-C15 hydrocarbylidenedioxy group, R1 is hydrogen, R1a or a group of formula (II), R1a is R1b or a protecting group Q, R1b is C1-C20 alkyl, ...  
WO/1996/005900A1
The proposed vacuum distillation process involves dividing the liquid product fed into a vessel under a vacuum into a steam/gas phase and at least one liquid fraction, removal of the steam/gas phase from the vessel using a vacuum-produci...  
WO/1995/035102A1
2'-modified pyrimidines are prepared by a novel intramolecular nucleophilic substitution reaction.  
WO/1995/032976A1
Staurosporin derivatives of formula (I), wherein R1 is formyl, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is unsubstituted or substituted by aryl, or is an aryl radical, R2 is an aliphatic, carbocyclic, carbocycli...  
WO/1995/032974A1
The utility of known and novel staurosporin derivatives of formula (I), wherein R1 is formyl, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is unsubstituted or substituted by aryl, or is an aryl radical; R2 is hydrog...  
WO/1995/032975A1
Staurosporin derivatives of formula (I), wherein R1 is an acyl radical having from 2 to 30 carbon atoms, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is substituted by acyclic substituents, a cycloaliphatic or cyclo...  
WO/1995/029927A2
Glycoconjugate antigens are prepared by preparing a hapten glycoside, especially an alpha glycoside prepared by the Fischer method, with an olefinic aglycon moiety, especially one having a non-terminal double bond, ozonolyzing the hapten...  
WO/1995/015969A1
The present invention consists in methods of preparing sugar derivatives either in isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and ...  
WO/1995/007700A1
A method for protecting against mutational damage in mammalian cells induced by irradiation comprising administering a phosphorothioate or phosphorothioate metabolite to the mammal before or up to 3 hours after irradiation.  
WO/1994/021654A1
A process is disclosed for preparing sugar acetals by reacting sugars with ketones in the presence of an acid catalyst. By using an oxonium tetrafluoroborate as acid catalyst, yield and reaction times can be surprisingly improved.  
WO/1994/014827A1
Sulfamate derivatives having formula (I), wherein R1, R2, R3, R4, R5 and R6 are as herein defined, have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, the prese...  
WO/1994/013685A1
D-psicofuranose and D-psicopyranose derivatives represented by general formulae (I) and (II), useful as the key intermediates in a novel process for producing hydantocidin; wherein R1 through R8 may be the same or different from one anot...  
WO1994004541A3  
WO/1994/011381A1
Compounds of this invention are derivatives of pentose monosaccharides which exhibit anti-proliferative and anti-inflammatory activity as well as intermediates for the synthesis of these compounds. Methods of preparation, pharmaceutical ...  

Matches 151 - 200 out of 829