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Matches 201 - 250 out of 848

Document Document Title
WO/1994/013685A1
D-psicofuranose and D-psicopyranose derivatives represented by general formulae (I) and (II), useful as the key intermediates in a novel process for producing hydantocidin; wherein R1 through R8 may be the same or different from one anot...  
WO1994004541A3  
WO/1994/011381A1
Compounds of this invention are derivatives of pentose monosaccharides which exhibit anti-proliferative and anti-inflammatory activity as well as intermediates for the synthesis of these compounds. Methods of preparation, pharmaceutical ...  
WO/1994/006799A1
A thrombocytopenia remedy containing an indolocarbazole derivative represented by general formula (I) or a pharmacologically acceptable salt thereof as the active ingredient, and a novel indolocarbazole derivative.  
WO/1994/004541A2
This invention describes both known and novel compounds, some of which are protein kinase inhibitors, that may be combined with taxol type compounds. The combination of disclosed compounds plus taxol type compounds exhibits powerful syne...  
WO/1993/018040A1
Compounds are described of formula (I), wherein R1 represents a hydroxyl group or a group selected from -OCOCH=ECHCH(CH3)(CH2)3CH3, -OCOCH=ECHC(CH3)=ECHCH(CH3)CH2CH3 or -OCO-X-CH2CH(CH3)CH2CH3 [where X is -CH=ECHCH(CH3)-, -CH2CH(OH)CH(CH...  
WO/1993/017689A1
A method and pharmaceutical for protecting against genotoxic damage in irradiated cells. Reduction of mutations at the hypoxanthine-guanine phosphoribosyl transferase locus is accomplished by administering an effective dose of a compound...  
WO/1993/018039A1
Compounds are described of formula (I), wherein R1 represents a hydroxyl group or a group selected from -OCOCH=ECHCH(CH3)(CH2)3CH3, -OCOCH=ECHC(CH3)=ECHCH(CH3)CH2CH3 or -OCO-X-CH2CH(CH3)CH2CH3[where X is -CH=ECHCH(CH3)-, -CH2CH(OH)CH(CH3...  
WO/1993/007904A1
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of formula (III), at least a stoichiometric amount of a base, e.g., NMG, an amount of, e.g., h...  
WO/1993/006112A1
The present invention relates to an antiviral phosphonate derivate of an acyclic purine nucleoside analog, to pharmaceutically acceptable derivatives thereof and to their use in medical therapy, particularly in the treatment of cytomegal...  
WO1992004359A3  
WO/1992/016530A1
Compounds are described of formula (I) wherein R1 represents a hydrogen atom or an acetyl group; R2, R3 and R4 may each independently represent a hydrogen atom or a methyl group; n represents an integer from 1 to 3; and the fluorine atom...  
WO/1992/014745A1
A solvent-free method for synthesizing an ethereally-substituted, blocked monosaccharide comprising the steps of: 1) mixing, in the absence of solvent, a partially blocked monosaccharide unblocked at one position, an alkyl halide or a su...  
WO/1992/012160A1
These compounds inhibit the enzyme squalene synthase and/or are intermediates for the preparation of compounds which inhibit the enzyme squalene synthase. Compounds of the invention may be formulated for use in a variety of conditions wh...  
WO/1992/009276A1
The use of compounds of formula (I) for the treatment of cells having an abnormally elevated cell proliferation, which results in diseases such as psoriasis, inflammatory diseases, rheumatic diseases and allergic dermatologic reactions.  
WO1992005152A3  
WO1991018911A3  
WO/1992/005152A2
A process for converting 1,4- and 1,5-dicarbonyl sugars to pyrrolidine and piperidine amino sugars. Novel compounds resulting from this process are also described.  
WO/1992/004359A2
Derivatives of simple monosaccharides which exhibit anti-proliferative and/or anti-inflammatory activity and are useful for treating mammals having inflammatory disorders and/or autoimmune disorders. This invention also encompasses pharm...  
WO/1992/002525A1
A glucofuranose derivative substituted at the 3,5,6- or 3,6-positions with a radical that provides an anionic charge at physiological pH values is disclosed, as are pharmaceutical compositions, and methods of making and using the same. T...  
WO/1991/019728A1
A nucleotide derivative represented by general formula (I), which has an excellent pharmacological action and is obtained from a structural derivative other than naturally occurring normal cyclic nucleotides: wherein R1 represents hydrog...  
WO/1991/018911A2
This invention relates to a method of producing peracetyloxazolines from peracetyl saccharides. The method involves reacting the starting material, a peracetyl saccharide, with a reagent combination, to directly produce the peracetyl oxa...  
WO/1991/018910A1
A compound of general formula (I), in which each of R1, R2, R3 and R4 independently represent a hydrogen atom or a group -(CO)nR5 in which n is 0 or 1 and R5 represents an alkyl, aryl, cycloalkyl, alkaryl or aralkyl group, or R1 or R2 to...  
WO/1991/002739A1
Methods of stereoselectively preparing a substituted 1,2-anhydrosugar wherein a substituted glycal is converted into a 1,2-anhydrosugar that is utilized to glycosylate a hydroxyl group containing glycal, are disclosed. Methods of prepari...  
WO/1988/000951A1
Method of producing peracetyl oxazolines from peracetyl saccharides. The method involves reacting the starting material, a peracetyl saccharide, with a reactive compound, such as trifilic acid, to directly produce the peracetyl oxazoline.  
WO/1987/006592A1
The preparation method comprises the reaction of an aldose or a polyaldoside in hydrogen fluoride, in the presence of water or not, and is characterized in that the concentration of aldose or polyaldoside in the reaction, calculated when...  
WO1987002366A3  
WO/1987/002366A2
Novel derivatives of the oligosaccharide antibiotic complex 13-384, the derivatives being of general formula (I), wherein R is hydrogen or Z, where Z is a moiety of general formula (II) in which R1 is nitroso, N-hydroxylamino, N-acyl-N-h...  
WO/1987/000529A1
Sugar-containing dipeptides of a new type, their manufacture and use in various pharmaceutical, biological and medical applications, in particular for prophylactic purposes against infections, combating infections diseases of various ori...  
WO/1986/005186A1
Selective esterification of only one of the hydroxy groups in polyols is achieved using an acetalized or a ketalized polyol as the starting material and an enzyme catalysing esterification. Furthermore, the selective esterified polyols m...  
WO/1985/000814A1
The invention relates to a process for the dehydration of glucids, which is applicable to glucids of which the molecule comprises at least one unit of the ketose type, characterized in that the glucid is reacted without addition of water...  
WO/1980/002112A1
Novel heterocyclic anthracycline compounds having antitumor activity against murine P388 leukemia in mice.  
WO/1979/001068A1
Novel arabinofuranosyl nucleosides and nucleotides having 2'-azido, 2'-amino, or 2'-hydrocarbylamino substituents, which have antitumor, antiviral, and antimicrobial properties, are prepared by condensation of a pyrimidine, purine, or 1,...  
WO/1979/001088A1
New glucosamin silyl compounds of formula: (FORMULA) wherein X is a carbonyl group, R1, R4 and R6 a tri-alkyl-lower-sylil group, in particular trimethyl-silyl, R2 is an alkyl group eventually substituted or an aryl carbocylic group, R3 i...  
JP2020059728A
[Subject] Offer of a Harri Condo Lynne B analog useful as an anticancer agent, especially an efficient new synthesizing method of Eribulin. [Means for Solution] It is the method of preparing an intermediate in composition of Eribulin, an...  
JP2020055786A
[Subject] Offer of a compound for endo-beta-N-acetylglucosaminidase active detection. [Means for Solution] It is Z about combination of a fluorescence machine which fluorescence resonance energy movement (FRET) produces, and an optical q...  
JP2019534313A
The present invention is aimed at a useful diazaspiro [4.5] Deccan intermediate and its salt to prepare tryptophan hydroxylase (TPH) and the spiro loop compound which is especially inhibitor of isoform 1 (TPH1). The method of preparing a...  
JPWO2018143140A1
General formula (1A):The inside of [type and Y are carbonyl group, sulfonyl group, substitution, or unsubstituted Al Killen machine;R.1And R2same in Is or differing -- hydrogen atom or hydroxyl group;R3Is a hydrogen atom, substitution, a...  
JP2019520342A
The present invention describes the new conjugate of formula (I) of a medicine combinable with the glucose perception protein which enables reversible discharge of a medicine according to glucose concentration, and a portion.  
JP6455857B2  
JP2018203621A
To provide novel amide compounds modified with N-linked sugar chain.The amide compound modified with N-linked sugar chain of the invention is represented by Formula (1). The cyclic structure Ain Formula (1) is a sugar or sugar derivative...  
JP2018199706A
To provide a novel oligosaccharide or polysaccharide containing a 1,2-cis form of amino sugar.The present invention provides a sugar chain compound described in (g), the sugar chain compound containing a 1,2-cis form of sugar residue. (g...  
JP2018535237A
The present invention is a glucopyranosyl derivative as sodium dependency glucose cotransporter (SGLT) inhibitor, and a complex of L-pyroglutamic acid, And it is related with those use in manufacture of the medical supplies for treating ...  
JP2018534312A
The present invention is the following formula,Inside of a formula, R1And R2It Is and becomes independent and they are H and C.1~C6It can be Alkyl , for example, methyl, ethyl, propyl, butyl, Aryl , for example, phenyl, and Para - methox...  
JP2018145108A
To provide: a method of chemically synthesizing α(1→4) glycoside cyclic trimers and tetramers; and α(1→4) glycoside cyclic trimers and tetramers that have not been synthesized before.The present invention provides α(1→4) glycosi...  
JPWO2017034004A1
[Subject] Provide a new gelling agent containing a sugar derivative. [Means for Solution] A gelling agent which consists of a compound denoted by following formula (1) or a formula (2). [Formula 1]Inside of [type, R1Straight chain shape ...  
JP6370490B2  
JPWO2017047816A1
The present invention provides the intermediate compound for the manufacturing method of guanidine bridge construction type artificial nucleic acid (it abbreviates to GuNA hereafter), and its manufacture. Specifically, the present invent...  
JP6347742B2  
JP6342968B2  

Matches 201 - 250 out of 848