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JP2884511B1 |
[wrap up] [Constitution] The present invention exhibits a growth inhibitory effect on a wide range of plants with respect to the novel compounds represented by the formulas (I) and (II), and is therefore useful as a plant production inhi...
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JPH1160593A |
To obtain new glycolipids useful as anti-inflammatory drugs having lower toxicity than heretofore by comprising compounds having cholesterols or octyl groups bonded to oligosaccharides of the specific monosaccharides excluding neohesperi...
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JPH11500133A |
Certain benzopyran antiestrogens are disclosed for treating estrogen sensitive diseases such as breast cancer. Prodrug forms provide ease of manufacturing, good shelf life, and bioavailibility.
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JPH10310598A |
To obtain the subject new compound comprising a specific sterol compound capable of efficiently and stereoselectively synthesizing by organic synthetic chemical method, having excellent in vivo antitumor action and useful as a medicine s...
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JP2813610B2 |
Compounds of formula I wherein: R1 is hydrogen or hydroxy, and the methyl and hydroxy groups at 6- and 7-positions respectively can be either in alpha or beta configuration, are useful in human therapy. Compounds I are prepared by methyl...
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JPH10251294A |
To obtain the subject new compound, comprising a specific cis-sterol compound capable of being efficiently and stereoselectively synthesized according to an organic synthetic chemical method using deoxycholic acid as a raw material, havi...
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JP2793279B2 |
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JP2784846B2 |
Inhibitors of sex steroid activity, for example those having the general structure may be used as part of a pharmaceutical composition to provide antiestrogenic effects and/or to suppress estrogen synthesis. Such pharmaceutical compositi...
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JP2779011B2 |
The present invention relates to specific ligands for estrogen or progestagen steroid hormone receptors which have the formula (I) in which X denotes a vinyl group substituted by a radioactive or nonradioactive halogen on the double bond...
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JPH10506638A |
PCT No. PCT/US96/06505 Sec. 371 Date Nov. 4, 1997 Sec. 102(e) Date Nov. 4, 1997 PCT Filed May 8, 1996 PCT Pub. No. WO96/35407 PCT Pub. Date Nov. 14, 1996Alendronate, a bisphosphonate can prevent tooth loss not necessarily associated with...
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JPH10177024A |
To obtain a purified human ouabain that is useful as diagnosis agents such as a hypertension diagnosis agent, a congestive cardiomyopathy diagnosis agent, and a renal insufficiency diagnosis agent. Human plasma or serum are dialyzed and ...
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JP2760870B2 |
PCT No. PCT/EP89/01090 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 20, 1989 PCT Pub. No. WO90/03385 PCT Pub. Date Apr. 5, 1990.New 11 beta -phenyl-14 beta H-steroids of general formula (I), where Z is an oxy...
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JPH10130161A |
To obtain the subject composition having an excellent antibacterial action on Helicobacter pylori, high preventive effect on the infection with Helicobacter pylori by containing a specific material, a free fatty acid, etc., as active ing...
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JP2731563B2 |
Substantially pure saponins are disclosed. The saponins of the present invention are useful as immune adjuvants. Disclosed as well are immune response-provoking compositions comprising an antigen in admixture with the substantially pure ...
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JPH1072487A |
To obtain a new sterol compound consisting of a specific sterol compound capable of being synthesized by an organic synthetic chemical method in a good efficiency and also stereoselectivity, having a growth inhibiting effect on tumor cel...
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JP2723630B2 |
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JP2718834B2 |
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JPH09512270A |
The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglyco...
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JP2687209B2 |
A novel steroid of the formula I wherein X is methylene and R is an optionally substituted carbocyclic aryl or heterocyclic aryl or optionally substituted vinyl or ethynyl or X is a simple bond or -S- and R is optionally substituted carb...
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JP2677626B2 |
The invention relates to new 17-hydroxy androsta-1,4-diene-3-one derivatives of the following formula wherein each of R and R3, independently, is hydrogen or C1-C6 alkyl; R1 is hydrogen, halogen or C1-C6 alkyl; R2 is hydrogen or C1-C6 al...
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JP2674957B2 |
PURPOSE: To analyze an objective compound for analysis, capable of performing a high level judgment, at a high sensitivity, safely at a low cost and also in a wide application range by using a labeled compound emitting an electromagnetic...
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JPH09511214A |
The present invention relates to DELTA 16 unsaturated steroids which are useful as steroid C17-20 lyase inhibitors.
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JP2664390B2 |
The invention relates to 11-aryl steroid derivatives, having the structure wherein: R1 is a homocyclic or heterocyclic aryl group having one of the following substituents: an optionally saturated or unsaturated, branched or unbranched hy...
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JP2660404B2 |
1. The products of formula I : see diagramm : EP0245170,P90,F1 in which R1 represents an alkynyl radical having from 2 to 8 carbon atoms optionally substituted by a radical selected from the radicals, hydroxyl, halogen, trialkylsilyl, al...
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JPH09509959A |
Compounds having a broad range of antimicrobial activity generally have a structure including a steroid nucleus with a cationic, preferably polyamine, side chain (X) and an anionic side chain (Y). The invention is also directed to compou...
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JP2648474B2 |
To obtain a novel compound consisting of a specific Ru complex containing a 2,2'-bipyridine compound as a ligand, emitting electromagnetic radiations, when receiving an electrochemical energy, and useful for analysis as an electrochemica...
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JPH09221496A |
To obtain a new steroidal compound exhibiting strong cell toxicity to a cancerized cell and useful as a medicine, etc., such as a carcinostatic agent or an antitumor agent by separating and purifying an extract obtained by extracting Cle...
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JP2642089B2 |
Bile acid derivatives of the formula I W-X-G in which G is a bile acid residue, W is an active substance portion of a medicament and X is a linker between bile acid residue and active substance portion, are outstandingly suitable for int...
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JP2642090B2 |
Bile acid derivatives of the formula I W-X-G in which G is a bile acid residue, W is an active substance portion of a medicament and X is a linker between bile acid residue and active substance portion, are outstandingly suitable for int...
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JPH09208597A |
To obtain a (24R)-24,25-dihydroxysteroid compound in a high yield in a highly excessive diastereomer rate by subjecting a specific steroid compound to a catalytic dihydroxylation reaction in the presence of a specified osmium complex in ...
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JP2636208B2 |
To obtain a new steroidal glycoside useful for pharmaceutical compositions used for the treatments of certain cancer conditions, as well as geriatric disease, states of hyperactivity and states of diminished activity, and so on. New 3β-...
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JP2617706B2 |
New steroid compounds of the general formula: (A) wherein X is a hydroxyl group and Y is a hydrogen atom, or X and Y, taken together, form an oxo group; each of the two R' radicals is independently a hydrogen atom, acyl group, a silyl gr...
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JP2612123B2 |
Novel glycosides, especially steroidal glycosides, and a novel method of their production, are provided. For the novel method of producing novel glycosides, hydroxysteryl compounds are glycosylated with tri-O-acyl glucal using molecular ...
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JP2593540B2 |
PCT No. PCT/DE88/00149 Sec. 371 Date Nov. 13, 1989 Sec. 102(e) Date Nov. 13, 1989 PCT Filed Mar. 11, 1988 PCT Pub. No. WO88/07050 PCT Pub. Date Sep. 22, 1988.The invention relates to a process for the production of (+)-bicyclo[3.3.0]octa...
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JPH09502982A |
The present invention relates to oligosaccharide-containing 14-aminosteroid compounds and the pharmaceutically-acceptable acid salts or esters thereof of the general formula: wherein a) R1 is (i) COOR5, where R5 is hydrogen, a 1-6 carbon...
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JPH0948794A |
To obtain a new steroid glycoside which obtained by extraction of a plant in liliaceae plant and is a specific steroid glycoside, shows high anticancer action and high immunosuppression with high safety and is useful as an active ingredi...
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JPH0930977A |
To obtain the subject therapeutic agent comprising an extract of black cohosh root as active ingredient, suppressing bone absorption by parathyroid hormone and reduction in bone density, having no adverse effect, useful for treating oste...
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JP2568306B2 |
Bile acid derivatives of the formula I W-X-G in which G is a bile acid residue, W is an active substance portion of a medicament and X is a linker between bile acid residue and active substance portion, are outstandingly suitable for int...
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JPH092957A |
PURPOSE: To obtain the subject agent, containing a sialic acid derivative having a specific amide bond as an active ingredient, having ameliorating actions on disorder in peripheral nervous systems such as diabetic neuropathy and effecti...
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JPH092956A |
PURPOSE: To obtain a therapeutic and preventing agent, containing a sialic acid derivative having a specific amide bond as an active ingredient, capable of preventing neuron death due to glutamic acid and effective in preventing and trea...
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JPH092955A |
PURPOSE: To obtain a suppressant, comprising an ecdysteroid analog, having both differentiation promoting and division suppressing actions on keratinocytes sufficient to ameliorate psoriasis and high safety and effective in preventing an...
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JP2566384B2 |
PCT No. PCT/US93/02812 Sec. 371 Date Dec. 20, 1994 Sec. 102(e) Date Dec. 20, 1994 PCT Filed Apr. 2, 1993 PCT Pub. No. WO94/00479 PCT Pub. Date Jan. 6, 1994Processes for the synthesis of tigogenin beta-O-cellobioside heptaalkanoate which ...
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JPH08333386A |
PURPOSE: To obtain a new steroid derivative useful for medicines having an antitumor action, etc. CONSTITUTION: A compound of formula I (R is a 1-4C alkyl; X, Y are hydroxyl group, a group capable of being easily hydrolyzed to form the h...
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JP2545522B2 |
This invention provides novel tetrahydro steroids which are useful in inhibiting angiogenesis and have the following structure: A compound of the formula: wherein R1 is beta -CH3 or beta -CH2H5; wherein R2 is H, and R3 is =0, -OH, -0-alk...
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JP2547322B2 |
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JPH08259590A |
PURPOSE: To obtain a therapeutic agent for hyperlipemia comprising PF1,032 substance or its salt as the active ingredient, having lowering action on triglyceride and cholesterol in blood, low side effect, effective for treating arteriosc...
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JPH08225590A |
To obtain the subject new compound, a specific steroid with a 17- spiromethylene lactone group or the like, with low affinity for a progesterone receptor and slight side effects, and usable as a contraceptive, or in treating menstrual di...
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JP2525049B2 |
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JPH08140672A |
PURPOSE: To obtain a large amount of CHIKUSETU (Panax) saponin which is useful for treating thrombosis, stress ulcer and other diseases by inoculating Agrobacterium rhizogenes to stem pieces of sterilized callus of TOCHIBA NINJIN (Panax ...
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JP2501650B2 |
PCT No. PCT/SE89/00528 Sec. 371 Date May 21, 1991 Sec. 102(e) Date May 21, 1991 PCT Filed Sep. 28, 1989 PCT Pub. No. WO90/03184 PCT Pub. Date Apr. 5, 1990The invention claims an iscom matrix which is not a lipid vesicle comprising at lea...
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