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JPH064671B2 |
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JPH05310576A |
PURPOSE: To provide an antitumor agent containing a specified hydrocortisone analog as the active component, low in toxicity and glucocorticoid effect, capable of high dosege administration over a long period and excellent in vasculariza...
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JPH05296999A |
PURPOSE: To accurately measure the concentration of human lipocortin I contained in a blood serum or blood plasma (hereinafter omitted) by determining the human lipocortin I as a marker for discriminating the effect of glucocorticoid. CO...
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JPH05294990A |
PURPOSE: To provide the novel digoxin derivative comprising a digitoxose whose 3' and 3" positions have been esterified with succinic acid and useful as a raw material for producing a digoxin-resistant antibody used for the determination...
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JPH05286992A |
PURPOSE: To obtain the subject compound for treating rheumatic arthritis, consisting of a sialic acid ester of a steroid such as cortisone, dexamethasone or vitamin D3, reduced in side effects and having antiphlogistic action and antiall...
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JPH0569103B2 |
New 24-homo-vitamin D compounds, methods for preparing the same and novel intermediate compounds. The compounds are characterized by vitamin D-like activity of the order of 1 alpha ,25-dihydroxyvitamin D3, the recognized circulating horm...
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JPH0564614B2 |
The invention relates to the use of phytosterol glycosides (phytosterolins) and their esters for the prevention and treatment of increased endogenous 5(6) a-epoxycholesterol levels in human and animal organs or organ fluids, especially t...
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JPH0544959B2 |
17-Substituted-21-hydroxy or 21-acylated steroids are prepared from 20-enol steroids in two steps, the first comprising reaction with peroxymonosulfate ion in a biphasic phase-transfer-catalysed medium (which can give novel 20,21-epoxy-c...
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JPH05503294A |
PCT No. PCT/DE91/00623 Sec. 371 Date Jun. 18, 1992 Sec. 102(e) Date Jun. 18, 1992 PCT Filed Aug. 1, 1991 PCT Pub. No. WO92/03465 PCT Pub. Date Mar. 5, 1992.20 -Methyl-5,7-pregnadiene-3 beta ,21-diol derivatives of general formula I (I) i...
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JPH0532369B2 |
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JPH0592988A |
PURPOSE: To obtain new compds. useful as intermediates giving 16β-methyl-17- keto steroids as starting materials for methyl corticoids in high yields. CONSTITUTION: The new compds. are compds. of the formula (where R16 and R16' are indi...
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JPH0518840B2 |
This invention relates to hydroxylated derivatives of vitamin D2, to processes for preparing such compounds, to intermediates utilized in such processes and to certain isotopically labelled vitamin D2 compounds. The vitamin D2 derivative...
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JPH0518838B2 |
Two processes are disclosed (one-pot and two-pot) for the transformation of a 6 beta -fluoro- DELTA 1,4-3-keto steroid (IV) to a 6 alpha -fluoro- DELTA 1,4-3-keto steroid (VI). These processes permit the introduction of a fluorine atom a...
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JPH0518839B2 |
This invention relates to hydroxylated derivatives of vitamin D2, to processes for preparing such compounds, to intermediates utilized in such processes and to certain isotopically labelled vitamin D2 compounds. The vitamin D2 derivative...
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JPH054397B2 |
Novel 3-keto-19-nor- DELTA 4,9-steroids of the formula I
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JPH054998A |
PURPOSE: To provide the title new compound found in an extract from sponge belonging to Xestospongia, having in the molecule both cyclopropane ring and oxirane ring, having antineoplastic activity, thus useful for e.g. the therapy of leu...
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JPH05500057A |
(57) [Summary] Since this publication is application data before electronic filing, summary data is not recorded.
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JPH04364130A |
PURPOSE: To provide the subject food (beverage) incorporated with γ- cyclodextrin, substantially improved in an offensive taste ot soya saponin solubility and solution stability thereof, easier to take in, also excellent in the quality ...
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JPH0477758B2 |
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JPH04506669A |
Polyoxoheterocyclic tetracycles related to the Chinese antimalarial natural product qinghaosu (artemisinin) are disclosed. These materials have a core structure with an oxygen (carbonyl or alkyl ether) at position 12 and in some cases on...
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JPH04331284A |
PURPOSE: To obtain lipid-selective antioxidants useful for the prophylaxis and treatment of coronary and circular diseases by reacting respectively specific antioxidative components and lipophilic components with bridging members. CONSTI...
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JPH0469638B2 |
The invention discloses 4-substituted androstendione derivatives of the following formula (I) (I) wherein R is amino or substituted amino or azido, one of R1 and R2 is hydrogen and the other is hydrogen, alkyl, alkenyl or alkynyl, and (x...
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JPH04290899A |
PURPOSE: To obtain a new cardenolide compound, composed of a glycoside, extracted and isolated from a herb medicine teen-ped grown in Thailand, having cardiotonic activity and useful as a therapeutic agent for improving cardiac insuffici...
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JPH0460119B2 |
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JPH0460118B2 |
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JPH0460120B2 |
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JPH04266878A |
PURPOSE: To industrially and advantageously obtain the subject compound by reacting a specific double bond-containing compound with an oxygen-containing gas in the presence of a manganese compound and an aldehyde compound. CONSTITUTION: ...
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JPH0457679B2 |
This invention relates to the synthesis of steroids which are useful for their biological activity or which may be converted to steroids which have such activity. More particularly, the invention pertains to the synthesis of 24,25-dihydr...
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JPH04505155A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPH04504572A |
A method of inhibiting hair growth in mammals which comprises the topical administration of a composition comprising an anti-angiogenic effective amount of an angiostatic compound of formula (I). The formula (I) compound is present in an...
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JPH04504414A |
PCT No. PCT/US90/00121 Sec. 371 Date Sep. 13, 1991 Sec. 102(e) Date Sep. 13, 1991 PCT Filed Jan. 12, 1990 PCT Pub. No. WO90/08315 PCT Pub. Date Jul. 26, 1990.Ginsenosides Rb1 and Rg1 enhance the availability of acetylcholine in the corti...
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JPH0443918B2 |
DELTA <4>-3-keto, DELTA <1,4>-3-keto and 3 beta -hydroxy-17-keto-steroids are transformed into the corresponding 16 beta -methyl-17-keto-steroids by activating the C-16 position, metylating, and reacting with a strong base. The C-3 posit...
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JPH0443916B2 |
This invention relates to hydroxylated derivatives of vitamin D2, to processes for preparing such compounds, to intermediates utilized in such processes and to certain isotopically labelled vitamin D2 compounds. The vitamin D2 derivative...
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JPH0443920B2 |
Novel 3-keto-19-nor- DELTA 4,9-steroids of the formula I
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JPH0440360B2 |
The present disclosure is directed to a process and intermediates for the synthesis of Vitamin D3 metabolites such as 1,25-dihydroxycholecalciferol, 25-hydroxycholecalciferol and 24R,25-dihydroxycholecalciferol from 17-keto steroids via ...
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JPH04503361A |
The process of the present invention is a process for the preparation of an 11-oxygenated steroid of formula (II) which comprises (1) contacting a 9 alpha -halo steroid of formula (I) with a metal selected from the group consisting of ti...
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JPH0435458B2 |
This invention relates to hydroxylated derivatives of vitamin D2, to processes for preparing such compounds, to intermediates utilized in such processes and to certain isotopically labelled vitamin D2 compounds. The vitamin D2 derivative...
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JPH0434540B2 |
This invention relates to hydroxylated derivatives of vitamin D2, to processes for preparing such compounds, to intermediates utilized in such processes and to certain isotopically labelled vitamin D2 compounds. The vitamin D2 derivative...
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JPH0432840B2 |
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JPH0432839B2 |
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JPH04124197A |
NEW MATERIAL:A saponin, extracted from spinach with a hydrophilic solvent and having about 0.16-0.42 Rf value in silica gel thin-layer chromatography (solvent = chloroform : methanol : water = 6:4:1) with about 33-48mN/m surface tension ...
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JPH04103598A |
PURPOSE: To obtain the subject high-purity saponin excellent in workability and useful not only for foods but for cosmetics in high yield by removing high- molecular components by ultrafiltration and then recovering the objective saponin...
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JPH0414680B2 |
A multistep process for production of 17 alpha -acetoxy-1,2-methylene-4,6-pregnadiene-3,20-dione involves ketalization of the 20-keto group of 17 alpha -hydroxy-1,4,6-pregnatriene-3,20-dione, then methylenation in the 1,2-position with t...
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JPH047757B2 |
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JPH0441429A |
PURPOSE: To obtain a carcinostatic agent, containing a saponin of starfishes and capable of exhibiting remarkable inhibitory effects on proliferation of tumorous cells. CONSTITUTION: An inhibitor containing ovarian.asteroaponin-4 (OA-4),...
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JPH047758B2 |
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JPH047325B2 |
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JPH047327B2 |
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JPH047326B2 |
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JPH0372238B2 |
The invention provides methods for preparing the various isomeric forms of 25-hydroxyvitamin D3-26,23-lactone utilizing cyanohydrin formation with readily prepared steroid materials followed by actinic radiation of the products and recov...
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