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JP2011121926 |
To provide a composition which includes at least either one of protopanaxatriol (PPT) and protopanaxadiol (PPD), both having physiological activity such as anticarcinogenic activity, anti-inflammatory activity and saccharometabolism regu...
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JP2011102321 |
To provide a medical preparation which can maximize the effect of a cholestanol glycoside useful as an antitumor agent.There is provided an anticancer agent containing a liposomal glycoside obtained by adding an organic solvent and water...
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JP2011057585 |
To pay an attention on sterol glycosides contained in germinated unpolished rice to clarify a new action mechanism thereof.There are provided an antidepressant agent containing sterol glycosides originated from germinated unpolished rice...
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JP2011026314 |
To provide a highly safe and highly stable carbohydrate metabolism-improving agent having excellent blood glucose level-regulating actions and carbohydrate metabolism-improving actions, and ingestible as a food or drink; and to provide a...
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JP2011026313 |
To provide a highly stable carbohydrate metabolism-improving agent having excellent blood glucose level-regulating actions and carbohydrate metabolism-improving actions, and to provide a carbohydrate metabolism-improving composition cont...
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JP2010280701 |
To provide a pharmaceutical formulation for administration by inhalation having a therapeutically useful effect in the treatment of inflammatory disorders of the respiratory tract.The pharmaceutical formulation containing a compound of f...
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JP2010100529 |
To provide an ADHD-related disease medicine exhibiting simple and high effects.There is provided a compound of structural formula (1), wherein R1 and R2 are each independently H, OH, a sugar moiety, or the like.
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JP2010095528 |
To provide a non-thermally reversible photochromic compound.The invention relates to a photochromic compound which may be thermally reversible or non-thermally reversible, and the like. The invention also relates to a photochromic dichro...
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JP2010077145 |
To provide a novel androstane anti-inflammatory and antiallergic compound and a method of preparing the same.This compound is represented by formula (I), and solvates of the same, compositions containing the compound, a method of prepari...
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JP2009256388 |
To provide a new hybrid drug for cancer treatment and for releasing the drug by setting a target on cancer cells.Provided is a hybrid drug for cancer treatment, having a targeting moiety specifically bonding with proteins, receptors and ...
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JP2009102226 |
To provide a drug for recovery from a spinal cord injury recovery exhibiting simple and high effects, to provide a food, a medicine composition containing the same, and to provide a spinal cord injury recovery method.Provided is Withanos...
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JP2009046441 |
To provide a new cholesterol derivative having little toxicity to a living body, having a high encapsulation rate, and high solubility in supercritical carbon dioxide, providing excellent contrastradiography not only of the systemic bloo...
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JP2009035552 |
To provide 17-esters of 9,21-dihalo-pregnane-11,17-diol-20-one.An improved process for the preparation of 17-esters of 9,21-dihalo-pregnane-11,17-diol-20-one is provided. This new process is especially appropriate for the preparation of ...
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JP2008285497 |
To provide a corticosteroid effective in treating disorder of airway passage and lung such as asthma, manifesting a low bioavailability and low systemic side effect in administering by an intranasal administration or oral inhalation.The ...
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JP2008285448 |
To provide a new sialidase inhibitor effective for inhibiting the activity of sialidase of influenza virus, etc.The sialidase inhibitor is composed of a derivative obtained by introducing a substituent having an aromatic ring on the 9-si...
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JP2008195667 |
To provide a 2-6 sialyl 6-sulfo sugar chain compound bonded with a lipid, or its salt, usable as an anticancer agent and an immunoregulating agent.This compound having a 2-6 sialyl 6-sulfo sugar chain bonded with cholestanol, cholesterol...
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JP2008139299 |
To provide a probe capable of detecting a membrane microdomain or a cholesterol recognition protein sensitively and precisely.An amidated cholesterol is used, which is labeled by one selected from a group consisting of biotin, benzopheno...
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JP2008031184 |
To provide corticosteroid effective on the therapy in the treatment of diseases of airway passages and lungs such as asthma, and exhibiting low bioavailability and low systemic side effects when administered by intra-nasally or oral inha...
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JP2007145782 |
To obtain an extract having high blood sugar level depressing action from Momordica charantia of a natural plant, and to provide a blood sugar level depressant containing the same, and a food/pharmaceutical composition containing this ex...
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JP2007126466 |
To provide an enzyme inhibition immunoassay for the measurement of an analyte in biological samples.This invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to...
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JP2007051148 |
To provide a new steroid compound useful as an anti-estrogenic agent.The new steroid compound is a 17-desoxy-1,3,5(10)-estratriene, being such that a molecular moiety of the chemical formula is substituted at the C-11 or C-17 position on...
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JP3902255 |
To provide the subject new compound having excellent antiinflammatory action and low systemic side actions and useful e.g. for an extremely strong local antiinflammatory agent by reacting deoxymethasone, etc., with an activated aromatic ...
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JP2006312649 |
To provide a formulation for treatment of asthma free from CFC and a process for preparing the same, having desired solubility, stability, low toxicity, practical dosage, accurate particle size (in suspension) and/or avoiding defects man...
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JP2006176428 |
To develop drug(s) in view of the fact that neurodegenerative diseases including Alzheimer's disease, senile dementia, cerebrovascular dementia and Parkinson's disease means symptoms presenting disorders in memory and/or cognizance by ne...
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JP2006151994 |
To provide a simple method for converting a pregnane-3,20-dione compound into a 3α-hydroxy-3β-substituted-pregnane.An unprotected dione is chemoselectively and stereoselelctively converted into a 3(R)-pregnane-3-spiro-2'-oxiran-20-one ...
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JP3814312 |
PURPOSE: To obtain the subject new derivative having anti-glucocorticoid activity and usable in treating or preventing glucocorticoid-dependent diseases such as diabetes, hypertension and arteriosclerosis. CONSTITUTION: This new 11,12-bi...
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JP3793602 |
To obtain a new steroid glycoside which is obtained by extraction of a plant in liliaceae plant and is a specific steroid glycoside, shows high anticancer action and high immunosuppression with high safety and is useful as an active ingr...
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JP3780007 |
PURPOSE: To obtain a corticosteroid 17-alkyl carbonate 21-[0]-carboxylic acid carbonic ester which has a very strong local and topical anti-inflammatory action and is effctive in treating inflammatory dermatosis by reacting a specific al...
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JP3778372 |
PURPOSE: To obtain a new compound useful as a therapeutic agent for geriatric dementia, etc., including Alzheimer's disease, due to its activity of activating ChAT in cholinergic neurocytes. CONSTITUTION: A compound of formula I [R1 is a...
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JP3779744 |
PURPOSE: To obtain a new monosaccharide derivative comprising a monosaccharide derivative having a sterol residue and a polyoxyethylene chain, and capable of prolonging a residence time of medicine in blood when being blended with the me...
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JP2005179370 |
To provide a method and to obtain a composition for causing the interaction with a GABAA (γ-aminobutyric acid A) receptor complex to induce sleep in Homo sapiens.In the sleep induction method, a 3α-hydroxy-5-reduced steroid derivative ...
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JP2004277312 |
To provide a new ligand which enables the simple and rapid detection of a target base sequence in a homogeneous system not needing a B/F separation treatment in an aptamer method for detecting a target base sequence with the bonding affi...
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JP2004155740 |
To provide a method for simply measuring bond strength of a chemical substance to an androgen receptor.A fluorescent ligand is represented by formula (1) [wherein n is an integer of 4-8]. The method for measuring the bond strength compri...
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JP2004149457 |
To obtain a prophylactic or a therapeutic agent for liver diseases, comprising an extracted solution or essence as an active ingredient having inhibitory action on hepatopathy contained in the flower part of a plant of the family Araliac...
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JP3535588 |
PURPOSE: To obtain ginsenoside Rh2 useful as raw material for a medicine such as a carcinostatic agent and a perfume by oxidizing a specific terpene with a carbonyl compound, acetylating, reducing, reacting the resultant substance with a...
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JP3509812 |
To provide an electrochemiluminescence label and an assay using the same. An agent which emits electromagnetic radiation when receiving electrochemical energy is bonded to the object of analysis, and the electrochemical energy is generat...
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JP2003342291 |
To obtain an estradiol conjugate used as a surrogate compound which makes it possible to conduct microanalysis of an estradiol conjugated by glucuronic acid or sulfuric acid with high accuracy and high reliability, and to provide a metho...
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JP2003313128 |
To obtain a corticosteroid therapeutically effective in treating diseases of the airway passages and lungs such as asthma and also exhibiting low bioavailability and low systemic side-effects when it is administered intranasally or by or...
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JP3476157 |
PURPOSE: To provide the subject new compound having an activity to inhibit absorption of bile acid in the small intestine and useful as a lipid level lowering agent to lower the level of cholesterol and the like by reacting bile acid wit...
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JP3476679 |
To safely and inexpensively detect the presence of the analyte in a sample with high sensitivity by detecting the electromagnetic radiation emitted from a reagent to which a constant quantity of electrochemical energy is applied. When a ...
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JP2003252895 |
To provide a sweetening with a high degree of sweetness, having lower energy than saccharose, having a good quality of taste close to that so saccharose and high safety, and having physiological and physical properties equal to that of t...
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JP2003128689 |
To provide an electrochemiluminescence label and an assay using the same.An agent which emits electromagnetic radiation when receiving electrochemical energy is bonded to the object of analysis, and the electrochemical energy is generate...
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JP2003063989 |
To provide an agent for overcoming tolerance of anticancer medicine to carcinoma cells by BCRP (Boreal Caribou Research Program) containing the effective ingredients having steroid hormones, compounds having female hormone action or comp...
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JP2003026591 |
To provide a specific anoretic agent, to provide a method for producing the anoretic agent by its synthesis, to provide an appetite suppressant composition containing the anoretic agent, and to provide an anorexiant.A compound represente...
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JP2002322168 |
To provide pharmaceutical compounds which reduce undesirable effects occurred at the region where is apart from the target site.Pharmaceutical compounds represented by general formula (I) or their salts or solvates, which are effective i...
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JP2002249498 |
To provide preparations for intravenous administration, liniments for the skin and membranes, and other skin and membrane care preparations or make-up preparations and fertilizing components, based on new ginesenosides derivatives especi...
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JP2002234897 |
To provide a new compound that bears an ether bond and an epoxy group on the side chain because vitamin D and derivatives thereof have important physiological activity and proliferation inhibitory action, but it has undesirable side effe...
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JP3343063 |
To obtain the subject new derivative useful for a preventive/ therapeutic agent for diseases observed to have hyaluronic acid abnormal decomposition and decomposition accentuation, an inhibitor against hyaluronic acid decomposition, a pr...
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JP2002205997 |
To obtain a specific anorectic agent, to provide a method for producing the anorectic agent by synthesis, to obtain an anorectic composition containing the above agent, and to provide an anorectic method.The anorectic agent is a compound...
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JP2002167330 |
To provide a skin whitening external preparation with excellent skin whitening effect and a melanogenesis inhibitor with excellent melanogenegsis inhibition.This skin whitening external preparation contains more than one or two withanoli...
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