| Document |
Document Title |
|
JP09002956 |
PURPOSE: To obtain a therapeutic and preventing agent, containing a sialic acid derivative having a specific amide bond as an active ingredient, capable of preventing neuron death due to glutamic acid and effective in preventing and trea...
|
|
JP09002955 |
PURPOSE: To obtain a suppressant, comprising an ecdysteroid analog, having both differentiation promoting and division suppressing actions on keratinocytes sufficient to ameliorate psoriasis and high safety and effective in preventing an...
|
|
JP08333386 |
PURPOSE: To obtain a new steroid derivative useful for medicines having an antitumor action, etc. CONSTITUTION: A compound of formula I (R is a 1-4C alkyl; X, Y are hydroxyl group, a group capable of being easily hydrolyzed to form the h...
|
|
JP08283285 |
PURPOSE: To obtain the subject new glycolipid containing a specific oligosaccharide bound to a ceramide, cholesterol or octyl group as a specific oligosaccharide, having antiinflammatory action, useful as a therapeutic agent for renal di...
|
|
JP08259590 |
PURPOSE: To obtain a therapeutic agent for hyperlipemia comprising PF1,032 substance or its salt as the active ingredient, having lowering action on triglyceride and cholesterol in blood, low side effect, effective for treating arteriosc...
|
|
JP08225590 |
To obtain the subject new compound, a specific steroid with a 17- spiromethylene lactone group or the like, with low affinity for a progesterone receptor and slight side effects, and usable as a contraceptive, or in treating menstrual di...
|
|
JP08217790 |
PURPOSE: To obtain a new monosaccharide derivative comprising a monosaccharide derivative having a sterol residue and a polyoxyethylene chain, and capable of prolonging a residence time of medicine in blood when being blended with the me...
|
|
JP08208688 |
PURPOSE: To obtain ginsenoside Rh2 useful as raw material for a medicine such as a carcinostatic agent and a perfume by oxidizing a specific terpene with a carbonyl compound, acetylating, reducing, reacting the resultant substance with a...
|
|
JP08140672 |
PURPOSE: To obtain a large amount of CHIKUSETU (Panax) saponin which is useful for treating thrombosis, stress ulcer and other diseases by inoculating Agrobacterium rhizogenes to stem pieces of sterilized callus of TOCHIBA NINJIN (Panax ...
|
|
JP08119866 |
PURPOSE: To obtain an antitumor agent by using a 3-keto compound of triterpenes as an active ingredient. CONSTITUTION: This antitumor agent comprises containing a 3-keto compound of oleanane-type triterpenes expressed by formula I (R is ...
|
|
JP08109192 |
To obtain a new steroidal glycoside useful for pharmaceutical compositions used for the treatments of certain cancer conditions, as well as geriatric disease, states of hyperactivity and states of diminished activity, and so on. New 3β-...
|
|
JP08099992 |
To provide the subject new compound having excellent antiinflammatory action and low systemic side actions and useful e.g. for an extremely strong local antiinflammatory agent by reacting deoxymethasone, etc., with an activated aromatic ...
|
|
JP08099991 |
To obtain modified bile acids having linker structure useful for hypoliplemics or the like by reacting bile acid ketone with acetylenic compounds, transforming into acetylide by a strong base, followed catalytic hydrogenation by Pd/C. Th...
|
|
JP08092277 |
To obtain a new bile acid derivative capable of being administered orally in a high dose, useful for the prevention and treatment of hyperlipidemia, etc., by converting a poorly absorbable therapeutic agent for cirrhosis to an absorbable...
|
|
JP08092276 |
To obtain a new bile acid derivative useful as an antihyperlipidemic, etc. by converting a non-absorbable therapeutic agent for cirrhosis to an absorbable agent. This bile acid derivative is a compound of the formula: W-X-G [G is formula...
|
|
JP08073340 |
PURPOSE: To obtain a skin external preparation excellent in skin whitening effect, good in both usability and safety, containing escinol and/or salt thereof (and tranexamic acid and/or arbutin). CONSTITUTION: This skin external preparati...
|
|
JP08034794 |
PURPOSE: To obtain a new sterol compound having excellent antineoplastic activity, useful as a medicine, etc., by chemical modification of aragusterols extracted and isolated from a sponge belonging to Xestospongia. CONSTITUTION: This ne...
|
|
JP07316187 |
PURPOSE: To obtain the subject new derivative having anti-glucocorticoid activity and usable in treating or preventing glucocorticoid-dependent diseases such as diabetes, hypertension and arteriosclerosis. CONSTITUTION: This new 11,12-bi...
|
|
JP07316185 |
PURPOSE: To obtain an intermediate for producing novel steroids having a 10-substituent and antiglucocorticoid activity and used for therapy or the like of the hypertension, glaucoma, atherosclerosis, osteoporosis, diabetes, immune depre...
|
|
JP07309836 |
PURPOSE: To analyze an objective compound for analysis, capable of performing a high level judgment, at a high sensitivity, safely at a low cost and also in a wide application range by using a labeled compound emitting an electromagnetic...
|
|
JP07267972 |
PURPOSE: To provide a novel compound useful for detection of enterotoxins and germs as an electrochemiluminescent labeling reagent. CONSTITUTION: This compound is represented by the formula: X-Y-Z [wherein X is a nucleotide, antibody, an...
|
|
JP07252294 |
PURPOSE: To obtain a new compound excellent in water solubility, having antiallergic activity, anti-inflammatory activity and antioxidizing activity, etc., thus useful for preventing or treating allergic diseases, inflammatory diseases, ...
|
|
JP07228592 |
PURPOSE: To obtain a new compound useful as a therapeutic agent for geriatric dementia, etc., including Alzheimer's disease, due to its activity of activating ChAT in cholinergic neurocytes. CONSTITUTION: A compound of formula I [R1 is a...
|
|
JP07224087 |
PURPOSE: To obtain a new steroid derivative efficiently and stereoselectively synthesizable by synthetic organic chemical technique without the need for using natural substance-derived materials with problems such as concerning resource ...
|
|
JP07196684 |
PURPOSE: To provide new steroid compounds of substituted 2β-morpholino- androstane derivatives having very potent anaesthetic activity and fast onset times and ideal sleep duration vs. recovery to full coordination profiles which are us...
|
|
JP07173188 |
PURPOSE: To provide a new alisol having a specific molecular structure, activating the activity of choline acetyltransferase, and useful for cerebral function-improving agents used for the therapy of Alzhemmer's disease, etc., severe amy...
|
|
JP07165788 |
PURPOSE: To obtain the subject novel compound which is obtained by allowing corticoid, corticosteroid or the like to undergo esterification with an activated carboxylic acid, has a strong topical or local anti-inflammatory activity and i...
|
|
JP07109295 |
PURPOSE: To obtain the glycoside, expressed by a specific formula, having excellent hair producing and growing effects and safety capable of sufficiently withstanding the use for a long period and useful as a hair producing and growing a...
|
|
JP07109293 |
PURPOSE: To obtain the glycoside, expressed by a specific formula, having excellent hair producing and growing effects and safety capable of sufficiently withstanding the use for a long period and useful as a hair producing and growing a...
|
|
JP07109286 |
PURPOSE: To obtain a novel derivative which is useful as an antiinflammatory agent of low toxicity because it has the inhibitory action against type III allergy. CONSTITUTION: A derivative of the formula I (R is monosaccharide, OHprotect...
|
|
JP07109294 |
PURPOSE: To obtain the glycoside, expressed by a specific formula, having excellent hair producing and growing effects and safety capable of sufficiently withstanding the use for a long period and useful as a hair producing and growing a...
|
|
JP07089982 |
PURPOSE: To obtain a corticosteroid 17-alkyl carbonate 21-[0]-carboxylic acid carbonic ester which has a very strong local and topical anti-inflammatory action and is effctive in treating inflammatory dermatosis by reacting a specific al...
|
|
JP07041496 |
PURPOSE: To provide a steroid derivative for preventing and treating diseases such as prostatic hypertrophy, prostatic cancer, etc., caused by excessive 5α- dihydrotestosterone, having excellent inhibitory action on testosterone 5α-red...
|
|
JP07033792 |
PURPOSE: To obtain a new glycosyl donor simply, in high yield and high selectivity by reacting an acyltetraalkylglycopyranoside with a trimethylsilyl ether of an alcohol in the presence of a catalytic amount of an acidic catalyst. CONSTI...
|
|
JP07017995 |
PURPOSE: To provide novel compounds having acceleration activity to produce prostaglandin I2, thrombolytic activity or the like and useful in the treatment and prevention of thrombosis or arteriosclerosis. CONSTITUTION: This pomol acid o...
|
|
JP06329695 |
PURPOSE: To provide the subject new compound having an activity to inhibit absorption of bile acid in the small intestine and useful as a lipid level lowering agent to lower the level of cholesterol and the like by reacting bile acid wit...
|
|
JP06329696 |
PURPOSE: To provide a new latctone compound composed of a 1α, 25- dihydroxyvitamin D3-based lactone compound, having a calcium concentration reduction effect, a tumor cell growth inhibitory effect and an osteogenesis promotion effect an...
|
|
JP06263785 |
PURPOSE: To obtain a stable new compound easy to prepare, capable of efficiently giving in a high yield glycoside compounds as useful for medicines, pesticides, etc., as an intermediate therefor, also capable of streoscopically controlli...
|
|
JP06256206 |
PURPOSE: To obtain an agent for lowering side effect of Plecotus auritus having cardiac action, comprising barrenwort, crude medicine widely used for the purpose of robustness and energy from ancient times or its essence as an active ing...
|
|
JP06234788 |
PURPOSE: To obtain a new compound useful for treating and preventing human or animal viral infections, especially infection with human immunodeficiency virus, cat immunodeficiency virus or the like. CONSTITUTION: The objective compound i...
|
|
JP06211893 |
PURPOSE: To provide the novel derivative exhibiting low toxicity and useful for remedy for diseases such as hear failure, hypertension or the like containing the derivative active on cardiovascular system. CONSTITUTION: By condensing a 1...
|
|
JP06192287 |
PURPOSE: To obtain new safe compounds having low toxicities and useful for treating cardiac and vascular diseases such as heart failure and hypertension. CONSTITUTION: There compounds of formula I [a wave line means that 17- positioned s...
|
|
JP06192286 |
PURPOSE: To obtain a new compound having an activity against the cardiovascular system and extremely low in toxicity and useful for treating cardiac and vascular diseases such as heart failure and hypertension. CONSTITUTION: This compoun...
|
|
JP06157586 |
PURPOSE: To provide novel compounds useful for treatment of cardiovascular disorders such as heart failure, hypertension, reducing toxicity and exhibiting affinity for receptor site of the Na+, K+-ATPase. CONSTITUTION: By reducing compou...
|
|
JP06094721 |
PURPOSE: To obtain a photochemical labeling reagent useful for genetic phatogonomy by adding a digoxigenin derivative, a spacer molecule, and a furocoumarin derivative to the reagent. CONSTITUTION: A labeling reagent expressed by a formu...
|
|
JP06065284 |
PURPOSE: To obtain the subject low-toxic new compd. useful as a therapeutic drug for cardiovascular diseases such as heart failure and hypertension. CONSTITUTION: This invention provides a compd. expressed by formula I or its salts, and ...
|
|
JP06056868 |
PURPOSE: To provide a process for the easy synthesis of a 2-deoxy-2amino sugar derivative in a high yield. CONSTITUTION: 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxy carbonylamino)-β-D-glucopyranoside or 1,3,4,6-tetra-O-acety...
|
|
JP06048946 |
PURPOSE: To provide a tonic agent which contains a saponin derivative and has an action reduce hemorrhage and can be effectively given on operation. CONSTITUTION: The tonic agent contains 20 (S)-protopanaxadiol-3-[β-D- glucopyranosyl (1...
|
|
JP06040920 |
PURPOSE: To provide a treating agent for viral infections containing CHIKUSETSU saponin III as an active ingredient. CONSTITUTION: The agent contains a kind of saponin in CHIKUSETSU GIN SENG (a plant in Araliaceae) which has been known t...
|
|
JP06025279 |
PURPOSE: To provide a cockroach-collecting pheromone comprising a cockroach- attracting substance and a cockroach-restraining substance and useful as a cockroach-controlling agent extremely excellent in its controlling effect because of ...
|
