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Matches 1 - 50 out of 1,352

Document Document Title
WO/2018/068021A1
The present invention relates generally to compositions and methods for treating cancer and hypercortisolism. Provided herein are substituted steroidal derivative compounds and pharmaceutical compositions comprising said compounds. The s...  
WO/2018/062904A1
Disclosed are a composition for production of ginsenoside compound K using a high temperature-β-glycosidase and a high temperature-α-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producin...  
WO/2018/028144A1
The present application provides a separation and purification method for high-purity mogroside V, comprising the following steps: (1) dissolving and centrifuging: taking a Siraitia grosvenorii crude product, and adding water for dissolv...  
WO/2018/013613A1
Described herein are neuroactive steroids or a pharmaceutically acceptable salt thereof. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a comp...  
WO/2018/002897A1
The present invention concerns compounds having formula (I) and compositions thereof with a pharmacologically acceptable excipient and uses thereof as a medicament, in particular for the treatment and/or prevention of a disorder selected...  
WO/2017/211079A1
The present application relates to a technique for extracting mogroside V. Provided is a method for extracting high-purity mogroside V from Siraitia grosvenorii. The specific steps comprise: pre-treatment of a raw material, extraction, c...  
WO/2017/199033A1
The invention relates to compounds of general formula (I): wherein: R1,R2, R3, R4, R5, R6 and Y are as defined herein. The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditio...  
WO/2017/199039A1
The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein. The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis...  
WO/2017/186135A1
Disclosed in the present invention are a compound and an application thereof for the treatment of cataracts. The structural formula of the compound is shown in formula I. The compound shown in formula I, a prodrug thereof, or a pharmaceu...  
WO/2017/150723A1
Algae that generates a sterol and a sterol production method that uses the algae. According to the present invention, a sterol is produced by culturing algae, such as strain AJ7867 (FERM BP-22304) and strains derived therefrom, that has ...  
WO/2017/111979A1
The present application relates to crystalline forms A, D, F, G and I of obeticholic acid. These crystalline forms are useful in the production of Obeticholic acid (in particular its purification), which is a drug useful for the treatmen...  
WO/2017/075257A3
Disclosed herein are compounds having structural Formula (I), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. Also disclosed are compositions comprising the present compounds and methods o...  
WO/2017/075257A2
Disclosed herein are compounds having structural Formula (I), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. Also disclosed are compositions comprising the present compounds and methods o...  
WO/2017/069565A1
The present invention relates to a method for selectively producing ginsenoside Rd, which is originally present in a trace amount in ginseng, from panaxadiol-based saponins in ginseng and, more specifically, to a method capable of obtain...  
WO/2017/069561A1
The present invention relates to a method for selectively producing ginsenoside F2, compound Mc, and compound O, which is originally present in ginseng in trace amounts, from saponins of ginseng and, more specifically, to a method capabl...  
WO/2017/069569A1
The present invention relates to a method for selectively producing compound K and compound Y, which are originally present in trace amounts in ginseng, from saponins of ginseng and, more specifically, to a method capable of obtaining de...  
WO/2017/057851A1
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...  
WO/2017/057852A1
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...  
WO/2017/044659A1
The present disclosure is directed to compositions, formulations and methods of use thereof in the treatment and prevention of ocular conditions including cataract and presbyopia.  
WO/2017/023694A1
This invention relates the use of Cortisol blockers (e.g., glucocorticoid receptor [GR] antagonists) for the treating or preventing viral infections, treating or preventing treatment resistant prostate cancer, treating or preventing neop...  
WO/2017/003124A1
The present invention relates to a method for screening a mitochondrial activity enhancer by using gypenoside-treated cells, to a composition, containing the gypenoside, for screening the mitochondrial activity enhancer, and to a kit com...  
WO/2016/164504A1
The invention provides bioconjugates of heterocylic compounds such as S-adenosylmethionine and S-adenosylhomocysteine with biotin or digoxigenin. The bioconjugates also include carbon and nitrogen linker moiteies of varying length that a...  
WO/2016/127543A1
Provided are a class of sucrose ester-type cationic lipoids and a preparation method therefor. A vector prepared by using the cationic lipoid can be used to deliver a nucleic acid. The sucrose ester-type cationic lipoid is prepared by us...  
WO/2016/107471A1
The present invention relates to a chemical and pharmaceutical technology, and in particular to a STAT3 and ERK signal pathway inhibitor and a use thereof. On the one hand, provided is a STAT3 and ERK signal pathway inhibitor. The inhibi...  
WO/2016/095249A1
Provided are a 20(R)-ginsenoside Rg3 multiacylated derivative, as represented by the formula (I), and a preparation method and antitumor application of same. R=CH3(CH2)nCO, and n=0 to 5.  
WO/2016/095248A1
The present invention provides a 20(R)-ginsenoside Rg3 derivative, as represented by the formula (I), and a preparation method and antitumor application of same. R1=H, R2=CnH2n+1CO or R1=CnH2n+1CO, R2=H or R1=R2=CnH2n+1CO, and n=3 to 30.  
WO/2016/090139A1
Described herein are compositions and methods for hormone replacement therapy that address the shortcomings of the existing methods. Described herein are pharmaceutically effective partial agonistic antiprogestins. The combined applicati...  
WO/2016/082789A1
Described herein are neuroactive steroids of the Formula (II) : or a pharmaceutically acceptable salt thereof; wherein A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6 and ----- are as defined herein. Such compounds are envisioned, in certain...  
WO/2015/177469A1
The present invention relates to chemical compounds and the therapeutic use thereof, in particular for improving muscular quality in mammals. More particularly, the invention enables improvement of muscular quality in sarcopenic mammals ...  
WO/2015/168779A1
A method for purifying Mogroside V comprises passing a solution of a pre-prepared Siraitia grosvenori primary extract through a multi-column system including a plurality of columns, in series, packed with a porous adsorbent resin to prov...  
WO/2015/171555A1
Disclosed is a steviol glycoside referred to as rebaudioside D2. Rebaudioside D2 has five β-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D2, a UDP-glycosyltransferase fusion e...  
WO/2015/081778A1
The present invention belongs to the field of organic synthesis, relates to a method for synthesizing a saponin, and in particular, to a method for constructing a glycosidic bond in a saponin, and comprises the following steps: directly ...  
WO/2015/082012A1
Suggested are triterpene-glycoside compounds, which are obtainable by the extraction of Momordica grosvenorii (Siraitia grosvenori) which are useful as a sweetener or sweetener enhancer in preparations and compositions, especially oral e...  
WO/2015/062556A1
Use of a composition comprising plant based saponins for regulating and balancing gut microflora in a subject.  
WO/2014/194068A1
Compounds which are glycosylates of an A-ring of a cardiotonic steroid, wherein the steroid is attached to the anomeric position of (a) a monosaccharide comprising a C-4 amino group, or (b) an oligosaccharide are provided.  
WO/2014/189351A3
The present invention describes a process to obtain the compound 6-0-palmitoyl-3-beta-D-glucopyranosyl-campesterol (6-O-PGC) from Lopezia racemosa extracts. The procedure to prepare extracts and fractions from Lopezia racemosa wild plant...  
WO/2014/189351A2
The invention relates to the method for producing the compound 6-0-palmitoyl-3-0-β-P-D-glucopyranosyl-campesterol(6-O-PGC) with a novel structure and with in vivo anti-inflammatory activity, from plant extracts obtained from in vitro c...  
WO/2014/150127A1
Fruit extracts containing mogrol glycosides substituted with five or more sugar residues per molecule such as mogroside V may be treated with acid or enzymes to increase the content of mogrol glycosides such as siamenoside I and mogrosid...  
WO/2014/146089A2
Novel mogrosides and methods for heir purification are provided herein. In addition, compositions comprising said novel mogrosides and methods for preparing the same are provided.  
WO/2014/146089A3
Novel mogrosides and methods for heir purification are provided herein. In addition, compositions comprising said novel mogrosides and methods for preparing the same are provided. The present invention relates generally to novel mogrosid...  
WO/2013/149570A1
Provided are several types of ginsenoside polymorphic substances and a method for preparing same. In particular, new crystal form A, crystal form B, crystal form C, crystal form E, crystal form F, crystal form I, crystal form K, crystal ...  
WO/2013/149571A1
Provided are ginsenoside C-K polymorphic forms and a method for preparing same. The ginsenoside C-K polymorphic forms are crystal form D and crystal form H.  
WO/2013/143494A1
Disclosed is a protopanaxatriol ginsenoside preparation method, comprising the following steps: (a) protecting the hydroxyl of the protopanaxatriol, exposing a 20-position hydroxyl and at least one of 3-position, 6-position and 12-positi...  
WO/2013/100712A1
The present invention relates to a novel blocker for vascular leakage. The novel blocker for vascular leakage of the present invention inhibits the apoptosis of endothelial cells, suppresses the formation of actin stress fibers induced b...  
WO/2013/040441A1
The invention relates to a drug conjugate including a drug and a plant steroid. The drug conjugate may target the drug for intestinal cell delivery, and thus may be used to treat diseases, including intestinal diseases, or to affect inte...  
WO/2012/127176A1
The present invention relates to novel neurosteroids, especially derivatives of allopregnanolone and of epiallopregnanolone of formula (I) and the uses thereof as medicament for the treatment of neuropathologies, in particular neuropathi...  
WO/2012/100018A1
Stabilized benzyl phosphonic acid and naphthyl phosphonic acid analog compounds are effective in inhibiting the activity of autotaxin.  
WO/2012/079275A1
Provided is a method for preparing fluticasone furoate (fluoromethyl 6α,9α-difluoro-11β-hydroxy-16a-methyl-17α-[(2-furoyl)oxy ]-3-one androsta-1,4-diene-17β-thiocarboxylate) represented by Formula I. The method comprises: 1) forming...  
WO/2012/068832A1
Provided is a method for preparing mogroside IV, which comprises hydrolyzing mogroside V, Momordica grosvenori fruits, or extracts of Momordica grosvenori fruits containing mogroside V with β-glucosidase. The content of mogroside IV in ...  
WO/2012/027957A1
Bufalin derivatives of formula I and the pharmaceutical compositions thereof are provided, wherein the radicals have the meanings as defined in the invention. The use of these derivatives is also provided.  

Matches 1 - 50 out of 1,352