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Matches 101 - 150 out of 500

Document Document Title
WO/2000/032177A2
The invention provides the use of 17-ketosteroid compounds, as well as derivatives, metabolites and precursors of such compounds, and pharmaceutically acceptable salts of any of these compounds, collectively defined herein as the 'compou...  
WO/2000/032201A2
The invention provides the use of 17-ketosteroid compounds, as well as derivatives, metabolites and precursors of such compounds, and pharmaceutically acceptable salts of any of these compounds, collectively defined herein as the 'compou...  
WO/2000/032176A2
The invention provides the use of 17-ketosteroid compounds, e.g., 16$g(a)-bromoepiandrosterone, as well as derivatives, metabolites and precursors of such compounds, and pharmaceutically acceptable salts of any of these compounds, collec...  
WO/1999/032127A1
Compositions of angiostatic agents for treating GLC1A glaucoma and methods for their use are disclosed.  
WO/1999/025359A1
The invention provides a process for the sterilization of a powdered form of a glucocorticosteroid, sterile glucocorticosteroids, sterile formulations containing glucocorticosteroids and use thereof in the treatment of an allergic and/or...  
WO1999001467A3
There are described therapeutically active compounds or salts or solvates thereof, hydrolysable in human or animal blood to compounds with reduced therapeutic activity. There is also described a method of identifying a compound capable o...  
WO/1999/003503A1
Methods for treating ocular neovascularization using photodynamic therapy in combination with an angiostatic steroid are disclosed.  
WO/1999/001467A2
There are described therapeutically active compounds or salts or solvates thereof, hydrolysable in human or animal blood to compounds with reduced therapeutic activity. There is also described a method of identifying a compound capable o...  
WO/1998/055498A1
The invention relates to 17$g(b)-allyloxy(thio)alkyl-androstane derivatives having general formula (I) wherein R�1? is (H, OR), (H, OSO�3?H) or NOR; with R being H, (C�1-6?)alkyl or (C�1-6?)acyl; each of R�2? and R�3? is inde...  
WO1998018429A3  
WO/1998/032718A1
The properties of biologically active compounds, for example drugs and agrochemicals, which contain in their molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, carboxylic acid and...  
WO/1998/018429A2
A method of lowering plasma levels of Lp(a) or inhibiting the generation of apo(a) in a human by administering an effective amount of a compound of formula (I) wherein: R?1� is hydrogen or alkyl; A, B, D, E, G, R?2� and R?3� each a...  
WO/1998/014194A1
The invention relates to a method of alleviating the symptoms of anxiety. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The st...  
WO/1998/009935A1
A process for preparing a compound having structure (I) wherein n is an integer from 1-5; each of R�1? and R�2? independently is optionally substituted C�1?-C�6? alkyl; each of W and X is independently hydrogen or C�1?-C�6? a...  
WO/1998/003207A1
The invention relates to a method of alleviating the symptoms of PMS and anxiety. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor...  
WO/1998/002450A2
Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have...  
WO/1997/042214A1
The invention provides new androstene derivatives having anti-inflammatory activity, pharmaceutical compositions containing them, and methods of administering them to warm-blooded animals in the treatment of inflammation. The active comp...  
WO/1997/024365A1
Compounds of the androstane series are described having general formula (I) and solvates thereof, in which R1 represents O, S or NH; R2 individually represents OC(=O)C1-6 alkyl; R3 individually represents hydrogen, methyl (which may be i...  
WO/1997/001346A1
A cosmetic or pharmaceutical and particularly dermatological composition including, as the active ingredient, an extract of plants of genus Filicium, and particularly an extract of plants of species Filicium decipiens, preferably in an a...  
WO/1996/011939A1
A process for providing novel compounds of formula (I), that are useful as 6-azaadrostenone testosterone 5-alpha-reductase inhibitors, from commercially available compounds of formula (II) wherein, R1 and R2 represent: i) indepedently H ...  
WO/1996/011206A1
The disclosed invention is a process for preparing 17-beta-substituted-androsta-3,5-dien-3-carboxylic acids from 3-halo-17-beta-substituted-androsta-3,5-dienes. The process may be performed in either of two ways: (1) the 3-halo compound ...  
WO/1996/010032A1
The invention relates to estrene steroid, which bind to neuroepithelial receptors. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. The figure...  
WO/1996/010031A1
The invention relates to novel, androstane steroids which are the ligand semiochemicals which bind to neuroepithelial receptors.  
WO/1996/003422A1
The present invention provides compounds of formula (I) wherein the symbol --- represents a single or a double bond; R is a hydrogen atom or a C1-C4 alkyl group; A is a single bond or a straight or branched C1-C6 alkylene chain; B is a s...  
WO/1996/003420A1
The present invention provides a compound of formula (I), wherein A is a bond or a straight or branched C1-C6 alkylene chain; W is a group -R1, -OR2, -NR3R4 or (a) wherein: Y is oxygen or sulphur; R1, R2 and R4 are: a C1-C10 alkyl group,...  
WO/1996/000230A1
The present invention relates to a process for the preparation and manufacture of 3-amino-substituted glycosylated bile acid derivatives. Novel intermediates and related compounds are also disclosed. In particular, the present invention ...  
WO/1995/033761A1
Invented are 17 'alpha' and 17 'beta'-substituted aromatic A ring steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-'alpha'-reductase.  
WO/1995/029186A1
The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglyco...  
WO/1995/028413A1
Invented are 17'beta'-substituted 3-carboxy steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-'alpha'-reductase.  
WO/1995/008557A1
The present invention relates to oligosaccharide-containing 14-aminosteroid compounds and the pharmaceutically-acceptable acid salts or esters thereof of general formula (I), wherein: a) R1 is (i) COOR5, where R5 is hydrogen, a 1-6 carbo...  
WO/1995/007926A1
The present invention relates to compounds of formula (I), wherein carbons 1 and 2 are joined by either a single or a double bond; R1 is hydrogen or methyl; R2 is hydrogen or methyl; R3 is (A) or (B) wherein X, W, Z, R4, R5, R6, R7 and R...  
WO/1995/007927A1
The present invention relates to the compound of formula (I), also known as 17'beta'-N-(2,5-bis(Trifluoromethyl))phenylcarbamoyl-4-aza-5 'alpha'-androst-1-en-3-one, solvates thereof, its preparation, intermediates used in its preparation...  
WO/1995/004535A1
The application discloses methods of making medicaments for treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural ...  
WO/1994/026725A1
Lupane derivatives of general formula (I) in which R is: (II), wherein X is a bond or an optionally substituted carbamoyl or aminocarbonyl, Y is a bond or phenylene, R� and R��, which are the same or different, are H or methyl and ...  
WO/1994/026695A1
Lupane derivatives of general formula (I) in which R is a radical of general formula (II) for which R' is a hydrogen atom or an alkyl radical, X is carbamoyl, N-m�thyl carbamoyl, aminocarbonyl or N-methylaminocarbonyl, Y is substituted...  
WO1994014833A3  
WO/1994/014833A2
The present invention relates to certain substituted 17beta-substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I), wherein R1 and R2 i) are independently hydrogen or lower alkyl and the bond between the carbons bearing R1 and R2 i...  
WO/1994/014834A1
Steroids of formula (I) where -_-_-_-_ is independently at each of the 1,2-, 4,5- and 6,7-positions, a single or double bond; R1 is a straight- or branched-chain C1-4 alkyl or C2-4 alkenyl; R2 is hydrogen or methyl; R3 is C1-7 alkyl, phe...  
WO/1994/013690A1
Steroids of formula (I) where --- is a single or double bond; R1 is hydrogen or fluorine; and R2 is propyl or trans-prop-1-enyl, and racemic mixtures and diastereoisomers thereof, processes for their preparation, pharmaceutical compositi...  
WO/1994/011385A1
Invented are novel 17alpha-acyl steroidal 5alpha-reductase inhibiting compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-alpha-reductase. Also invented are novel ...  
WO/1994/011386A1
Invented are 17alpha and 17beta-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-alpha-red...  
WO/1994/011004A1
Invented are 17alpha and 17beta-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-alpha-red...  
WO1993025568A3  
WO/1994/000125A1
Invented are 17alpha and 17beta-alkylketone-3-carboxy aromatic A ring analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-alpha-re...  
WO/1993/025568A2
Novel antihypercholesterolemic agents are provided. An exemplary group of compounds has structural formula (I), wherein R is a C-17 side chain, R?1¿ is -OH, =O, or the like, R?8¿ and R?9¿ are independently hydrogen or lower alkyl, and...  
WO/1993/022333A1
Invented are 17$g(a) and 17$g(b)-substituted acyl-3-carboxy aromatic A ring analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-$g...  
WO/1993/018053A1
This invention provides a simplified method for converting pregnan-3,20-dione compounds to 3alpha-hydroxy,3beta-substituted-pregnanes. By selective use of reagents the unprotected dione is converted chemoselectively and diastereoselectiv...  
WO1993010141A3  
WO/1993/016098A1
Invented is an improved process for the preparation of substituted steroidal dienes.  
WO/1993/016097A1
Invented is an improved process for the preparation of substituted steroidal dienes. Also invented are novel intermediates used in said process.  

Matches 101 - 150 out of 500