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JP2005508866A |
The composite for eyes containing the medicine for eyes, for example, ケトチフェン, and a straight-chain-shape polysaccharide compound, for example, a hyaluronic acid compound, is useful to 1 1-time partial medication to eyes. [per...
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JP2005060402A |
To provide an advantageous production method of a compound which can serve as an intermediate of a vitamin D derivative.In the method, a compound of formula (3) (wherein R12 and R13 are each a protecting group; and R15 is an alkyl group,...
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JP2005506321A |
It is useful for the medical treatment of the protection from its 3* ヒドロキシ *7* ヒドロキシ steroid, 3* oxo *7* ヒドロキシ steroid (especially the 7beta isomer), and ischemia [pharmacologically as opposed to circumferen...
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JP2005504762A |
17 and/or 21 ester and these production methods of alpha [which shows remarkable anti-male hormone activity / 17], and 21* dihydroキシプ regna *4, 9*ジエン*3, 20* Xeon and alpha [17], and 21* dihydroキシプ regna *4*エン*3, and...
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JP2005504776A |
The present invention relates to use, its composite, and kit of the pregnane in guidance of painkilling [in a mammal / it is desirable and] to a neuropathic pain without evident sedation.
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JP2005503383A |
Discharge by which, as for the present invention, the medical treatment agent, for example, the manufacture thing of steroid, was controlled; it is related with use of this tablet for treating those illnesses like the illness which will ...
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JP2004538294A |
the present invention -- a 6alpha* full オロプ leg -- nan -- the line in a (I) [type and between the 1st place and the 2nd place expresses a single bond or a double bond, and; R, An OH, OCOR, X, SOR, or (R) (R) (R) SiO* machine is exp...
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JP2004536088A |
The present invention beta [11] and 17alpha* dihydroxy *6alpha* メチルプ regna *1, 4*ジエン*3, 11beta, 17alpha of 20* Xeon 17* acetate (III), It is a new process for 21* トリヒドロキシ *6alpha* メチルプ regna *1, 4*ジ...
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JP2004535805A |
The present invention, 17alpha* ヒドロキシ *6alpha* methyl プレグン*4*エン*3, 20* Xeon They arebeta [11], alpha [17], and 21* トリヒドロキシ *6alpha* メチルプ regna *1, 4*ジエン*3, and 20* Xeon about 17* acetate ...
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JP2004534795A |
Full メタゾン (a [6], 9a*ジフルオロ*11beta, a [17], and 21* トリヒドロキシ *16a* methyl *プレグナ*1, 4*ジエン*3, 20* Xeon), How to be the method of preparing full メタゾン 21* acetate or its 17* carboxyl Andros...
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JP2004528364A |
When the present invention medicates a vomeronasal organ official with a 17* methylene Andros Than *3alpha* all analog, it offers especially that it is useful as an anti-depression medicine as a corticotropin releasing hormone (CRH) inhi...
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JP3549125B2 |
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JP2004516303A |
This invention relates to the medicine tablet containing the solid dispersing element, its manufacturing process, and this dispersing element of a nitrate active ingredient in at least one polymer chosen from the group which consists of ...
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JP2004514649A |
The synovial membrane CRH functions in the Parakou Lynn style which is abundantly revealed in the inflammatory cell of both rheumatoid arthritis and psoriatic arthritis synovial membrane and which guides core transcription factor NURR1. ...
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JP2004513749A |
The method of sterilizing the medicine composite containing the suspension of a medicine includes the process of heating this medicine composite quickly from ambient air temperature to high temperature, and the process of cooling quickly...
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JP2004137196A |
To obtain an emulsifying agent which has excellently emulsifying action and is highly safe to organisms due to low toxicity and low skin irritation, or the like, has excellent adhesivity to the skin and sense of use and is especially sui...
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JP2004512359A |
The present invention relates to these use for treating the condition of the new medicine composites which use the anti-Kolin action medicine and corticosteroid as a base, these production methods, and the respiratory system.
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JPWO2002051422A1 |
本発明は、下記式（１）：〔式中、Ｒは水素
原子、ハロゲン原子、水酸基又は基−ＯＣＯ
Ｒ１（ここでＲ１はハロゲン原子若しくはシ
クロアルキル基が置換することのある直...
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JP2004511445A |
It is a unit dosage tablet and other corticosteroid of the amount of potency, such as less than 2.5 mg of prednisolone or equivalence, is contained. For the medical treatment of rheumatoid arthritis, the once-daily treatment of the unit ...
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JP3535555B2 |
PURPOSE: To obtain compounds used for anti-inflammatory or the like with high efficiency by, after treating specific steroid derivatives with a methylating agent in the presence of a copper-based catalyst, hydrolyzing the formed 16α- me...
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JP2004504403A |
The present invention relates to a process for the preparation of a compound of formula (I) which comprises the following step: wherein step (a) comprises oxidation of a solution containing the compound of formula (II) wherein the soluti...
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JP2004504333A |
the present invention -- a -- at least one antifungal and b -- it being a composite containing at least one tunic formation agent, and, The ingredient b is related with the use as nail polish of the composite which is a chitosan derivati...
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JP3492717B2 |
PURPOSE: To efficiently obtain the compd. useful for an intermediate of medicines or the like at high yield by bringing a compd. obtd. by oxidizing a specified compd. in the presence of water to solvolysis reaction in an acidic medium or...
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JP2003530301A |
(57) Summary book invention relates to the use at the time of dealing with the new organism disease containing the virus which annihilates the new organism cell which can reproduce and has a deficit in an IFN mediation antivirus response...
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JP2003529604A |
(57) Especially summary book invention relates to the compound which has general formula (I). The compound of the formula I to provide in addition, the present invention, the method of using the compound of the formula I advantageously -...
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JP2003528137A |
(57) Summary book invention makes the special feature to the method of dealing with or preventing a progestin dependence state in a 験-ed object with the disposal of the method of checking the progestin activity in the 験-ed object whi...
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JP3445271B2 |
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JP3466645B2 |
PURPOSE: To obtain the compd. free from by-products at high yield by using specified halohydrin as a starting raw material and bringing this to react under specified conditions. CONSTITUTION: Halohydrin of formula I (X is chlorine or the...
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JP2003517472A |
(57) Summary book invention relates to 3* methylene steroid derivative which has a general formula (1) for treating an arthritis disease and/or an autoimmune disease, or its prodrug. Among type, when beta* EPO キシド is formed togethe...
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JP3418428B2 |
PURPOSE: To provide the novel steroid compounds whose steroid skeleton is bound at carbon atom 17 to a spiromethylene ring having progestational activity and antiprogenstational activities, and useful as contraceptive medicines. CONSTITU...
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JP2003510277A |
(57) Summary book invention Inflammatory bowel disease (chronic ulcerative colitis, Crohn's disease, and rectitis), other noninfectious alimentary canal inflammation (microscopic colitis and allergic eosinophilic gastroenteritis --) The ...
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JP3378245B2 |
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JP3356525B2 |
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JP2002356425A |
To provide a nonsurgical treatment for treating anal fissure and/or hemorrhoid or other benign anal diseases. The single nifedipine which is a calcium channel inhibitor, or a selective combination thereof with bethanechol is topically ap...
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JP2002356431A |
To provide a therapeutic agent for retinochroidal diseases containing a steroid having excellent effect than a conventional steroid as the active ingredient and a dosage form for treating retina and choroid diseases whereby steroid can b...
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JP2002356422A |
To provide a nonsurgical cure or treatment for treating anal fissure and/or hemorrhoid or other benign anal diseases. Bethanechol of a choline agonist is topically applied to the anus to treat the benign anal diseases, especially the ana...
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JP3352095B2 |
Bethanechol is administered locally to the anus for the treatment of benign anal disorders, in particular anal fissures and haemorrhoids. It induces a reduction in the mean and resting pressure, thereby assisting in the healing of anal f...
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JP3349554B2 |
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JP2002539135A |
(57) Summary book invention relates to the knowledge which the natural steroid for using it as the androgen, i. E. , the steroid characterized by arrangement with opposite 14alpha and 17beta, does not expect. The steroid of the present i...
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JP2002539135A5 |
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JP2002322168A |
To provide pharmaceutical compounds which reduce undesirable effects occurred at the region where is apart from the target site.Pharmaceutical compounds represented by general formula (I) or their salts or solvates, which are effective i...
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JP2002308776A |
To provide a medicinal composition useful in the therapy for human prostatic adenocarcinoma.The medical composition for treating human prostatic adenocarcinoma contains a 5-α-reductase inhibiting compound such as 17β-(N-t- butylcarboxy...
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JP3328729B2 |
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JP2002529238A |
(57) Summary book invention offers the new method of mainly collecting organic solutes from solution in one mode. A solute and the adsorbent held at the supporting structure are contacted, and, thereby, a solute is made to stick to a mat...
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JP2002527448A |
(57) summary book invention, The salt permitted on 21-triol, useful as progesterone agent 5alpha-pregnanebeta 3 and 20S and 20-O-beta-glucuronide and the 5alpha-pregnane 3 beta, 20R-ジオール and 20-O-beta-glucuronides, and those medi...
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JP2002527525A |
(57) Summary book invention relates to the production method of the high purity composite ofalpha 7 and (alpha 17) *17* ヒドロキシ *7* methyl *19* Knoll *17* プレグヌ *5 (10) * エン *20* in *3* ON. By the above-mentioned metho...
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JP2002201199A |
To provide a process for efficiently preparing a pregnane derivative useful as an intermediate or the like for synthesizing squaramine from an easily available raw material in a short step.This process for the preparation of the 21-hydro...
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JP3328377B2 |
PURPOSE: To economically obtain the subject compd. showing therapeutic activity without producing by-products by a new method of inverting a specified starting compd. into a halohydrin, rearranging the halohydrin in the presence of an al...
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JP3292928B2 |
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JP2002155097A |
To convert a 6β-fluorosteroid into a corresponding pharmacologically active 6α-fluoro derivative without requiring vigorous reaction conditions.This method for isomerizing a 6β-fluoro derivative into a corresponding 6α-fluoro derivat...
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