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Matches 351 - 400 out of 1,314

Document Document Title
JP2010059181A
To provide an improved formulation which, in systems to imitate inhalation, achieves an improved dispersion of the drug.A dry powder composition has a poured bulk density of 0.28-0.38 g/ml and includes one or more potent pharmaceutically...  
JP2010506140A
In various aspects, the present teachings provide labeling reagents and sets of labeling reagents for the relative quantitation, absolute quantitation, or both, of hydroxylated compounds including, but not limited to, hydroxylated ring c...  
JP4417838B2  
JP2010503722A
The present invention relates to crystalline ciclesonide methanol solvate Form C, processes for its preparation, its use in the synthesis of crystalline ciclesonide Form A and its use in medicine.  
JP2010013482A
To provide a medicine for treating multiple myeloma.The medicine for treating multiple myeloma in a patient includes cyclopropane carboxylic acid {2-[(1S)-1-(3-ethoxy-4-methoxy-phenyl)-2-methane sulfonyl-ethyl]-3-oxo-2,3-dihydro-1H-iso-i...  
JP2009545546A
The present invention refers to the treatment of a rheumatic disease and/or osteoarthritis by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof.  
JP2009280583A
To provide a method for improving the actions of many biologically active compounds such as drugs and agrochemicals by a chemical derivatization method.The properties of biologically active compounds such as drugs and agrochemicals conta...  
JP2009539964A
Anti-pro ゲストーゲン with the strong present inventionAnd it is related with the new industrial process for composition without the solvent sum of 17of formula (I) which is anti-glucocorticoid agent alpha* acetoxy *11beta* [4* (N ...  
JP4368945B2  
JP4361976B2  
JP4354809B2
17α,21-Dihydroxypregna-4,9-diene-3,20-dione and 17α,21-dihydroxypregna-4-ene-3,20-dione 17 and/or 21 esters of having remarkable antiandrogenic activity, and the processes for the preparation thereof.  
JP2009535017A
A process for enantioselective enzymatic reduction of an oxo steroid compound which includes the following steroid structure (ABCD) which has at least one oxo group in a steroid skeleton, An oxo steroid compound is returned with hydroxy ...  
JP2009191072A
To provide a method for treating and preventing certain types of cancers, including primary and metastatic cancers, as well as cancers that are refractory or resistant to conventional chemotherapy.Provided is the method of preventing or ...  
JP2009173683A
To provide a method for treating and preventing a cancer of a particular type, for example, a primary cancer, a metastatic cancer and a cancer unfit or resistant to conventional chemotherapy.The medicine for treating or preventing a mult...  
JP2009167188A
To provide a new compound having a specific strong progesterone-like property and devoid of residual androgenic activity.The compound is expressed by formula (I), wherein R1, R2, R3, R4, R5 and R6 are each a hydrogen atom or a specific s...  
JP2009521511A
A method of high intraocular pressure regulation by prescribing acetic acid アネコルタブ for the patient by a part of filtration 胞手術 is indicated. The present invention includes a method of dealing with glaucoma, between glau...  
JP4260886B2  
JP2009511604A
(i) The method and constituent for controlling primary opening 隅角 glaucoma (POAG), the glaucoma of the form of (ii) others, or the high intraocular pressure relevant to (iii) glucocorticoid medical treatment are indicated. This metho...  
JP2009511632A
Ophthalmically therapeutic materials, such as liquid-containing compositions and polymeric drug delivery systems, include a therapeutic component that includes an Glucocorticoid Derivative which, upon delivery to the posterior segment of...  
JP2009046472A
To provide an emulsified composition having effects of inhibiting adhesion of Staphylococcus aureus to the skin and maintaining humidity, and useful for treating, preventing or improving symptoms caused by dry skin and/or diseases expres...  
JP4233504B2
The object of the present invention is to provide vitamin D derivatives that have excellent physiological activities as medicines, particularly as therapeutic agents for skin diseases such as psoriasis, and that have a reduced hypercalce...  
JP2009507879A
9 as 剤 for the present invention to check secretion of gonadotrophic hormone, C of 11* デヒドロコルテキソロン3*C10It is related with use of 17alpha* ester. Therefore, 9 for the manufacture of medicine for the medical treatme...  
JPWO2009022477A
[Subject] Provide the high molecular weight polymer uniformly distributed by high density in the physiologically active substance. [Means for Solution] The above-mentioned subject has been solved by choosing and using poly norbornene for...  
JP4213205B2  
JP4170751B2  
JP4150846B2  
JP4145350B2  
JP2008525317A
Whether there is any antagonism to a gamma * aminobutyric acid (A) receptor (GABA*A) by showing a blocking action of 3 alpha * ヒドロキシ *5 alpha / beta * steroid, and partial antagonism [as opposed to / do not crawl again, but len...  
JP4095018B2  
JP2008120839A
To provide a compound useful for treating mammalian diseases characterized by undesired cell mitosis.A new estradiol derivative binds to tubulin, inhibits microtubule formation or exhibits anti-mitotic properties.  
JP2008120840A
To provide a compound useful for treating mammalian diseases characterized by undesired cell mitosis.A new estradiol derivative binds to tubulin, inhibits microtubule formation or exhibits anti-mitotic properties.  
JP4070463B2  
JP4066272B2  
JP2008044957A
To provide a good antifungal nail varnish composition able to be easily formulated, prepared and preserved.The composition comprises (a) at least one antimycotic agent and (b) at least one film-forming agent wherein the component (b) is ...  
JPWO2005095434A1
本発明は、一般式(I)で示されるプレグナ ン誘導体に、プロトン供給体、アミンおよび /またはアンモニアの存在下、アルカリ金属 およびアルカリ土類金属から選ばれる金...  
JPWO2005095432A1
本発明は、一般式(I)および一般式(II )で示される5α−プレグナン誘導体の混合 中の一般式(II)で示される5α−プレ ナン誘導体の炭素−炭素二重結合を選...  
JPWO2005095431A1
本発明は、一般式(I)で示されるプレグナ ン誘導体に、プロトン供給体、アミンおよび /またはアンモニアの存在下、アルカリ金属 およびアルカリ土類金属から選ばれる金...  
JPWO2005095433A1
本発明は、一般式(I)で示されるプレグナ ン誘導体に、プロトン供給体、アミンおよび /またはアンモニアの存在下、アルカリ金属 およびアルカリ土類金属から選ばれる金...  
JP2008504232A
In this specification, the composites which deal with the new angiogensis of the choroid coat resulting from the externally caused injury to an operation of an eye or ocular tissue, and those directions for use are indicated. The blood v...  
JP4048114B2  
JP4039683B2  
JP2007538089A
The method for sterilization of the substitution activity グルコ corticosteroid which includes heat-treating the substitution activity グルコ corticosteroid of the form of suspension by time 湿熱 effective in sterilization by the...  
JP4008024B2  
JP2007527364A
The sterilization method of a non-water solubility solid medicine substance is indicated. This method offers sterilization of the suitable medicine substance for 経肺 medication. Especially this method is used for the industrial plant ...  
JP2007527381A
The present invention relates to the new procedure for production of the small crystalline particles of the 狭 size distribution of high yield.  
JP3983796B2  
JP2007231020A
To provide a new compound which improves the lipid barrier penetrability of a biologically active substance comprising a fatty acid such as lipoic acid and simultaneously makes a biologically active substance comprising a different fatty...  
JP3960481B2  
JP2007153910A
To provide a therapeutic method effective for nail mycosis, and to provide a therapeutic preparation.The present invention relates to a composition comprising (a) at least one antimycotic agent and (b) at least one film forming agent, wh...  
JP3918119B2
PCT No. PCT/EP94/00092 Sec. 371 Date Jun. 14, 1995 Sec. 102(e) Date Jun. 14, 1995 PCT Filed Jan. 12, 1994 PCT Pub. No. WO94/16710 PCT Pub. Date Aug. 4, 1994The present invention relates to a topical oil-in-water emulsion composition comp...  

Matches 351 - 400 out of 1,314