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Matches 101 - 150 out of 375

Document Document Title
WO/2005/092912
The subject invention provides a compound according to Formula I, wherein Formula (1) is O, NOH, NO(1-4C)alkyl, NO(1-4C)acyl; Al-A5 are C, substituted with RI, or N, provided that at least one and not more than three of Al-A5 are N; or o...  
WO/2005/090380
Salts of 3-O-(3',3'-dimethylsuccinyl)Betulinic acid (DSB) are disclosed. Particularly, the preparation, pharmaceutical evaluation, and in vivo bioavailability evaluation of N-methyl-D-glucamine and alkali metal salt forms of DSB are disc...  
WO/2005/077968
The present invention relates to novel compounds which are 7alpha-substituted 17-alkylene-16 alpha-hydroxy steroidal estrogens (see formula I). This invention specifically relates to estrogen derivatives which contain 7 alpha -substituen...  
WO/2005/077968
The present invention relates to novel compounds which are 7alpha-substituted 17-alkylene-16 alpha-hydroxy steroidal estrogens (see formula I). This invention specifically relates to estrogen derivatives which contain 7 alpha -substituen...  
WO/2005/044837
The conjugates of a hydrophilic polymer-Buxus's extracts or its derivatives were prepared by modifying Buxus's extracts such as cyclovirobuxine D and the like with said hydrophilic polymer such as polyglycol. With these conjugates, the p...  
WO/2005/042422
An optical fiber, and a method of making such optical fiber, wherein the optical fiber exhibits a beatlength greater than about 0.5 meters, and the fiber is spun to provide a polarization mode dispersion in the spun state of said fiber w...  
WO/2005/030790
The present invention relates to novel synthetic derivatives of triterpenes and the use of such derivatives as pharmaceuticals. In some embodiments, the present invention is directed to the use of derivatives of triterpenes of the presen...  
WO/2005/007669
The present Invention relates to novel fusidic acid derivatives of general formula (I) wherein X represents halogen, trifluoromethyl, cyano, azido, alkyl, alkenyl or aryl, wherein. said alkyl, alkenyl or aryl are optionally substituted b...  
WO/2005/002496
The invention relates to a method of obtaining taxosteroids and the precursors thereof from hydrindane bicyclic systems. According to the invention, the compounds have a tetracyclic system which combines the structural characteristics of...  
WO/2005/000869
Novel pentacyclic steroids and pentacyclic D-homosteroids comprising: (i) the tetracyclic steroid ring system or tetracyclic D-homosteroid ring system, respectively; (ii) a C(3) substituent selected from the group consisting of (a) a hyd...  
WO/2004/075831
A novel method is provided to measure 11β-hydroxysteroid dehydrogenase activity in intact whole animal tissues in the presence of systemically or ex vivo administered inhibitors of the enzyme. Inhibitors of the type 1 isoform (11β -HSD...  
WO/2004/072092
The invention relates to novel derivatives of betulinic acid with increased activity for the treatment of carcinomas and HIV diseases, to a method for producing novel betulinic acid derivatives of this type and to their use as medicaments.  
WO/2004/055040
The present invention relates to a simple and new single pot process for the preparation of oryzanol from the oryzanol enriched saponifiable fraction of rice bran oil (RBO) soapstock.  
WO/2004/028455
Betulin and dihydrobetulin acyl derivatives according to the present invention have been found to have potent anti-HIV activity. The compounds of the present invention have Formula I as described herein, or pharmaceutically acceptable sa...  
WO/2003/092578
The present invention relates to improved methods for synthesising cyproterone acetate (17&agr -Acetoxy-6-chloro-1&agr , 2&agr -methylene-4,6-pregnadiene-3,20-dione) from solasodine. The methods of the invention are shorter as those of t...  
WO/2003/080778
This invention relates to methods for treating distillates obtained during the process of deodorizing various oils. More particularly, this invention relates to methods for recovering fatty acids, tocopherols, and sterols from a distilla...  
WO/2003/066656
There is provided a crystalline complex comprising a compound of formula (I) in which the crystal lattice is stabilised by the presence of a guest molecule, characterised in that the crystalline complex is of space group P212121 having u...  
WO/2003/066032
There is provided a pharmaceutical aerosol formulation comprising (i) a compound of formula (I) or a solvate thereof as medicament, (ii) a liquified hydrofluoroalkane (HFA) gas as propellant; and characterised in that the compound of for...  
WO/2003/066026
There is provided according to the invention a pharmaceutical formulation comprising an aqueous carrier liquid having dissolved therein: (a) a glucocorticoid of formula (I), wherein R represents ethyl or a 5 membered heterocyclic aromati...  
WO/2003/066024
There is provided a pharmaceutical formulation comprising an aqueous suspension of particulate compound of formula (I) or a solvate thereof.  
WO/2003/066036
According to one aspect of the invention, there is provided a pharmaceutical formulation for administration by inhalation comprising a compound of formula (I), or a solvate thereof, together with a long−acting β2−adrenoreceptor agon...  
WO/2003/066659
The invention relates to an improved method for obtaining highly pure, crystalline betulinic acid from a methanolic extract of ground plane bark and/or plane rind. The invention also relates to a highly pure, crystalline betulinic acid, ...  
WO/2003/062260
The invention provides novel compounds that are quaternary amine derivatives of betulin and other triterpenes. The compounds have antibacterial, antifungal, and surfactant properties.  
WO/2003/053993
The invention makes steroids available having formula (I) wherein R1 is O, (H,H), (H, OH), NOH, wherein OH is optionally etherified or esterified; R2 is hydrogen, or (C1-15)acyl; and the dotted lines indicate one or two optional bonds, f...  
WO/2003/020214
Disclosed are compounds that exhibit high transport across the intestinal wall of an animal. The compounds may optionally be linked to drugs that are poorly absorbed or poorly transported across the intestinal wall after oral administrat...  
WO/2002/094849
Steroids containing a cyclohexene moiety are efficiently oxidized to the corresponding &agr , β−unsaturated ketone using copper iodide and t−butyl hydroperoxide. A steroid compound containing the &agr , β−unsaturated ketone struc...  
WO/2002/092618
Disclosed is 17$g(a)-hydroxy-4-androstenh-3-one and the novel derivatives thereof of general formula (I), in addition to a method for the production thereof and medicaments containing said compounds are used to regulate spermatogenesis a...  
WO/2002/049622
The invention relates to a matrix transdermal system containing (21S)-21-hydroxy-21-methyl-14,17-ethano-19-norpregna-4,9,15- triene-3,20-dione comprising a polyacrylate adhesive.  
WO/2002/048171
Disclosed are androgenic steroids of the (14$g(b), 17$g(a))-17-(hydroxymethyl) type. The invention relates to an improvement hereof, which is based on the presence of a $g(b)-oriented, annellated cyclopropyl group which includes carbon a...  
WO/2002/017895
Aldosterone receptor antagonists for the prevention and treatment of cognitive dysfunction are disclosed.  
WO/2002/015920
We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/...  
WO/2002/009719
Antitumor agents comprising as the active ingredient a compound selected from among maslinic acid, erythrodiol, uvaol, betulinic acid, betulin, physiologically acceptable salts thereof and derivatives thereof.  
WO/2002/000682
The invention discloses a steroid compound having the formula (1), wherein dotted bonds represent optional double bonds; R¿6? is H, =CH¿2?, or -CH¿3?, or -CH¿2?-CH¿3?; R¿7? is H, C¿1-4?-alkyl, C¿2-5? alkenyl or C¿2-5?-alkynyl, w...  
WO/2001/049293
The present invention relates to a pharmaceutical composition that is lower toxicity and antiphlogistic as well as anti-exudation. The composition contains escin of general formula (I) and escin of general formula (II) as active componen...  
WO/2001/047945
The present invention provides a process for preparing the antiprogestational agent, 17$g(a)-acetoxy-11$g(b)-[4-N,N-(dimethylamino)phenyl]-21-met hoxy-19-norpregna-4,9-diene-3,20-dione, intermediates useful in the process, and processes ...  
WO/2001/042274
The invention relates to novel 14,15-cyclopropanosteroids of the 19-norandrostane series having the general formula (I), preparation thereof and pharmaceutical compositions containing said compounds. Compounds of the formula (I) have an ...  
WO/2001/042275
The invention relates to novel unsaturated 14,15-cyclopropane-androstanes of the general formula (I), to their production and to pharmaceutical compositions containing these compounds. The compounds of formula (I) are progestational and/...  
WO/2001/040255
The disclosed invention relates to the unexpected finding of novel steroids which are characterized by a 14$g(b),15$g(b)-cyclopropane ring and a 17$g(a) hydroxymethyl group. These steroids according to the invention are found to have in ...  
WO/2001/015717
Medicinal compositions and preparations for administration comprising ginseng, which is useful as a cell protecting agent and a remedy for nerve trauma, its extract, ginseng components, metabolites thereof or salts thereof (for example, ...  
WO/2001/005805
The invention relates to novel C-19-halogen-substituted steroids of the androst-9(11)-ene series, i.e. 17$g(b)-hydroxy-19-halogen-androsta-4,9(11)-diene-3-one of general formula (I) and to methods for the production thereof. The inventio...  
WO/2000/068245
The present invention relates to pharmaceutically active 14$g(b)-H-sterols, to pharmaceutical compositions comprising them and to the use of these novel compounds for the preparation of medicaments. More particularly it has been found th...  
WO/2000/059922
The invention relates to novel equilenine derivatives of general formula (I) and methods for producing the same and medicaments containing said derivatives. The novel compounds are potent antioxidants and are used in the geriatric prophy...  
WO/2000/056757
The invention provides compositions comprising formula 1 steroids, e.g., 16alpha-bromo-3beta-hydroxy-5alpha-androstan-17-one hemihydrate and one or more excipients, typically wherein the composition comprises less than about 3% water. Th...  
WO/2000/053619
The disclosed invention relates to the unexpected finding of steroids for use as androgens which are characterized by a configuration opposite to that of natural steroids, viz. 14$g(a), 17$g(b). These steroids according to the invention ...  
WO/2000/047603
The invention relates to novel compounds as pharmaceutical agents which have in vitro a higher affinity to estrogen receptor preparations of the rat prostate than to estrogen receptor preparations of the rat uterus and which preferably h...  
WO/1999/067276
Disclosed are novel 14,15-cyclopropanosteroids of the 19-norandostane series, having general formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to a method for the production thereof and to pharmace...  
WO/1999/067275
Disclosed are novel unsaturated 14,15-cyclopropanoandrostanes of general formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to the production thereof and pharmaceutical preparations containing said ...  
WO/1999/058549
Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.  
WO/1999/051623
A medicine composition comprising, as an active component, an oleanane derivative represented by formula (1), wherein Me represents methyl, with respect to X, Y and Z; any of (1), (2), (3) and (4) is selected: (1) X and Z together repres...  
WO/1999/044616
A series of novel steroid derivatives are described. The steroid derivatives are antibacterial agents. The steroid derivatives also act to sensitize bacteria to other antibiotics including erythromicin and novobiocin.  

Matches 101 - 150 out of 375