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JP2998287B2 |
Presented are a glycyrrhetic acid derivative of the following formula [wherein R is a hydrogen atom or an unsubstituted or substituted alkyl group of 1 to 18 carbon atoms] or a pharmacologically acceptable salt thereof, which has antioxi...
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JPH11302181A |
To provide an antiobestic medicine as a natural medicine not having a side effect and habituation and having high activity and high biological safety. This antiobestic medicine contains as active ingredients (i) Momordin I and/or (ii) Mo...
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JPH11302180A |
To provide an antiulcer medicine as a natural medicine not having a side effect and habituation and having high activity and high biological safety. This antiulcer medicine contains as active ingredients (i) Momordin I and/or (ii) Momord...
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JP2959785B2 |
Disclosed are novel classes of anti-androgens including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.
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JP2950616B2 |
A triterpene derivative represented by general formula (I), which has an antiendotheline activity and is useful for preventing and treating the diseases of the cardiovascular system, and a pharmaceutical composition thereof. In formula (...
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JP2951657B1 |
[wrap up] [Task] Provided is a substance capable of promoting the absorption of iron citrate in the brain and improving the cure rate thereof, which is effective for the treatment of patients with Alzheimer's disease. General formula [Ch...
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JPH11246415A |
To obtain the subject composition having excellent steroid 5α- reductaseII-type-specific inhibitory effect, and useful in e.g. hair growth stimulants, anti-acnevulgaris bacteria skin drugs, by including a triterpene compound as active i...
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JPH11193242A |
To obtain the subject inexpensive medicine exhibiting an effect to widely inhibit the infections of serologically different influenza viruses or an effect to inhibit the proliferation of the viruses after the infections and highly safe f...
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JP2880434B2 |
The invention relates to a Gymnema inodorum roasted tea having glucose absorption inhibiting action. The Gymnema inodorum roasted tea is obtainable by roasting dried Gymnema inodorum leaves at 150-200 DEG C. The thus obtained Gymnema ino...
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JP2850051B2 |
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JP2841174B2 |
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JP2837271B2 |
PCT No. PCT/DE90/00688 Sec. 371 Date Jul. 15, 1991 Sec. 102(e) Date Jul. 15, 1991 PCT Filed Sep. 6, 1990 PCT Pub. No. WO91/04265 PCT Pub. Date Apr. 4, 1991.A process for the production of progresterone derivatives of general formula I (I...
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JPH10509959A |
The object of the present invention is to provide asiatic acid derivatives, its pharmaceutically acceptable salts or esters. Asiatic acid, its trisaccharide asiaticoside and mddecassic acid, extracted from Centella asiatica have been use...
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JPH10245395A |
To prepare antipruritic derived from Kochiae fructus (a dried fruit of Kochia scoparia (L.) Schrad) having excellent antihistaminic activities, and further antiallergic and antiinflammatory activities, hardly causing side effects by usin...
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JPH10508301A |
Saponin preparations based on defined compositions of purified saponin fractions derived from the bark of Quillaja saponaria Molina are disclosed. The saponin preparations are useful in immunostimulating complex (iscom) matrices. The sap...
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JP2746041B2 |
PURPOSE: To obtain the subject derivative for therapeutic agent, etc., for bone metabolic diseases such as osteoporosis, consisting of a steroid derivative containing a phosphoric acid group and capable of making a steroid compound to ac...
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JPH1072488A |
To obtain the subject agent useful as a preventing agent for gastric ulcer, duodenum ulcer, etc., a treating agent for these peptic ulcers or a preventing agent for their relapse by using a saponin having a specific structure as an activ...
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JP2727096B2 |
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JP2724114B2 |
PURPOSE: To obtain a new compound having endothelin receptor antagonistic action and accordingly useful for the prevention and treatment of circulatory diseases such as vasoplasm and hypertension and also useful for decreasing the nephro...
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JP2708157B2 |
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JPH1028548A |
To obtain a new glycyrrhetinic acid derivative, having a structure with a sweetness quality and a string sweetness similar to that of sugar and useful for a low-caloric sweetener substitutive for the sugar. This new glycyrrhetinic acid d...
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JPH1017431A |
To obtain a skin ununiformity improver that remedies darkened human skin, or prevents the human skin from darkening, by the use of a specific compound having improving effects on ununiformity of the skin, and/or its salt. This skin ununi...
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JPH1017591A |
To prepare an antiinflammatory agent, comprising aescin Ib having angeloyl group or aescin IIb having the angeloyl group which is a saponin ingredient of a conker of Aesculus Hippocastanum L. or a mixture thereof as an active ingredient,...
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JPH107696A |
To provide a pentacyclic ursen type triterpene originating from Japanese plum tree as a physiologically active substance and a process for easily and inexpensively extracting and producing the same. Water shoots of Japanese plum trees wh...
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JP2694048B2 |
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JP2660404B2 |
1. The products of formula I : see diagramm : EP0245170,P90,F1 in which R1 represents an alkynyl radical having from 2 to 8 carbon atoms optionally substituted by a radical selected from the radicals, hydroxyl, halogen, trialkylsilyl, al...
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JPH09241295A |
To obtain a skin preparation for external use, excellent in effects on protection of skin and retention of water, capable of activating metabolism of skin, increasing elasticity of skin, by blending a protein, a protein hydrolyzate, etc....
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JPH09241122A |
To obtain a new preparation for external use for the skin excellent in skin protection and moisturizing effect, containing a combination of a specific compound derived from escin in the extract of the seeds of Aesculus hippocastanum with...
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JPH09241121A |
To obtain a sebum secretion depressor capable of exhibiting a suppressing or preventing effect on local accumulation of fat and improving a beauty appearance of the skin by using a specific compound obtained from escin in the extract of ...
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JPH09241296A |
To obtain a skin preparation for external use, capable of raising affinity for skin of escinol for suppressing production of pigment cell activator and improving effectiveness of escinol, excellent in safety and feeling in use, by blendi...
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JPH09241123A |
To obtain a cosmetic suppressing drying of the skin without inducing glittering, sticking and crumbling of makeup by blending a specific compound obtained from the extract of the seeds of Aesculus hippocastanum in a cosmetic obtained by ...
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JPH09241120A |
To obtain a preparation for external use for skin good in usability and stability, and excellent in moisturizing effect, containing a water-soluble polymer and a specific compound derived from escin, an extract of the seeds of Aesculus h...
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JPH09241162A |
To obtain an antiinflammatory agent, comprising an escinol as an active ingredient, excellent in antiinflammatory effects and good in usability and safety. This antiinflammatory agent comprises an escinol of the formula (R1 is H or OH; R...
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JPH09241124A |
To obtain a preparation for external use for skin high in safety, further improved in skin whitening effect, and capable of further improving dull skin, containing a combination of at least one kind of substance selected from L-ascorbic ...
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JPH09208598A |
To obtain an antiulcer medicine containing friedelan-3-β-ol or a β- sitosterol compound as an active ingredient, exhibiting an antiulcer action, especially exhibiting an improving effect on a hydrochloric acid ethanol gastric mucosa le...
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JP2636914B2 |
Antigestagens are useful for softening the nonpregnant cervix.
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JPH09194498A |
To obtain a new saponin having suppressing actions on sugar absorption and alcohol absorption and useful for prevention of obesity and prevention and treatment, etc., of diabetes mellitus as a suppressor of absorption of carbohydrate, be...
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JPH09169648A |
To obtain the subject composition excellent in inhibitory action on proliferation of mesangium cell, effective for an animal nephritis model, low in toxicity, useful for treating nephritis, containing a specific compound as an active ing...
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JPH09151198A |
To obtain an analgesic antiinflammatory agent comprising an extracted component from a plant hardly having an adverse action as an active ingredient. This analgesic antiinflammatory agent comprises friedelin, friedelan-3-α-ol or friedel...
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JP2612770B2 |
The present invention provides quaternary ammonium-substituted saponin ethers having improved electrostatic and hydrophobic interactive activities, and therefore very useful in hair-care and skin-care products. The product of the inventi...
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JPH09504781A |
(57) [Summary] Immerse the saponoside mixture in an anhydrous ethanol bath at a temperature of 40-60 ° C; perform the first rapid high temperature filtration step in a 40-60 ° C bath to separate polar and non-polar impurities from the ...
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JPH09100294A |
To obtain an arterialization inhibitor useful for treatment, etc., of cancer, chronic articular rheumatism, arteriosclerosis, etc., by using demethylzeylasteral or its N-methyldiethanolamine salt as an active ingredient. This arterializa...
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JPH09100212A |
To obtain a solid aqueous cosmetic such as a foundation, readily removable with a sponge, etc., excellent in touch in use such as a refreshing feeling, an enriching feeling, fresh-looking, etc., and stability with time, comprising a spec...
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JPH09100295A |
To obtain the subject new compound, which is a physiologically active substance, comprising specific triterpenoid saponins, having axis-cylinder process elongating actions and useful as an active ingredient, etc., of a therapeutic agent ...
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JP2588267B2 |
New 19,11 beta -bridged steroids of the general formula I (I) where R1 stands for a methyl or ethyl radical, R2 for a hydrogen or chlorine atom or a C1-C4-alkyl radical, B and G, which are the same or different, respectively for a hydrog...
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JPH0952899A |
PURPOSE: To obtain the subject antagonist useful for the therapy, prophylaxis, etc., of allergosis, inflammatory affection, cardiovascular diseases, etc., by compounding a terpene derivative including new compounds isolated from an extra...
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JP2582088B2 |
Antigestagens are used to produce drugs for inhibiting terine prostaglandin synthesis.
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JPH09501433A |
The applications discloses the treatment of inflammatory disorders, in particular those associated with rheumatoid, arthritis, gout, gouty arthritis and Behcet's syndrome, with 2-methoxyestradiol.
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JPH08319295A |
PURPOSE: To obtain a nucleic acid compound having an orientation fixed by a cyclic skeleton, comprising a non-nucleic acid cyclic skeleton containing two functional groups in the same direction and two nucleic acid chains bonded to the s...
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JP2552507B2 |
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