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Matches 1 - 50 out of 1,135

Document Document Title
WO/2018/113285A1
Disclosed is a method for preparing sodium aescinate, relating to the technical field of plant extraction. The method comprises: semen aesculi is taken and subjected to alcohol extraction, the resulting extracting solution is subjected t...  
WO/2018/103766A1
Disclosed is a compound as shown in formula I. Also disclosed are a synthesis method for the compound, and uses of the compound in the preparation of anti-cancer and anti-inflammatory drugs and a drug which treats hepatitis C.  
WO/2018/088439A1
Provided are: a compound represented by formula (I); a retinoid metabolic pathway inhibitor comprising the same; an agent for increasing the ratio of memory T cells; a prophylactic and/or therapeutic agent for cancer or an infectious dis...  
WO/2018/073551A1
The present invention relates to a chemical composition characterized in that it comprises: - the molecule A or a physiologically acceptable salt thereof, and/or: - the molecule B or a physiologically acceptable salt thereof, said molecu...  
WO/2018/069086A1
Triterpenoid derivatives and compositions comprising said triterpenoids derivatives of Formula (I) are described, wherein R=-C(O)NHOH. Said triterpenoids and compositions show capacity to bind PHD2, stabilize HIF-1α and HIF-2α proteins...  
WO/2018/063010A9
The invention relates to a novel lupeol derivative, which is the ester of 4-picolinic acid (isonicotinic acid) and 20(29)-lupen-3.beta.-ol (lupeol), having structural Formula (1). The novel lupeol derivative is a result of modification o...  
WO/2018/063010A1
The invention relates to a novel lupeol derivative, which is the ester of 4-picolinic acid (isonicotinic acid) and 20(29)-lupen-3.beta.-ol (lupeol), having structural Formula (1). The novel lupeol derivative is a result of modification o...  
WO/2018/025462A1
Provided is a method for economically and easily producing soya saponins without crushing seeds or plant bodies or treating with an organic solvent. The method for producing soya saponins comprises: incubating or growing a legume plant b...  
WO/2018/006804A1
Provided are an application of a compound represented by formula I as a ligand of an orphan nuclear receptor Nur77, and an application for preventing or treating a disease related to the orphan nuclear receptor Nur77.  
WO/2018/006801A1
The present application relates to an orphan nuclear receptor Nur77 ligand and an application thereof. The application specifically relates to a compound represented by formula I and application of the compound as the orphan nuclear rece...  
WO/2018/002849A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoid compounds that possess unique antiviral activity are provided as HIV maturation inhibitor...  
WO/2017/220050A2
Disclosed are an azithromycin pharmaceutical composition and a medical use thereof for cough relief. The azithromycin pharmaceutical composition contains azithromycin and a natural product compound (I) separated from dried rhizoma arisae...  
WO/2017/220050A3
Disclosed are an azithromycin pharmaceutical composition and a medical use thereof for cough relief. The azithromycin pharmaceutical composition contains azithromycin and a natural product compound (I) separated from dried rhizoma arisae...  
WO/2017/215678A3
Provided is a cefaclor pharmaceutical composition. The cefaclor pharmaceutical composition comprises cefaclor and a naturally produced compound (I) having a new structure and isolated from dry roots and stems of Acorus tatarinowii. When ...  
WO/2017/215678A2
Disclosed are a cefaclor pharmaceutical composition and effects thereof for protecting acute lung injuries. The cefaclor pharmaceutical composition provided in the present invention comprises cefaclor and a naturally produced compound (I...  
WO/2017/210636A1
The disclosure relates to compositions, methods, and kits comprising glycyrrhetinic acid derivatives for selectively eradicating cancer cells (e.g., leukemic cells) in a population or subject, and related methods of treating cancer (e.g....  
WO/2017/185273A1
A method for preparing saikoside from bupleurum longiradiatum, comprising: washing bupleurum longiradiatum, picking out impurities from the bupleurum longiradiatum, air-curing the bupleurum longiradiatum, and grinding the bupleurum longi...  
WO/2017/177326A1
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...  
WO/2017/150723A1
Algae that generates a sterol and a sterol production method that uses the algae. According to the present invention, a sterol is produced by culturing algae, such as strain AJ7867 (FERM BP-22304) and strains derived therefrom, that has ...  
WO/2017/134596A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhib...  
WO/2017/128981A1
Provided are a compound (LQC-C) with a structure as shown by formula (I) and a preparation method thereof and a use thereof in preparing anti-tumour drugs. The compound has a significant activity in inhibiting the growth of tumour cell l...  
WO/2017/125870A1
The present invention relates to compounds characterized by having a structure according to the following Formula I: (I) or a pharmaceutically acceptable salt thereof. Compounds of the present invention are useful for the treatment or pr...  
WO/2017/088080A1
The present invention relates to a method for obtaining and purifying saponins from plant extracts, which comprises extracting saponins and subsequently removing impurities by adding a salt selected from the group of alkaline earth metal...  
WO/2017/083795A1
Disclosed are methods and compositions for treating alcohol dependence by administration to a patient of an inhibitor of 11β-hydroxysteroid dehydrogenases (11β-HSD) to modulate glucocorticoid effects. One such compound is the 11β-HSD ...  
WO/2017/076332A1
The present invention relates to a pentacyclic triterpenoid compound providing an acetyl-CoA carboxylase 1 (ACC1) protein regulating effect and uses of the compound. The compound of the present invention can be applied directly to ACC1 p...  
WO/2017/070615A1
Described herein, inter alia, are compositions and methods for treating or preventing obesity and using the same.  
WO/2017/064628A1
The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers...  
WO/2017/051355A1
The present invention relates to compounds characterized by having a structure according to the following Formula (I), or a pharmaceutically acceptable salt thereof. Compounds of the present invention are useful for the treatment or prev...  
WO/2017/053868A8
Disclosed herein are C4 modified oleanolic acid derivatives of the formula: Formula (X) or Formula (XII), as well as analogs thereof, wherein the variables are defined herein. In addition, disclosed herein are pharmaceutical compositions...  
WO/2017/053868A1
Disclosed herein are C4 modified oleanolic acid derivatives of the formula: Formula (X) or Formula (XII), as well as analogs thereof, wherein the variables are defined herein. In addition, disclosed herein are pharmaceutical compositions...  
WO/2017/025899A1
Formula (I) The present invention relates to novel C28-amides with C3-modifications of triterpene compounds of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates,...  
WO/2017/025901A1
The present invention relates to compounds of novel C28-analogues with C3- modifications of triterpene derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hy...  
WO/2017/021922A1
The present invention relates to compounds of novel substituted amides of triteripene derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers...  
WO/2017/017609A1
The present invention relates to compounds characterized by having a structure according to the following Formula I, or a pharmaceutically acceptable salt thereof. Compounds of the present invention are useful for the treatment or preven...  
WO/2017/017607A1
The present invention relates to compounds characterized by having a structure according to the following Formula (I), or a pharmaceutically acceptable salt thereof. Compounds of the present invention are useful for the treatment or prev...  
WO/2017/017630A1
The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. ...  
WO/2016/193309A1
The present invention relates to synthetic bis esters of hederagenin, and their use in ruminants to improve ruminant growth performance, reduce rumen methane emission, reduce urine ammonia excretion, and/or to reduce rumen acetate to pro...  
WO/2016/184400A1
The present invention relates to a novel 18α-glycyrrhetinic acid derivative and pharmaceutical use thereof. The compound has a weak inhibitory activity on 11β-hydroxyl steroid dehydrogenase, thus effectively alleviating an adrenocortic...  
WO/2016/178092A8
Formula (I) The invention relates to C-3 novel triterpenone with C-28 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated dise...  
WO/2016/178092A3
Formula (I) The invention relates to C-3 novel triterpenone with C-28 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated dise...  
WO/2016/135553A1
The present invention relates to a protoescigenin derivative of formula (I) having pharmacological properties, process of its preparation, use of such compound as medicament especially for treating vascular disorders, as well as to a pha...  
WO/2016/086453A1
Disclosed are a use of a pentacyclic triterpenoid compound in preparing a cholesterol ester transfer protein (CETP) inhibitor, and a pharmaceutical composition thereof.  
WO/2016/086496A1
The present invention relates to the technical field of biopharmaceutical. Provided is a pentacyclic triterpenoid compound and use thereof as human carboxylesterase inhibitor. The pentacyclic triterpenoid compound has a 11-deoxygenate-gl...  
WO/2016/077561A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhib...  
WO/2016/077569A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhib...  
WO/2016/077572A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhib...  
WO/2016/039359A1
The present invention relates to: a terpenoid derivative which is capable of activating a Keap1/Nrf2/ARE signaling pathway and has an excellent anti-inflammatory activity and an excellent cell-protecting activity; and a sustained-release...  
WO/2016/029888A1
The present invention provides amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use as medicaments for treating neuropsychiatric disorders associated with an ...  
WO/2016/001820A1
The present invention relates to novel betulinic proline imidazole derivatives and related compounds, compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.  
WO/2015/195776A1
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivaties that possess unique antiviral activity are provided as HIV maturation inhibi...  

Matches 1 - 50 out of 1,135