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Matches 1 - 50 out of 29,114

Document Document Title
WO/2019/054198A1
The present disclosure provides an antibody binding to an intranuclear protein of influenza virus and use of the same. The present disclosure provides an antibody which recognizes a peptide comprising the 205th-231st amino sequence in SE...  
WO/2019/049663A1
The present invention addresses the problem of providing a method for assessing whether or not an artificial protein having a specific introduced non-naturally-occurring amino acid can be synthesized by the synthesis system provided by r...  
WO/2019/050872A1
Provided herein are methods for the improved production of periplasmic- targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.  
WO/2019/050504A1
Embodiments in accordance with the present disclosure are directed to polymer beads and uses thereof, including forming libraries of compounds for screening and assay purposes. An example method includes using logic circuitry to: select ...  
WO/2019/048654A1
A process for splitting protein materials of animal or plant origin to peptides with molecular weights from below 10KDato 260 KDa, decontamination of bone meal and destroying allergenic proteins. For these purposes the protein materials ...  
WO/2019/050522A1
The present invention relates to xin yi extracts and a method for preparing the same. The treatment of periodontitis by using the xin yi extracts is also provided.  
WO/2019/043096A1
The present invention relates to a method for purifying anti-IL-6 receptor antibodies from a sample comprising said antibodies and impurities, through the use of a three-chromatographic columns procedure, including a chromatography on Fl...  
WO/2019/043067A1
The present invention relates to a method for purifying proteins, such as Fc fusion proteins or antibodies, from a sample comprising said proteins and impurities, through the use of a three- chromatographic columns procedure, including a...  
WO/2019/045149A1
The present invention provides a method for purification of a sulfatase using metal chelating chromatography without use of tags (such as His-tag, etc.). An embodiment provides a method for purifying a sulfatase comprising the steps of: ...  
WO/2019/043604A1
The invention relates to peptide conjugates, methods for making peptide conjugates, conjugates produced by the methods, and pharmaceutical compositions comprising the conjugates. Methods of eliciting immune responses in a subject and met...  
WO/2019/046634A1
Disclosed herein is a method of designing small peptides for interacting with, binding to, or modulating the activity of, known protein or peptides. Further disclosed herein are methods for selecting sequences likely to have high binding...  
WO/2019/040973A1
A method for the synthesis of a cyclic ornithine-proline-D-cyclohexylalanine-tryptophan- arginine pentapeptide of Formula A; wherein R1 and R2 are, independently, -H, or -C(O)R3 where R3 is -Ch2Ph, - CH2CH2Ph, -CH=CHPh, -C(NHAC)CH2Ph; th...  
WO/2019/040920A1
The present invention relates to methods of preparing a therapeutic exosome using a protein newly-identified to be enriched on the surface of exosomes. Specifically, the present invention provides methods of using the proteins for affini...  
WO/2019/040411A1
Embodiments disclosed herein provide compositions, methods, and uses for solubility-enhancing protein (SEP) tags. Certain embodiments provide expression vectors for the production of a soluble protein or polypeptide of interest (i.e., a ...  
WO/2019/037393A1
The present invention provides a polypeptide compound having high affinity for GLP-1 receptors, the molecular structure thereof being as shown in the following formula (I), wherein R represents Evans blue or a derivative group thereof. T...  
WO/2019/040671A1
Provided herein, in some embodiments, are methods and compositions for purifying antibodies from cellular cultures using one or more thiol containing additives during a purification process, for example in a chromatographic purification ...  
WO/2019/039968A1
The invention relates to the field of bioengineering. Proposed are peptides having a specific sequence that are capable of binding imiglucerase with a high degree of effectiveness. Antibodies or fragments thereof that include given seque...  
WO/2019/039545A1
The present invention provides a chromatography carrier that has excellent antifouling properties and exhibits excellent pressure-resistant and fracture-resistant performance. This chromatography carrier comprises a polymer having a part...  
WO/2019/039602A1
Provided is a carrier for affinity chromatography having high immunoglobulin purification efficiency. This protein contains two or more domains linked together by a linker. The domains have affinity to immunoglobulins. The linker is a pe...  
WO/2019/040498A1
Provided is a non-natural macromolecular assembly that includes at least two peptide bundles and at least one linker moiety covalently linking the peptide bundles. The assembly may be used, for example, in liquid crystal materials and fi...  
WO/2019/034955A1
A method for purifying phycocyanin from a phycocyanin-containing solution is provided. The method comprises a first step of partially purifying the solution by aqueous two-phase separation (ATPS) and a second step of purifying the phycoc...  
WO/2019/035935A1
Compositions and methods for the preparation of high purity arginase and high efficiency preparation of monosubstituted polyethylene glycol conjugation of arginase are provided, as are methods for using arginase in combination with aspar...  
WO/2019/033869A1
Disclosed is an Andrias davidianus cartilage preparation. The Andrias davidianus cartilage enzymatic extract of the present invention is obtained by the following method, comprising obtaining cartilage from Andrias davidianus, proteolyzi...  
WO/2019/035478A1
The purpose of the present invention is to provide a method for producing a peptide-bond-containing polymer in high yield and in a short time. The method for producing a peptide-bond-containing polymer provided by the present invention c...  
WO/2019/036631A1
The present invention provide novel immunofiber compositions for protein or peptide purification and simple and cost-efficient methods and systems using these compositions. In some embodiments, the immunofibers comprise a customized Z-33...  
WO/2019/036626A1
A method for purifying a glycosylated recombinant protein of interest from a contaminant is disclosed that is suitable for industrial production purposes to remove gelactins and other host cell contaminants, such as metallic cations, fro...  
WO/2019/030171A1
The invention relates to novel methods for synthesizing amanitin derivatives having an amino group attached to position 6' of the central tryptophan moiety. The invention furthermore relates to a novel amanitin derivative having an amino...  
WO/2019/028980A1
Provided in the present invention are an anti-human papilloma virus and anti-CD humanised dual targeting antibody, and a composition, a preparation method, and an application thereof, the antibody comprising a murine-human chimeric antib...  
WO/2019/030173A1
The invention relates to novel methods for synthesizing amanitin derivatives having a hydroxy group attached to the central tryptophan moiety. The invention furthermore relates to novel amanitin derivatives having a hydroxy group attache...  
WO/2019/025388A1
The present invention relates to a purified veterinary allergen extract enriched. In particular, the invention relates to a purified veterinary allergen extract enriched with Der f 15 and Der f 18. The invention further relates to use of...  
WO/2019/028168A1
Materials and methods for generating protein-polymer conjugates on solid supports are provided herein. The methods can include, for example, reversibly immobilizing a protein on a solid support, modifying the protein by adding polymer su...  
WO/2019/027368A1
Described herein is an operationally simple, one-pot solid-supported preparation of saturated stapled peptides. Following completion of ruthenium-catalysed metathesis, solid-phase transfer hydrogenation was achieved using triethylhydrosi...  
WO/2019/027168A2
The present invention relates to a method for obtaining a Bordetella pertussis-derived PRN protein, the method comprising a freezing and thawing process capable of effectively increasing an extracted level of PRN protein. In the present ...  
WO/2019/024150A1
Provided in the present invention are a transcription factor composition comprising transcription factors ELL, AFF and CRTC. A mammalian protein expression system may be obtained by co-transfecting an expression vector comprising a gene ...  
WO/2019/028172A1
Provided herein are methods of capturing and purifying recombinant proteins from a liquid cell culture including a dual-use filtration and chromatography pod, filtration and chromatography pods, and the use of these pods.  
WO/2019/024311A1
Provided are a solution and method for preserving a fluorescent antibody, a kit including the solution, use of the solution and the kit in an immunoassay. The solution includes gelatin, cysteine, gentamicin and sodium citrate.  
WO/2019/019492A1
The present invention provides a method of synthesizing PT141. The method of the present invention comprises synthesizing PT141 linear peptide in a solid phase; and adding the linear peptide into a buffer solution and performing cyclizat...  
WO/2019/021049A1
The present invention relates to a stationary phase for the purification of polyclonal anti-Giardia IgG and IgY antibodies, as well as a method for purifying polyclonal anti-Giardia IgG and IgY antibodies by affinity chromatography. The ...  
WO/2019/023634A1
The present disclosure provides efficient and reliable methods for preparing cyclized peptidic compounds. Advantageously, the currently described methods allow for on-resin cyclization using a limited number of processing steps, while in...  
WO/2019/018403A1
Methods for making hemoglobin based blood substitute preparations and hemoglobin based blood substitute preparations. The methods involve preparing a low purity erythrocyte protein fraction comprising hemoglobin protein and endogenous no...  
WO/2019/018836A1
Infusion therapy for primary or metastatic tumors includes infusion of fluids that are into supplying blood vessels at concentration and flow rates that kill tumor cells or but don't kill normal cells. The infused fluids can be known tox...  
WO/2019/016154A1
The present invention is in the field of purification and protein purification in particular. The invention provides improved techniques for the industrial-scale purification of proteins and other biomolecules. More specifically, it rela...  
WO/2019/018572A1
Disclosed herein are peptide-polymer conjugates for the delivery of peptide epitopes sublingually to elicit an immune response.  
WO/2019/011900A1
The present invention relates a method for incubating liquids, to a method for preparing a biopharmaceutical drug, and to a device for the preparation of a biopharmaceutical drug.  
WO/2019/011922A1
The invention relates to a method for producing block polymers (1), comprising a first (5, 60A, 50) and a second block (20, 60B, 50), comprising the method steps: A) providing a first block (5, 60A, 50) having a nucleophilic peptide sequ...  
WO/2019/014595A1
The current disclosure provides compositions and methods for wound closure. The disclosure provides an device comprising: a) a material with a surface comprising a modified fibrinogen or a modified fibrin, wherein the modified fibrinogen...  
WO/2019/009317A1
Provided are: a novel compound usable as an organic tag which has a high stability under acidic conditions in peptide synthesis, etc.; and a method for highly efficiently producing a peptide wherein the compound is used as an organic tag.  
WO/2019/009388A1
The purpose of the present invention is to provide: an anti-human CEACAM5 antibody Fab fragment which is expected as useful in diagnosing cancer, in particular, colon cancer, breast cancer, lung cancer, thyroid cancer or cancer metastasi...  
WO/2019/003180A1
Disclosed herein are underlying aspects, including optimized media and growth conditions, for the enhanced secretion of a self-assembling extracellular self assembling native protein from a Yarrowia lipolytica strain through liquid cultu...  
WO/2019/001778A1
A method of continuous separation of a plasmid from a process feed in an apparatus with at least three chromatography columns packed with separation matrix particles, wherein while one chromatography column is loaded with the process fee...  

Matches 1 - 50 out of 29,114