Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 451 - 500 out of 1,628

Document Document Title
WO2005037859A9
The present invention provides a sensor and methods for determining kinase activity.  
WO2005018575A3
The present disclosure relates to the field of cellular tumorigenesis and cancer biology. More specifically, the present disclosure relates to tumorigenesis and cancer in estrogen-responsive cell types, including cell types such as testi...  
WO2004112572A3
This invention relates to the diagnosis and/or monitoring of patients with inflammatory diseases or conditions, e.g., immunologic, hematologic, vascular, or infectious diseases or conditions, by determining levels of complement pathway c...  
WO2004071414A3
The present invention provides synthetic HCV epitopes, antibodies that recognize and bind to the synthetic HCV epitopes, polynucleotides that encode the synthetic HCV epitopes, and immune effector cells raised in response to the presenta...  
WO2004065547A3
The present invention is directed to an antigen found on the surface of rat and human pancreatic cancer cells and provides antibodies of high specificity and selectivity to this antigen as well as hybridomas secreting the subject antibod...  
WO2005009363A3
The present invention relates to methods and compositions designed for the treatment or management of pre-cancerous conditions, especially in order to prevent, delay, or decrease the likelihood that the pre-cancerous condition will progr...  
WO2004080412A3
Methods and compositions for treating cancer patients that include administering at least one or more hybrid derivatives of paclitaxel that simultaneously display improved aqueous solubility, chemical stability under physiological condit...  
WO2005009217A3
The present invention relates to methods and compositions designed for the treatment or management of pre-cancerous conditions, especially in order to prevent, delay, or decrease the likelihood that the pre-cancerous condition will progr...  
WO2004110367A3
An isolated and/or purified Sdr surface protein from S. capitis and nucleic acids encoding them are provided which includes the SdrX protein which possesses collagen binding activites and the SdrZL protein which possesses SdrZ-like prope...  
WO/2004/103270A3
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structure...  
WO2003022126A3
Compositions and methods for the therapy and diagnosis of cancer, particularly colon cancer, are disclosed. Illustrative compositions comprise one or more colon tumor polypeptides, immunogenic portions thereof, polynucleotides that encod...  
WO2004094644A3
Disclosed are compositions comprising in vivo expressed polynucleotides of V. cholerae. Also disclosed are methods of using such polynucleotides and the corresponding expression products to treat V. cholerae infection.  
WO2004110390A3
Disclosed are compositions that include anti-CD74 immunoconjugates and a therapeutic and/or diagnostic agent. Also disclosed are methods for preparing the immunoconjugates and using the immunoconjugates in diagnostic and therapeutic proc...  
WO/2005/037859A2
The present invention provides a sensor and methods for determining kinase activity.  
WO2004072105A3
The present invention features peptides, peptidomimetics and methods of their use for binding to Inhibitor of Apoptosis Proteins (IAPs) in cells and prevents the IAP's from exerting their apoptosis-suppressing function with caspases in t...  
WO/2005/032461A2
The present invention provides a composition including an isolated or recombinant peptide component that has osteogenic cell proliferative activity. The peptide, which promotes proliferation of osteoblasts, is useful for treatment of fra...  
WO/2005/032491A2
The present invention provides a Mycoplasma pneumoniae community acquired respiratory distress syndrome (CARDS) toxin, biologically active fragments/domains of the CARDS toxin, antibodies to the CARDS toxin and nucleic acids encoding the...  
WO2004094600A3
The Efb protein from Staphylococcus aureus has now been shown to have the ability to bind to the C3 protein which is a crucial component in the activation of complement, and a specific C3 binding region has been located at the C-terminal...  
WO2004103266A3
A composition for use in managing withdrawal from an addictive substance is described. The composition includes one or more peptides having specific activity for the ∈ and/or gamma isozyme of protein kinase C (PKC). The peptide(s) can ...  
WO2004108747A3
The invention relates to a conjugate comprising at least one target-seeking unit, which bonds specifically to receptors on the surface of endothelial cells, and at least one effector unit coupled to said unit by means of a linker. The ef...  
WO2004065409A3
The present invention relates to peptide mimotopes of lipooligosaccharide from nontypeable Haemophilus influenzae as vaccines.  
WO/2005/018575A2
The present disclosure relates to the field of cellular tumorigenesis and cancer biology. More specifically, the present disclosure relates to tumorigenesis and cancer in estrogen-responsive cell types, including cell types such as testi...  
WO/2005/016244A2
Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastr...  
WO/2005/011607A2
The truncated ErbB2 receptor (p95ErbB2) is shown to differ from the full-length ErbB2 receptor in its association with other ErbB receptors. The truncated receptor preferentially associated with ErbB3, whereas full length ErbB2 heterodim...  
WO/2005/009363A2
The present invention relates to methods and compositions designed for the treatment or management of pre-cancerous conditions, especially in order to prevent, delay, or decrease the likelihood that the pre-cancerous condition will progr...  
WO/2005/009222A2
This invention describes unique patterns of distribution of ganglioside GM1, in non-capacitated sperm and demonstrates that the pattern of distribution of GM1 undergoes changes that can be correlated with the process of capacitation and/...  
WO/2005/009378A2
The present invention features hybrid polypeptides providing ORF0657n and ORFO190 epitopes, nucleic acid encoding for the different polypeptides, and a method for evaluating the ability of an immunogen to produce a protective immune resp...  
WO/2005/009396A2
The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria, including in particular bacteria in which a RAP-type and/or TRAP-type molecule...  
WO/2005/009217A2
The present invention relates to methods and compositions designed for the treatment or management of pre-cancerous conditions, especially in order to prevent, delay, or decrease the likelihood that the pre-cancerous condition will progr...  
WO/2005/007680A1
Described is a method for the preparation of a mixture of peptides, having an arginine and lysine content of at least 20 w/w%, based on the protein content, from at least one protein source, to a preparation comprising a mixture of argin...  
WO/2004/112572A2
This invention relates to the diagnosis and/or monitoring of patients with inflammatory diseases or conditions, e.g., immunologic, hematologic, vascular, or infectious diseases or conditions, by determining levels of complement pathway c...  
WO/2004/110367A2
An isolated and/or purified Sdr surface protein from S. capitis and nucleic acids encoding them are provided which includes the SdrX protein which possesses collagen binding activites and the SdrZL protein which possesses SdrZ-like prope...  
WO/2004/110390A2
Disclosed are compositions that include anti-CD74 immunoconjugates and a therapeutic and/or diagnostic agent. Also disclosed are methods for preparing the immunoconjugates and using the immunoconjugates in diagnostic and therapeutic proc...  
WO/2004/108751A1
The present invention relates to a cardio myopeptidin which is isolated from the hearts of non-human healthy mammals. The molecular weight of the cardio myopeptidin is less than 10000 Dalton, the peptide content thereof being 75%∼90%, ...  
WO/2004/108747A2
The invention relates to a conjugate comprising at least one target-seeking unit, which bonds specifically to receptors on the surface of endothelial cells, and at least one effector unit coupled to said unit by means of a linker. The ef...  
WO/2004/103270A2
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structure...  
WO/2004/103266A2
A composition for use in managing withdrawal from an addictive substance is described. The composition includes one or more peptides having specific activity for the ∈ and/or &gammad isozyme of protein kinase C (PKC). The peptide(s) ca...  
WO/2004/101504A1
The invention relates to a stereoselective method of preparing $g(g)-amino vinyl sulphones. The inventive method comprises: the reaction of the corresponding N-protected (1-aminoalkyl) epoxide with a thiol, or an alkaline metal salt ther...  
WO2004093662A3
It is to provide a method and a kit for detecting the prognosis of cancer at high accuracy in a simple and rapid manner at low cost. The method is specifically a method for detecting the prognosis of cancer, at least including a step of ...  
WO2004048591A3
This application includes methods and compositions for evaluating a genetic locus associated with longevity and methods for evaluating information from groups of individuals. A longevity-associated locus was identified in gene that encod...  
WO/2004/093662A2
It is to provide a method and a kit for detecting the prognosis of cancer at high accuracy in a simple and rapid manner at low cost. The method is specifically a method for detecting the prognosis of cancer, at least including a step of ...  
WO/2004/093807A2
The invention features targeted cytotoxic compounds and methods relating to their therapeutic use for the treatment of neoplasia and other conditions.  
WO/2004/094600A2
The Efb protein from Staphylococcus aureus has now been shown to have the ability to bind to the C3 protein which is a crucial component in the activation of complement, and a specific C3 binding region has been located at the C-terminal...  
WO/2004/094644A2
Disclosed are compositions comprising in vivo expressed polynucleotides of V. cholerae. Also disclosed are methods of using such polynucleotides and the corresponding expression products to treat V. cholerae infection.  
WO/2004/091490A2
The invention features somatostatin-dopamine chimeric analogs and methods relating to their therapeutic use for the treatment of neoplasia, acromegaly, and other conditions.  
WO/2004/090548A1
The invention relates to an active nanostructured carrier with high sensitivity for separation and/or analysis, its preparation method, and a nano-label and its labeling method. The invention also relates to a biochip and a polypeptide d...  
WO/2004/089297A2
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structure...  
WO/2004/083154A1
A process for isolating low molecular weight (“LMW”) peptides from tissue in situ comprising the steps: a) homogenizing the tissue; b) mixing the homogenized tissue with an organic solvent to form a fully-wetted slurry; c) standing o...  
WO2004037164A3
Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds or (2) by the reaction between at least ...  
WO/2004/080412A2
Methods and compositions for treating cancer patients that include administering at least one or more hybrid derivatives of paclitaxel that simultaneously display improved aqueous solubility, chemical stability under physiological condit...  

Matches 451 - 500 out of 1,628