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Patent Searching and Data


Matches 601 - 650 out of 17,226

Document Document Title
WO/2014/175445A1
Provided are a peptide that enables surface treatment of a scaffold for tissue repair that makes it possible to accelerate the repair of living tissue without using a material that negatively affects the repair of living tissue, a comple...  
WO/2014/173980A2
The stabilization of subtilisins by peptide aldehydes, hydrosulfite adducts thereof or peptide methyl ketones, is particularly effective in liquid ADW detergents which contain a strong sequestering builder.  
WO/2014/134203A9
Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically modified by oxidation and alkylation of ...  
WO/2014/170347A1
Compounds of general formula (I): their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in the ...  
WO/2014/060942A3
The disclosures herein provide aminoacid derivatives containing therapeutic copolymer of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These salts may...  
WO/2014/170295A1
Compounds of general formula (I) wherein R1, R2, R3, R4, R5 and A take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly as agents able to potentiate the effect of antifungal drugs.  
WO/2014/169153A1
Compositions comprising peptides with a chemical tag are disclosed. Such compositions can be used to modulate formulation properties of a biomolecule. The peptides are useful as cancer therapeutics and for modulating the physiochemical p...  
WO/2014/076422A9
The invention relates to substituted anionic compounds consisting of a backbone consisting of a discrete number u between 1 and 8 (1 < u < 8) of identical or different saccharide units, bonded by identical or different glycosidic bonds, ...  
WO/2014/161072A1
This application pertains to α-boryl isocyanates, wherein the boronate moiety is in the form of an N-methyliminodiacetic acid (MIDA) boronate of the Formula (2) and the utility of said compounds in the synthesis of the borylamide motif ...  
WO/2014/161863A1
The present invention refers to peptides of general formula (I) and their salts for dermatological and cosmetic use, in particular for preventing or reducing the signs of cutaneous aging and for the treatment of wounds (i.e. burns, lacer...  
WO/2014/153666A1
Indoline Granzyme B inhibitor compounds, compositions that include the compounds, and methods for inhibiting Granzyme B in a subject or for treating a disease, disorder or condition treatable by inhibiting Granzyme B using said compounds...  
WO/2014/157485A1
The present invention addresses the problem of discovering a short chain peptide with an anti-aging effect and providing a novel anti-aging agent containing said peptide as an active ingredient. It was found that peptides, which have at ...  
WO/2014/152674A1
The invention relates to enzyme and protease inhibitor containing water-soluble films, and their use in detergents.  
WO/2014/147124A1
The present invention relates to a method of synthesizing a peptide product comprising at least one hydantoin group. The peptide product may be used as a reference material for the quality control of pharmaceutical peptides, particularly...  
WO/2014/149440A1
An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substitute...  
WO/2014/144004A1
Compositions with antifungal activity and methods of using such compositions are provided herein. In particular the compositions are peptides of SEQ ID NO; I and variations thereof. The peptides may contain L or D amino acids and may be ...  
WO/2014/145507A1
The invention provides a process of preparing 4-amino-4-oxobutanoyl peptides and cyclic analogues thereof of Compound (I) and pharmaceutically acceptable salts thereof.  
WO/2014/139008A1
A compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or racemic mixture or stereoisomer thereof, and methods for preventing or treating an LDL-cholesterol-related disease or disorder using such compound(s),...  
WO/2014/144087A1
The disclosure provides crystalline Sovaprevir forms. The crystalline forms of Sovaprevir comprise a Form A polymorph, a Form B polymorph, a Form C polymorph, a Form D polymorph, and a Form E polymorph. The Form A, B, C, D, and E polymor...  
WO/2014/137869A1
Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.  
WO/2014/136780A1
[Problem] To provide a novel fluorescent probe for detecting the activity of calpain. [Solution] A compound represented by general formula (I) or a salt thereof.  
WO/2014/134203A1
Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically modified by oxidation and alkylation of ...  
WO/2014/134543A1
The invention described herein pertains to processes for preparing tubulysins and derivatives thereof. The invention described herein also pertains to processes for preparing tubulysin conjugates. The invention described herein also pert...  
WO/2014/132262A1
Compositions comprising self-assembled hydrogel particles formed of short peptides which comprise one or more aromatic amino acid residue(s) in an inverted emulsion are disclosed. Such hydrogel particles which encapsulate an active agent...  
WO/2014/134562A1
The disclosure provides methods of preventing, ameliorating or treating disruption of mitochondrial function and symptoms thereof. The methods provide administering aromatic-cationic peptides in effective amounts to prevent, treat or ame...  
WO/2014/133129A1
A method for manufacturing reduced glutathione using electrolytic reduction of oxidized glutathione involving the use of a cathode tank and an anode tank separated by a separating membrane, wherein the reduced glutathione is manufactured...  
WO/2014/129969A1
This disclosure relates to therapeutic agents comprising polypeptides and peptides that include the amino acid sequence motif arginine-lysine-aspartic acid [RKD] and their use in the treatment of conditions associated with abnormal angio...  
WO/2014/126836A1
Tubulysin compounds of the formula (I) where R1, R2 R3a, R3b, R4, R5, W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.  
WO/2014/121590A1
Flavonoids compounds of formula (I) or isoflavonoids compounds of formula (II), useful for treatment of HCV diseases, are disclosed. In the compounds, R1 is selected from formula(III), formula(IV) or formula(V); R2, R3, R4, R5 are select...  
WO/2014/121725A1
Provided is a polypeptide, the amino acid sequence of which is SLPQ. The polypeptide is prepared by fermented skimmed milk by Lactobacillus helveticus. The polypeptide can enhance immunity of a body, so also provided are food, health pro...  
WO/2013/049697A9
The present disclosure provides methods of preventing or treating renal ischemia-reperfusion injury in a mammalian subject and methods for chronic treatment of ARVD, including administering an effective amount of an aromatic-cationic pep...  
WO/2014/118779A1
The invention provided herein presents a novel family of antifouling agents based on hydroxylated and fluorinated compounds.  
WO/2014/116187A1
The present invention relates to hydrogels comprising a plurality of amphiphilic peptides and/or peptoids capable of self-assembling into three-dimensional macromolecular nanofibrous networks, which entrap water and form said hydrogels, ...  
WO/2014/066936A9
The present invention relates to a supramolecular structure comprising a plurality of peptide foldamer units, where each foldamer unit: (i) independently comprises at least three sequential ß-amino acid residues, one of which is N-acyla...  
WO/2014/102571A1
Novel peptidomimetics exhibiting affinity for opioid receptors, possessing general formula show on Figure 1, for gastrointestinal or peripheral administration in the form of a pill, infusion, injection or implant in the treatment of peri...  
WO/2014/104352A1
Provided is a means for diminishing the reaction interference which antithrombin III causes when used in a limulus test and for thereby enabling the limulus test with the antithrombin III to be carried out with high accuracy. Antithrombi...  
WO/2014/104981A1
The present invention provides an amphiphilic linear peptide and/or peptoid as well as a hydrogel that includes the amphiphilic linear peptide/peptoid. The amphiphilic linear peptide/peptoid is capable of self-assembling into three-dimen...  
WO/2014/101828A1
Disclosed is a method for preparing Romidepsin. The present invention relates to the pharmaceutical synthesis. The present invention is based on a method of solid phase synthesis. First, coupling is performed between resin and carboxyl g...  
WO/2014/095657A1
Synthesis of an intermediate useful in the synthesis of a viral protease inhibitor, and its use in the preparation of said inhibitor.  
WO/2014/096343A1
The invention relates to an amorphous form of telaprevir, its preparation via novel crystalline Form C of telaprevir (also referred to as "crystalline Form C" or "Form C"), and telaprevir compositions comprising said amorphous form and F...  
WO/2014/094353A1
Disclosed herein are maytansinoid drug linker derivatives which can be linked to a antigen binding unit (Abu), and maytansinoid drugs linked with an antigen binding unit (Drug- Linker-Antigen binding Unit: D-L-Abu), for targeted delivery...  
WO/2014/096090A1
The invention relates to a novel thyrotropin releasing hormone (TRH) receptor subtype in human central nervous system (CNS) that is pharmacologically distinct from the TRH receptor subtype in human pituitary. The invention provides a mea...  
WO/2014/096551A1
The invention relates to novel linker-payload molecule conjugates. The invention also relates to novel cell binder-linker-payload molecule conjugates, in particular antibdy conjugates of dolastatin or auristatin derivatives.  
WO/2014/090172A1
Provided is a milk-derived biologically active polypeptide having an amino acid sequence of DELQ, which has in-vitro antioxidation activity and promotes immune activity of human body. In-vitro antioxidation and in-vitro immunity promotio...  
WO/2014/052451A3
Disclosed herein are insulin analog dimers having unique insulin receptor agonist activity based on insulin polypeptide sequences, the site of dimerization and the length of the dimerization linker that connects the two insulin polypepti...  
WO/2014/090180A1
Provided is a milk-derived biologically active polypeptide having an amino acid sequence of QEPV, which has in-vitro antioxidation activity and enhances immunity of human body. The polypeptide has good biological antioxidation activity, ...  
WO/2014/090183A1
Provided is a milk-derived biologically active polypeptide having an amino acid sequence of LPLP, which has in-vitro antioxidation activity and enhances immunity of human body. The polypeptide has good biological antioxidation activity, ...  
WO/2014/089189A2
A system, method, and apparatus for Internet Protocol television streaming are disclosed. An example method includes receiving a request in a content delivery network from a client device to receive television programming from a particul...  
WO/2014/083578A1
The invention disclosed herein relates to novel solomonamide analogues of formula I having anti-inflammatory activity and viable synthetic route for the preparation thereof.  
WO/2014/085637A1
The present invention concerns novel antibiotic compounds, which are lantibiotics, the processes for their preparation, their pharmaceutically acceptable salts, pharmaceutical compositions containing the lantibiotics, and their use as an...  

Matches 601 - 650 out of 17,226