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Matches 551 - 600 out of 102,766

Document Document Title
WO/2018/080072A2
The present invention relates to a novel macrolide-based compound, a method for producing the same, and a pharmaceutical composition, which is for preventing or treating malaria and contains the novel macrolide-based compound as an activ...  
WO/2018/079714A1
Provided is a method for reprograming in vitro human mature hepatocytes into hepatocyte precursor cells having the ability to self-renew. A method for preparing human hepatocyte progenitor cells, said method comprising culturing human ma...  
WO/2018/075197A1
The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodimen...  
WO/2018/073342A1
The present invention provides a method of recovering viable microbial cells from a complex sample, said method comprising: a) providing a sample having a volume of at least 1 ml; b) contacting said sample with a buffer solution and one ...  
WO/2018/075502A1
Methods and compositions for detecting the presence of a pathogen are described. In particular, this document provides a method of detecting a pathogen-associated nucleic acid in a biological sample of a subject, where the method compris...  
WO/2018/076008A1
Provided are compositions and methods for used in solubilizing, stabilizing and expressing proteins. The proteins are fusion proteins that contain a protein of interest. The fusion proteins contain segments of Ribose Binding Protein (RBP...  
WO/2018/074514A1
Provided is an agent acting on a transcellular ion transporter in the intestinal tract, said agent comprising a bacterium belonging to the genus Bifidobacterium or the genus Lactobacillus or a processed product thereof [except the follow...  
WO/2018/073143A1
The present invention concerns a method, a test kit and a culture medium for testing for Gram negative bacteria exhibiting multiple resistance to aminoglycoside antibiotics, wherein the method, test kit and culture medium detect resistan...  
WO/2018/073409A1
The present invention relates to a polypeptide capable of specifically inhibiting human adenylyl cyclase (5) wherein said polypeptide does essentially not inhibit human adenylyl cyclase (6). The present invention also relates to the poly...  
WO/2018/074578A1
The purpose of the present invention is to develop a new technique for improving secretory production of a heterologous protein using a coryneform bacterium and to provide a secretory production method for a heterologous protein. In the ...  
WO/2018/074760A1
The present invention relates to a novel Metschnikowia persimmonesis KIOM_G15050 strain (KCTC 12991BP) isolated from an old calyx of a persimmon and a use thereof. Specifically, the novel Metschnikowia persimmonesis KIOM_G15050 strain (K...  
WO/2018/072031A1
There is provided a fusion construct of formula (I): X-A-linker-B-Z (I) wherein : (1) A and B are identical or different and are independently: (a) a polypeptide comprising a SACOL0029 polypeptide as set forth in any one of the sequences...  
WO/2018/071744A1
The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.  
WO/2018/070521A1
In one embodiment, the present invention addresses the problem of: providing an agent for inhibiting a lectin pathway and an alternative pathway; and others. In one embodiment, the present invention relates to: a fusion polypeptide conta...  
WO/2018/069499A1
The invention discloses novel methods for the synthesis of ethanol. In particular the invention provides methods for producing a biomass characterised by a reduced content in acetyl groups. The invention also discloses materials for use ...  
WO/2018/071564A1
Disclosed herein are methods and compositions for the production of L-3,4- dihydroxyphenylalanine from a bacteria.  
WO/2018/069881A1
Exemplary embodiments of the present disclosure are directed towards biofertilizer compositions comprising Chryseomicrobium palamuruense PU1T and methods thereof. The biofertilizer compositions in some embodiments further comprises of ag...  
WO/2018/070141A1
Provided is a modified obligately anaerobic acetic acid-producing microorganism in which the activity of at least one enzyme selected from the group consisting of a restriction enzyme, modification enzyme, and recognition enzyme which co...  
WO/2018/068347A1
Provided are recombinant plasmids containing the heterodimeric snake venom protein Agkisacutacin A chain gene and Agkisacutacin B chain gene, respectively, cell strains containing the recombinant plasmids, and a method for expressing the...  
WO/2018/069886A1
A therapeutic agent comprising a bacteria which expresses an inhibitor of MYC activity or a extract or product obtainable therefrom, for use in for use in the prevention or treatment o disease wherein MYC levels are elevated, such as can...  
WO/2018/066688A1
The present invention addresses the problem of providing a culturing method whereby it becomes possible to produce spores of a bacterium belonging to the genus Bacillus with high efficiency. Provided is a method for producing spores of a...  
WO/2018/065324A1
The present invention relates to lactic acid bacteria strains with the ability to tolerate antiseptics. The lactic acid bacteria strains have further the capacity to antagonize the growth of oral pathogens. Particularly, the lactic acid ...  
WO/2018/067599A1
Certain embodiments of the disclosure are directed to variant filamentous fungal cells, compositions thereof and methods thereof for increased production of one or more proteins of interest. More particularly, in certain embodiments, the...  
WO/2018/067825A1
Disclosed are compositions and methods relating to the treatment of a cancer via the induction of PDL1 and use of anti-PDL1 antibodies.  
WO/2018/067815A1
Compositions are provided that include a new Bacillus thuringiensis strain designated RTI545 for use in benefiting plant growth and controlling plant pests. In particular, the RTI545 strain is useful for controlling plant nematode, insec...  
WO/2018/067068A8
The present invention relates to methods of metabolic engineering to increase the levels of short branched-chain fatty acids (SBCFAs) produced by microorganisms such as yeast. More particularly, the invention provides methods to engineer...  
WO/2018/067887A1
Disclosed herein are compositions and methods for diagnosing fungal dysbiosis in the gut of a subject with cirrhosis that involves assaying a sample from the subject for bacterial taxa. These compositions and methods are based on the dis...  
WO/2018/067647A1
An improved stabilization buffer for use in the lyophilization of Neospora and other protozoans is disclosed. Also disclosed is an improved lyophilization method, which includes controlling ice nucleation during the freezing step.  
WO/2018/064758A1
The present invention relates to recombinant protein production in algal cells. In particular, the present invention provides methods for making recombinant polypeptides in association with accumulated lipid particles or chloroplasts. Th...  
WO/2018/067915A1
The present invention encompasses a micro-fluidic system having a closed-loop configuration in which inertial micro-fluidic separation of particles and/or cells is continuously repeated by feeding part of the output back to the input so ...  
WO/2018/066916A1
The present invention provides a novel Scenedesmus sp. algae, and an extract thereof. This extract of Scenedesmus sp. JD-052, which is a novel Scenedesmus sp. algae, shows a UV protection effect, and thus can be usefully used in the fiel...  
WO/2018/067068A1
The present invention relates to methods of metabolic engineering to increase the levels of short branched-chain fatty acids (SBCFAs) produced by microorganisms such as yeast. More particularly, the invention provides methods to engineer...  
WO/2018/066686A1
The purpose of the present invention is to provide a novel culturing method capable of efficiently producing spores. This culturing method is a method for culturing spore-forming bacteria by adding a spore inhibitor into a medium, the me...  
WO/2018/067846A1
Methods and compositions are provided for modulating expression of a target nucleic acid sequence within a non-E. coli cell. The method includes providing the cell with a guide RNA comprising a portion that is complementary to all or a p...  
WO/2018/062075A1
The present invention addresses the problem of providing a means for aseptically separating a suspending medium from a suspension. Provided is a tool equipped with at least: a hollow fiber-type separator for separating a liquid A from a ...  
WO/2018/062103A1
The present invention addresses the problem of providing novel FAD-GDH having high practicality. Provided is glucose dehydrogenase having the amino acid sequence of (a) or (b) as follows. (a) The amino acid sequence of SEQ ID NO. 1 in wh...  
WO/2018/059465A1
An anti-CD27 antibody, an antigen-binding fragment thereof, and a medical use of the same. Further, provided are a chimeric antibody comprising a CDR of the anti-CD27 antibody, a humanized antibody, a pharmaceutical composition comprisin...  
WO/2018/062573A1
The purpose of the present invention is to provide an efficient method for recovering cells such as microorganisms or animal cells; specifically, the present invention pertains to a method for recovering cells, said method including a st...  
WO/2018/060567A1
Process with the aim of preventing or slowing the appearance of unattractive signs, generated by the pollutants present in the atmosphere, on the skin, the scalp, the hair or the mucous membranes, or indeed of eliminating them, comprisin...  
WO/2018/058865A1
Provided is a dynamic fluid shear technology-based cell-wall breaking method for spirulina, comprising the following steps: (1) sucking spirulina in the surface layer of a water body by means of a plurality of fixed vortex well spirulina...  
WO/2018/064037A1
Methods of culturing microalgae in acetate toxicity conditions to induce the uptake of acetate, control contamination, increase the metabolic rate, increase the respiration rate, increase the accumulation of lipids, and decreasing the ac...  
WO/2018/062178A1
In the present invention, mutations involving amino acid substitution were introduced into various locations of diphosphomevalonate decarboxylase (MVD), and many variants of MVD were prepared. Then, regarding the variants, an enzymatic a...  
WO/2018/062203A1
The present invention provides an insect odorant receptor co-receptor that exhibits excellent detection sensitivity of odorants when bound with an odorant receptor to form an odorant receptor complex. This odorant receptor co-receptor is...  
WO/2018/058249A1
The present disclosure provides a system and method for identifying and targeting individual cells within a cell population for selective extraction of cellular content and a digital microfluidic device having at least one hydrophilic si...  
WO/2018/064338A1
Methods and compositions for the selection of nucleic acid processing and other enzymes, and more specifically for the selection of DNA polymerases and other enzymes with desired properties employing the directed evolution of enzymes by ...  
WO/2018/062914A1
The present application relates to novel lactobacillus sakei and a composition comprising the same.  
WO/2018/061719A1
The invention provides a method of measuring simply and accurately a microbial count in a sample. Namely, a method of measuring a microbial count including a step of blending a composition for preparing a culture medium for a microbial c...  
WO/2018/062201A1
The present invention provides an odorant receptor complex formed from an insect odorant receptor and an insect odorant receptor co-receptor, and which exhibits excellent detection sensitivity to odorous substances. This odorant receptor...  
WO/2018/062015A1
Provided is a lipid manufacturing method in which transformants into which are introduced genes coding for at least one protein selected from a group formed of proteins (A)-(C), described below, are cultured and in which fatty acids or l...  
WO/2018/062175A1
The purpose of the present invention is to provide molecularly altered adiponectin that can be produced as a uniform product, and has the same or greater activity compared to natural adiponectin. This molecularly altered adiponectin is p...  

Matches 551 - 600 out of 102,766