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WO/2018/064463A1 |
Described herein are systems and methods of flow-through electroporation can comprise a chamber with a first and a second portion, wherein the first portion is configured to receive cells and the second portion is in fluid communication ...
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WO/2018/053485A1 |
The disclosure provides methods and apparatus for high speed and sterile sorting of heterogeneous populations of cells to isolate homogenous populations. In embodiments, the disclosure provides a micropore array and collection tray situa...
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WO/2018/045373A1 |
Provided are systems for analyzing cellular distribution in an engineered tissue sample, which optionally is a bioprinted organ or tissue sample. In some embodiments, the systems include an ultrasound imaging system and a processing unit...
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WO/2018/016217A1 |
It was found that a substance can be easily and highly efficiently introduced into a plant cell without causing any damage and regardless of the kind of plant and tissue from which the cell is derived, by treating the plant cell with pla...
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WO/2018/008779A1 |
The present invention provides a method for controlling the growth direction of neuron dendrites, and a neuron culture controlled by the method. According to the present invention, the growth direction of neuron dendrites can be controll...
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WO/2018/009836A1 |
Methods of acquiring cellular and tissue vibrational patterning to identify signatures capable to induce pluripotency and commitment towards defined lineages, as well as survival under hostile conditions (i.e. oxidative stress) in both h...
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WO/2017/210664A1 |
The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to target opsins to the soma of cells in which they are expressed. Compositions of the invention may be ...
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WO/2017/210334A8 |
Methods and apparatuses for cell electroporation are provided. An apparatus includes a fluid transport structure, such as a pipette, that includes an electroporation structure defining a flow path having a constriction. The fluid transpo...
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WO/2017/208589A1 |
A cell treatment system is constructed, which is equipped with: an imaging device for imaging a cell culture vessel for the purpose of killing undesired cells among cells cultured on the cell culture vessel to obtain cell aggregates each...
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WO/2017/210334A1 |
Methods and apparatuses for cell electroporation are provided. An apparatus includes a fluid transport structure, such as a pipette, that includes an electroporation structure defining a flow path having a constriction. The fluid transpo...
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WO/2017/197531A1 |
Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensi...
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WO/2017/192760A1 |
Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems include multipl...
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WO/2017/188516A1 |
The present invention relates to a method for preventing cancerization of normal cells due to low-dose irradiation. The method enables effective prevention of cancerization of normal cells by means of low-dose radiation which is innocuou...
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WO/2017/188517A1 |
The present invention relates to an apparatus, for inhibiting oncogene-induced malignant cancerization, comprising an irradiation unit which is for irradiating low-dose radiation on a subject and a method, for inhibiting oncogene-induced...
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WO/2017/176764A1 |
A system, device and method for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where living cells and biologically active molecules flow through a channel that exposes ...
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WO/2017/170771A1 |
The present application provides a method for introducing the Cas9 protein into the fertilized egg of a mammal, and involves stages for (a) placing a mixture comprising a fertilized egg and a solution containing the Cas9 protein between ...
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WO/2017/157874A1 |
Device (1) for stimulation of at least one cell (2), and/or for stimulation of at least one electrochemical reaction, comprising at least one semiconductor (3) that is configured to convert electromagnetic radiation (4) into a charge sep...
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WO/2017/155166A1 |
The present invention relates to a cell reprogramming method using imposition of a physical stimulation-mediated environmental transition. More specifically, by subjecting differentiated or non-differentiated cells to physical stimulatio...
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WO/2017/155167A1 |
The present invention relates to a cell reprogramming apparatus using energy which can promote an environmental transition, more specifically to a cell reprogramming apparatus applying energy, such as ultrasonic waves, laser or heat trea...
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WO/2017/151950A1 |
The present disclosure provides compositions with enhanced bioactivity and methods of use in the treatment of disease or tissue injury and pain associated with disease conditions.
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WO/2017/146009A1 |
The present invention addresses the problem of providing a new method for controlling the enzyme productivity of microorganisms. The enzyme productivity of microorganisms is controlled by applying a pulsed electric field to the microorga...
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WO/2017/143162A8 |
Compositions and methods for cryoprotecting a biological tissue can involve a cryoprotective agent and a metal component that includes a metal foam, a metal foil, or a metal seed. The method allows the biological tissue to be rewarmed at...
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WO/2017/141685A1 |
This separation device separates dielectric particles. The separation device is provided with: a flow path (20); a plurality of electrodes (31, 32); a power source unit (40); and a control unit. The flow path (20) delivers a suspension c...
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WO/2017/143162A1 |
Compositions and methods for cryoprotecting a biological tissue can involve a cryoprotective agent and a metal component that includes a metal foam, a metal foil, or a metal seed. The method allows the biological tissue to be rewarmed at...
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WO/2017/129914A1 |
The invention relates to a method for producing pigments by cells capable of photosynthesis, according to which said cells are cultivated in conditions suitable for the development thereof, in order to obtain a biomass, the method compri...
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WO/2017/127686A1 |
Methods and devices for manipulating one or more particles (e.g., cells) in three dimensions using surface acoustic waves is described. Methods and devices for printing or more biological cells onto a substrate using surface acoustic wav...
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WO/2017/118390A1 |
Provided is a method for selectively manipulating a molecule. In the method, a distribution of or change in an external electric field, magnetic field or electromagnetic field is used to give a molecule a force moment or force, or to int...
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WO/2017/115220A1 |
Method for the optoinjection of exogenous material in a recipient biological cell enclosed by a membrane, which comprises: placing a biological cell on a planar surface of a substrate, transmitting a sub-ns pulsed laser beam through a va...
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WO/2017/117251A1 |
A handset for an electroporation device having an improved signal generator. The signal generator includes a primary winding and a plurality of secondary windings where the plurality of secondary windings are coupled together in a series...
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WO/2017/112898A1 |
An electroporation device having a battery pack including a plurality of battery cells and at least one lead in electrical communication with a circuit board. The battery pack including a safety switch and a controller for selectively pl...
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WO/2017/108957A1 |
The present invention relates to a hydrogen generating electrolytic cell (10) in a medium of alcoholic fermentation (100) comprising at least a first electrode (20) provided with a first charge and at least a second electrode (30) provid...
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WO/2017/097165A1 |
Exogenous molecule-loaded cells and a preparation method for exogenous molecule-loaded cells. The preparation method adopts a photoinduced perforating way for preparing, and comprises the following steps: (1) adopting a gold nano-structu...
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WO/2017/090808A1 |
The present invention relates to: a method for increasing a collagen yield, and collagen prepared using the same. To this end, the present invention comprises, in order to sterilize animal-derived tissue through irradiation without denat...
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WO/2017/087945A1 |
Methods of assessing cytolysis of cancer cells, including providing a cell-substrate impedance monitoring device operably connected to an impedance analyzer, wherein the device comprises a well for receiving cells and an electrode array ...
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WO/2017/073910A1 |
The present invention relates to a method for direct transdifferentiation into neurons using metal nanoparticles magnetized from an electromagnetic field, and to a cell therapeutic agent for the treatment of cerebral nerve diseases, comp...
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WO/2017/062838A1 |
Systems and methods of inducing large-scale optical transfection and generation of an immune response in target cells are presented. In preferred aspects large-scale optofection uses nanoparticles with target specific affinity moieties t...
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WO/2017/062901A3 |
EVs are connected to onset and progression of numerous diseases and can be used for their diagnosis. Methods and platform technology to isolate EVs and detect intravesicle phosphoproteins from biofluids are discussed. Secreted extracellu...
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WO/2017/057932A1 |
Disclosed in the present specification are: a method for preparing senescent melanocytes; senescent cells prepared by the preparation method; and a method for screening for a senescence-alleviating or skin whitening material by using the...
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WO/2017/059281A1 |
The present invention discloses adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF), their compositions and kits containing the ADSC's and their enriched fractions, and enzyme blends useful for thei...
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WO/2017/053136A1 |
A cleaning or grooming system that uses acoustic pressure shock waves can remove barnacles, algae, biofilms and other undesired materials from the hulls of ships, propellers, rudders, inlet ports for cooling of nuclear submarines, outlet...
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WO/2017/048146A1 |
The object of the invention is the method of detection and selection of hybridoma cells capable to produce desired antibodies, comprising seeding the hybridoma cells in a culture vessel with biofunctionalized surface, containing culture ...
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WO/2017/040995A1 |
Systems and methods for cell electroporation and molecular delivery using an intelligent, feedback controlled, microscale electroporation system for transfecting single cells.
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WO/2017/035253A1 |
There are provided, inter alia, methods for reacting an enzyme and its substrate, methods for purifying a protein and an enzyme reactor and its use thereof.
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WO/2017/029568A1 |
The invention relates to an apparatus and a method for the microbiological control of fluids in tubing that is electroconductive or not, by means of the application of electric and magnetic fields, from low-voltage and low-frequency alte...
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WO2017009431A1 |
The present disclosure relates to alight-driven system which is able to chemically modify an organic substrate with high efficiency and in a cost-effective manner. Also provided are methods for chemically modifying an organic substrate u...
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WO/2017/004709A8 |
A method for biosynthesis of polymer precursors, including, adipic acid, 1,6-hexanediol, 6-hydroxyhexanoic and 6-aminocaproic acids from carboxylic acids is provided. A method for biosynthesis of adipic acid from six-carbon dicarboxylic ...
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WO/2017/004709A1 |
A method for biosynthesis of polymer precursors, including, adipic acid, 1,6-hexanediol, 6-hydroxyhexanoic and 6-aminocaproic acids from carboxylic acids is provided. A method for biosynthesis of adipic acid from six-carbon dicarboxylic ...
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WO/2016/210348A3 |
Devices, methods, and systems are provided for extracting particles from a ferrofluid. Such methods may comprise receiving a flow of ferrofluid comprising target particles and background particles and generating a first, focusing magneti...
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WO/2016/194782A1 |
The present invention addresses the problem of preparing intracellular enzymes of yeast by a simple method. A pulsed electrical field is applied to yeast, and the enzymes extracted into the extracellular fluid are recovered.
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WO/2016/173548A1 |
A broken ganoderma lucidum spore product and a preparation method therefor, and food or a drink containing same. The preparation method for the broken ganoderma lucidum spore product comprises: putting 5-10 parts by weight of ganoderma l...
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