| Document |
Document Title |
|
WO/2021/007170A1 |
Provided herein are improvements in cell culture methods and compositions related thereto. In partial particular, provided herein are compositions and methods, and kits increasing the cellular division times and viability. Also provided ...
|
|
WO/2021/003451A1 |
Devices, systems, and kits for cell transfection are provided. A device includes a first electrode, a second electrode, and an electroporation zone therebetween where an electrical potential difference applied to the first and second ele...
|
|
WO/2020/257866A1 |
A method for transforming a cell with a nucleic acid molecule, comprising applying a voltage to a solution comprising (i) the cell; (ii) the nucleic acid molecule; (iii) a leading electrolyte; and (iv) a terminating electrolyte; wherein ...
|
|
WO/2020/263533A1 |
A method of identifying a lead or candidate compound that modulates the activity of GTPase-Activating Protein SH3 Domain-Binding Proteins (G3BP) is provided, which includes determining whether a compound modulates the interaction between...
|
|
WO/2020/256520A1 |
The present invention relates to a method for producing exosomes by electrical stimulation and, more specifically, to a method for producing exosomes, comprising the steps of: (a) applying radio wave electrical stimulation to cells and c...
|
|
WO/2020/249616A1 |
A method of upregulating the synthesis of pyruvate and/or a metabolite of pyruvate in a photosynthetic microorganism, a method for the photosynthetic production of a one, two, three or four carbon compounds, and a method for the producti...
|
|
WO/2020/232437A1 |
Disclosed are a system, device, and method for the electroporation of cells. Systems, devices and methods for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where livin...
|
|
WO/2020/146702A3 |
The present disclosure relates to methods of stimulating cell proliferation, promoting differentiation of cells, regenerating cells, promoting nodule formation, and promoting myotube formation. The methods include applying one or more pu...
|
|
WO/2020/210023A1 |
CAR T cell therapies have shown promise in treating human blood cell cancer. The preparation of CAR T cells involves many complex, time consuming steps prior to infusion of the CAR T cells into a cancer patient. One step in the process t...
|
|
WO/2020/210458A1 |
Methods of using pulsed focused ultrasound (pFUS) therapy to treat pancreatic disorders such as type 1 diabetes, pancreatitis, and pancreatic cancer are provided. The methods utilize pulsed focused ultrasound (pFUS) therapy either by its...
|
|
WO/2020/205862A1 |
An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multipl...
|
|
WO/2020/185622A1 |
Described is a low voltage, pulsed electrical stimulation device for upregulating expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.
|
|
WO/2020/183984A1 |
The present invention addresses the problem of providing a method for introducing a substance into a protoplast or an alga by electroporation under novel voltage applying conditions.　The problem can be solved by a method for introducin...
|
|
WO/2020/177456A1 |
Mutagenesis is carried out on hyaluronidase-producing Lactobacillus plantarum to obtain a high hyaluronidase-producing mutant strain of Lactobacillus plantarum CnT012-56, the accession number being: CGMCC NO.16836. Lactobacillus plantaru...
|
|
WO/2019/140019A8 |
A closed and modular fluidic system composed of one or more acoustic elements and cell processing reagents. The system employs a cellular manufacturing process for producing cell and gene therapy therapeutics.
|
|
WO/2020/171783A1 |
The present invention proposes a system (100) for subjecting a group of cells placed onto a surface (s1) of a vessel (4) when such vessel (4) is introduced into the system (100) and then the system (100) is run, to magnetofection using a...
|
|
WO/2020/161942A1 |
This growth promotion method promotes the growth of an organism. An organism disposed in a growth environment has imparted thereto a 0.5-1000MHz high frequency AC electrical field having a frequency band such that water dielectric loss b...
|
|
WO/2020/160501A1 |
Systems and methods described herein employ focused acoustic energy applied to a reservoir containing a fluid to eject a fluid sample from the fluid sample reservoir, e.g. to an inlet of an analytical device. In many embodiments, the eje...
|
|
WO/2020/145426A1 |
The present invention relates to a method for preparing a live attenuated vaccine by radiation and a live attenuated vaccine composition prepared thereby. More specifically, the present invention relates to: a method for preparing a live...
|
|
WO/2020/146702A2 |
The present disclosure relates to methods of stimulating cell proliferation, promoting differentiation of cells, regenerating cells, promoting nodule formation, and promoting myotube formation. The methods include applying one or more pu...
|
|
WO/2020/130106A1 |
Provided are: an electroporation device which, compared to devices in which electroporation is performed by reciprocating a solution (liquid droplets) containing a foreign substance and cells in an oil, facilitates an operation for colle...
|
|
WO/2020/125447A1 |
Provided is a preparation method for an exosome. A cell is stimulated by means of non-invasive ultrasound to regulate the microRNA expression abundance in the cell exosome. The method has good universality, is simple in operation, and ha...
|
|
WO/2020/128908A2 |
The disclosure provides methods for the selection and isolation of T cells expressing programmed cell death 1 (PD-1) and for selecting a PD-1 expression level of the isolated PD-1 expressing T cells. The disclosure also provides methods ...
|
|
WO/2020/123688A1 |
The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to direct and localize sensor molecules in the soma of cells in which they are expressed. Compositions o...
|
|
WO/2020/122702A1 |
The invention relates to a method for increasing the production of biomass and fatty acids in the alga Chlorella vulgaris Beyerinck and obtaining a biomass rich in lipids of type C:16 (palmitic acid), C18:1n-9 (oleic acid), C18:2n-6t (li...
|
|
WO/2020/080920A3 |
The present invention pertains to a method for overexpressing target genes and/or reprogramming cells, the method comprising: (a) obtaining transformed cells by introducing a vector into which a promoter and target genes have been insert...
|
|
WO/2020/071665A3 |
The present invention relates to an exosome for extending telomeres of cells, a composition comprising same, and a preparation method therefor and, more particularly, to an exosome for extending telomeres of cells, the exosome comprising...
|
|
WO/2020/086701A1 |
Compositions and methods for reducing nucleotide oxidation during electroporation, specifically the use of free radical scavengers to reduce electroporation-induced oxidation, are described. Compositions and methods for enhancing transfe...
|
|
WO/2020/080920A2 |
The present invention pertains to a method for overexpressing target genes and/or reprogramming cells, the method comprising: (a) obtaining transformed cells by introducing a vector into which a promoter and target genes have been insert...
|
|
WO/2012/145019A8 |
Provided are methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
|
|
WO/2020/071663A1 |
Disclosed is a method for producing exosomes having effects of skin regeneration and wound healing, comprising the steps of: providing ultrasonic stimulation directly or indirectly to cells; culturing a mixture of the cells and a medium ...
|
|
WO/2020/071652A1 |
Disclosed are a method for extending the telomeres of cells and cells having telomeres extended by physical stimuli, the method comprising the steps of: providing direct or indirect physical stimuli for cells; and incubating a mixture of...
|
|
WO/2020/071665A2 |
The present invention relates to an exosome for extending telomeres of cells, a composition comprising same, and a preparation method therefor and, more particularly, to an exosome for extending telomeres of cells, the exosome comprising...
|
|
WO/2020/071662A1 |
Disclosed is a method for preparation of exosomes having a hair regeneration effect, the method comprising the steps of: providing direct or indirect ultrasonic stimuli for cells; incubating a mixture of the cells and a medium for a pred...
|
|
WO/2020/070288A1 |
The inventors has developed a recombinant molecular system, named OptoFab, allowing the accurate control of the agonistic properties of an antibody-derived Fab fragment in time and in space using specific wavelengths of light. It consist...
|
|
WO/2020/030037A1 |
Provided is the use of a nanosecond pulsed electric field in improving cell stemness. Specifically, applying a nanosecond pulsed electric field to cells, especially stem cells, can effectively increase the expression level of stemness ge...
|
|
WO/2020/022382A1 |
A cell stimulation method that controls cell proliferation by stimulating cells without damaging the cells, by applying an AC electric field to the cells placed in an environment in which proliferation is possible.
|
|
WO/2020/010394A1 |
The present disclosure provides a method of dispersing agglomerated material in a preparation comprising influenza proteins. The method comprises subjecting the preparation to sonication.
|
|
WO/2020/008606A1 |
An ultrasonic vibrator (10) radiates ultrasonic waves toward a culture solution (3) retained together with cells (2) in a culture container (1). An acquisition unit acquires information indicating the state of sedimentation of cells (2) ...
|
|
WO/2020/000525A1 |
Disclosed is a cell sorting device, comprising a fluid pipe (1), a cell sorting unit (2), a cell delivery unit (3) and a magnetic field assembly (4). The cell sorting unit (2) comprises at least one cell sorting chamber (21), the fluid p...
|
|
WO/2019/232416A1 |
The present disclosure describes both compositions and methods that provide an agent encapsulated within a biopolymer. The methods as provided herein produce a spray-dried composition that exhibit enhanced yield and survivability of the ...
|
|
WO/2019/229722A1 |
The current subject matter provides a cell engineering platform of a diagnostic and clinical use scale for vector -free and/or viral delivery of payload/cargo compounds and compositions into non-adherent cells, lire platform achieves del...
|
|
WO/2019/231243A1 |
The present invention relates to a feeder cell expressing OX40L and a method for culturing natural killer cells using same. When the feeder cell expressing OX40L according to the present invention is co-cultured together with peripheral ...
|
|
WO/2019/227060A1 |
The disclosure provides compositions and methods for infecting a legume plant and/or increasing the yield of a legume plant by providing a population of light-activated, nitrogen-fixing bacteria by illuminating a population of nitrogen-f...
|
|
WO/2019/226926A1 |
Some embodiments herein include methods of ameliorating, inhibiting, reducing, treating, slowing the progression of, or preventing a decline in respiratory function associated with a neurological disease of a patient, for example amyotro...
|
|
WO/2019/222333A1 |
Disclosed herein are devices, apparatuses and methods for generating self-sustaining gaseous and non-gaseous gradients across a cell support structure and for culturing one or more cells or tissues under hypoxic conditions. Methods of ge...
|
|
WO/2019/220025A1 |
The present invention relates to the field of converting algal biomass. The present invention relates to a method for obtaining fat-soluble and water-soluble compounds from a biomass of eukaryotic or prokaryotic microalgae (cyanobacteria...
|
|
WO/2019/203894A1 |
Articles, systems, and methods in which electromagnetic energy is converted to heat (e.g., for the purpose of inducing or inhibiting phase change of a material disposed over a surface) are generally described.
|
|
WO/2019/173800A1 |
A closed and modular fluidic system composed of one or more acoustic elements and cell processing reagents. The system employs a cellular manufacturing process for producing cell and gene therapy therapeutics.
|
|
WO/2019/164928A1 |
Disclosed herein are multi-cuvette cartridges (130, 222), flow cells (245, 342), and electrical pulse systems (100) for treatment of large volumes of biological samples with pulsed electric fields. The multi-cuvette cartridges systems ma...
|
