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WO/2020/064776A1 |
The invention relates to the use of a composition comprising a rod-shaped, aerobic, Gram-positive microorganism for the degradation of liquid polyether-based polyurethane, and to the composition derived from the degradation of said polye...
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WO/2020/067487A1 |
The present invention provides a method for producing L-methionine by fermentation using a bacterium which has been modified to overexpress a 1st gene and a 2nd gene, such as genes having the nucleotide sequences shown in SEQ ID NOs: 1 a...
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WO/2020/057476A1 |
Provided is an application of trehalase in fermentative production. The trehalase has amino acid sequences shown in SEQ ID NO.6, SEQ ID NO.7, and SEQ ID NO.8. Provided are methods for producing and applying trehalase, particularly being ...
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WO/2020/060970A1 |
The present disclosure generally relates to methods for the recovery of amines from aqueous mixtures. In particular, the disclosure relates to methods for separating amines from amine-containing aqueous mixtures by adjusting the pH of th...
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WO/2020/059480A1 |
Provided are: a method for producing immobilized microorganisms having excellent filtration properties; and a production method for an amino acid using the immobilized microorganisms. This production method for immobilized microorganisms...
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WO/2020/057308A1 |
Disclosed is an NADH-dependent amino acid dehydrogenase and an application thereof in increasing lysine yield. The amino acid dehydrogenases are aspartate dehydrogenase derived from Pseudomonas aeruginos, aspartate semialdehyde dehydroge...
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WO/2020/054598A1 |
Provided is a method for producing a 3-hydroxy-4-aminobenzoic acid compound using a microorganism. A method for producing a 3-hydroxy-4-aminobenzoic acid compound, comprising the step of bringing a 4-aminobenzoic acid compound into conta...
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WO/2020/056410A1 |
Methods for modulating immunosuppression are disclosed. This invention relates the fields of T cell regulation and therapeutic immunosuppression. More specifically, the invention provides compositions and methods for selective immunosupp...
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WO/2020/054934A1 |
The present invention relates to a novel yeast mutant strain for producing a ceramide precursor and a generation method therefor and, more specifically, to a yeast mutant strain for high production of sphingosine or dihydrosphingosine-ce...
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WO/2020/051188A1 |
Compositions and methods for the production of L-glufosinate are provided. The method involves converting racemic glufosinate to the L-glufosinate enantiomer or converting PRO to L-glufosinate in an efficient manner. In particular, the m...
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WO/2020/051420A1 |
This disclosure provides engineered strains of Corynebacteria for the cost-effective production of lysine, tools and methods used to produce the engineered strains, and methods of using the engineered strains to produce lysine.
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WO/2020/043077A1 |
Provided is an enzymatic method for preparing L-threo/erythro-p-methylsulfonylphenyl serine, in particular, a method for preparing L-threo/erythro-p-methylsulfonylphenyl serine by catalyzing glycine and p-methylsulfonylphenyl serine usin...
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WO/2020/036963A1 |
The present invention relates to amorphous and crystalline forms of valbenazine salt and the methods for their preparation.
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WO/2020/034209A1 |
Provided is an amino acid dehydrogenase mutant. The amino acid sequence of the mutant is obtained by mutating the amino acid sequence shown in SEQ ID NO: 1. The mutation comprises at least one of the following mutation sites: 64th, 94th,...
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WO/2020/037338A1 |
A strain of Rhodococcus rhodochrous in which a gene coding at least part of a nitrile hydratase enzyme or any gene coding a protein involved in the transcription, translation or formation of at least part of the nitrile hydratase enzyme ...
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WO/2020/031201A1 |
The present invention relates to highly pure 6-aminohexanoic acid of formula-1 which is free of organic volatile impurities, caprolactam impurity and improved process for its preparation thereof. The present invention also relates to an ...
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WO/2020/025656A1 |
The invention relates to anutritional supplement comprising a combination of one or more β-aspartyl-containing dipeptides,oroligomers thereof, or salts thereof, wherein each of the β-dipeptides comprises β-L-aspartyl as a first amino ...
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WO/2020/025646A1 |
An isolated w-transaminase enzyme comprising an amino acid sequence of SEQUENCE ID NO: 1, or encoded by a nucleic acid sequence of SEQUENCE ID NO: 2, is provided which is derived from marine sponge Pseudovibrio sp.. Also provided are fun...
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WO/2020/027251A1 |
A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective ...
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WO/2020/020844A1 |
The invention pertains to a process for manufacturing aromatic nitriles, wherein a starting material selected from the group of aromatic primary alcohols and aromatic aldehydes is contacted under reaction conditions in a reaction vessel ...
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WO/2020/013346A1 |
A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3'-phosphoadenosine-5'-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobacteri...
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WO/2020/011725A1 |
A method for purifying ethanolamine from a fermentation composition and products thereof.
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WO/2020/009168A1 |
The activity of the wild-type hydroxynitrile lyase (HNL) obtained to date is insufficient for industrial use, and HNL having better activity has been demanded. The present inventors introduced various amino acid mutations predicted on th...
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WO/2020/005834A1 |
Methods and materials related to producing aspartic acid, β-alanine and salts of each thereof are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, methods and materials for producing aspartic acid by direct fer...
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WO/2020/006058A2 |
Described herein are engineered cells including ones having synthetic methylotrophy which include an NADH-dependent enzyme capable of converting G3P to 3PG (e.g., B. methanolicus gapN) and/or fructose-1,6-bisphosphatase, along with hexul...
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WO/2019/243293A1 |
The present invention relates to novel urethanases for the enzymatic degradation of polyurethanes and to an enzymatic process for the complete degradation of polyurethanes in defined monomers.
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WO/2019/243087A1 |
The present invention relates to a process for the preparation of Droxidopa by means of an improved enzymatic reduction of a compound of formula (II): (II), wherein R1, R2 is independent hydrogen, acetyl, R3 is hydrogen, a C1-C4 linear o...
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WO/2019/240579A1 |
The invention provides a production process for the production of an aromatic epoxide derived compound, the production process comprising: (i) an epoxidation stage comprising: reacting an aromatic compound and a peroxide in the presence ...
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WO/2019/238725A1 |
The present invention relates to a method for preparing a methionine analogue, comprising contacting a host cell with L-homoserine and one or more nucleophiles and cultivating said host cell and said one or more nucleophiles of (a) in a ...
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WO/2019/240243A1 |
The purpose of the present invention is to provide a selenoneine production method with which selenoneine can be produced at high yields even if an inorganic selenium compound is used as the selenium compound. This purpose is achieved by...
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WO/2019/241132A1 |
The present invention provides engineered tyrosine ammonia-lyase (TAL) polypeptides and compositions thereof. In some embodiments, the engineered TAL polypeptides have been optimized to provide enhanced catalytic activity and enhanced ac...
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WO/2019/234092A1 |
The invention relates to a method for producing aminobenzoic acid or an aminobenzoic acid derivative using a fermentation process, in which (I) the aminobenzoic acid formed in the fermentation broth obtained by the fermentation is bound ...
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WO/2019/231159A1 |
The present application pertains to a modified homoserine dehydrogenase, and a method for producing a homoserine or a homoserine-derived L-amino acid using same.
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WO/2019/225475A1 |
The present invention provides a fermentation process capable of increasing the quantity of target substances due to microorganisms by efficiently switching over a fungus body growth phase and a substance production phase without using a...
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WO/2019/214084A1 |
Provided is a method for biocatalytic synthesis of Sitagliptin and intermediates thereof, in particular, provided are compounds of Formula (I) and Formula (II), or pharmaceutically acceptable salts thereof, a polypeptide capable of catal...
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WO/2019/211958A1 |
Provided is a method for improving the efficiency of production of an organic compound by a bacterium that does not inherently have an endogenous ED pathway. One embodiment pertains to a transformant of a coryneform bacterium obtained by...
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WO/2019/211127A1 |
The present invention relates to a polyurea coating composition comprising (A) a polyisocyanate; (B) a polyaspartic ester; and (C) an aspartic ester. The polyaspartic ester (B) is represented by the structure (I), where Z = a cycloalkyl,...
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WO/2019/213108A1 |
Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism...
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WO/2019/213028A1 |
Methods for increasing carbon-based chemical product yield in an organism by genetically modifying one or more genes involved in a stringent response and/or in a regulatory network, nonnaturally occurring organisms having increased carbo...
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WO/2019/211408A1 |
Provided is a method of modulating the trimethylamine (TMA) levels, odour and/or taste of an aquatic biological material, the method comprising contacting the aquatic biological material with a trimethylamine oxidase. Also provided are n...
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WO/2019/213019A1 |
Methods for increasing carbon-based chemical product yield in an organism by increasing carbon uptake and/or altering a pathway to or from an overflow metabolite in the organism, nonnaturally occurring organisms having increased carbon-b...
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WO/2019/213033A1 |
Methods of redirecting carbon flux and increasing C2/C3 or a C4/5/6 carbon chain length carbon-based chemical product yield in an organism, nonnaturally occurring organisms with redirected carbon flux and increased C2/C3 or C4/5/6 carbon...
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WO/2019/212052A1 |
The present invention provides a method for producing L-methionine by fermentation using a bacterium belonging to the genus Pantoea which has been modified to overexpress the rarD gene or a mutant gene thereof.
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WO/2019/213017A1 |
Methods for increasing carbon-based chemical product yield in an organism by perturbing redox balance in an organism as well as nonnaturally occurring organisms with perturbed redox balance and methods for their use in producing carbon-b...
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WO/2019/207812A1 |
This transformant obtained by introducing, to hydrogenophilus genus bacteria, DNA of (a1), (a2) or (a3), and (b) a gene of alcohol dehydrogenase, can efficiently produce isobutanol using carbon dioxide as the only source of carbon. DNA (...
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WO/2019/200874A1 |
Provided are a recombinant E. coli and the use thereof in the production of danshensu. The recombinant E. coli simultaneously expresses α-hydroxycarboxylic acid dehydrogenase, L-α-amino acid aminotransferase, and any one of glucose deh...
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WO/2019/198872A1 |
The present invention relates to a method for preparing an amino acid by decomposing protein components in a muscle part of a squid into amino acid components by using activation of a biotic enzyme of the squid caused by adding vitamin C.
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WO/2019/196262A1 |
The present invention relates to the field of pharmaceutical synthesis, and in particularly relates to a preparation method for a hexahydrofuro-furan-ol derivative, and an intermediate of the derivative and a preparation method therefor....
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WO/2019/198367A1 |
This invention provides a method for efficiently producing an N-acyl-amino group-containing compound using an enzymatic method. Specifically, this invention provides a method for producing an N-acyl-amino group-containing compound, inclu...
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WO/2019/192438A1 |
Provided herein are engineered decarboxylase polypeptides that are useful for catalyzing the decarboxylation of amino aicds such as L-tyrosine to produce tyramine or catalyzing the decarboxylation of L-DOPA to produce dopamine. Also prov...
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