| Document |
Document Title |
|
WO/2019/160301A1 |
The present application relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing aspartate-derived L-amino acids using same.
|
|
WO/2019/157921A1 |
Disclosed is a nitrilase mutant and an application thereof. The mutant is obtained by one or more substitutions of amino acids at position 201 or amino acid sequences at positions 324-381 of the amino acid sequence shown in SEQ ID No. 2....
|
|
WO/2019/160705A1 |
The invention provides a process for the preparation of a modified triethanolamine/fatty acid ester composition ratio by treatment of a conventional tnethanolamine fatty acid ester composition with a hydrolytic enzyme. Also provided are ...
|
|
WO/2019/160059A1 |
Provided is a method for recycling s-adenosylmethionine that is characterized in that after s-adenosylmethionine is demethylated, s-adenosylmethionine is regenerated by converting s-adenosylmethionine from methionine obtained by transfer...
|
|
WO/2019/124932A3 |
The present application pertains to a Corynebacterium sp. microorganism producing L-arginine and a method using the same for producing L-arginine.
|
|
WO/2019/154670A1 |
The present invention relates to recombinant Corynebacterium spp. host cells comprising, in relation to wild-type cells, at least one mutation selected from the group consisting of mutations that (i) reduce the activity of a protein, sel...
|
|
WO/2019/151769A1 |
The present disclosure relates to a method for preparing L-cysteine hydrochloride hydrate crystals, and L-cysteine hydrochloride hydrate crystals prepared by the method. Through the method for preparing L-cysteine hydrochloride hydrate c...
|
|
WO/2019/151770A1 |
The present disclosure relates to a method for preparing L-cysteine crystals, and L-cysteine crystals prepared by the method. Through the method for preparing L-cysteine crystals of the present disclosure, L-cysteine crystals can be obta...
|
|
WO/2019/147059A1 |
The present application relates to a microorganism of the genus Corynebacterium for producing an L-amino acid and a method for producing an L-amino acid by using the microorganism.
|
|
WO/2019/104179A4 |
This disclosure relates to deuterated D-serine, pharmaceutically acceptable salts thereof, analogs and prodrugs thereof, pharmaceutical compositions thereof, and methods of use.
|
|
WO/2019/140687A1 |
Disclosed in the present invention is a method for enzymatic synthesis of chloramphenicol intermediate. In the method, nitrobenzaldehyde and glycine are used as substrates, and are reacted under the catalysis of aldolase to obtain a chlo...
|
|
WO/2019/136585A1 |
Provided in the disclosure relates to microorganisms genetically modified to overexpress biofilm dispersal related polypeptides to enhance the production of lysine and lysine derivatives by the microorganism, method of generating such mi...
|
|
WO/2019/137083A1 |
Disclosed in the present invention are a one-step process for producing a nylon 5X salt and a prepared high-purity nylon 5X salt. The process comprises: subjecting a lysine fermentation liquid to ion exchange and desorption to obtain a p...
|
|
WO/2019/132549A1 |
The present invention relates to a method for preparing choline alfoscerate, usable as a food raw material, from phosphatidylcholine or lecithin, and a choline alfoscerate preparation method according to the present invention uses a spec...
|
|
WO/2019/128894A1 |
Provided are amino acid sequences of engineered transaminase polynucleotide that are useful for asymmetrically synthesizing chiral amine compounds, and its preparation process and reaction process under industrial-relevant conditions. Al...
|
|
WO/2019/130723A1 |
The present invention provides a method for producing glycine or a salt thereof by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein having L-threonine 3-dehydrogenase activity and a gene encodi...
|
|
WO/2019/124932A2 |
The present application pertains to a Corynebacterium sp. microorganism producing L-arginine and a method using the same for producing L-arginine.
|
|
WO/2019/119614A1 |
Disclosed in the present invention is a method for synthesizing L-aspartic acid by means of the whole cell catalysis of maleic acid by coupling two enzymes, which relates to the field of bio-engineering. In the present invention, a recom...
|
|
WO/2019/125686A1 |
Described are methods for improving the production of the amino acids glutamate and lysine in submerged Corynebacterium culture comprising adding to a submerged Corynebacterium culture a non- enzymatic fraction of spent Trichoderma ferme...
|
|
WO/2019/121876A1 |
The present invention relates to the production of organic acids by anaerobic fermentation of molasses and/or pulp, residues of the sugar industry, in which the molasses and/or the pulp are fermented in an aqueous medium containing vinasse.
|
|
WO/2019/123311A1 |
Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention ar...
|
|
WO/2019/118548A1 |
This disclosure provides engineered strains of Corynebacteria for the cost-effective production of lysine, tools and methods used to produce the engineered strains, and methods of using the engineered strains to produce lysine.
|
|
WO/2019/078528A3 |
Provided is a method for purifying 1,5-diaminopentane, the method comprising the steps of: preparing a fermentation broth comprising a carbonate of 1,5-diaminopentane; heating the fermentation broth to prepare a first composition; evapor...
|
|
WO/2019/104518A1 |
Provided microorganisms genetically modified to overexpress an imine/enamine deaminase to enhance the production of lysine and lysine derivatives by the microorganism. Also provided a method of generating such microorganism, and methods ...
|
|
WO/2019/104179A1 |
This disclosure relates to deuterated D-serine, pharmaceutically acceptable salts thereof, analogs and prodrugs thereof, pharmaceutical compositions thereof, and methods of use.
|
|
WO/2019/097123A1 |
The present invention relates to a process for producing aqueous acrylamide solution by hydrating acrylonitrile in an aqueous solution in the presence of a biocatalyst. The present invention further relates to aqueous acrylamide solution...
|
|
WO/2019/095161A1 |
A transaminase mutant and an application thereof, the amino acid sequence of the transaminase mutant is an amino acid sequence in which the amino acid sequence as represented by SEQ ID NO: 1 is mutated, the mutated amino acid position be...
|
|
WO/2019/096727A1 |
The invention relates to the biotechnological production of tryptophan and derivatives thereof. The invention provides means for an enhanced microbial L-tryptophan synthesis. In one aspect the invention provides a bacterial cell being ge...
|
|
WO/2019/096973A1 |
The present invention relates to a method for preparing an amino salt compound comprising: i) providing a carbonyl compound; ii) reacting the carbonyl compound provided according to (i) in the presence of a transaminase with ii-a) at lea...
|
|
WO/2019/096677A1 |
A microbiological process for the preparation of amides from the corresponding nitriles by enzymatic hydrolysis with nitrile hydratase enzyme from a bacterial strain of Rhodococcus biphenylivorans species is described.
|
|
WO/2019/091366A1 |
Disclosed is a method for preparing an optically pure L-tertiary leucine by using an active inclusion body, the method comprising the following steps: (1) preparing a bifunctional enzyme active inclusion body, wherein the active ingredie...
|
|
WO/2019/092054A1 |
Described is a novel micro-organism, having a nitrite tolerance of at least 200 mg/l and a nitrite clearance rate of at least 100 mg/l/d nitrite, as well as a method for the preparation of a monoculture of a micro-organism having such ni...
|
|
WO/2019/094752A1 |
This disclosure provides a non-genetic, high-throughput method of introducing and assaying effects of amino acid substitutions at a plurality of positions in a target protein. Mistranslation events are imposed stochastically during the t...
|
|
WO/2019/085445A1 |
A recombinant bacterium for producing L-lysine, a construction method thereof, and a method for producing L-lysine by using the recombinant bacterium. The recombinant bacterium has increased expression and/or activity of asparaginase com...
|
|
WO/2019/084950A1 |
Disclosed are a transaminase mutant and a use thereof. The amino acid sequence of the transaminase mutant is obtained by the mutation of the amino acid sequence as shown in SEQ ID NO: 1, and the mutation at least comprises one of the fol...
|
|
WO/2019/081004A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081319A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081318A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide obtained by hydrolyzing acrylonitrile in water in the presence of a biocatalyst capable of converting acrylonitrile...
|
|
WO/2019/081008A1 |
The present invention relates to methods for preparing aqueous acrylamide solutions having a low acrylic acid concentration, aqueous acrylamide solutions obtainable by such methods, and acrylamide homopolymers or copolymers obtainable by...
|
|
WO/2019/081331A1 |
The present invention relates to methods for preparing aqueous acrylamide solutions having a low acrylic acid concentration, aqueous acrylamide solutions obtainable by such methods, and acrylamide homopolymers or copolymers obtainable by...
|
|
WO/2019/081327A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/004779A3 |
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.
|
|
WO/2019/081323A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081330A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081321A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081320A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/081003A1 |
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...
|
|
WO/2019/078528A2 |
Provided is a method for purifying 1,5-diaminopentane, the method comprising the steps of: preparing a fermentation broth comprising a carbonate of 1,5-diaminopentane; heating the fermentation broth to prepare a first composition; evapor...
|
|
WO/2019/071668A1 |
Provided is an L-homoserine producing strain, which has a single and stable chromosome and does not contain any plasmids or other free DNA vectors. One or more genes related with L-threonine synthesis on the chromosome DNA are knocked ou...
|
|
WO/2019/073035A1 |
The present invention relates to methods for increasing the concentration of anthranilic acid tolerated by a given microbial cell by limiting the concentration of ammonia in the culture medium.
|
