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Patent Searching and Data


Matches 1 - 50 out of 11,116

Document Document Title
WO/2019/160301A1
The present application relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing aspartate-derived L-amino acids using same.  
WO/2019/157921A1
Disclosed is a nitrilase mutant and an application thereof. The mutant is obtained by one or more substitutions of amino acids at position 201 or amino acid sequences at positions 324-381 of the amino acid sequence shown in SEQ ID No. 2....  
WO/2019/160705A1
The invention provides a process for the preparation of a modified triethanolamine/fatty acid ester composition ratio by treatment of a conventional tnethanolamine fatty acid ester composition with a hydrolytic enzyme. Also provided are ...  
WO/2019/160059A1
Provided is a method for recycling s-adenosylmethionine that is characterized in that after s-adenosylmethionine is demethylated, s-adenosylmethionine is regenerated by converting s-adenosylmethionine from methionine obtained by transfer...  
WO/2019/124932A3
The present application pertains to a Corynebacterium sp. microorganism producing L-arginine and a method using the same for producing L-arginine.  
WO/2019/154670A1
The present invention relates to recombinant Corynebacterium spp. host cells comprising, in relation to wild-type cells, at least one mutation selected from the group consisting of mutations that (i) reduce the activity of a protein, sel...  
WO/2019/151769A1
The present disclosure relates to a method for preparing L-cysteine hydrochloride hydrate crystals, and L-cysteine hydrochloride hydrate crystals prepared by the method. Through the method for preparing L-cysteine hydrochloride hydrate c...  
WO/2019/151770A1
The present disclosure relates to a method for preparing L-cysteine crystals, and L-cysteine crystals prepared by the method. Through the method for preparing L-cysteine crystals of the present disclosure, L-cysteine crystals can be obta...  
WO/2019/147059A1
The present application relates to a microorganism of the genus Corynebacterium for producing an L-amino acid and a method for producing an L-amino acid by using the microorganism.  
WO/2019/104179A4
This disclosure relates to deuterated D-serine, pharmaceutically acceptable salts thereof, analogs and prodrugs thereof, pharmaceutical compositions thereof, and methods of use.  
WO/2019/140687A1
Disclosed in the present invention is a method for enzymatic synthesis of chloramphenicol intermediate. In the method, nitrobenzaldehyde and glycine are used as substrates, and are reacted under the catalysis of aldolase to obtain a chlo...  
WO/2019/136585A1
Provided in the disclosure relates to microorganisms genetically modified to overexpress biofilm dispersal related polypeptides to enhance the production of lysine and lysine derivatives by the microorganism, method of generating such mi...  
WO/2019/137083A1
Disclosed in the present invention are a one-step process for producing a nylon 5X salt and a prepared high-purity nylon 5X salt. The process comprises: subjecting a lysine fermentation liquid to ion exchange and desorption to obtain a p...  
WO/2019/132549A1
The present invention relates to a method for preparing choline alfoscerate, usable as a food raw material, from phosphatidylcholine or lecithin, and a choline alfoscerate preparation method according to the present invention uses a spec...  
WO/2019/128894A1
Provided are amino acid sequences of engineered transaminase polynucleotide that are useful for asymmetrically synthesizing chiral amine compounds, and its preparation process and reaction process under industrial-relevant conditions. Al...  
WO/2019/130723A1
The present invention provides a method for producing glycine or a salt thereof by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein having L-threonine 3-dehydrogenase activity and a gene encodi...  
WO/2019/124932A2
The present application pertains to a Corynebacterium sp. microorganism producing L-arginine and a method using the same for producing L-arginine.  
WO/2019/119614A1
Disclosed in the present invention is a method for synthesizing L-aspartic acid by means of the whole cell catalysis of maleic acid by coupling two enzymes, which relates to the field of bio-engineering. In the present invention, a recom...  
WO/2019/125686A1
Described are methods for improving the production of the amino acids glutamate and lysine in submerged Corynebacterium culture comprising adding to a submerged Corynebacterium culture a non- enzymatic fraction of spent Trichoderma ferme...  
WO/2019/121876A1
The present invention relates to the production of organic acids by anaerobic fermentation of molasses and/or pulp, residues of the sugar industry, in which the molasses and/or the pulp are fermented in an aqueous medium containing vinasse.  
WO/2019/123311A1
Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention ar...  
WO/2019/118548A1
This disclosure provides engineered strains of Corynebacteria for the cost-effective production of lysine, tools and methods used to produce the engineered strains, and methods of using the engineered strains to produce lysine.  
WO/2019/078528A3
Provided is a method for purifying 1,5-diaminopentane, the method comprising the steps of: preparing a fermentation broth comprising a carbonate of 1,5-diaminopentane; heating the fermentation broth to prepare a first composition; evapor...  
WO/2019/104518A1
Provided microorganisms genetically modified to overexpress an imine/enamine deaminase to enhance the production of lysine and lysine derivatives by the microorganism. Also provided a method of generating such microorganism, and methods ...  
WO/2019/104179A1
This disclosure relates to deuterated D-serine, pharmaceutically acceptable salts thereof, analogs and prodrugs thereof, pharmaceutical compositions thereof, and methods of use.  
WO/2019/097123A1
The present invention relates to a process for producing aqueous acrylamide solution by hydrating acrylonitrile in an aqueous solution in the presence of a biocatalyst. The present invention further relates to aqueous acrylamide solution...  
WO/2019/095161A1
A transaminase mutant and an application thereof, the amino acid sequence of the transaminase mutant is an amino acid sequence in which the amino acid sequence as represented by SEQ ID NO: 1 is mutated, the mutated amino acid position be...  
WO/2019/096727A1
The invention relates to the biotechnological production of tryptophan and derivatives thereof. The invention provides means for an enhanced microbial L-tryptophan synthesis. In one aspect the invention provides a bacterial cell being ge...  
WO/2019/096973A1
The present invention relates to a method for preparing an amino salt compound comprising: i) providing a carbonyl compound; ii) reacting the carbonyl compound provided according to (i) in the presence of a transaminase with ii-a) at lea...  
WO/2019/096677A1
A microbiological process for the preparation of amides from the corresponding nitriles by enzymatic hydrolysis with nitrile hydratase enzyme from a bacterial strain of Rhodococcus biphenylivorans species is described.  
WO/2019/091366A1
Disclosed is a method for preparing an optically pure L-tertiary leucine by using an active inclusion body, the method comprising the following steps: (1) preparing a bifunctional enzyme active inclusion body, wherein the active ingredie...  
WO/2019/092054A1
Described is a novel micro-organism, having a nitrite tolerance of at least 200 mg/l and a nitrite clearance rate of at least 100 mg/l/d nitrite, as well as a method for the preparation of a monoculture of a micro-organism having such ni...  
WO/2019/094752A1
This disclosure provides a non-genetic, high-throughput method of introducing and assaying effects of amino acid substitutions at a plurality of positions in a target protein. Mistranslation events are imposed stochastically during the t...  
WO/2019/085445A1
A recombinant bacterium for producing L-lysine, a construction method thereof, and a method for producing L-lysine by using the recombinant bacterium. The recombinant bacterium has increased expression and/or activity of asparaginase com...  
WO/2019/084950A1
Disclosed are a transaminase mutant and a use thereof. The amino acid sequence of the transaminase mutant is obtained by the mutation of the amino acid sequence as shown in SEQ ID NO: 1, and the mutation at least comprises one of the fol...  
WO/2019/081004A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081319A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081318A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide obtained by hydrolyzing acrylonitrile in water in the presence of a biocatalyst capable of converting acrylonitrile...  
WO/2019/081008A1
The present invention relates to methods for preparing aqueous acrylamide solutions having a low acrylic acid concentration, aqueous acrylamide solutions obtainable by such methods, and acrylamide homopolymers or copolymers obtainable by...  
WO/2019/081331A1
The present invention relates to methods for preparing aqueous acrylamide solutions having a low acrylic acid concentration, aqueous acrylamide solutions obtainable by such methods, and acrylamide homopolymers or copolymers obtainable by...  
WO/2019/081327A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/004779A3
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.  
WO/2019/081323A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081330A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081321A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081320A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/081003A1
Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein th...  
WO/2019/078528A2
Provided is a method for purifying 1,5-diaminopentane, the method comprising the steps of: preparing a fermentation broth comprising a carbonate of 1,5-diaminopentane; heating the fermentation broth to prepare a first composition; evapor...  
WO/2019/071668A1
Provided is an L-homoserine producing strain, which has a single and stable chromosome and does not contain any plasmids or other free DNA vectors. One or more genes related with L-threonine synthesis on the chromosome DNA are knocked ou...  
WO/2019/073035A1
The present invention relates to methods for increasing the concentration of anthranilic acid tolerated by a given microbial cell by limiting the concentration of ammonia in the culture medium.  

Matches 1 - 50 out of 11,116