Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 10,997

Document Document Title
WO/2019/055498A1
The present invention provides enzymes that have been optimized by implementation of Protein Repair One Stop Shop (PROSS), an algorithm that generates protein design(s) for enhanced stability without changing either enzymatic properties ...  
WO/2019/051069A1
The invention is directed to a process for producing one or more fermentation product in a multi-stage process including an inoculation reactor and at least one bioreactor. The inoculation reactor is fed a C1-containing gaseous substrate...  
WO/2019/048438A1
Method of obtaining a compound and corresponding apparatus. The method comprises adding a substrate (14) to a medium (132) comprised in a reactor (13, 33), and reacting the substrate in the reactor to form the compound. A first stream (1...  
WO/2019/043186A1
The present invention relates to a method for producinga chiral amine, performing a transamination reaction of a prochiral amino acceptor and an amino donor in a first solution in the presence of a transaminase, thereby forming a chiral ...  
WO/2019/039544A1
The present invention provides: a compound having a structure represented by general formula (1) (in the formula, n is 2-100, P represents a (C1-C5) alkylene group substituted with one amino group, Q is general formula (2) (in general fo...  
WO/2019/035612A1
The present application relates to a microorganism producing a mycosporine-like amino acid and a mycosporine-like amino acid production method using the same microorganism. Being enhanced in the productive potential of mycosporine-like a...  
WO/2019/031575A1
An enzyme having features (a) and (b). (a) Has D-amino acid reversible dehydrogenating activity. (b) Is a hexamer of a polypeptide having an amino acid sequence that identifies at least 80% with a SEQ ID No. 2 amino acid sequence.  
WO/2019/030808A1
Provided is a microorganism which is plasmid-free and has improved productivity. In one aspect, the present disclosure relates to a transgenic microorganism belonging to the genus Escherichia, in which at least five genes shown below are...  
WO/2019/031574A1
An enzyme having features (a) and (b). (a) Has D-amino acid reversible dehydrogenating activity. (b) Is a hexamer of a polypeptide having an amino acid sequence that identifies at least 80% with a SEQ ID No. 2 amino acid sequence.  
WO/2019/024706A1
An aspartase variant, a preparation method therefor, and an application thereof are provided. The amino acid sequence of the aspartase variant has 96% or higher identity with sequence 2 in the sequence listing, comprises T187I and N326C ...  
WO/2019/023796A1
Disclosed are methods for converting an alkaloid substrate compound into a N- alkylated alkaloid product compound in the presence of an alkyl donor compound and catalytic quantities of an N-alkyltransferase enzyme capable of converting t...  
WO/2019/027267A2
The present application relates to an ATP phosphoribosyltransferase (HisG) protein, and a histidine production method using same.  
WO/2019/022375A1
Provided are: an L-lysine-producing microorganism having been transformed with a polynucleotide comprising an L-lysine-inducible promoter; and a method for producing L-lysine by using the same.  
WO/2019/017706A2
The present application relates to a genus Corynebacterium microorganism producing putrescine and a method for producing putrescine using the same  
WO/2019/011236A1
Use of a stereoselective transaminase in the asymmetric synthesis of a chiral amine. In particular, provided is use of a polypeptide in the production of a chiral amine or a downstream product using a chiral amine as a precursor. Further...  
WO/2019/011946A1
The present invention relates to the field of bio-production of threonine. The inventors have conceived genetically modified yeasts, having an increased ability to produce threonine, as compared to the parent yeasts.  
WO/2019/012525A3
The present invention provides anti-microbial compositions comprising a hydroxycinnamic acid and related conjugates, analogues and derivatives, and methods of use thereof for enhancing production of anti-microbial agents in bacteria as w...  
WO/2019/012525A2
The present invention provides anti-microbial compositions comprising a hydroxycinnamic acid and related conjugates, analogues and derivatives, and methods of use thereof for enhancing production of anti-microbial agents in bacteria as w...  
WO/2019/013569A1
The present application relates to a microorganism expressing active D-proline reductase.  
WO/2019/011948A1
The present invention relates to the field of bio-production of metabolites, and in particular of metabolites produced by a microorganism using more particularly oxaloacetate as substrate or co-substrate upstream in the biosynthesis path...  
WO/2019/011942A1
The present invention relates to the field of bio -production of methionine and/or of its derivatives thereof, and in particular of bio-production of methionine and/or of its derivatives thereof from a reduced source of sulfur, such as M...  
WO/2019/011945A1
The present invention relates to the field of bio-production of metabolites, and in particular of metabolites produced by a microorganism using oxaloacetate, pyruvate and/or acetyl-CoA as substrate or co-substrate upstream in the biosynt...  
WO/2019/013532A2
The present application relates to a novel acetohydroxy acid synthetase mutant, and a method for producing a microorganism comprising the same or an L-branched chain amino acid using the same.  
WO/2019/011194A1
A bio-enzyme for catalyzing synthesis of phosphatidylserine, a preparation method therefor and application thereof. The bio-enzyme is an amino acid sequence represented by SEQ ID NO: 2. The preparation of the bio-enzyme comprises: first ...  
WO/2019/006700A1
Provided are a Bacillus subtilis strain JSC-137 producing 5-hydroxytryptophan and a method for producing 5-hydroxytryptophan by using the same with tryptophan as a substrate. The Bacillus subtilis strain JSC-137 has a collection number o...  
WO/2019/006701A1
A Bacillus licheniformis strain JSC-69 producing 5-hydroxytryptophan and having a collection number of CGMCC NO: 13533 and a method for producing 5-hydroxytryptophan by using the Bacillus licheniformis strain. The Bacillus licheniformis ...  
WO/2019/006723A1
Provided is a mesophilic microorganism host cell that produces lysine, and is genetically modified to express a thermophilic lysine decarboxylase and to overexpress one or more lysine biosynthesis polypeptides. And provided are methods o...  
WO/2019/008110A1
The present invention relates to the preparation of amines from aldehydes and ketones by reductive amination with enzymes having a reductive aminase activity on aldehydes and ketones devoid of any carboxyl group gamma of the carbonyl gro...  
WO/2019/004780A2
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.  
WO/2019/004778A2
The present application relates to an aspartokinase mutant, a microorganism including the mutant, and a method for production of an aspartate-derived L-amino acid or homoserine derivative, using the microorganicm.  
WO/2019/004234A1
The present invention addresses the problem of providing a simple method for producing ergothioneine. Provided is an ergothioneine production method characterized by comprising a step for culturing a microorganism belonging to the genus ...  
WO/2019/004779A2
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.  
WO/2018/230977A1
The present application relates to a novel polypeptide having an ability to discharge an ornithine-based product, and a method for producing an ornithine-based product using same.  
WO/2018/230978A1
The present application relates to a novel polypeptide having an ability to discharge an ornithine-based product, and a method for producing an ornithine-based product using same.  
WO/2018/229208A1
A method for producing a compound of formula (III) or a salt thereof, wherein said process comprises the following steps: (a) forming a mixture comprising a compound of formula (II) by adding an organocatalyst to a compound of formula (I...  
WO/2018/228247A1
Disclosed in the present application are a method for producing an enzymatic reaction by using adenosine to replace adenosine triphosphate (ATP) and an application thereof. The method comprises the following steps: (1) in an enzymatic re...  
WO/2018/220228A1
The method relates to the production of dialdehyde dioxime precursors corresponding to medium chain linear α-, ω-dinitriles by means of an enzymatic conversion.  
WO/2018/219107A1
Provided are engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed are developed through directed evolution based on ...  
WO/2018/219619A9
The invention relates to a method of producing a modified non-ribosomal peptide, e.g. a modified microcystin and/or modified nodularin (together CA), comprising the steps of: a) growing a modified non-ribosomal peptide producing cyanobac...  
WO/2018/219619A1
The invention relates to a method of producing a modified non-ribosomal peptide, e.g. a modified microcystin and/or modified nodularin (together CA), comprising the steps of: a) growing a modified non-ribosomal peptide producing cyanobac...  
WO/2018/217168A1
This invention relates to the bioproduction of substituted or unsubstituted phenylacetaldehyde, 2-phenylethanol, phenylacetic acid or phenylethylamine by subjecting a starting material comprising glucose, L-phenylalanine, substituted L-p...  
WO/2018/212626A1
The present invention relates to a recombinant microorganism having an enhanced ability to produce heme, coproporphyrin III (Copro III), and uroporphyrin III (Uro III), and a method for producing heme, coproporphyrin III, and uroporphyri...  
WO/2018/213796A1
The disclosure relates to host cells having altered NADPH availability, allowing for increased production of compounds produced using NADPH, and methods of use thereof. NADPH availability is altered by one or more of: expressing an alter...  
WO/2018/211051A1
The present invention is directed to microbial production of nicotinamide mononucleotide using a genetically modified fungus.  
WO/2018/209563A1
Provided are CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. Methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mu...  
WO/2018/210359A1
The invention relates to pyruvate carboxylase and a pyruvate carboxylase-encoding DNA, a plasmid containing said DNA and a microorganism for the production thereof, and to methods for the production of products the biosynthesis of which ...  
WO/2018/206027A1
It has been determined that the yeast Kazachstania slooffiae, which occurs endemically in hog-gut, is capable of utilising a plurality of L-amino acids, peptone, ammonium sulfate or urea as an individual N-source and in so doing, does no...  
WO/2018/202688A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a method for providing a natural pistachio, a natural malty, a natural hone...  
WO/2018/202683A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a method for providing a natural malty, a natural tropic fruit, a natural c...  
WO/2018/202686A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a nnethod for providing a natural milky, a natural caramel, a natural pop-c...  

Matches 1 - 50 out of 10,997