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Matches 1 - 50 out of 10,940

Document Document Title
WO/2019/006700A1
Provided are a Bacillus subtilis strain JSC-137 producing 5-hydroxytryptophan and a method for producing 5-hydroxytryptophan by using the same with tryptophan as a substrate. The Bacillus subtilis strain JSC-137 has a collection number o...  
WO/2019/006701A1
A Bacillus licheniformis strain JSC-69 producing 5-hydroxytryptophan and having a collection number of CGMCC NO: 13533 and a method for producing 5-hydroxytryptophan by using the Bacillus licheniformis strain. The Bacillus licheniformis ...  
WO/2019/006723A1
Provided is a mesophilic microorganism host cell that produces lysine, and is genetically modified to express a thermophilic lysine decarboxylase and to overexpress one or more lysine biosynthesis polypeptides. And provided are methods o...  
WO/2019/008110A1
The present invention relates to the preparation of amines from aldehydes and ketones by reductive amination with enzymes having a reductive aminase activity on aldehydes and ketones devoid of any carboxyl group gamma of the carbonyl gro...  
WO/2019/004780A2
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.  
WO/2019/004778A2
The present application relates to an aspartokinase mutant, a microorganism including the mutant, and a method for production of an aspartate-derived L-amino acid or homoserine derivative, using the microorganicm.  
WO/2019/004234A1
The present invention addresses the problem of providing a simple method for producing ergothioneine. Provided is an ergothioneine production method characterized by comprising a step for culturing a microorganism belonging to the genus ...  
WO/2019/004779A2
The present application relates to an O-succinyl homoserine transferase mutant, a polynucleotide for coding same, a microorganism comprising the mutant, and a method for producing O-succinyl homoserine using the microorganism.  
WO/2018/230977A1
The present application relates to a novel polypeptide having an ability to discharge an ornithine-based product, and a method for producing an ornithine-based product using same.  
WO/2018/230978A1
The present application relates to a novel polypeptide having an ability to discharge an ornithine-based product, and a method for producing an ornithine-based product using same.  
WO/2018/229208A1
A method for producing a compound of formula (III) or a salt thereof, wherein said process comprises the following steps: (a) forming a mixture comprising a compound of formula (II) by adding an organocatalyst to a compound of formula (I...  
WO/2018/228247A1
Disclosed in the present application are a method for producing an enzymatic reaction by using adenosine to replace adenosine triphosphate (ATP) and an application thereof. The method comprises the following steps: (1) in an enzymatic re...  
WO/2018/220228A1
The method relates to the production of dialdehyde dioxime precursors corresponding to medium chain linear α-, ω-dinitriles by means of an enzymatic conversion.  
WO/2018/219107A1
Provided are engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed are developed through directed evolution based on ...  
WO/2018/219619A1
The invention relates to a method of producing a modified non-ribosomal peptide, e.g. a modified microcystin and/or modified nodularin (together CA), comprising the steps of: a) growing a modified non-ribosomal peptide producing cyanobac...  
WO/2018/217168A1
This invention relates to the bioproduction of substituted or unsubstituted phenylacetaldehyde, 2-phenylethanol, phenylacetic acid or phenylethylamine by subjecting a starting material comprising glucose, L-phenylalanine, substituted L-p...  
WO/2018/212626A1
The present invention relates to a recombinant microorganism having an enhanced ability to produce heme, coproporphyrin III (Copro III), and uroporphyrin III (Uro III), and a method for producing heme, coproporphyrin III, and uroporphyri...  
WO/2018/213796A1
The disclosure relates to host cells having altered NADPH availability, allowing for increased production of compounds produced using NADPH, and methods of use thereof. NADPH availability is altered by one or more of: expressing an alter...  
WO/2018/211051A1
The present invention is directed to microbial production of nicotinamide mononucleotide using a genetically modified fungus.  
WO/2018/209563A1
Provided are CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. Methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mu...  
WO/2018/210359A1
The invention relates to pyruvate carboxylase and a pyruvate carboxylase-encoding DNA, a plasmid containing said DNA and a microorganism for the production thereof, and to methods for the production of products the biosynthesis of which ...  
WO/2018/206027A1
It has been determined that the yeast Kazachstania slooffiae, which occurs endemically in hog-gut, is capable of utilising a plurality of L-amino acids, peptone, ammonium sulfate or urea as an individual N-source and in so doing, does no...  
WO/2018/202688A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a method for providing a natural pistachio, a natural malty, a natural hone...  
WO/2018/202683A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a method for providing a natural malty, a natural tropic fruit, a natural c...  
WO/2018/202686A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a nnethod for providing a natural milky, a natural caramel, a natural pop-c...  
WO/2018/202684A1
The present invention relates to a process for preparing a natural flavor base and a flavor base obtainable by such process. A further aspect of the invention is a method for providing a natural nutty, a natural roasty, and/or a natural ...  
WO/2018/197608A1
The present invention provides a method of producing astaxanthin and lysine in recombinant gram-positive bacteria comprising a nucleic acid sequence encoding for a crtZ-protein from F. pelagi and comprises a nucleic acid sequenceencoding...  
WO/2018/190398A1
According to the present invention, it becomes possible to produce theanine with high efficiency without requiring adding ethylamine from the outside and without accumulating or remaining ethylamine as a by-product, by using a microorgan...  
WO/2018/185084A1
The present invention relates to a method of producing vinylglycine and/or derivatives thereof, the method comprising, - contacting glutamic acid and/or derivatives thereof with an electrolysis medium; and - subjecting the glutamic acid ...  
WO/2018/181774A1
The purpose of the present invention is to provide a novel enzymatic protein that makes it possible to produce an optically active β-hydroxy amino acid. The present invention solves the aforementioned problem by providing a monooxygenas...  
WO/2018/182361A1
The present invention relates to a method for preparing a bacteria mutant strain, comprising the steps of: (a) primarily transforming a normal bacteria into an enzyme-expressing vector which has temperature sensitivity or antibiotic sens...  
WO/2018/171488A1
Provided is a method for screening a corynebacterium constitutive expression vector promoter on the basis of transcriptome sequencing; and further provided are the corynebacterium constitutive expression vector promoter screened on the b...  
WO/2018/168525A1
The present invention provides a polyamine-rich yeast mutant that is mutated in comparison to the Sake yeast kyokai No. 7 in that, in the amino acid sequence of any one of leucine synthase, aconitic acid synthase, S-adenosyl-L-methionine...  
WO/2018/165325A1
Provided herein are methods for producing an organoboron product. The methods include combining a boron-containing reagent and a carbene precursor in the presence of a heme protein, e.g., a cytochrome c, a cytochrome P450, a globin, a pr...  
WO/2018/157942A1
Process of cell-free synthesis of a target protein, comprising at least the following steps: a. providing at least one precursor of an amino-acid, a cell-free extract comprising means for transforming said precursor of an amino-acid into...  
WO/2018/160103A1
A group of inventions relates to biotechnology, in particular a method for producing L-asparaginic acid. For this purpose, a recombinant strain of Escherichia coli that produces aspartase was produced by introducing a recombinant plasmid...  
WO/2018/152918A1
Provided is an L-homoserine-producing bacterial strain. One or more genes of the bacterial strain related to an L-homoserine metabolic pathway are knocked out or weakened, and/or one or more genes related to the L-homoserine metabolic pa...  
WO/2018/144965A1
Microorganisms and bioprocesses are provided that convert gaseous substrates, such as renewable H2 and waste CO2 producer gas, or syngas into high-protein biomass that may be used directly for human nutrition, or as a nutrient for plants...  
WO/2018/127143A1
The invention provides a highly active S-cyanohydrin lyase obtained by mutating an amino acid residue at position 103 of a wild-type cassava S-cyanohydrin lyase. The mutation can significantly increase an expression of a mutant enzyme in...  
WO/2018/124440A3
The present application relates to novel mutant polypeptide having isopropylmalate synthase activity, a polynucleotide coding for the same, a microorganism including the polypeptide, and a method for producing L-leucine by culturing the ...  
WO/2018/124440A2
The present application relates to novel mutant polypeptide having isopropylmalate synthase activity, a polynucleotide coding for the same, a microorganism including the polypeptide, and a method for producing L-leucine by culturing the ...  
WO/2018/124247A1
A nitrile hydratase that is derived from Pseudonocardia thermopila and has an α subunit and a β subunit, wherein a specific amino acid residue has been substituted for the amino acid residue in at least one position selected from the g...  
WO/2018/124475A2
The present invention relates to a recombinant microorganism having a xenogeneic gene introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention prov...  
WO/2018/120025A1
The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms gene...  
WO/2018/124475A3
The present invention relates to a recombinant microorganism having a xenogeneic gene introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention prov...  
WO/2018/122511A1
The invention relates to the field of organic polysulphides, more particularly to a method for synthetising functionalised organic polysulphides of formula (I): R2-X-(NR1R7)C*H-(CH2)n-Sa-(CH2)n-C*H(NR1R7)-X-R2, in which the various subst...  
WO/2018/124778A1
The present application relates to a microorganism producing O-phosphoserine and a method for producing O-phosphoserine, cysteine or a cysteine derivative using same.  
WO/2018/124533A1
The present application relates to a Corynebacterium sp. microorganism for producing L-lysine and a method for producing L-lysine by using the same.  
WO/2018/120026A1
The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms gene...  
WO/2018/116203A1
The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, ...  

Matches 1 - 50 out of 10,940