| Document |
Document Title |
|
WO/2018/199814A1 |
The invention relates to microbiology and biotechnology. The unicellular algae strain Mallomonas kalinae SX-1 VKPM AI-23, a producer of fucoxanthin, a carotenoid having antioxidant activity, has been deposited at the Federally Funded Ins...
|
|
WO/2018/200888A1 |
The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing...
|
|
WO/2018/183706A1 |
The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (,S)-Y-hydroxymethyl-a,P-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the inv...
|
|
WO/2018/172401A1 |
The invention relates to fungal cells for the production of FDCA. The fungal cell has genetic modification that reduces specific 2,5-furandicarboxylic acid (FDCA) decarboxylating monooxygenase activity in the cell, as compared to a corre...
|
|
WO/2018/169055A1 |
It is known that foods containing a carbohydrate, e.g., starch, in a large amount generate acrylamide upon heating at high temperatures. Some documents state that acrylamide is formed by the Maillard reaction of an amino acid, e.g., aspa...
|
|
WO/2018/159957A1 |
The present invention relates to a method for selective and effective synthesis of equol, dehydroequol, 5-hydroxy-equol, and 5-hydroxy-dehydroequol from daidzein or genistein, using recombinant Escherichia coli bacteria in which Slackia ...
|
|
WO/2018/154048A1 |
The invention provides an improved method of isolating the 3-(E)-isomer of an unsaturated carboxylic acid from a mixture of corresponding (E/Z)isomers. More particularly, the present invention relates to an improved method for the biocat...
|
|
WO/2018/157021A1 |
A Squalene Hopene Cyclase (SHC) isolated from Gluconobacter morbifer is provided as are variants and a method for using the G. morbifer SHC to biocatalytxcally convert homofarnesol to ambroxan.
|
|
WO/2018/149282A1 |
Disclosed is a method for heterologous expression of an epothilone, comprising introducing an epothilone gene cluster into host bacteria, while supplementing an epothilone precursor synthesis pathway combining with the introduction of th...
|
|
WO/2018/148848A1 |
A method and cell line for producing phytocannabinoids and phytocannabinoid analogues in yeast. The method applies, and the cell line includes, a yeast cell transformed with a polyketide synthase CDS and a cytosolic prenyltransferase CDS...
|
|
WO/2018/145342A1 |
Disclosed in the present invention is a method for preparing dihydrodaidzein, comprising the following steps: (1) using the compound represented by formula I as a raw material for an oxidation reaction to prepare a compound represented b...
|
|
WO/2018/142109A1 |
The present invention relates to a process of producing a monoterpene and/or derivatives thereof. The process comprises the steps of: a) providing a host microorganism genetically engineered to express a bacterial monoterpene synthase (m...
|
|
WO/2018/136654A1 |
Disclosed herein are methods for N-demethylating an N-methylated compound using an enzymatic reaction, rather than, e.g. a chemical modification. Also provided herein are enzymes for performing the reaction.
|
|
WO/2018/133114A1 |
A novel 2, 2' -bipyridyl oxime, kibdelomycin A was isolated from the broth culture of a rare actinomycete strain Kibdelosporangium phytohabitans XY-R10. Its structure was established by extensive 1D and 2D NMR and high-resolution mass sp...
|
|
WO/2018/130682A1 |
The present application provides a safe, efficient, environmental friendly and convenient method for an enzyme assisted lipid-based extraction and stabilization of phyto-cannabinoids and terpenes/terpenoids from plant materials. The lipi...
|
|
WO/2018/126610A1 |
A genetically engineered bacterium for producing tetrahydropyrimidine by induction using xylose, a construction method therefor, and an application thereof. The strain is obtained by heterologously expressing an ectABC gene cluster from ...
|
|
WO/2018/122510A1 |
The invention relates to a method for synthetising functionalised cyclic dithiocarbamates of formula (I), in which the various substituents are as defined in the description, by reacting a compound of formula (II): G-(CH2)n-C*H(NHR1)-X-R...
|
|
WO/2018/123467A1 |
An indoloquinazoline compound represented by a specific structure. Clones having exceptional AI activity were detected by metagenomic analysis, and a novel indoloquinazoline compound synthase was identified from the clones. The novel ind...
|
|
WO/2018/124135A1 |
The present invention addresses the problem of providing a method for eliminating the hydroxyl group at the 9-position of an urolithin in order to produce another urolithin. This problem is solved by a method for producing a second uroli...
|
|
WO/2018/113476A1 |
The present invention provides a genetically engineered bacterium of coexpressing cyclohexanone monooxygenase and isopropanol dehydrogenase and use thereof, and the genetically engineered bacterium constructed can catalyze and convert hi...
|
|
WO/2018/110799A1 |
Provided are a compound represented by any one of chemical formulas 1 to 3, or an isomer, derivative, solvate, or pharmaceutically acceptable salt thereof, a production method therefor, and a use thereof. According to this, antibacterial...
|
|
WO/2018/103409A1 |
Disclosed are a methylocystis and the use thereof in the selective resolution and preparation of (S)-α-ethyl-2-oxo-1-pyrrolidine acetates. After cell immobilization of the enzyme-producing methylocystis, the methylocystis is applied to ...
|
|
WO/2018/091885A1 |
The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 3, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound.
|
|
WO/2018/090891A1 |
Disclosed are a dipyridyl alkaloid, a preparation method therefor and a use thereof, the structure of the dipyridyl alkaloid is as shown in formula I. The dipyridyl alkaloid has a tumour cell proliferation inhibitory activity and can be ...
|
|
WO/2018/079686A1 |
A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective ...
|
|
WO/2018/075670A1 |
A method of demethylizing an opioid to a nor-opioid is provided. The method comprises contacting an opioid with at least one enzyme. Contacting the opioid with the at least one enzyme converts the opioid to a nor-opioid. A method of conv...
|
|
WO/2018/074916A1 |
The present invention is in the field of production of carbapenem antibiotics by microorganisms, specifically bacteria. The present invention relates to an improved method for producing high levels of antibiotics, and specifically carbap...
|
|
WO/2018/046104A1 |
The present invention relates to microorganisms or progeny thereof having biosynthetic capability to convert cycloalkanes and to produce lactones using complex composed of cytochrome P450 monooxygenase, two reductases ferredoxin (Fd) and...
|
|
WO/2018/040372A1 |
Provided are a yeast and a method for catalyticaly synthesizing 2,5-dihydroxymethylfuran by using the same. The yeast is Meyerozyma guilliermondii SC 1103 deposited in the China Center for Type Culture Collection with CCTCC NO.M 2016144....
|
|
WO/2018/042841A1 |
A SAMe-containing material having a high SAMe content can be obtained by a method which comprises: a heating/dissolving step for supplying water and brown sugar to a culture tank and dissolving the brown sugar by heating; a culture step ...
|
|
WO/2018/036479A1 |
A genetically engineered strain of phenazine-1-carboxamide (PCN), a preparation method for same, and uses thereof. The genetically engineered strain specifically is a genetically engineered strain produced by knocking off either or both ...
|
|
WO/2018/035249A1 |
The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.
|
|
WO/2018/029338A1 |
A process for producing the gardenia blue pigment comprising treating geniposide with a glycosidase to obtain a hydrolysate, extracting the hydrolysate with a solvent and removing the solvent after the extraction to obtain a product comp...
|
|
WO/2018/029282A1 |
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductases thereby increasing the production of benzylisoqui...
|
|
WO/2018/015512A1 |
The invention relates to recombinant microorganisms and methods for producing 13R-MO and/or 13R-MO derivatives, including forskolin.
|
|
WO/2018/012426A1 |
Provided is a method for efficiently producing mucic acid from a commonly used organic raw material such as glucose or galactose. Provided is a method for producing mucic acid in which glucose or galactose is used as a starting material ...
|
|
WO/2018/005806A2 |
The present disclosure relates to biosynthetic pathways for producing flavor and fragrance chemicals, such as green notes including trans-2-unsaturated aldehydes and lactones. The present disclosure provides methods for producing trans-2...
|
|
WO/2018/000089A1 |
Polynucleotides and polypeptides useful in the manufacture of a class of chemical compounds known as alkaloids are provided. The polynucleotides and polypeptides may be used to synthesize alkaloids, including reticuline, thebaine and mor...
|
|
WO/2018/002379A2 |
The invention relates to use of a peroxygenase for preparing indigo dyes and an in situ method for dyeing a textile with indigo dyes.
|
|
WO/2017/214159A1 |
The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.
|
|
WO/2017/213758A1 |
The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered prolin...
|
|
WO/2017/202897A1 |
Described herein are variants of acetylserotonin O-methyltransferase (ASMT) as well as vectors and recombinant microbial host cells expressing such ASMT variant and their use in producing melatonin and related compounds. Preferred ASMT v...
|
|
WO/2017/202193A1 |
Provided are applications of a recombinant ketoreductase in the preparation of (R)-3-quinuclidinol. The amino acid sequence of the recombinant ketoreductase is shown by any one of SEQ ID No.2, 4, 6, 8 and 10. A product is obtained in a r...
|
|
WO/2017/203454A1 |
The invention relates to a method for obtaining an extract from a cell culture of Neem (Azadirachta indica). The suspended cell culture is subjected to cellular stress under conditions that promote the production of active metabolites su...
|
|
WO/2017/197993A1 |
Provided are a Serratia liquefaciens ZMT-1 the collection No. of which is CCTCC NO:M2016170, and a method for producing Heliotropin by using the Serratia liquefaciens ZMT-1 strain or an enzyme produced by the Serratia liquefaciens ZMT-1 ...
|
|
WO/2017/182542A1 |
A solid form of (-)-Ambrox formed by a bioconversion process.
|
|
WO/2017/178624A1 |
The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with a...
|
|
WO/2017/175064A1 |
A method for the bio-enzymatic synthesis of tetrahydrocannabivarin (THC-v), cannabivarin (CBV) and cannabinol (CBN) by contacting a compound according to Formula I with a cannabinoid synthase enzyme. The cannabinoids are produced in the ...
|
|
WO/2017/167866A1 |
Described herein are recombinant microbial host cells comprising biosynthetic pathways and their use in producing oxidation products and downstream products, e.g., melatonin and related compounds, as well as enzyme variants, nucleic acid...
|
|
WO/2017/165692A1 |
The present disclosure provides compounds linked with a saccharide-metal complex. The compounds are designed to protect organs by inducing acquired cytoresistance without causing injury to the organ, among other potential uses.
|
