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Matches 551 - 600 out of 7,918

Document Document Title
WO/2006/070775A1
A process for the production of D-firefly luciferin or luminescent derivatives thereof, characterized by reacting an L-firefly luciferin raw material containing at least one member selected from the group consisting of (1) esters of L-fi...  
WO/2006/067535A1
Abstract The present invention relates to a novel source of microorganism for production of Camptothecin and related camptothecinoids. The invention also discloses its isolation, screening for Camptothecin production, growth, fermentatio...  
WO2005116061A3
The invention relates to DNA sequences coding for polypeptides which, in turn, participate in the enzymatic biosynthesis of polyketide compounds, and to amino acid sequences of said polypeptides. The invention also relates to the use of ...  
WO2005086907A3
Domains of ambruticin polyketide synthase and modificationenzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin ana...  
WO/2006/065767A3
Improved catalytic enzyme preparations are provided which effectively catalyze reactions carried out inorganic solvents. The preparations comprise nanoscale solid support particles (e.g., fumed silica or alumina) having enzyme molecules ...  
WO2006015716A3
The invention relates to a method for producing chiral, non-racemic, cis-configured cyclohexanols or cyclohexanol derivatives of formulae (la) and (Ib) wherein the radicals have the designations cited in the description, by means of enzy...  
WO2005121327A3
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described. Also provided are novel Streptomyces species and metho...  
WO/2006/066147A3
Antifungal compounds represented by formula I where R1, R2, R3 and R4 are as defined herein. Isolated or purified naturally occurring 20,21-dihydro ambruticin compounds. The invention also provides Sorangium cellulosum ambM, ambO, ambP, ...  
WO/2006/063055A3
Disclosed are detoxifying enzyme conjugates, including conjugates of variants of such detoxifying enzymes. The detoxifying enzymes are preferably chlolinesterases, and more preferably , butyrylcholinesterase. Also disclosed are methods o...  
WO/2006/061425A2
The present invention describes the transformation of a microorganism that does not naturally produce a beta-lactam compound with polynucleotides involved in the biosynthesis of beta-lactam compounds and the use of such transformed micro...  
WO/2006/059400A1
A microorganism (Penicillium sp. FKI-2140, FERM ABP-10165), which belongs to fungi and is capable of producing antibiotics FKI-2140 (FKI-2140A1 or A2, and/or FKI-2140B, and/or FKI-2140C, and/or FKI-2140D, and/or FKI-2140E, and/or FKI-214...  
WO2006032232A3
The invention relates to novel genes from lysolipin-producing microorganisms, to novel gene clusters formed from novel and/or known genes of these microorganisms, to expression products of these genes, to a transformation vehicle contain...  
WO/2006/060803A3
Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes mono-deacetylating, polymerizing and deacetylating an aryl monomer represented by the fo...  
WO/2006/057341A1
After culturing for a definite period of time, a mutant of wild type Escherichia coli, which has a chromosomal DNA shorter by 470 kbp or more than the chromosomal DNA of the wild type, shows a larger cell count than the wild type. Theref...  
WO2005019426A3
Domains of fostriecin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare fostriecin in pharmaceutically useful quantities are described, as are methods to prepare fostriecin an...  
WO/2006/054500A1
[PROBLEMS] To provide a methylated catechin synthase gene by which methylated catechin having a high antiallergic activity can be efficiently biosynthesized. [MEANS FOR SOLVING PROBLEMS] A gene encoding an enzyme capable of biosynthesizi...  
WO/2006/055528A2
The present disclosure provides enzymatic methods for generating stereoisomerically pure products by resolving a racemic mixture of N-protected β-lactams with a lipase from Candida antarctica with high stereospecificity. The presence of...  
WO/2006/047891A1
This invention relates to novel biologically active polycyclic aromatics produced by cultivation of Micromonospora echinospora ssp. challisensis NRRL 12255. The invention also relates to their pharmaceutically acceptable salts, prodrugs ...  
WO/2006/048551A1
The inventive method for stereoselectively preparing a (R) or (S) gamma-lactone consists in microbially biosynthesising gamma-lactone, wherein said biosynthesis is carried out from a substrate selected from C5 to C20 fatty acids with the...  
WO/2006/048947A1
Macrophage foaming inhibitor FKI-1840, and a process for producing the same, comprising incubating a microbe belonging to the genus Phoma which is capable of producing the substance FKI-1840 (Phoma sp. FKI-1840, FERM ABP-10150) in a cult...  
WO/2006/048550A1
The invention relates to a gamma-undecenolactone of formula (i), wherein a lactonic cycle can carry an unsaturation between carbon N°2 and carbon N°3 and is preferably saturated, RI is a possibly substituted C7 alkenyl or alkynyl group...  
WO/2006/046130A2
The invention relates to a process for the preparation of pure pravastatin or a salt thereof using adsorption matrices. The invention also relates to pharmaceutical compositions that include the pure pravastatin and the use of the compos...  
WO2006031661A3
Although macrolide compounds are insoluble in water, surprisingly high part of the product was found in the liquid phase of the fermentation broth. Therefore, processing the entire fermentation broth, i.e. the suspension obtained by cult...  
WO/2006/046314A1
Microbe (Penicillium citrinum FKI-1938, FERM ABP-10149) belonging to the genus Penicillium citrinum and capable of producing substance FKI-1938A and/or substance FKI-1938B and/or substance FKI-1938B’ and/or substance FKI-1938C is incub...  
WO/2006/046152A2
The invention provides a method for the heterologous expression of a secondary metabolite encoded by a biosynthetic pathway. Also provided is a method for introducing a large sized DNA molecule into the chromosome of a heterologous host ...  
WO2003066871A3
Isolated nucleic acid and amino acid sequences for phenylalanine aminomutase enzyme and methods for purifying this enzyme are provided. Methods for altering biosynthesis of compounds in plant cell cultures are also provided. In particula...  
WO/2006/038218A1
The present invention discloses the manufacture of MPA by fermentation under optimal fermentation parameters using a new strain of Penicillium arenicola.  
WO2005100569A3
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, v...  
WO/2006/034567A1
This invention relates to methods of inhibiting growth and/or proliferation of a neoplastic cell, and methods of treating neoplasms using the farnesylated dibenzodiazepinone compound of Formula I. The invention includes pharmaceutical co...  
WO2005108590A3
The invention relates to a method for producing the optically active alkanols of formula (I), wherein n is an integer of from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, carbocy...  
WO2006015811A3
The invention relates to a dihydrocoumarin that has been technically produced by the biotransformation of coumarin and to associated production variants that are carried out with the aid of isolated enzymes and/or microorganisms. Pure co...  
WO/2006/035770A1
[PROBLEMS] To provide a process for synthesizing natural compound derivatives useful in random high-throughput screening (HTS), the search for drugs or agricultural chemicals, the search for lead compounds of drugs or agricultural chemic...  
WO2004081176A3
A method for biotransformation of organic compounds using non-prokaryotic microalgae is disclosed. The method is useful to biotransform a chemical precusor compound, preferably a heterocyclic compound, to a chemically distinct final prod...  
WO2004053065A3
Domains of disorazole polyketide synthase and polynucleotides encoding them are provided. Methods to prepare disorazoles in pharmaceutically useful quantities are described, as are methods to prepare disorazole analogs and other polyketi...  
WO/2006/032232A2
The invention relates to novel genes from lysolipin-producing microorganisms, to novel gene clusters formed from novel and/or known genes of these microorganisms, to expression products of these genes, to a transformation vehicle contain...  
WO/2006/031665A1
Mycophenolic acid can be isolated from fermentation broth easily with low consumption of organic solvents to produce mycophenolic acid that is surprisingly high in purity. The process can be accomplished by addition of a suitable base to...  
WO/2006/031661A2
Although macrolide compounds are insoluble in water, surprisingly high part of the product was found in the liquid phase of the fermentation broth. Therefore, processing the entire fermentation broth, i.e. the suspension obtained by cult...  
WO/2006/030909A1
A process for producing 2-hydroxy-4-substituted pyridines microbiologically; novel microbes; and novel compounds. Specifically, a process for the production of 2-hydroxy-4-substituted pyridines by making a microbe or a product of treatme...  
WO/2006/031008A1
The present invention provides a novel microorganism capable of metabolizing isoflavone. More particularly, the invention provides a novel microorganism capable of metabolizing daidzein and genistein into dihydrodaidzein and dihydrogenis...  
WO/2006/031007A1
The present invention provides a novel microorganism capable of metabolizing dihy- drodaidzein into equol. More particularly, the invention provides Eggerthella sp. microorganism capable of metabolizing dihydrodaidzein into equol under a...  
WO/2006/031664A1
The invention is a simple process for separation of tacrolimus and its analogues, ascomycin and tsucubamycin B and preparation of enough pure crystalline tacrolimus. The process takes advantage of surprising properties of tacrolimus and ...  
WO/2006/024582A1
The present invention relates to a process for the preparation of mycophenolate mofetil (MMF) in which an ester of mycophenolic acid (MPA) with a low-molecular- weight aliphatic alcohol is transesterif ied with N- (2- hydroxyethyl) morph...  
WO2005100587A3
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific 2,2-disubstituted epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polyp...  
WO2005100578A3
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vect...  
WO/2006/018211A1
The present invention relates to a process for the production of isoprenoids, in particular Coenzyme Q-10 by microorganisms. More particularly, the present invention relates to a process for increased production of Coenzyme Q-10 by micro...  
WO/2006/019209A1
The invention relates to a method and apparatus for compensating the lens shading phenomenon in image sensor. The invention first stores an inputted compensation reference value, identifies a center pixel using digital image signals rece...  
WO2004015119A3
This invention relates to processes for the preparation of ansamitocins, in particular ansamitocins that can be converted to maytansinol.  
WO/2006/015727A2
The invention relates to a method for producing, in essence, enantiomer-pure 3-hydroxycarboxylic acids or esters of general formula (III) by reacting racemic oxetan-2-ones of general formula (I) with compounds R3-OH of general formula (I...  
WO/2006/015811A2
The invention relates to a dihydrocoumarin that has been technically produced by the biotransformation of coumarin and to associated production variants that are carried out with the aid of isolated enzymes and/or microorganisms. Pure co...  
WO2005047509A8
The present invention relates to Mycobacterium ulceran virulence plasmid, pMUM001 and particularly to a cluster of genes carried by this plasmid that encode polyketide synthases (PKSs) and polyketide-modifying enzymes necessary and suffi...  

Matches 551 - 600 out of 7,918