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Matches 551 - 600 out of 8,317

Document Document Title
WO/2007/039816A2
The present invention relates to improved fermentation processes for the preparation of tacrolimus or a salt or derivative thereof by culturing a microorganism capable of producing tacrolimus or a salt or derivative thereof under submerg...  
WO/2007/035693A3
Novel isonitrile biosynthetic enzymes isnA and isnB which together possess a catalytic activity of converting an amine-containing compound to an isonitrile-containing compound are described. The genes that encode such enzymes, recombinan...  
WO/2007/030772A3
Genetically engineered Streptomyces clavuligerus strains with improved capabilities to produce clavulanic acid are provided. The strains are genetically engineered by disrupting newly identified glyceraldehyde-3-phosphate dehydrogenase (...  
WO/2007/028602A1
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the fu...  
WO/2007/028609A1
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the fu...  
WO/2007/030662A1
Disclosed are methods of modulating biosynthesis of Salinosporamide A and its analogs, which are useful in treating cancer, inflammatory conditions, and/or infectious disease. The methods involve, for example, genetic manipulation, selec...  
WO/2007/028239A2
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO/2007/028239A3
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO2006136521A8
A process is described for the preparation of escitalopram and the pharmaceutically acceptable salts thereof starting from 5-cyanophthalide by a process which provides an enantioselective enzymatic deacylation reaction of a complex of th...  
WO2006134623B1
The present invention describes a method for increasing the survival of the bacteria of Rhizobium genus, comprising the steps of: making the bacteria to grow in a chemically defined medium; keeping the bacteria in growth stationary phase...  
WO/2007/018194A1
It is intended to provide a method for producing cercosporamide, characterized by culturing a bacterium belonging to the genus Lachnum and/or a bacterium belonging to the genus Pseudaegerita and collecting cercosporamide from the culture...  
WO/2007/015511A1
A novel D-amino acid oxidase isolated and purified from Candida intermedia; a gene encoding the D-amino acid oxidase; a recombinant plasmid carrying the gene; a transformant having the D-amino acid oxidase gene introduced therein; a meth...  
WO/2007/014971A3
The invention relates to genes involved in the biosynthesis of thiocoraline and to the heterologous production of same. According to the invention, the cluster of genes responsible for the biosynthesis of thiocoraline was identified and ...  
WO/2007/014971A2
The invention relates to genes involved in the biosynthesis of thiocoraline and to the heterologous production of same. According to the invention, the cluster of genes responsible for the biosynthesis of thiocoraline was identified and ...  
WO2005118777A8
The invention relates to a novel strain Saccharothrix actinomycete SA 103 deposited at CNCM on 16th February 2004, number I-3160 or a mutant strain thereof; a method and a medium for selection of said strain; and a method for the product...  
WO/2007/010944A1
The invention relates to a method for producing an optically active 2-(N-substituted aminomethyl)-3-hydroxybutyric acid ester, characterized by allowing an enzyme source having an activity of stereoselectively reducing a 2-(N-substituted...  
WO/2007/007986A1
Provided is S-adenosylmethionine-6-N-lysine-methyltransferase obtained from Neυrospora crassa, a polynucleotide encoding the same, a vector and host cell containing the polynucleotide, and a method of producing trimethyllysine by cultur...  
WO/2007/007399A1
Compounds having an anti-MRSA activity and having a skeleton and action mechanism different from those of existing drugs, which are useful as a novel antimicrobial agent. Conventionally, vancomycin is used as a drug for MRSA. However, re...  
WO/2007/003574A1
A method for making dihydroxyacetone phosphate (DHAP) comprising treating dihydroxyacetone with a bacterial acid phosphatase in the presence of pyrophosphate. The invention further pertains to a method for making, preferably in one pot, ...  
WO/2007/001406A3
The present invention discloses novel compounds, compositions containing the compounds and methods for the treatment of viral infection, particularly hepatitis C and SARS. In particular the invention provides aryl-containing macrocyclic ...  
WO/2006/136521A1
A process is described for the preparation of escitalopram and the pharmaceutically acceptable salts thereof starting from 5-cyanophthalide by a process which provides an enantioselective enzymatic deacylation reaction of a complex of th...  
WO/2006/134623A1
The present invention describes a method for increasing the survival of the bacteria of Rhizobium genus, comprising the steps of: making the bacteria to grow in a chemically defined medium; keeping the bacteria in growth stationary phase...  
WO/2006/134482A1
A novel process for producing atrovastatin, pharmaceutically acceptable salts thereof, and intermediates thereof using an aldolase is described. Compounds so prepared are useful as inhibitors of the HMG-CoA reductase and may thus be used...  
WO/2006/134374A2
There is provided a method for producing L-ascorbic acid (vitamin C) in which the enzymes tagatose epimerase and fucose isomerase are co-incubated with a micro-organism able to convert L-galactose to L- ascorbic acid. The micro-organism ...  
WO/2006/134374A3
There is provided a method for producing L-ascorbic acid (vitamin C) in which the enzymes tagatose epimerase and fucose isomerase are co-incubated with a micro-organism able to convert L-galactose to L- ascorbic acid. The micro-organism ...  
WO/2006/133332A3
A process for the enzyme-catalyzed preparation of cyclic ester oligomers from dicarboxylic acids and/or dicarboxylic acid derivatives and diols, hydroxycarboxylic acids and/or hydroxycarboxylic acid esters, and/or linear ester oligomers ...  
WO2006084706A3
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the fu...  
WO/2006/133332A2
A process for the enzyme-catalyzed preparation of cyclic ester oligomers from dicarboxylic acids and/or dicarboxylic acid derivatives and diols, hydroxycarboxylic acids and/or hydroxycarboxylic acid esters, and/or linear ester oligomers ...  
WO/2006/131098A2
The invention relates to a method for producing rhizoxin and derivatives of rhizoxin. The aim of the invention is to produce novel micro-organisms that synthesise rhizoxin or derivatives of rhizoxin, and to provide a method for producing...  
WO2006084644A3
The present invention relates to newly identified microorganisms capable of direct production of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also relates to polynucleotide sequences comprising genes that en...  
WO/2006/131098A3
The invention relates to a method for producing rhizoxin and derivatives of rhizoxin. The aim of the invention is to produce novel micro-organisms that synthesise rhizoxin or derivatives of rhizoxin, and to provide a method for producing...  
WO/2006/130657A2
The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula (Ib).  
WO/2006/130657A3
The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula (Ib).  
WO/2006/126498A1
The invention relates to a novel amino group transferase, DNA encoding the enzyme, a recombinant vector into which the DNA has been introduced, and a transformant into which the vector has been introduced. Further, the invention also rel...  
WO/2006/126723A1
A genetically modified microorganism capable of directly producing a 16-hydroxylated macrolide compound; and a process for producing a 16-hydroxylated macrolide compound using the microorganism. Specifically, a genetically modified micro...  
WO/2006/123007A1
The invention relates to a genetically-modified micro-organism which can be used to produce 6HNA (6-hydroxynicotinic acid) from NA (nicotinic acid), based on the genetic modification of one or more genes of the nic route, which may be of...  
WO2006046152A3
The invention provides a method for the heterologous expression of a secondary metabolite encoded by a biosynthetic pathway. Also provided is a method for introducing a large sized DNA molecule into the chromosome of a heterologous host ...  
WO/2006/120813A1
An object of the invention is to provide a method capable of producing D-glucuronic acid and D-glucuronolactone easily and safely in high yield and at low cost. The invention provides a method for producing glucuronic acid and/or glucuro...  
WO2006094800A3
The invention relates to a process, which comprises converting a chemical substrate into a chemical product by a cascade reaction wherein an enzyme-catalysed chemical transformation reaction and a metal-catalysed chemical transformation ...  
WO2006084749A3
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C), e.g. the RCS 02 gene coding for an ?xidoreductase (EC 1.10) ....  
WO2006084643A3
The present invention relates to newly identified microorganisms capable of direct production of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also relates to polynucleotide sequences comprising genes that en...  
WO/2006/116487A3
Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing ...  
WO/2006/116487A2
Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing ...  
WO/2006/113147A3
Herein is disclosed a method of generating ascorbic acid from yeast transformed with a mannose epimerase. In a further embodiment, the yeast can be further transformed with a myoinositol phosphatase. In the method, the transformed yeast ...  
WO2005106011A3
A process for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV is provided which employs a BOC-protected amine of the structure (3) prepared by subjecting an acid of the structure (1) to reduce amin...  
WO/2006/113147A2
Herein is disclosed a method of generating ascorbic acid from yeast transformed with a mannose epimerase. In a further embodiment, the yeast can be further transformed with a myoinositol phosphatase. In the method, the transformed yeast ...  
WO/2006/109198A3
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific glycidyl ether hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, ve...  
WO/2006/109198A2
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific glycidyl ether hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, ve...  
WO/2006/105843A3
The invention relates to a method for splitting rutinosides in order to obtain rhamnose and/or the corresponding aglycones. Said method is characterised in that the reaction is carried out in the presence of yeast. The invention also rel...  
WO/2006/101073A1
[PROBLEMS] To search a substance capable of inhibiting the induction of the expression of GRP78 to find a novel anti-cancer agent. [MEANS FOR SOLVING PROBLEMS] A novel compound represented by the chemical formula 1 is now found as a subs...  

Matches 551 - 600 out of 8,317