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Matches 551 - 600 out of 8,524

Document Document Title
WO2007103389A9
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/118320A1
The present invention provides a scalable process for producing a concentrate containing a mass of a farnesylated dibenzodiazepinone by fermenting in an aqueous culture medium a strain of a microorganism that is capable of producing the ...  
WO/2007/113268A1
The present invention relates to 4,5-dihydromacbecin analogues according to the formula (IA) or (IB) below, or a pharmaceutically acceptable salt there of: wherein: R1 represents H or CONH2. that are useful, e.g. in the treatment of canc...  
WO/2007/113270A1
The present invention relates to 15-0-desmethylmacbecin analogues according to the formula (IA) or (IB) below, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 either both represent H or together they represent a bond (i...  
WO/2007/114125A1
Disclosed is a process for production of an N-(monohydroxy-2-adamantyl)-phthalimide derivative, which is a compound useful as an intermediate for the production of a functional resin or pharmaceutical, in a high yield and at a low cost. ...  
WO/2007/112299A3
Disclosed and claimed herein are novel biocatalysts for converting racemic mixtures of amino acids to an enantiomerically pure (S) form of the amino acid, methods for their use, and the enantiomerically enriched products of such biocatal...  
WO/2007/112299A2
Disclosed and claimed herein are novel biocatalysts for converting racemic mixtures of amino acids to an enantiomerically pure (S) form of the amino acid, methods for their use, and the enantiomerically enriched products of such biocatal...  
WO/2007/111203A1
Disclosed is a triprenyl phenol compound having a thrombolysis-enhancing activity. Also disclosed is a process for production of the triprenyl phenol compound. The triprenyl phenol compound is represented by the general formula (II) or (...  
WO/2007/108108A1
The invention is directed to a novel stemphone compound in which a microorganism which belongs to the genus Aspergillus and has an ability to produce a stemphone compound selected from the group consisting of stemphone D compound, stemph...  
WO/2007/105280A1
Disclosed is a process for producing a novel acylated epigallocatechin gallate derivative in which an acyl group is introduced selectively and efficiently to epigallocatechin gallate. A process for producing an acylated derivative of epi...  
WO/2007/102936A2
This invention provides genes and their encoded proteins, involved in the biosynthesis of farnesyl dibenzodiazepinones, including ECO-04601. The invention relates to expression vectors comprising the genes and to host cells transformed w...  
WO/2007/103389A3
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/102936A3
This invention provides genes and their encoded proteins, involved in the biosynthesis of farnesyl dibenzodiazepinones, including ECO-04601. The invention relates to expression vectors comprising the genes and to host cells transformed w...  
WO/2007/102396A1
Disclosed is a method for production of a labeled sphingolipid, comprising reacting a sphingolipid or lysosphingolipid with an aliphatic carboxylic acid having a label selected from the group consisting of a substance capable of forming ...  
WO/2007/103389A2
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/099107A1
A process for the production of an optically enriched oxazolidinone of the formula (2a) or (2b), by reacting an epoxide of the formula (1 ) with cyanate in the presence of halo- hydrin dehalogenase.  
WO/2007/097106A1
By using sclareol as a substrate, a dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]-furan intermediate is efficiently produced. As a result of intensive studies with the aim of isolating and identifying a microorganism having a character...  
WO/2007/095696A1
The present invention relates to polyketide xanthones of the kibdelone class and their use as antibacterial and anticancer agents is described. Methods of preparing kibdelone compounds, pharmaceutical compositions containing them, and th...  
WO2006113147B1
Herein is disclosed a method of generating ascorbic acid from yeast transformed with a mannose epimerase. In a further embodiment, the yeast can be further transformed with a myoinositol phosphatase. In the method, the transformed yeast ...  
WO/2007/082402A2
The process according to the invention for regioselective N(5)-formylation of (6S)-5,6,7,8-tetrahydropteroic acid and derivatives thereof which are defined in formula (I) is characterized in that an aqueous buffer solution having a pH of...  
WO/2007/084808A2
Methods for preparing substantially non-antigenic polymers having lone electron pair-containing moieties in high purity are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of...  
WO/2007/082402A3
The process according to the invention for regioselective N(5)-formylation of (6S)-5,6,7,8-tetrahydropteroic acid and derivatives thereof which are defined in formula (I) is characterized in that an aqueous buffer solution having a pH of...  
WO2007028239B1
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO/2007/082178A3
A method of inhibiting 15-keto prostaglandin-Δ13-reductase 2 by contacting 15-keto prostaglandin-Δ13-reductase 2 with an aryl compound of Formula (I), (II), (III), or (IV) shown herein. Also disclosed are methods of treating peroxisome...  
WO/2007/078263A2
Technical solution is related to industry production microorganism Streptomyces toxytricini CCM 7349 and method of lipstatin biotechnology preparation by this strain. Production strain listed above with use of two step vegetative inoculu...  
WO/2007/078263A3
Technical solution is related to industry production microorganism Streptomyces toxytricini CCM 7349 and method of lipstatin biotechnology preparation by this strain. Production strain listed above with use of two step vegetative inoculu...  
WO/2007/074060A1
The invention relates to a method for production of optically active (1S)-3-chloro-1-(2-thienyl)-propan-1-ol of formula (I), wherein 3-chloro-1 -(2-thienyl)-propan-1-one of formula (II) is reduced in a medium to give the compound of form...  
WO2007035693A9
Novel isonitrile biosynthetic enzymes isnA and isnB which together possess a catalytic activity of converting an amine-containing compound to an isonitrile-containing compound are described. The genes that encode such enzymes, recombinan...  
WO/2007/074070A1
The invention relates to a method for producing optically active alkanols of formula (I), in which n represents a whole number from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, c...  
WO/2007/071599A3
A process for the production of an optically enriched tertiary alcohol of the formula (2a) or (2b), by reacting an epoxide of the formula (1) with a nucleophilic agent Nu in the presence of halohydrin dehalogenase.  
WO/2007/068498A1
The invention relates to a process for the preparation of δ-lactones by reacting acetaldehyde and a substituted acetaldehyde in the presence of an aldolase, preferably a DERA from Escherichia coli, from Bacillus subtilis or from a Geoba...  
WO/2007/067698A2
The invention concerns a method having the steps of: combining an aqueous fermentation broth containing ansamitocins with a water-immiscible solvent and a water-soluble solvent to form an organic layer and an aqueous layer, wherein: (i) ...  
WO/2007/067698A3
The invention concerns a method having the steps of: combining an aqueous fermentation broth containing ansamitocins with a water-immiscible solvent and a water-soluble solvent to form an organic layer and an aqueous layer, wherein: (i) ...  
WO/2007/063866A1
An industrially advantageous process for producing a compound capable of inhibiting an HMG-CoA reductase and having an activity of decreasing the serum cholesterol level, which is characterized by using a protein comprising an amino acid...  
WO/2007/051651A1
Disclosed are strains of fungus Claviceps purpurea (Fr.) Tul., that produce a high content of total ergot peptide alkaloids and an amount of beta-ergokryptine greater than the amount of alpha-ergokryptine during parasitic growth on a cer...  
WO/2007/046943A2
The present invention relates to the production process of biotin by fermentation using genetically engineered microorganisms, including Escherichia coli and Pseudomonas mutabilis, and DNA sequences and vectors to be used in such process.  
WO2005104864A8
Edible oil comprising statin comprising at least 90% of di- and/or triglycerides having a saturated fatty acid (SAFA) content of less than 25 wt%, preferably containing at least 4 mg/g statin. Process for the preparation of an edible oil...  
WO2005104871A8
A composition comprising statin wherein the composition is a flour comprising less than 10 wt.% of fat and the use of the composition comprising statin in the preparation a food product is disclosed. The process for the preparation of th...  
WO/2007/040082A1
Disclosed is a composition for treatment of nephritis which contains a triprenyl phenol compound as an active ingredient. The composition preferably contains a triprenyl phenol compound represented by the general formula (I) below as an ...  
WO/2007/039816A3
The present invention relates to improved fermentation processes for the preparation of tacrolimus or a salt or derivative thereof by culturing a microorganism capable of producing tacrolimus or a salt or derivative thereof under submerg...  
WO/2007/039816A2
The present invention relates to improved fermentation processes for the preparation of tacrolimus or a salt or derivative thereof by culturing a microorganism capable of producing tacrolimus or a salt or derivative thereof under submerg...  
WO/2007/035693A3
Novel isonitrile biosynthetic enzymes isnA and isnB which together possess a catalytic activity of converting an amine-containing compound to an isonitrile-containing compound are described. The genes that encode such enzymes, recombinan...  
WO/2007/030772A3
Genetically engineered Streptomyces clavuligerus strains with improved capabilities to produce clavulanic acid are provided. The strains are genetically engineered by disrupting newly identified glyceraldehyde-3-phosphate dehydrogenase (...  
WO/2007/028602A1
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the fu...  
WO/2007/028609A1
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the fu...  
WO/2007/030662A1
Disclosed are methods of modulating biosynthesis of Salinosporamide A and its analogs, which are useful in treating cancer, inflammatory conditions, and/or infectious disease. The methods involve, for example, genetic manipulation, selec...  
WO/2007/028239A2
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO/2007/028239A3
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO2006136521A8
A process is described for the preparation of escitalopram and the pharmaceutically acceptable salts thereof starting from 5-cyanophthalide by a process which provides an enantioselective enzymatic deacylation reaction of a complex of th...  
WO2006134623B1
The present invention describes a method for increasing the survival of the bacteria of Rhizobium genus, comprising the steps of: making the bacteria to grow in a chemically defined medium; keeping the bacteria in growth stationary phase...  

Matches 551 - 600 out of 8,524