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Matches 551 - 600 out of 8,574

Document Document Title
WO/2008/006037A3
A glycerol utilizing cell and a method for the production of glycerol-derived target compounds are provided. The glycerol utilizing cell may comprise a glycerol metabolizing system or a glycerol uptake protein and be used to produce a gl...  
WO/2008/000416A1
The present invention relates to microorganisms genetically engineered to reduce carbon source diversion throughout the bioconversion of a carbon source, such as e.g. sorbitol, into biomass. Processes for generating such microorganisms a...  
WO/2008/002600A2
The present invention relates to a sahnosporamide A composition and methods of making salinosporamide A and analogs thereof. The present invention also relates to methods of identifying 2OS proteasome inhibiting agents.  
WO2007082402B1
The process according to the invention for regioselective N(5)-formylation of (6S)-5,6,7,8-tetrahydropteroic acid and derivatives thereof which are defined in formula (I) is characterized in that an aqueous buffer solution having a pH of...  
WO/2008/000415A1
The present invention relates to microorganisms genetically engineered to reduce carbon source diversion throughout the bioconversion of a carbon source, such as e.g. sorbitol, into biomass. Processes for generating such microorganisms a...  
WO/2008/002665A1
The present invention provides a method of preparing acid metabolites, such as mycophenolic acid, and a strain of Penicillium sp. with accession number CCM 8364 for use in such method, which method produces mycophenolic acid at increased...  
WO/2008/001306A3
The present invention relates to an isolated microorganism of the strain type SPRT (=DSM 44925T = NRRL B-24448T). The microorganism preferably includes genetic material of GenBank accession number DQ141528 (16S-rDNA-sequence). The invent...  
WO/2007/147801A1
The present invention provides a fermentative process for the synthesis of simvastatin by providing a host capable of incorporating the 2,2-dimethylbutyrate side chain into simvastatin, i.e. by customizing a polyketide synthase gene opti...  
WO/2007/148514A1
Disclosed is a method for synthesis of a 4-hydroxy-2-quinoline by using an enzyme under clean and mild conditions in a simple manner. More specifically, disclosed is a method for synthesis of a 4-hydroxy-2-quinoline by conducting unimole...  
WO/2007/148412A1
An FKI-3389 substance is produced by culturing a microorganism (NITE ABP-244), which is a filamentous bacterium and has an ability to produce the FKI-3389 substance, in a medium, accumulating the FKI-3389 substance in the culture and iso...  
WO/2007/144368A3
The invention relates to the preparation of phenolics derivatives by enzymatic condensation of phenolics selected among pyrocatechol or its derivatives with the glucose moiety of sucrose. The production of said phenolics derivatives is a...  
WO/2007/144368A2
The invention relates to the preparation of phenolics derivatives by enzymatic condensation of phenolics selected among pyrocatechol or its derivatives with the glucose moiety of sucrose. The production of said phenolics derivatives is a...  
WO/2007/141945A1
[PROBLEMS] To provide a simple process for production of epitheaflagallin and epitheaflagallin-3-O-gallate which can be used in a food directly, and a process for production of a beverage containing epitheaflagallin and epitheaflagallin-...  
WO/2007/142222A1
Disclosed is an effective method for producing pyridoxamine by employing a fermentation technique. Pyridoxamine is one of the substances having a vitamin B6 activity and is useful as a pharmaceutical agent or an intermediate for the synt...  
WO/2007/139871A2
The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin.  
WO/2007/137510A1
A bacillus pumilus strain for high yield of tetramethylpyrazine, named as Bacillus pumilus RX3-17, deposited with China Center for Type Culture Collection under the deposit number CCTCC M 206043 on 19 Apr. 2006. The strain, isolated from...  
WO/2007/137816A1
The invention relates to a process for the preparation of intermediates, which can suitably be used in the preparation of active pharmaceutical ingredients, in particular in the preparation of HMG-CoA reductase inhibitors, more in partic...  
WO/2007/134836A1
The present invention pertains to the production of secondary metabolites and particularly to the production of lipstatin. Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention ...  
WO/2007/136614A3
The present invention provides a novel and sensitive means of monitoring Alzheimer's disease. The method consists of the construction of statistically relevant multi-analyte panels, through the use of shrunken centroids (SC), simulated a...  
WO/2007/132937A1
Seven kinds of novel antibiotics could be produced by culturing a strain named Microbispora sp. A34030 strain (deposited under the accession number of FERM BP-10505 under Budapest Treaty) which had been isolated from a soil sample. The s...  
WO/2007/128469A1
The invention relates to a process for the preparation of an enantiomerically enriched nitrile by reacting an epihalohydrin (derivative) with Br- and CN- in the presence of an enantioselective haloalcohol dehalogenase. The process of the...  
WO2007103389A9
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/118320A1
The present invention provides a scalable process for producing a concentrate containing a mass of a farnesylated dibenzodiazepinone by fermenting in an aqueous culture medium a strain of a microorganism that is capable of producing the ...  
WO/2007/113268A1
The present invention relates to 4,5-dihydromacbecin analogues according to the formula (IA) or (IB) below, or a pharmaceutically acceptable salt there of: wherein: R1 represents H or CONH2. that are useful, e.g. in the treatment of canc...  
WO/2007/113270A1
The present invention relates to 15-0-desmethylmacbecin analogues according to the formula (IA) or (IB) below, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 either both represent H or together they represent a bond (i...  
WO/2007/114125A1
Disclosed is a process for production of an N-(monohydroxy-2-adamantyl)-phthalimide derivative, which is a compound useful as an intermediate for the production of a functional resin or pharmaceutical, in a high yield and at a low cost. ...  
WO/2007/112299A3
Disclosed and claimed herein are novel biocatalysts for converting racemic mixtures of amino acids to an enantiomerically pure (S) form of the amino acid, methods for their use, and the enantiomerically enriched products of such biocatal...  
WO/2007/112299A2
Disclosed and claimed herein are novel biocatalysts for converting racemic mixtures of amino acids to an enantiomerically pure (S) form of the amino acid, methods for their use, and the enantiomerically enriched products of such biocatal...  
WO/2007/111203A1
Disclosed is a triprenyl phenol compound having a thrombolysis-enhancing activity. Also disclosed is a process for production of the triprenyl phenol compound. The triprenyl phenol compound is represented by the general formula (II) or (...  
WO/2007/108108A1
The invention is directed to a novel stemphone compound in which a microorganism which belongs to the genus Aspergillus and has an ability to produce a stemphone compound selected from the group consisting of stemphone D compound, stemph...  
WO/2007/105280A1
Disclosed is a process for producing a novel acylated epigallocatechin gallate derivative in which an acyl group is introduced selectively and efficiently to epigallocatechin gallate. A process for producing an acylated derivative of epi...  
WO/2007/102936A2
This invention provides genes and their encoded proteins, involved in the biosynthesis of farnesyl dibenzodiazepinones, including ECO-04601. The invention relates to expression vectors comprising the genes and to host cells transformed w...  
WO/2007/103389A3
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/102936A3
This invention provides genes and their encoded proteins, involved in the biosynthesis of farnesyl dibenzodiazepinones, including ECO-04601. The invention relates to expression vectors comprising the genes and to host cells transformed w...  
WO/2007/102396A1
Disclosed is a method for production of a labeled sphingolipid, comprising reacting a sphingolipid or lysosphingolipid with an aliphatic carboxylic acid having a label selected from the group consisting of a substance capable of forming ...  
WO/2007/103389A2
This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using thes...  
WO/2007/099107A1
A process for the production of an optically enriched oxazolidinone of the formula (2a) or (2b), by reacting an epoxide of the formula (1 ) with cyanate in the presence of halo- hydrin dehalogenase.  
WO/2007/097106A1
By using sclareol as a substrate, a dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]-furan intermediate is efficiently produced. As a result of intensive studies with the aim of isolating and identifying a microorganism having a character...  
WO/2007/095696A1
The present invention relates to polyketide xanthones of the kibdelone class and their use as antibacterial and anticancer agents is described. Methods of preparing kibdelone compounds, pharmaceutical compositions containing them, and th...  
WO2006113147B1
Herein is disclosed a method of generating ascorbic acid from yeast transformed with a mannose epimerase. In a further embodiment, the yeast can be further transformed with a myoinositol phosphatase. In the method, the transformed yeast ...  
WO/2007/082402A2
The process according to the invention for regioselective N(5)-formylation of (6S)-5,6,7,8-tetrahydropteroic acid and derivatives thereof which are defined in formula (I) is characterized in that an aqueous buffer solution having a pH of...  
WO/2007/084808A2
Methods for preparing substantially non-antigenic polymers having lone electron pair-containing moieties in high purity are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of...  
WO/2007/082402A3
The process according to the invention for regioselective N(5)-formylation of (6S)-5,6,7,8-tetrahydropteroic acid and derivatives thereof which are defined in formula (I) is characterized in that an aqueous buffer solution having a pH of...  
WO2007028239B1
The isolation and identification of two O-methyltransferases from the hops plant (Humulus lupulus L.), designated as OMT1 (SEQ ID NO. 1) and OMT2 (SEQ ID NO. 3) is described.  
WO/2007/082178A3
A method of inhibiting 15-keto prostaglandin-Δ13-reductase 2 by contacting 15-keto prostaglandin-Δ13-reductase 2 with an aryl compound of Formula (I), (II), (III), or (IV) shown herein. Also disclosed are methods of treating peroxisome...  
WO/2007/078263A2
Technical solution is related to industry production microorganism Streptomyces toxytricini CCM 7349 and method of lipstatin biotechnology preparation by this strain. Production strain listed above with use of two step vegetative inoculu...  
WO/2007/078263A3
Technical solution is related to industry production microorganism Streptomyces toxytricini CCM 7349 and method of lipstatin biotechnology preparation by this strain. Production strain listed above with use of two step vegetative inoculu...  
WO/2007/074060A1
The invention relates to a method for production of optically active (1S)-3-chloro-1-(2-thienyl)-propan-1-ol of formula (I), wherein 3-chloro-1 -(2-thienyl)-propan-1-one of formula (II) is reduced in a medium to give the compound of form...  
WO2007035693A9
Novel isonitrile biosynthetic enzymes isnA and isnB which together possess a catalytic activity of converting an amine-containing compound to an isonitrile-containing compound are described. The genes that encode such enzymes, recombinan...  
WO/2007/074070A1
The invention relates to a method for producing optically active alkanols of formula (I), in which n represents a whole number from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, c...  

Matches 551 - 600 out of 8,574