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Matches 651 - 700 out of 7,973

Document Document Title
WO2005054266A3
14-membered macrolide compounds such as erythromycins are provided with functional groups at the 14- and/or 15-position by providing a 14-membered aglycone template and feeding it to a strain capable of hydroxylating it at the 14 and/or ...  
WO/2005/106011A2
A process for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV is provided which employs a BOC-protected amine of the structure (3) prepared by subjecting an acid of the structure (1) to reduce amin...  
WO/2005/105812A1
Methods for the synthesis of regiospecific rapamycin 42-hemiesters and regiospecific FK506 32-esters with dicarboxylic acids is described. The methods involve catalyzing the reaction between a rapamycin or a FK-506 and a dicarboxylic anh...  
WO/2005/106007A1
A method for rapamycin-specific labeling using rapI, rapM and/or rapQ enzymes is described. Also are methods for generating crude enzyme extracts useful in the method of the invention. Uses of the specifically labeled rapamycin as diagno...  
WO/2005/105811A1
A method for the regiospecific synthesis of rapamycin 42-ester derivatives is described. The method involves lipase-catalyzed acylation of 42 hydroxy rapamycin with an acyl donor such as a vinyl ester, an isopropenyl ester or an anhydrid...  
WO/2005/106006A3
Disclosed herein is a process for producing 6-hydroxynicotinic acid via biotransformation, the process comprises hydroxylation of nicotinic acid in aqueous medium using a novel microbial strain, Yersinia pseudotuberculosis MTCC 5129 cell...  
WO/2005/104864A1
Edible oil comprising statin comprising at least 90% of di- and/or triglycerides having a saturated fatty acid (SAFA) content of less than 25 wt%, preferably containing at least 4 mg/g statin. Process for the preparation of an edible oil...  
WO/2005/104871A1
A composition comprising statin wherein the composition is a flour comprising less than 10 wt.% of fat and the use of the composition comprising statin in the preparation a food product is disclosed. The process for the preparation of th...  
WO/2005/103280A1
A process for producing either a 3-benzamido-2-hydroxycarboxylic acid represented by 3-benzamido-2-hydroxy-3-phenylpropionic acid or a salt thereof. The process is safe and suitable for industrial production, and the target compound havi...  
WO2005017159A3
The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleo...  
WO2005021586A3
The invention provides a nucleic acid molecule comprising at least a functional fragment of the viomycin biosynthetic gene cluster, functional proteins encoded by the cluster, expression cassettes and recombinant host cells comprising a ...  
WO/2005/100582A3
The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a...  
WO2005073387A3
The invention relates to a method for obtaining the molybdopterin derivative precursor Z, whereby an over-production of precursor Z occurs in host organisms by recombinant expression of precursor Z synthesizing proteins. The invention fu...  
WO/2005/100578A2
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vect...  
WO/2005/100587A2
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific 2,2-disubstituted epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polyp...  
WO/2005/100581A1
Novel isochroman compound pseudodeflectusin that is isolated from marine microbes parasitizing seaweeds and purified, having a chemical structure represented by the following formula (1) and that exhibits high growth inhibiting activity ...  
WO/2005/100569A2
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, v...  
WO/2005/100582A2
The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a...  
WO/2005/098011A1
The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.  
WO/2005/098013A1
The invention relates to a process for the preparation of an aliphatic carbonate. This polycarbonate results from an enzymatic polymerization reaction between a dialkyl carbonate and a diol. During substantially the whole process of the ...  
WO/2005/098012A1
An industrial process for producing hydroxyaldehydes efficiently, which solves the problems of conventional DERA, e.g., low stability to aldehydes, low catalytic activity for aldol condensation, and uncontrollableness in the number of co...  
WO2005009391A3
Fermentation of a nutrient medium with a eubacterium Streptomyces sp. yields a novel antibacterial compound of structure (I).  
WO/2005/092916A1
As the results of studies for searching for a substance capable of selectively inducing cell death into a tumor cell with the use of cells having an oncogene transferred thereinto, it is found out that novel peptide-type fermentation pro...  
WO2004035760A3
Three gene clusters that together encode albicidin biosynthesis, the complete gene DNA sequences, and the deduced protein sequences for the enzymes and methods for using the DNA sequences are disclosed and discussed as well as methods fo...  
WO/2005/090384A1
A microorganism belonging to the genus Streptomyces and being capable of producing substance K01-0509-A1 and/or substance K01-0509-A2 is cultured in a medium. Then, the substance K01-0509-A1 and/or the substance K01-0509-A2 having been t...  
WO/2005/090326A1
A microorganism belonging to filamentous fungi, capable of producing antibiotic FKI-1778A and/or FKI-1778B and/or FKI-1778C and/or FKI-1778D is cultured in a culture medium to thereby accumulate the antibiotic FKI-1778A and/or FKI-1778B ...  
WO/2005/086907A2
Domains of ambruticin polyketide synthase and modificationenzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin ana...  
WO/2005/084305A2
The invention provides methods and materials related to producing flavonoids as well as other organic compounds. For example, the invention provides isolated nucleic acids, polypeptides, host cells, and methods and materials for producin...  
WO/2005/085257A1
This invention relates, in part, to macrolide compounds, actinomycete strains for producing them, and pharmaceutical compositions containing them.  
WO/2005/085435A1
A process for producing picolinic acid compounds. The process, which is for producing picolinic acid compounds, comprises reacting phenyl-containing aromatic compounds represented by the following formula (I), (II), or (III) with an arom...  
WO/2005/084305A3
The invention provides methods and materials related to producing flavonoids as well as other organic compounds. For example, the invention provides isolated nucleic acids, polypeptides, host cells, and methods and materials for producin...  
WO2005072711A3
The invention relates to an improved method for cultivating the fungus Penicillium chrysogenum, especially strain KIP 3201, for producing the antitumoral natural substance Sorbicillactone A of formula (I) and its derivatives in an optimi...  
WO/2005/085459A1
Methods of forming organic molecules comprising contacting a hydrolase enzyme with an organic reactant are provided. Methods for forming an organosilicon molecule comprising contacting cutinase with an organosilicon reactant are also pro...  
WO/2005/083102A1
It is intended to provide a novel process for producing an optically active 1,4-benzodioxin-2-carboxylic acid derivative, which is usable as an intermediate in synthesizing an optically active drug, via biological conversion. Namely, a 6...  
WO/2005/079355A3
The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp.ina nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stre...  
WO2004106557A3
The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganis...  
WO/2005/079355A2
The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp.ina nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stre...  
WO/2005/080549A2
The invention relates to the use of trioxacarcins as agents for treating infections caused by fungi, parasites, viruses or bacteria. The invention also relates to the novel trioxacarcin derivatives as such, to drugs containing them or th...  
WO/2005/078110A1
Disclosed is a method for producing flavor-active terpenes from terpene hydrocarbons. According to said method, a lyophilized mycel which is first rehydrated and is then mixed with the substrate is used preferably in a submerged culture ...  
WO/2005/075659A1
The present invention relates to a method for increasing the amount of a clavam produced by a microorganism. In particular, the invention relates to a method for increasing the amount of produced clavulanic acid.  
WO/2005/075157A1
The invention comprises a method of an industrial robot (), comprising a control unit () and a manipulator () including a tool () comprising a defined TCP and a device for determining a distance error (d*) between an inaccurately program...  
WO/2005/074481A2
Methods for processing spectra are disclosed. The method includes obtaining a plurality of spectra (26), each spectrum in the plurality of spectra comprising a signal including a signal strength as a function of time-of-flight, mass-to-c...  
WO/2005/075658A1
The present invention provides a process for the production of vitamin C from a substrate, such as for instance L-sorbosone using a microorganism belonging to the genus Ketogulonicigenium.  
WO/2005/073223A1
A method of stabilizing a macrolide compound and a process for efficiently producing the compound. The method, which is for stabilizing a 12-membered cyclic macrolide compound, e.g., that represented by the formula (I), comprises causing...  
WO/2005/073387A2
The invention relates to a method for obtaining the molybdopterin derivative precursor Z, whereby an over-production of precursor Z occurs in host organisms by recombinant expression of precursor Z synthesizing proteins. The invention fu...  
WO/2005/073389A1
The invention relates to a method for producing β-hydroxy nitro compounds of formula (I), in which R1 and R2, independent of one another, represent a C1-C20 alkyl radical, C6-C14 aryl radical, C1-C14-heteroaryl radical, optionally subst...  
WO/2005/073388A1
A process for producing an optically active 1,4-pentanediol which comprises asymmetrically reducing 5-hydroxy-2-pentanone, which is easily available at low cost. Also provided is a process for producing an optically active 1-substituted ...  
WO/2005/072711A2
The invention relates to an improved method for cultivating the fungus Penicillium chrysogenum, especially strain KIP 3201, for producing the antitumoral natural substance Sorbicillactone A of formula (I) and its derivatives in an optimi...  
WO/2005/069849A3
The present invention provides an improved process for producing a fermentation product in a fermentation medium, including ethanol, which process include a fermentation step, comprising subjecting the fermentation medium to at least one...  
WO/2005/069849A2
The present invention provides an improved process for producing a fermentation product in a fermentation medium, including ethanol, which process include a fermentation step, comprising subjecting the fermentation medium to at least one...  

Matches 651 - 700 out of 7,973