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Matches 651 - 700 out of 7,918

Document Document Title
WO/2005/085257A1
This invention relates, in part, to macrolide compounds, actinomycete strains for producing them, and pharmaceutical compositions containing them.  
WO/2005/085435A1
A process for producing picolinic acid compounds. The process, which is for producing picolinic acid compounds, comprises reacting phenyl-containing aromatic compounds represented by the following formula (I), (II), or (III) with an arom...  
WO/2005/084305A3
The invention provides methods and materials related to producing flavonoids as well as other organic compounds. For example, the invention provides isolated nucleic acids, polypeptides, host cells, and methods and materials for producin...  
WO2005072711A3
The invention relates to an improved method for cultivating the fungus Penicillium chrysogenum, especially strain KIP 3201, for producing the antitumoral natural substance Sorbicillactone A of formula (I) and its derivatives in an optimi...  
WO/2005/085459A1
Methods of forming organic molecules comprising contacting a hydrolase enzyme with an organic reactant are provided. Methods for forming an organosilicon molecule comprising contacting cutinase with an organosilicon reactant are also pro...  
WO/2005/083102A1
It is intended to provide a novel process for producing an optically active 1,4-benzodioxin-2-carboxylic acid derivative, which is usable as an intermediate in synthesizing an optically active drug, via biological conversion. Namely, a 6...  
WO/2005/079355A3
The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp.ina nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stre...  
WO2004106557A3
The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganis...  
WO/2005/079355A2
The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp.ina nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stre...  
WO/2005/080549A2
The invention relates to the use of trioxacarcins as agents for treating infections caused by fungi, parasites, viruses or bacteria. The invention also relates to the novel trioxacarcin derivatives as such, to drugs containing them or th...  
WO/2005/078110A1
Disclosed is a method for producing flavor-active terpenes from terpene hydrocarbons. According to said method, a lyophilized mycel which is first rehydrated and is then mixed with the substrate is used preferably in a submerged culture ...  
WO/2005/075659A1
The present invention relates to a method for increasing the amount of a clavam produced by a microorganism. In particular, the invention relates to a method for increasing the amount of produced clavulanic acid.  
WO/2005/075157A1
The invention comprises a method of an industrial robot (), comprising a control unit () and a manipulator () including a tool () comprising a defined TCP and a device for determining a distance error (d*) between an inaccurately program...  
WO/2005/074481A2
Methods for processing spectra are disclosed. The method includes obtaining a plurality of spectra (26), each spectrum in the plurality of spectra comprising a signal including a signal strength as a function of time-of-flight, mass-to-c...  
WO/2005/075658A1
The present invention provides a process for the production of vitamin C from a substrate, such as for instance L-sorbosone using a microorganism belonging to the genus Ketogulonicigenium.  
WO/2005/073223A1
A method of stabilizing a macrolide compound and a process for efficiently producing the compound. The method, which is for stabilizing a 12-membered cyclic macrolide compound, e.g., that represented by the formula (I), comprises causing...  
WO/2005/073387A2
The invention relates to a method for obtaining the molybdopterin derivative precursor Z, whereby an over-production of precursor Z occurs in host organisms by recombinant expression of precursor Z synthesizing proteins. The invention fu...  
WO/2005/073389A1
The invention relates to a method for producing β-hydroxy nitro compounds of formula (I), in which R1 and R2, independent of one another, represent a C1-C20 alkyl radical, C6-C14 aryl radical, C1-C14-heteroaryl radical, optionally subst...  
WO/2005/073388A1
A process for producing an optically active 1,4-pentanediol which comprises asymmetrically reducing 5-hydroxy-2-pentanone, which is easily available at low cost. Also provided is a process for producing an optically active 1-substituted ...  
WO/2005/072711A2
The invention relates to an improved method for cultivating the fungus Penicillium chrysogenum, especially strain KIP 3201, for producing the antitumoral natural substance Sorbicillactone A of formula (I) and its derivatives in an optimi...  
WO/2005/069849A3
The present invention provides an improved process for producing a fermentation product in a fermentation medium, including ethanol, which process include a fermentation step, comprising subjecting the fermentation medium to at least one...  
WO/2005/069849A2
The present invention provides an improved process for producing a fermentation product in a fermentation medium, including ethanol, which process include a fermentation step, comprising subjecting the fermentation medium to at least one...  
WO2004104205A3
The present invention relates to a process for preparing a chiral indole ester by enzymatic resolution using a lipase from Pseudomonas fluorescens as the catalyst for the enantioselective hydrolysis of an ester.  
WO2004007750A3
The invention provides polypeptides having a monooxygenase activity, polynucleotides encoding these enzymes, the use of such polynucleotides and polypeptides. In one aspect, the invention provides polypeptides having a monooxygenase acti...  
WO/2005/066353A1
The invention relates to a device for enzymatically producing baccatin III in an enzyme reactor (R). To this end, the enzyme reactor (R) comprises a hollow fiber ultrafiltration membrane (M), and an acetyl transferase from Taxus spec. is...  
WO/2005/063740A1
The present invention relates a novel compound, chrysogenazine containing both indole and diketopiperazine ring systems, isolated from the chloroform fraction of the fermentation broth of Penicillium chrysogenum and the gross structure o...  
WO2005052152A8
It is intended to provide a DNA participating in the hydroxylation of a macrolide compound 11107B and a novel method of producing a macrolide compound 11107D. More specifically speaking, a DNA participating in the biological conversion o...  
WO/2005/063963A1
The present invention relates to a tacrolimus producing strain, more precisely, a Streptomyces clavuligerus strain mass-producing tacrolimus represented by formula 1 and a method for mass-production of tacrolimus by using the same. The s...  
WO2004100649B1
Plant material enriched in secondary metabolites is produced in tissue culture under conditions that organogenically produce a proliferation of shoots and leafy material, and harvesting the leafy material and shoots while in a green, act...  
WO/2005/064006A1
The present invention relates to optically active heteroaromatic β -hydroxy esters of formula (I) useful in the synthesis of epothilone derivatives, to beta-keto esters of formula (IV) used to produce these intermediates by means of an ...  
WO2002097062A3
Recombinant DNA compounds that encode all or a portion of the narbonolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of narbonolide, narbonolide derivatives, and polyket...  
WO/2005/064002A1
The present invention relates to a method for mass production of secondary metabolites in plant cell culture, more specifically, to a method for production of secondary metabolites comprising the step of culturing plant cells in a medium...  
WO/2005/061461A1
Inhibitors against members of the heat shock protein 90 (hsp90) family, containing as the active ingredient benzenoid ansamycin derivatives represented by the general formula (I) which are useful as antitumor drug or other drugs or pharm...  
WO/2005/059152A1
A method of oxidising carbohydrates and/or carbohydrate derivatives having primary alcohol groups comprising contacting a reaction medium containing said carbohydrates and/or carbohydrate derivatives with a nitroxy radical mediator and a...  
WO/2005/054491A1
A process for producing (R)-tetrahydrothiophen-3-ol, comprising the step (A) of incubating tetrahydrothiophen-3-one in the presence of a preparation of strain belonging to the genus Penicillium, the genus Aspergillus or the genus Strepto...  
WO2005038009A3
The invention relates to a new microorganism Streptomyces glaucescens MTCC 5115 and a process for producing the immunosuppressant agent, tacrolimus (FK-506) utilizing the new microorganism Streptomyces glaucescens MTCC 5115. The inventio...  
WO/2005/053678A1
Therapeutic or preventive agents for ischemic neuropathy containing as the active ingredient compounds represented by the general formula [2]: wherein R1 and R4 are each independently hydrogen, carboxy, or alkoxycarbonyl; and R2 and R5 a...  
WO/2005/054266A2
14-membered macrolide compounds such as erythromycins are provided with functional groups at the 14- and/or 15-position by providing a 14-membered aglycone template and feeding it to a strain capable of hydroxylating it at the 14 and/or ...  
WO/2005/054186A2
The present invention relates to methods of preparing a stereoisomerically enriched compound of formula (I), wherein R6 is hydrogen, comprising treating a compound of formula (I), wherein R6 is chosen from C1-C10 alkyl, C2-C10 alkenyl, C...  
WO/2005/054186A3
The present invention relates to methods of preparing a stereoisomerically enriched compound of formula (I), wherein R6 is hydrogen, comprising treating a compound of formula (I), wherein R6 is chosen from C1-C10 alkyl, C2-C10 alkenyl, C...  
WO/2005/054250A1
The invention relates to tricyclacetalactonin, preparation and use there of. Said tricyclacetalactonin is prepared from Streptomyces albogriseolus of A2-2002. As being proved by the experiments, said compounds can be used as cell cycle i...  
WO/2005/052152A1
It is intended to provide a DNA participating in the hydroxylation of a macrolide compound 11107B and a novel method of producing a macrolide compound 11107D. More specifically speaking, a DNA participating in the biological conversion o...  
WO2004062558A3
The present invention describes a process for the preparation of beta-lactam antibiotics, cephalexin and ampicillin, wherein the beta-lactam nucleus is acylated with an acylating agent, D-phenylglycine, by means of a reaction biocatalyze...  
WO2005014839A3
The present invention relates to novel sweetener compositions comprising monatin and methods for making such compositions. The present invention also relates to sweetener compositions comprising specific monatin stereoisomers, specific b...  
WO/2005/047275A1
The invention relates to 2-phenyl-benzofuran compounds of formula (I), which are formed by the microorganism Aspergillus flavipes ST003878 (DSM 15290) during fermentation, to a method for the production thereof and to their use as medica...  
WO/2005/047509A2
The present invention relates to Mycobacterium ulceran virulence plasmid, pMUM001 and particularly to a cluster of genes carried by this plasmid that encode polyketide synthases (PKSs) and polyketide-modifying enzymes necessary and suffi...  
WO/2005/044803A1
The invention relates to bengamide derivatives which are formed by the micro-organism Myxococcus virescens ST200611 (DSM 15898), during fermentation, to the use thereof for the treatment of cancer, to medicaments containing bengamide der...  
WO/2005/045051A1
The present invention relates to a method for de-glycosylation of baicalin to produce baicalein by treating the baicalin with an enzyme having beta-glucuronidase activity under conditions such that baicalin is converted to baicalein.  
WO2004100649A3
Plant material enriched in secondary metabolites is produced in tissue culture under conditions that organogenically produce a proliferation of shoots and leafy material, and harvesting the leafy material and shoots while in a green, act...  
WO2004064745A3
Processes for preparing racemic and optically pure 3,6-dihydro-2H-pyrans of formulae H, I, N and O are described. These compounds may be further transformed into compounds of formulae J, K, L, M, P, Q, S, T, U, V, Y and Z with potential ...  

Matches 651 - 700 out of 7,918