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WO/2006/018211A1 |
The present invention relates to a process for the production of isoprenoids, in particular Coenzyme Q-10 by microorganisms. More particularly, the present invention relates to a process for increased production of Coenzyme Q-10 by micro...
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WO/2006/019209A1 |
The invention relates to a method and apparatus for compensating the lens shading phenomenon in image sensor. The invention first stores an inputted compensation reference value, identifies a center pixel using digital image signals rece...
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WO/2006/015811A2 |
The invention relates to a dihydrocoumarin that has been technically produced by the biotransformation of coumarin and to associated production variants that are carried out with the aid of isolated enzymes and/or microorganisms. Pure co...
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WO/2006/015727A2 |
The invention relates to a method for producing, in essence, enantiomer-pure 3-hydroxycarboxylic acids or esters of general formula (III) by reacting racemic oxetan-2-ones of general formula (I) with compounds R3-OH of general formula (I...
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WO/2006/010246A1 |
A gene encoding a littorine mutase/hydroxylase has been isolated and characterized. The gene is used in processes of altering alkaloid biosynthesis. Transgenic plants containing the gene have been produced and used for the production of ...
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WO/2006/012277A2 |
biocatalytic process for preparing enantiomerically enriched pramipexole and pramipexole precursors are disclosed.
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WO/2006/011156A1 |
A novel fermentation fed batch process for producing the immunosuppressant, Tacrolimus (FK-506), using the mutant microorganism Streptomyces sp. utilizing vegetative oil as sole source of carbon in production medium, is provided herewith.
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WO/2006/009518A1 |
There is provided a new strain, i.e. the alternaria alternata var. monosporus STÂ026R CGMCC No.0899, and its use in the production of paclitaxel. The invention also provides a method for the production of paclitaxel by using the strain ...
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WO/2006/009276A1 |
A polypeptide participating in the biosynthesis of pladienolide as a macrolide compound; a DNA coding for such a polypeptide; a variant thereof; a transformant in which part or the whole of such a DNA or variant thereof has been incorpor...
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WO/2006/010117A2 |
Methods and compositions are provided for production of flavonoids in microbial hosts. The compositions comprises a set of genes which encode for enzymes involved in one or more steps in the biosynthetic pathway for the conversion of phe...
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WO/2005/123933A1 |
A process for preparing the compound of formula (II) by reacting the compound of formula (I) with an enzyme that can hydrolyze the ester bond: formula (I) and (II) where * indicates a chiral center, R1 and R2 each independently represent...
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WO/2005/121327A2 |
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described. Also provided are novel Streptomyces species and metho...
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WO/2005/118777A2 |
The invention relates to a novel strain Saccharothrix actinomycete SA 103 deposited at CNCM on 16th February 2004, number I-3160 or a mutant strain thereof; a method and a medium for selection of said strain; and a method for the product...
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WO/2005/116061A2 |
The invention relates to DNA sequences coding for polypeptides which, in turn, participate in the enzymatic biosynthesis of polyketide compounds, and to amino acid sequences of said polypeptides. The invention also relates to the use of ...
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WO/2005/116200A2 |
The present invention provides polypeptides involved in cryptophycin biosynthesis and the nucleic acid molecules that encode such polypeptides. The nucleic acid molecules and polypeptides of the invention or variants thereof can be used ...
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WO/2005/112951A1 |
It is intended to provide an antitumor agent, which has established a strengthened function selectivity of acting exclusively on caner cells, lessened side effects, mastery of drug tolerance and so on, and has an activity of inducing cel...
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WO/2005/111214A1 |
The present invention relates to an ethanol producing microbial strain, such as Saccharomyces cerevisiae strain, being able to grow and produce ethanol from lignocellulosic hydrolysates comprising growth inhibiting compounds of the group...
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WO/2005/108590A2 |
The invention relates to a method for producing the optically active alkanols of formula (I), wherein n is an integer of from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, carbocy...
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WO/2005/108594A1 |
An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to catalyze the ammonolysis process.
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WO/2005/104871A1 |
A composition comprising statin wherein the composition is a flour comprising less than 10 wt.% of fat and the use of the composition comprising statin in the preparation a food product is disclosed. The process for the preparation of th...
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WO/2005/106006A2 |
Disclosed herein is a process for producing 6-hydroxynicotinic acid via biotransformation, the process comprises hydroxylation of nicotinic acid in aqueous medium using a novel microbial strain, Yersinia pseudotuberculosis MTCC 5129 cell...
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WO/2005/105811A1 |
A method for the regiospecific synthesis of rapamycin 42-ester derivatives is described. The method involves lipase-catalyzed acylation of 42 hydroxy rapamycin with an acyl donor such as a vinyl ester, an isopropenyl ester or an anhydrid...
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WO/2005/106011A2 |
A process for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV is provided which employs a BOC-protected amine of the structure (3) prepared by subjecting an acid of the structure (1) to reduce amin...
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WO/2005/106007A1 |
A method for rapamycin-specific labeling using rapI, rapM and/or rapQ enzymes is described. Also are methods for generating crude enzyme extracts useful in the method of the invention. Uses of the specifically labeled rapamycin as diagno...
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WO/2005/105812A1 |
Methods for the synthesis of regiospecific rapamycin 42-hemiesters and regiospecific FK506 32-esters with dicarboxylic acids is described. The methods involve catalyzing the reaction between a rapamycin or a FK-506 and a dicarboxylic anh...
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WO/2005/104864A1 |
Edible oil comprising statin comprising at least 90% of di- and/or triglycerides having a saturated fatty acid (SAFA) content of less than 25 wt%, preferably containing at least 4 mg/g statin. Process for the preparation of an edible oil...
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WO/2005/103280A1 |
A process for producing either a 3-benzamido-2-hydroxycarboxylic acid represented by 3-benzamido-2-hydroxy-3-phenylpropionic acid or a salt thereof. The process is safe and suitable for industrial production, and the target compound havi...
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WO/2005/100587A2 |
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific 2,2-disubstituted epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polyp...
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WO/2005/100581A1 |
Novel isochroman compound pseudodeflectusin that is isolated from marine microbes parasitizing seaweeds and purified, having a chemical structure represented by the following formula (1) and that exhibits high growth inhibiting activity ...
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WO/2005/100582A2 |
The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a...
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WO/2005/100578A2 |
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vect...
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WO/2005/100569A2 |
The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, v...
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WO/2005/098011A1 |
The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.
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WO/2005/098012A1 |
An industrial process for producing hydroxyaldehydes efficiently, which solves the problems of conventional DERA, e.g., low stability to aldehydes, low catalytic activity for aldol condensation, and uncontrollableness in the number of co...
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WO/2005/098013A1 |
The invention relates to a process for the preparation of an aliphatic carbonate. This polycarbonate results from an enzymatic polymerization reaction between a dialkyl carbonate and a diol. During substantially the whole process of the ...
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WO/2005/092916A1 |
As the results of studies for searching for a substance capable of selectively inducing cell death into a tumor cell with the use of cells having an oncogene transferred thereinto, it is found out that novel peptide-type fermentation pro...
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WO/2005/090384A1 |
A microorganism belonging to the genus Streptomyces and being capable of producing substance K01-0509-A1 and/or substance K01-0509-A2 is cultured in a medium. Then, the substance K01-0509-A1 and/or the substance K01-0509-A2 having been t...
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WO/2005/090326A1 |
A microorganism belonging to filamentous fungi, capable of producing antibiotic FKI-1778A and/or FKI-1778B and/or FKI-1778C and/or FKI-1778D is cultured in a culture medium to thereby accumulate the antibiotic FKI-1778A and/or FKI-1778B ...
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WO/2005/086907A2 |
Domains of ambruticin polyketide synthase and modificationenzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin ana...
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WO/2005/085459A1 |
Methods of forming organic molecules comprising contacting a hydrolase enzyme with an organic reactant are provided. Methods for forming an organosilicon molecule comprising contacting cutinase with an organosilicon reactant are also pro...
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WO/2005/085435A1 |
A process for producing picolinic acid compounds. The process, which is for producing picolinic acid compounds, comprises reacting phenyl-containing aromatic compounds represented by the following formula (I), (II), or (III) with an arom...
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WO/2005/084305A2 |
The invention provides methods and materials related to producing flavonoids as well as other organic compounds. For example, the invention provides isolated nucleic acids, polypeptides, host cells, and methods and materials for producin...
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WO/2005/085257A1 |
This invention relates, in part, to macrolide compounds, actinomycete strains for producing them, and pharmaceutical compositions containing them.
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WO/2005/083102A1 |
It is intended to provide a novel process for producing an optically active 1,4-benzodioxin-2-carboxylic acid derivative, which is usable as an intermediate in synthesizing an optically active drug, via biological conversion. Namely, a 6...
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WO/2005/079355A2 |
The invention is directed to a method for the production of taxanes by culturing suspension cells of Taxus sp.ina nutrient medium that comprises an indanoyl amino acid. The indanoyl amino acid may be added in batch mode or in a feed stre...
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WO/2005/080549A2 |
The invention relates to the use of trioxacarcins as agents for treating infections caused by fungi, parasites, viruses or bacteria. The invention also relates to the novel trioxacarcin derivatives as such, to drugs containing them or th...
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WO/2005/078110A1 |
Disclosed is a method for producing flavor-active terpenes from terpene hydrocarbons. According to said method, a lyophilized mycel which is first rehydrated and is then mixed with the substrate is used preferably in a submerged culture ...
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WO/2005/074481A2 |
Methods for processing spectra are disclosed. The method includes obtaining a plurality of spectra (26), each spectrum in the plurality of spectra comprising a signal including a signal strength as a function of time-of-flight, mass-to-c...
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WO/2005/075659A1 |
The present invention relates to a method for increasing the amount of a clavam produced by a microorganism. In particular, the invention relates to a method for increasing the amount of produced clavulanic acid.
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WO/2005/075157A1 |
The invention comprises a method of an industrial robot (), comprising a control unit () and a manipulator () including a tool () comprising a defined TCP and a device for determining a distance error (d*) between an inaccurately program...
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