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Matches 151 - 200 out of 8,515

Document Document Title
WO/2014/163301A1
Provided is a method for purifying quinolinic acid, comprising the steps of: preparing a fermentation solution containing at least one of quinolinic acid and a salt thereof; removing microbial cells from the fermentation solution; prepar...  
WO/2014/155214A1
The invention pertains to processes to produce dry biomass of pyripyropene producer organisms, processes to obtain pyripyropenes from such dry biomass, as well as to processes to produce compounds of Formula (III) and/or Formula (IV) and...  
WO/2014/154785A1
The invention relates to a method for stabilising a biomass of microalgae containing oxidation-sensitive metabolites selected from the group consisting of carotenoids (lutein, etc.), monounsaturated and polyunsaturated fatty acids (palmi...  
WO/2014/147578A4
The invention relates to the production of rifamycin analogs against drug resistant bacteria. The invention also relates to antibacterial compounds against drug resistant mycobacteria. The invention also provides for pharmaceutical compo...  
WO/2014/147578A3
The invention relates to the production of rifamycin analogs against drug resistant bacteria. The invention also relates to antibacterial compounds against drug resistant mycobacteria. The invention also provides for pharmaceutical compo...  
WO/2014/140786A1
A fed-batch fermentation method for production of bacteriochlorophyll a (Bchla) from Rhodovulum sulfidophilum, is provided wherein the growth medium contains an inorganic nitrogen compound as the nitrogen source and during fermentation t...  
WO/2014/144135A3
Provided herein are compositions and methods for improved production of acetyl-CoA and acetyl-CoA derived compounds in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence...  
WO/2014/145550A2
A corner bead for wallboard applications comprising a polymeric core having a bonding surface for bonding to wallboard wherein the bonding surface has applied thereto a water activated adhesive which is bonded to the polymeric core by a ...  
WO/2014/131995A1
A method for the enzymatic synthesis of diosmetin derivatives of formula (III):  
WO/2014/132902A1
Provided are: a compound represented by structural formula (1); a production method therefor; a microorganism capable of producing said compound; and a compound-containing composition, an anticancer agent, and an anti-Helicobacter pylori...  
WO/2014/131247A1
Provided is a method for synthesizing levo-praziquantel, comprising subjecting a chemically synthesized raceme or a certain enantiomer to a dynamic kinetic resolution catalyzed with a nitrile hydratase to produce an optically pure chiral...  
WO/2014/130613A3
Compounds of Formula (I) are useful as modulators of glycosylation. Compounds of Formula (I) have the following structure: (I) and the definitions of the other variables are provided herein.  
WO/2014/122109A1
The invention relates to enzymatic methods for preparing indigo and derivatives thereof, using peroxygenase and hydrogen peroxide.  
WO/2014/112387A1
The purpose of the invention is to provide a novel antitrypanosomal drug. The invention pertains to actinoallolides (A, B, C, D, and/or E), which are novel compounds produced by the actinomycete MK 10-036; to a method for producing said ...  
WO/2014/094462A1
The present invention provides a biological preparation method of (S)-3-methylamino-1-(2-thienyl)-1-propyl alcohol, wherein 3-methylamino-1-(2-thienyl)-1-acetone is used as a substrate; under a condition that a biocatalyst ketoreductase,...  
WO/2014/086702A3
The present invention relates to a biocatalytic process for preparing furandimethanols from hydroxymethylfurfurals, catalysed by suitable alcohol dehydrogenase enzymes, and to the use of the dimethanols thus prepared for preparation of o...  
WO/2014/080666A1
A diterpene compound represented by formula (VII) is a novel diterpene compound having an excellent skin-whitening effect. The present invention provides: a skin-whitening agent comprising a novel diterpene compound; and a method for pro...  
WO/2014/056006A1
The invention relates to enzymes for transforming ergopeptines, in particular by means of hydrolytic cleavage. Said enzymes are α/ β hydrolases which are hydrolytically cleaved in the cyclol ring of the ergopeptines for the transformat...  
WO/2014/056007A3
The invention relates to an enzyme preparation for transforming ergopeptines, containing at least one α/ß hydrolase which is hydrolytically cleaved in the cyclol ring of the ergopeptines and at least one amidase transforming the degrad...  
WO/2014/056007A2
The invention relates to an enzyme preparation for transforming ergopeptines, containing at least one α/ß hydrolase which is hydrolytically cleaved in the cyclol ring of the ergopeptines and at least one amidase transforming the degrad...  
WO/2014/036395A1
The invention provides a series of bioactive small molecules that target expanded r(CGG) repeats, termed r(CGG)exp, that causes Fragile X-associated Tremor Ataxia Syndrome (FXTAS). The compound was identified by using information on the ...  
WO/2014/030106A3
The present invention relates to a process for producing an optically active (2S,3S)-3- hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4 (5H)-one (Cis-lactam). More particularly, this invention relates to a process for making...  
WO/2014/029498A1
The present invention provides dimers and sulfonyl dimers of the compound of formula (I) having antibacterial activities.  
WO/2014/030096A3
Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprisi...  
WO/2014/015256A2
Provided herein are enzymatic methods for oxidation of 5-hydroxymethylfurfural (HMF) and HMF derivatives.  
WO/2014/015256A3
Provided herein are enzymatic methods for oxidation of 5-hydroxymethylfurfural (HMF) and HMF derivatives.  
WO/2014/005408A1
Provided in the present invention are antibiotic Tetrathiazomycin A and the preparation method thereof and the use in the preparation of an antitumour drug. The structural formula of Tetrathiazomycin A is shown as formula (I). The presen...  
WO/2013/190341A1
The present invention relates to an enantioselective enzymatic process for the preparation of an optically active 3-hydroxypiperidinecarboxylic acid derivative.  
WO/2013/173784A1
The invention provides new processes for making and purifying salts of hydroxylated cyclopentapyrimidine compounds, which are useful as AKT inhibitors used in the treatment of diseases such as cancer, including the monohydrochloride salt...  
WO/2013/167088A3
The present invention provides a synthesis method for L-cyclic alkyl amino acid and a pharmaceutical composition having said acid. Said synthesis method comprises: step a.) preparing a cyclic alkyl keto acid or cyclic alkyl keto acid sal...  
WO/2013/169725A2
The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proli...  
WO/2013/169610A1
The present invention is directed to processes for preparing an intermediate for a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorder...  
WO/2013/162478A1
There is provided a method of degrading a heterocyclic aldehyde compound comprising the step of treating the heterocyclic aldehyde compound with Enterobacter sp. microorganisms. There is also provided a method of degrading a carboxylic a...  
WO/2013/155868A1
Provided in the present invention is a method for increasing the yield of total flavonoids in Ganoderma lucidum mycelium with an expansin, comprising the steps of: (1) inoculating strains of Ganoderma lucidum into the PD liquid fermentat...  
WO/2013/153554A1
The present invention provides a novel method for producing rapamycin by submerged fermentation which comprises cultivating Streptomyces hygroscopicus (CBS 773.72) and mutants thereof. The present invention provides a high yielding mutan...  
WO/2013/143184A1
Provided is a streptomyces (Streptomyces sp.) strain SCSIO 03032, preserved in China Center for Type Culture Collection on July 18, 2011 with the preservation number CCTCC NO: M 2011258. The streptomyces (Streptomyces sp.) strain SCSIO 0...  
WO/2013/139987A1
The present invention relates to processes and intermediates useful for the manufacture of spiroindolone compounds such as (1'R,3'S)-5,7'-dichloro-6'-fluoro-3'-methyl-2',3',4',9'-tetr ahydrospiro[indoline-3,1'-pyrido[3, 4-b]indol]-2-one ...  
WO/2013/132118A1
The present invention relates to an isolated polynucleotide comprising ectoine- and hydroxyectoine-producing genes, preferably with at least two copies of the gene that encodes the ectoine hydroxylase enzyme, expression of which is direc...  
WO/2013/129661A1
The present invention provides a chroman derivative represented by general formula (I), which enables the production of an SMTP compound that has a desired structure. In the formula, each of Y1 and Y2 independently represents a hydrogen ...  
WO/2013/127915A1
Recombinant microbial cells and methods for producing melatonin and related compounds using such cells are described. More specifically, the recombinant microbial cell may comprise exogenous genes encoding one or more of an L-tryptophan ...  
WO/2013/127356A1
Provided are a preparation method of (R) - praziquantel and an intermediate thereof. 1-alkylcarbamoyl-3,4-dihydroisoquinoline or 1-ester-3,4-dihydroisoquinoline are used as starting materials of the preparation method; the starting m...  
WO/2013/127914A1
Recombinant microbial cells and methods for producing 5-hydroxytryptophan (5HTP) using such cells are described. More specifically, the recombinant microbial cell comprises an exogenous gene encoding an L-tryptophan hydroxylase, and mean...  
WO/2013/103246A2
The present invention relates to: a recombinant microorganism producing quinolinic acid which expresses a fusion protein in which L-aspartate oxidase and quinolinate synthase are linked by a linker; and a method for producing quinolinic ...  
WO/2013/103246A3
The present invention relates to: a recombinant microorganism producing quinolinic acid which expresses a fusion protein in which L-aspartate oxidase and quinolinate synthase are linked by a linker; and a method for producing quinolinic ...  
WO/2013/097424A1
Provided are a marine streptomyces sp., a compound of pyranosesquiterpenes and a preparation method and the use thereof. Streptomyces sp. SCSIO 01689 was deposited in the China Center for Type Culture Collection (CCTCC) on July 18, 2011,...  
WO/2013/095175A1
The invention relates to biotechnological industry, specifically to obtaining the substance of medicinal preparation stepharine sulfate out of the cell culture of Stephania glabra plant, and a method of quantitative determination of step...  
WO/2013/096898A3
Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunc...  
WO/2013/090837A3
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups,...  
WO/2013/090837A2
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups,...  
WO/2013/080219A3
The present invention relates to an improved process for the preparation of compound of Formula-II, which is an intermediate in the preparation of HMG-CoA reductase inhibitors. wherein X is hydrogen or hydroxy protecting group and Ri is ...  

Matches 151 - 200 out of 8,515