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WO/2010/072600 |
The present invention relates to a novel method for selectively isolating polyketide biosynthesis genes from metagenomes. Furthermore, the nucleic and amino acid sequences of the PKS cluster of psymberin and expression systems for produc...
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WO/2010/073404 |
The purpose of this object is to provide a valuable use of cashew apple. Another purpose of this object is to provide an active ingredient which originates in a natural material and has useful activities such as an α-amylase inhibitory ...
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WO/2010/068756 |
There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula (I) comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The inventio...
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WO/2010/068756 |
There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula (I) comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The inventio...
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WO/2010/053950 |
The present invention relates to microorganisms capable of producing isolable amounts of styrene and/or 7-methyl-l,3,5-cyclooctatriene (MCOT) and uses thereof. The present invention also relates to methods for biosynthetically preparing ...
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WO/2010/053950 |
The present invention relates to microorganisms capable of producing isolable amounts of styrene and/or 7-methyl-l,3,5-cyclooctatriene (MCOT) and uses thereof. The present invention also relates to methods for biosynthetically preparing ...
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WO/2010/046713 |
A process for preparing an enantiomerically enriched compound containing a substituted heterocyclic ring, said process comprising a carbon-carbon bond formation reaction in the presence of a crotonase superfamily protein or a homolog or ...
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WO/2010/046713 |
A process for preparing an enantiomerically enriched compound containing a substituted heterocyclic ring, said process comprising a carbon-carbon bond formation reaction in the presence of a crotonase superfamily protein or a homolog or ...
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WO/2010/046915 |
The present invention provides a method for pretreatment of agricultural residue. The method uses physical and mechanical means to change floating nature of the agricultural residue to a bottom settling sludge and enables to form slurry ...
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WO/2010/043748 |
A procedure is described for the obtainment of derivatives of monacolin J (I), wherein R1 is COR2, wherein R2 is selected from C1-C15 alkyl, C3-C15 cycloalkyl, C2-C15 alkenyl, C2-C15 alkynyl, aryl and heterocyclyl, comprising the product...
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WO/2010/041943 |
The invention relates to a method for preparing ε-caprolactam comprising deacylating N-acyl-6-aminocaproic acid and forming ε-caprolactam. The deacylation may be carried out chemically or biocatalytically. The invention further relates...
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WO/2010/041269 |
The present invention discloses an isolation and purification process for mycophenolic acid obtained from the fermentation process. Invention further discloses preparation of sodium salt of mycophenolic acid and mycophenolate mofetil fro...
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WO/2010/041943 |
The invention relates to a method for preparing ε-caprolactam comprising deacylating N-acyl-6-aminocaproic acid and forming ε-caprolactam. The deacylation may be carried out chemically or biocatalytically. The invention further relates...
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WO/2010/038842 |
Disclosed is a compound represented by formula (I) [wherein the symbols are as defined in the description]. Also disclosed is a process for producing the compound. The compound has a lipase-inhibiting activity, and is therefore useful ...
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WO/2010/034243 |
Novel isolated DNA sequences which comprise all or part of a gene cluster encoding sanglifehrin synthase, processing and regulatory genes involved in the biosynthesis of a mixed non-ribosomal peptide/ polyketide compound, or mutants havi...
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WO/2010/030197 |
A method for producing an algal biomass that readily separable from water, and preferably sterile, the method comprising heating an aqueous slurry of algae comprising a mixture of an algal biomass, optionally together with a suitable sep...
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WO/2010/030196 |
A method for processing biomass comprising heating an aqueous slurry comprising biomass, water and a phosphate catalyst in a pressure vessel at a temperature of about 150 °C to about 500 °C to produce a mixture comprising a dispersion ...
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WO/2010/026873 |
Disclosed are: a novel compound having an excellent inhibitory activity against at least one of a neutral ceramidase and an alkaline ceramidase; a process for producing the compound; a novel microorganism capable of producing the novel c...
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WO/2010/023725 |
Disclosed are: a novel compound which exhibits an excellent antibacterial activity against a wide variety of pathogenic bacteria including drug-resistant bacteria and plant-disease-causing bacteria, or exhibits an inhibitory activity aga...
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WO/2010/024445 |
An optically active amine derivative can be produced by: reacting an imine derivative with a culture or a cell of a microorganism capable of reducing the compound stereoselectively or a treatment product of the culture or the cell to the...
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WO/2010/023725 |
Disclosed are: a novel compound which exhibits an excellent antibacterial activity against a wide variety of pathogenic bacteria including drug-resistant bacteria and plant-disease-causing bacteria, or exhibits an inhibitory activity aga...
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WO/2010/024444 |
A novel enzyme capable of reducing an imine derivative stereoselectively is isolated and purified, and a polynucleotide encoding the enzyme is cloned. An optically active amine derivative can be produced by: reacting an imine derivative...
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WO/2010/022244 |
The invention provides methods and compositions for the production of L-ribitol and other rare sugars using a mannitol-1-dehydrogenase or a polyol-1-dehydrogenase.
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WO/2010/012074 |
An isolated nucleic acid molecule cloned from Artemisia annua encodes an alcohol dehydrogenase (Adh1). Artemisia annua Adh1 enzymatically oxidizes artemisinic alcohol to artemisinic aldehyde. The nucleic acid molecule, and the enzyme enc...
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WO/2010/010955 |
Disclosed are an isolated novel polynucleotide containing a nucleotide sequence for coding at least one type of polypeptide that contributes to the biosynthesis of pyripyropene A, a recombinant vector containing said polynucleotide, and ...
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WO/2010/011882 |
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with 1 module, and a cytochrome P450 hydroxylase is described. Also provided are novel Streptomyces species and metho...
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WO/2010/004584 |
The present invention provides treatment of diabetes using serpentine. The present invention particularly provides a process of production of serpentine in Catharanthus roseus hairy root culture, effect of hairy root extract in reducing ...
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WO/2010/003304 |
Recombinant bacteria for producing deoxyviolacein and uses thereof are provided, wherein the recombinant bacteria is obtained by introducing the deoxyviolacein synthesis-related gene cluster into Escherichia coli BL21-CodonPlus (DE3)-RIL...
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WO/2010/004584 |
The present invention provides treatment of diabetes using serpentine. The present invention particularly provides a process of production of serpentine in Catharanthus roseus hairy root culture, effect of hairy root extract in reducing ...
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WO/2010/003970 |
The present invention concerns highly water-soluble phenoxazines dyes of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claim, with improved photochemical properties, low toxicity, and favourable solubility...
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WO/2010/000676 |
The present invention relates to a method for preparing microbiologically produced ergot alkaloids of the following formula (I), comprising the step of: a) extracting the fermentation product occurring during the biological production, s...
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WO/2010/000839 |
This invention relates to improved processes for the production of lipstatin and/or orlistat and means therefore. In particular, the invention relates to microorganisms characterized by abolished or reduced activity of the BKD complex, e...
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WO/2010/000601 |
The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes particip...
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WO/2009/151728 |
The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective a...
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WO/2009/151530 |
The present invention generally relates to methods for treating tuberculosis in a subject comprising administering to the subject an antibiotic in conjunction with clavulanic acid or salt thereof. The antibiotic can be carbapenem (e.g., ...
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WO/2009/147984 |
The nucleotide sequence for DNA involved in the biosynthesis of herboxidiene is determined. By using the DNA, it becomes possible to produce herboxidiene and analogues thereof with high efficiency.
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WO/2009/142490 |
The invention relates to a method for preparing ε-caprolactam comprising reducing the carbon-carbon double bond of (Z)-6,7-dihydro-1H-azepin-2(5H)-one, wherein the reduction is catalysed by a biocatalyst.The invention further relates to...
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WO/2009/142489 |
The present invention relates to a method for preparing α-amino-ε-caprolactam, comprising converting lysine to α-amino-ε-caprolactam, wherein the conversion is catalysed by a biocatalyst. Further, the invention relates to a host cell...
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WO/2009/142489 |
The present invention relates to a method for preparing α-amino-ε-caprolactam, comprising converting lysine to α-amino-ε-caprolactam, wherein the conversion is catalysed by a biocatalyst. Further, the invention relates to a host cell...
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WO/2009/138994 |
The present invention demonstrates the utilization of halide anions such as iodates, periodates, bromates, chlorates, perchlorates and other forms of halides as supplements in fermentation media for the production of secondary metabolite...
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WO/2009/133096 |
The present invention relates to a method for the identification of one or more genes of a parent microbial strain capable of producing one or more desired β-lactam compound(s) and to mutant microbial strains in which the identified gen...
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WO/2009/134899 |
The present invention provides for a non-naturally occurring polyketide synthase (PKS) capable of synthesizing a carboxylic acid or a lactone, and a composition such that a carboxylic acid or lactone is included. The carboxylic acid or l...
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WO/2009/133096 |
The present invention relates to a method for the identification of one or more genes of a parent microbial strain capable of producing one or more desired β-lactam compound(s) and to mutant microbial strains in which the identified gen...
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WO/2009/131264 |
Disclosed herein is a method for preparing ortho- dihydroxyisof lavones using a biotransformation system. More specifically, disclosed is a method for preparing ortho-dihydroxyisof lavones, which comprises biotransf orming daidzein or ge...
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WO/2009/130706 |
The present invention is successful in providing a suitable process for the isolation and purification of geldanamycin. The process provided in the instant invention is easy to scale-up, industrially safe and will give high yield and pro...
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WO/2009/121495 |
Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.
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WO/2009/119111 |
Disclosed is a method for cheaply and easily producing theaflavins. After adding a large quantity of water to raw tea leaves that have not undergone wilt treatment, the tea leaves are crushed in a blender and then let stand, shaken, or a...
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WO/2009/118743 |
The invention provides a process for the production of lipase inhibitors via an improvised fermentation process characterized in that a combinatorial feeding of linoleic acid or its esters or salts thereof and an omega-9 fatty acid, pref...
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WO/2009/118750 |
The present invention provides a stereoselective enzymatic process for the resolution of a mixture of (±)-cis-3-acetoxy-1-(4-methoxyphenyl)-4-(2-furanyl)-2- azetidinone, (±)-cis-3-acetoxy-1-(4-methoxyphenyl)-4-(2-thiophenyl)-2-az
etidi...
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WO/2009/113855 |
The invention relates to a method for preparing 6-aminocaproic acid (hereinafter also referred to as '6-ACA')usinga biocatalyst. The invention further relates to a method for preparing e-caprolactam (hereafter referred to as 'caprolactam...
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