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Matches 1 - 50 out of 8,647

Document Document Title
WO/2019/007146A1
Provided are an aminotransferase, a mutant, and applications of the aminotransferase and the mutant in preparation of sitagliptin. According to the applications, bacteriophages obtained by performing fermentation culture on recombinant e...  
WO/2019/001548A1
Provided is a method for preparing fucoxanthin by fermental cultivation of Nitzschia laevis, comprising the following process steps: step A: preparation of a seed solution; step B: fermental cultivation: transferring the seed solution to...  
WO/2018/229306A1
The invention relates to recombinant host cells that expresses one or more genes encoding a cytochrome P450 enzyme capable of N-demethylating and/ O-demethylating reticuline and/or derivatives thereof, and also methods of producing a N-d...  
WO/2018/229305A1
The invention relates to norcoclaurine synthases and substrate binding sites having one or more site-specific mutation which increase the activity, when compared to the wild type synthase, of the condensation of 4-HPAA and dopamine to (S...  
WO/2018/229322A1
The present invention relates to an enzymatic composition and the development of an enzymatic cascade for the production of 2,5-furanodicarboxylic acid (FDCA) from 5-methoxymethylfurfural (MMF). The cascade is triggered by oxidation of M...  
WO/2018/218903A1
A method for preparing troxerutin ester using whole cell catalysis, which falls within the fields of biological catalysis and pharmaceutical chemistry. The method specifically comprises the following steps: evenly mixing troxerutin and a...  
WO/2018/217855A1
The present disclosure includes genetically engineered, non-pathogenic Streptomyces bacterium with exogenous, non-native Thaxtomin A (ThxA) biosynthetic gene clusters conferring the genetically engineered, non-pathogenic Streptomyces bac...  
WO/2018/212626A1
The present invention relates to a recombinant microorganism having an enhanced ability to produce heme, coproporphyrin III (Copro III), and uroporphyrin III (Uro III), and a method for producing heme, coproporphyrin III, and uroporphyri...  
WO/2018/212624A1
The present invention relates to a 11-lipoxygenase consisting of the amino acid sequence represented by SEQ ID NO: 1; or a composition for producing 11-hydroxyfatty acid, hepoxilin D3, or trioxilin D3, comprising the 11-lipoxygenase and ...  
WO/2018/207930A1
A recombinant microorganism is provided which has a gene encoding pyridoxine oxidase and a gene encoding pyridoxamine synthetase having enzymatic activity for synthesizing pyridoxamine from pyridoxal, wherein the gene encoding pyridoxine...  
WO/2018/207931A1
A recombinant microorganism is provided which has a gene encoding pyridoxine dehydrogenase, a gene encoding pyridoxamine synthetase having enzymatic activity for synthesizing pyridoxamine from pyridoxal, and a gene encoding an amino acid...  
WO/2018/207888A1
The present invention provides a method for simply and efficiently producing ramelteon, which is a sleep-inducing agent. According to the present invention, ramelteon can be produced through a few steps including a step in which (E)-2-[1...  
WO/2018/205563A1
A method for producing tetrahydropyrimidine by fermenting recombinant Corynebacterium glutamicum. The recombinant Corynebacterium glutamicum is obtained by overexpressing, in Corynebacterium glutamicum, an aspartokinase gene lysC of whic...  
WO/2018/206590A1
The invention provides a novel class of natural azaphilone pigments, called atrorosins, and methods for their production. The methods for the production of atrorosins include production by fermentation using a fungal species belonging to...  
WO/2018/205846A1
A method for extracting highly-effective natural plant anthocyanidin, which relates to the technical field of bioengineering. The method comprises the steps of: hydrolyzing anthocyanin; by using sodium bicarbonate or potassium bicarbonat...  
WO/2018/204859A1
In an aspect, the disclosure provides methods for making neurotransmitters in a host organism. The neurotransmitters can be cannabinoids and derivatives of cannabinoids. The host cells can be microalgae, fungi or other host cells. In a r...  
WO/2018/199814A1
The invention relates to microbiology and biotechnology. The unicellular algae strain Mallomonas kalinae SX-1 VKPM AI-23, a producer of fucoxanthin, a carotenoid having antioxidant activity, has been deposited at the Federally Funded Ins...  
WO/2018/200888A1
The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing...  
WO/2018/183706A8
The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (,S)-Y-hydroxymethyl-a,P-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the inv...  
WO/2018/183706A1
The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (,S)-Y-hydroxymethyl-a,P-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the inv...  
WO/2018/172401A1
The invention relates to fungal cells for the production of FDCA. The fungal cell has genetic modification that reduces specific 2,5-furandicarboxylic acid (FDCA) decarboxylating monooxygenase activity in the cell, as compared to a corre...  
WO/2018/169055A1
It is known that foods containing a carbohydrate, e.g., starch, in a large amount generate acrylamide upon heating at high temperatures. Some documents state that acrylamide is formed by the Maillard reaction of an amino acid, e.g., aspa...  
WO/2018/159957A1
The present invention relates to a method for selective and effective synthesis of equol, dehydroequol, 5-hydroxy-equol, and 5-hydroxy-dehydroequol from daidzein or genistein, using recombinant Escherichia coli bacteria in which Slackia ...  
WO/2018/154048A1
The invention provides an improved method of isolating the 3-(E)-isomer of an unsaturated carboxylic acid from a mixture of corresponding (E/Z)isomers. More particularly, the present invention relates to an improved method for the biocat...  
WO/2018/157021A1
A Squalene Hopene Cyclase (SHC) isolated from Gluconobacter morbifer is provided as are variants and a method for using the G. morbifer SHC to biocatalytxcally convert homofarnesol to ambroxan.  
WO/2018/149282A1
Disclosed is a method for heterologous expression of an epothilone, comprising introducing an epothilone gene cluster into host bacteria, while supplementing an epothilone precursor synthesis pathway combining with the introduction of th...  
WO/2018/148848A1
A method and cell line for producing phytocannabinoids and phytocannabinoid analogues in yeast. The method applies, and the cell line includes, a yeast cell transformed with a polyketide synthase CDS and a cytosolic prenyltransferase CDS...  
WO/2018/145342A1
Disclosed in the present invention is a method for preparing dihydrodaidzein, comprising the following steps: (1) using the compound represented by formula I as a raw material for an oxidation reaction to prepare a compound represented b...  
WO/2018/142109A1
The present invention relates to a process of producing a monoterpene and/or derivatives thereof. The process comprises the steps of: a) providing a host microorganism genetically engineered to express a bacterial monoterpene synthase (m...  
WO/2018/136654A1
Disclosed herein are methods for N-demethylating an N-methylated compound using an enzymatic reaction, rather than, e.g. a chemical modification. Also provided herein are enzymes for performing the reaction.  
WO/2018/133114A1
A novel 2, 2' -bipyridyl oxime, kibdelomycin A was isolated from the broth culture of a rare actinomycete strain Kibdelosporangium phytohabitans XY-R10. Its structure was established by extensive 1D and 2D NMR and high-resolution mass sp...  
WO/2018/130682A1
The present application provides a safe, efficient, environmental friendly and convenient method for an enzyme assisted lipid-based extraction and stabilization of phyto-cannabinoids and terpenes/terpenoids from plant materials. The lipi...  
WO/2018/126610A1
A genetically engineered bacterium for producing tetrahydropyrimidine by induction using xylose, a construction method therefor, and an application thereof. The strain is obtained by heterologously expressing an ectABC gene cluster from ...  
WO/2018/122510A1
The invention relates to a method for synthetising functionalised cyclic dithiocarbamates of formula (I), in which the various substituents are as defined in the description, by reacting a compound of formula (II): G-(CH2)n-C*H(NHR1)-X-R...  
WO/2018/123467A1
An indoloquinazoline compound represented by a specific structure. Clones having exceptional AI activity were detected by metagenomic analysis, and a novel indoloquinazoline compound synthase was identified from the clones. The novel ind...  
WO/2018/124135A1
The present invention addresses the problem of providing a method for eliminating the hydroxyl group at the 9-position of an urolithin in order to produce another urolithin. This problem is solved by a method for producing a second uroli...  
WO/2018/113476A1
The present invention provides a genetically engineered bacterium of coexpressing cyclohexanone monooxygenase and isopropanol dehydrogenase and use thereof, and the genetically engineered bacterium constructed can catalyze and convert hi...  
WO/2018/110799A1
Provided are a compound represented by any one of chemical formulas 1 to 3, or an isomer, derivative, solvate, or pharmaceutically acceptable salt thereof, a production method therefor, and a use thereof. According to this, antibacterial...  
WO/2018/103409A1
Disclosed are a methylocystis and the use thereof in the selective resolution and preparation of (S)-α-ethyl-2-oxo-1-pyrrolidine acetates. After cell immobilization of the enzyme-producing methylocystis, the methylocystis is applied to ...  
WO/2018/091885A1
The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 3, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound.  
WO/2018/090891A1
Disclosed are a dipyridyl alkaloid, a preparation method therefor and a use thereof, the structure of the dipyridyl alkaloid is as shown in formula I. The dipyridyl alkaloid has a tumour cell proliferation inhibitory activity and can be ...  
WO/2018/079686A1
A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective ...  
WO/2018/075670A1
A method of demethylizing an opioid to a nor-opioid is provided. The method comprises contacting an opioid with at least one enzyme. Contacting the opioid with the at least one enzyme converts the opioid to a nor-opioid. A method of conv...  
WO/2018/074916A1
The present invention is in the field of production of carbapenem antibiotics by microorganisms, specifically bacteria. The present invention relates to an improved method for producing high levels of antibiotics, and specifically carbap...  
WO/2018/046104A1
The present invention relates to microorganisms or progeny thereof having biosynthetic capability to convert cycloalkanes and to produce lactones using complex composed of cytochrome P450 monooxygenase, two reductases ferredoxin (Fd) and...  
WO/2018/040372A1
Provided are a yeast and a method for catalyticaly synthesizing 2,5-dihydroxymethylfuran by using the same. The yeast is Meyerozyma guilliermondii SC 1103 deposited in the China Center for Type Culture Collection with CCTCC NO.M 2016144....  
WO/2018/042841A1
A SAMe-containing material having a high SAMe content can be obtained by a method which comprises: a heating/dissolving step for supplying water and brown sugar to a culture tank and dissolving the brown sugar by heating; a culture step ...  
WO/2018/036479A1
A genetically engineered strain of phenazine-1-carboxamide (PCN), a preparation method for same, and uses thereof. The genetically engineered strain specifically is a genetically engineered strain produced by knocking off either or both ...  
WO/2018/035249A1
The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.  
WO/2018/029338A1
A process for producing the gardenia blue pigment comprising treating geniposide with a glycosidase to obtain a hydrolysate, extracting the hydrolysate with a solvent and removing the solvent after the extraction to obtain a product comp...  

Matches 1 - 50 out of 8,647