Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 8,764

Document Document Title
WO/2019/213754A1
Methods for in-situ enzymatic transformation of petroleum hydrocarbons into value-added products, using downhole injection of at least one hydrolytic enzyme and optional additives.  
WO/2019/185646A3
A process for oxidising a substrate selected from hydroxymethylfurfural (HMF), diformylfuran (DFF), hydroxymethylfurancarboxylic acid (HMFCA) and formylfurancarboxylic acid (FFCA). Said process comprises mixing said substrate with catala...  
WO/2019/175607A9
The complex chemistry underlying the extensive transformations involved in terpene indole alkaloid synthesis makes identification of the biosynthetic genes challenging. The present invention relates to methods for producing a terpene ind...  
WO/2019/202038A2
Isosorbide-5-methacrylate was obtained by enzymatic catalysis with Lipozyme RM IM in a highly regioselective manner in up to 87% yield. The process uses readily available acyl donors (methacrylic anydride or vinyl methacrylate), is easil...  
WO/2019/204787A1
The present disclosure describes the engineering of microbial cells for fermentative production of histamine and provides novel engineered microbial cells and cultures, as well as related histamine production methods.  
WO/2019/197334A1
The present invention relates to a process for the production of a dyed biopolymer comprising the steps of providing at least one biopolymer-producing microorganism, providing at least one dye-producing microorganism, culturing said at l...  
WO/2019/197571A1
The present invention is directed to a process for the enantioselective biocatalytic preparation of 4-substituted 1-aminoindanes of general formula (S)-I: (l) and a process for the preparation of Ozanimod, preferably involving the enanti...  
WO/2019/196262A1
The present invention relates to the field of pharmaceutical synthesis, and in particularly relates to a preparation method for a hexahydrofuro-furan-ol derivative, and an intermediate of the derivative and a preparation method therefor....  
WO/2019/194287A1
The present invention provides a method for producing 13-hydroxy-9(Z)-octadecenoic acid, which is improved in productivity. More specifically, the present invention provides a method for producing 13-hydroxy-9(Z)-octadecenoic acid, which...  
WO/2019/194309A1
Provided is a novel production method that can produce alkaloids at higher efficiencies than conventional methods. The method for producing alkaloids comprising a step for expressing, in a Catharanthus plant of the family Apocynaceae and...  
WO/2019/191772A1
This disclosure relates to strategies for in vivo production of certain carbon-based products, for example, aminated aliphatic compounds having a carbon chain length of C5-C19. Specifically, 7-aminoheptanoic acid is produced using a tran...  
WO/2019/189388A1
Provided is a culturing method for efficiently proliferating equol-producing bacteria belonging to Coriobacteriaceae. The present invention relates to a method for culturing equol -producing bacteria belonging to Coriobacteriaceae in an ...  
WO/2019/185646A2
A process for oxidising a substrate selected from hydroxymethylfurfural (HMF), diformylfuran (DFF), hydroxymethylfurancarboxylic acid (HMFCA) and formylfurancarboxylic acid (FFCA). Said process comprises mixing said substrate with catala...  
WO/2019/182440A1
The present invention is in the field of a method for producing engineered microorganisms, a method for producing cell wall-targeting antibiotics using said engineered microorganisms, and a product obtainable by said methods. The microor...  
WO/2019/157383A3
A method of producing promorphinan, morphinan, nal-opioid, and nor-opioid alkaloid products through the increased conversion of a promorphinan alkaloid to a morphinan alkaloid. The method comprises contacting the promorphinan alkaloid wi...  
WO/2019/174176A1
The present invention relates to the field of pharmaceutical synthesis, and in particularly relates to a preparation method for a hexahydrofuro-furan-ol derivative, and an intermediate of the derivative and a preparation method therefor....  
WO/2019/176732A1
[Problem] To provide a production method capable of easily synthesizing a compound having a structure in which a plurality of tetrahydroisoquinoline rings are linked together, using a reduced number of steps. [Solution] It was found that...  
WO/2019/175171A1
The present disclosure relates to a process for converting atranol and/or its derivatives into hydrosoluble compound(s). In particular, the present disclosure relates to a process for converting atranol and/or its derivative(s), said pro...  
WO/2019/175607A1
The complex chemistry underlying the extensive transformations involved in terpene indole alkaloid synthesis makes identification of the biosynthetic genes challenging. The present invention relates to methods for producing a terpene ind...  
WO/2019/169695A1
A bradyrhizobium monooxygenase, a gene for encoding the monooxygenase, a recombinant expression vector comprising the gene, a recombinant expression transformant, a method for preparing the monooxygenase by using the recombinant expressi...  
WO/2019/173797A1
Disclosed herein are prokaryotic and eukaryotic microbes, including E. coli and S. cerevisiae, genetically altered to biosynthesize tryptamine and tryptamine derivatives. The microbes of the disclosure may be engineered to contain plasmi...  
WO/2019/166093A1
A method for increased and permanent production of a natural compound by a microorganism during an exponential growth and during a stationary phase of a culture of the microorganism, the method comprising: enhancing a translation of a ta...  
WO/2019/165551A1
Disclosed are methods for converting a substrate into a product alkaloid, including a benzylisoquinoline compound or benzylisoquinoline precursor compound, in a biosynthetic system involving the growth of host cells. The cells comprise a...  
WO/2019/169334A1
The present disclosure provides methods for preparing tryptophans and tryptophan derivatives. The methods include: combining i) an indole substrate or azulene substrate, ii) a serine substrate, and iii) an engineered tryptophan synthase ...  
WO/2019/158513A1
The present invention is directed to methods for catalyzing a chemical reaction by retroaldolases, corresponding uses of retroaldolases and to novel retroaldolases. The methods and retroaldolases have utility in (i) preparing tertiary al...  
WO/2019/153633A1
Provided are an alcohol dehydrogenase mutant and an application thereof in synthesis of diaryl chiral alcohol, belonging to the technical field of the biological engineering. The alcohol dehydrogenase mutant has good catalytic activity a...  
WO/2019/157383A2
A method of producing promorphinan, morphinan, nal-opioid, and nor-opioid alkaloid products through the increased conversion of a promorphinan alkaloid to a morphinan alkaloid. The method comprises contacting the promorphinan alkaloid wi...  
WO/2019/153183A1
The present invention relates to the technical field of genetic engineering, and provides a monooxygenase mutant, a preparation method therefor and an application thereof. The monooxygenase mutant has any one of the amino acid sequences ...  
WO/2019/153634A1
An alcohol dehydrogenase mutant and an application thereof in the synthesis of biaryl chiral alcohol. The alcohol dehydrogenase in the present invention is coupled to glucose dehydrogenase or formate dehydrogenase, and may be used for th...  
WO/2019/153632A1
Provided are an alcohol dehydrogenase mutant and an application thereof in synthesis of diaryl chiral alcohol, belonging to the technical field of the biological engineering. The alcohol dehydrogenase mutant has good catalytic activity a...  
WO/2019/150564A1
The present invention pertains to a method for synthesizing an oligodeoxynucleotide (ODN), said method comprising synthesizing an ODN which has a sulfonamide bonded thereto via a non-natural internucleotide linkage and using the thus syn...  
WO/2019/144920A1
A method for promoting the fermentation of Gluconobacter oxydans to produce D-sorbitol dehydrogenase and pyrroloquinoline. The method is such that: Gluconobacter oxydans is grafted to a fermentation culture medium, fermented and cultured...  
WO/2019/147865A1
Methods for catalyzing C-H insertion reactions using heme enzymes are described. The present disclosure provides a method for producing a C-H insertion product comprising providing an substrate having an sp3-hybridized C-H bond, a carben...  
WO/2019/140682A1
Provided are a ketoreductase mutant and an application thereof. The amino acid sequence of the ketoreductase mutant is an amino acid sequence obtained by mutating the amino acid sequence shown in SEQ ID NO: 1, and the mutation comprises ...  
WO/2018/027324A9
This disclosure relates to the production of opium poppy plants having high levels of thebaine. More particularly, the disclosure relates to the production of opium poppies having high levels of thebaine by simultaneously reducing the ex...  
WO/2019/128387A1
The present invention provides a method for preparing (S)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid and a derivative thereof by using enzymatic resolution, the method comprising the step of: using racemic 1,2,3,4-tetrahydroisoquin...  
WO/2019/130681A1
The present invention addresses the problem of providing a method for removing the hydroxyl group at the 8-position of a urolithin to produce a different urolithin. The present invention solves this problem by means of a method for produ...  
WO/2019/128006A1
Provided are mold OMK-25 for producing delta-lactone and an application thereof. Mold OMK-25 was deposited in China Center for Type Culture Collection on June 14, 2017 under a collection number of CCTCC M 2017339. Provided is a route for...  
WO/2019/130448A1
The present invention addresses the problem of providing a method for removing the hydroxyl group at the 8-position of a urolithin to produce a different urolithin. The present invention solves this problem by means of a method for produ...  
WO/2019/122421A1
The present application relates to processes for stereo- and regioselective reduction of cyclohexanones using a ketoreductase enzyme. Compounds prepared according to the disclosed processes are useful in the preparation of compounds for ...  
WO/2019/120132A1
A biosynthetic gene cluster-dis427 of Disorazole Z, the nucleotide sequence thereof is as shown in SEQ ID No. 1. An engineered strain DK1622::Km-Ptet-dis427 for heterologous expression of Disorazole Z is constructed by utilizing the gene...  
WO/2019/113710A1
Disclosed are methods for converting a substrate into a product benzylisoquinoline compound in a biosynthetic system involving the culturing of cells in a medium. The cells comprise a benzylisoquinoline uptake permease and a biosynthetic...  
WO/2019/117612A1
The present invention relates to a microorganism variome which is capable of extracellular heme generation, and more specifically, to a metabolically engineered microorganism variome which is capable of extracellular heme generation and ...  
WO/2019/109170A1
Disclosed are methods for converting a first morphinan alkaloid compound into a second morphinan alkaloid compound in the presence of a neopinone isomerase enzyme under reaction conditions permitting the conversion of the first alkaloid ...  
WO/2019/098598A1
The specification relates to a method for producing coumestrol by using cultured roots of leguminous plants and a method for preparing a leguminous plant extract having an increased coumestrol amount. A method according to one aspect of ...  
WO/2019/013573A9
The present invention suggests: a newly shown biosynthesis pathway using the production of homoserine as an intermediate stage for the preparation of 2-hydroxy gamma butyrol acetone (HGBL) and a precursor thereof, 2,4-dihydroxybutanoic a...  
WO/2019/076021A1
Provided is a preparation method for hesperetin, comprising: suspending hesperidin or neohesperidin in water, and adding a sodium hydroxide solution until the hesperidin or neohesperidin is completely dissolved to obtain a substrate prep...  
WO/2019/032235A3
The present invention relates to the production of eriodictyol via bioconversion.  
WO/2019/071000A1
Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ9-tetrahydrocannabinolic acid (THCA), cannabidiolic ac...  
WO/2019/070992A1
Metastable state spore incubation mixing systems are described. An example system includes a spore container to store spores, a nutrient container, an arrangement of valves and tubes, a reciprocating pump, a mixing tube, and a holding ta...  

Matches 1 - 50 out of 8,764