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Matches 1 - 50 out of 8,963

Document Document Title
WO/2020/262107A1
The present invention relates to a production method of (R)-reticulin comprising: a step for obtaining a recombinant host cell by inserting, to a host cell, a gene 1 which is composed of a nucleotide sequence having at least 70% homology...  
WO/2020/208411A3
Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ9-tetrahydrocannabinolic acid (THCA), cannabidiolic ac...  
WO/2020/254745A1
The present invention relates to a selective process for the preparation of sulfones from sulfides by enzymatic catalysis, as well as to a composition comprising a symmetrical sulfide, an oxidoreductase enzyme catalyzing the oxidation of...  
WO/2020/254744A1
The present invention relates to a selective process for preparing sulfoxides from sulfides by enzymatic catalysis, as well as to a composition comprising a symmetrical sulfide, wherein an oxidoreductase enzyme catalyzes the oxidation of...  
WO/2020/159298A3
The present invention relates to novel microalgae having high loliolide productivity. Scenedesmus sp. HS4 of the present invention has high biomass productivity and high loliolide content, thereby being usable as a biological resource ca...  
WO/2020/247976A1
Provided herein are methods and compositions related to forming cross-links between surfactant molecules at an interface between dispersed phase partitions and a continuous phase in an emulsion, and uses of such cross-linked emulsions.  
WO/2020/237552A1
Provided are a transaminase mutant and a method for producing chiral amines using the transaminase mutant. The amino acid sequence of the transaminase mutant is an amino acid sequence obtained after mutation occurs to the amino acid sequ...  
WO/2020/233506A1
A method for improving the production of streptomyces polyketide compounds is provided. The method greatly improves the capability of the streptomyces polyketide compounds by strengthening a triacylglycerol decomposition pathway in strep...  
WO/2020/232553A1
The present disclosure relates generally to methods and cell lines for the production of phytocannabinoids, phytocannabinoid precursors or intermediates, or phytocannabinoid analogue. Methods for transformation of host cells, such as yea...  
WO/2020/234215A1
The present invention relates to a biological cell that can grow in the absence of biotin under aerobic conditions, comprising a BIO1 gene (i.e. CfBIO1), and preferably a BIO6, BIO2, BIO3, and BIO4 gene. The present disclosure additional...  
WO/2020/229516A1
Herein are provided microbial factories, in particular yeast factories, for production of strictosidine aglycone and optionally other plant-derived compounds. Also provided are methods for producing strictosidine aglycone in a microorgan...  
WO/2020/230833A1
The purpose of the present invention is to provide a novel compound which has the action of effectively enhancing the antifungal activity of an antifungal drug and which has a skeleton structure different from that of known pharmaceutica...  
WO/2020/221795A1
The present invention relates to microbial factories, in particular yeast factories, for production of ergothioneine. Also provided are methods for producing ergothioneine in a yeast cell, as well as useful nucleic acids, polypeptides, v...  
WO/2020/219859A1
Disclosed are trans-enoyl CoA reductase (TER) enzymes and nucleic acids encoding them. In some cases, the TER enzymes are non- natural, engineered trans-enoyl CoA reductase. TER enzymes were shown to catalyse the conversion of 5-carboxy-...  
WO/2020/219863A1
Disclosed are biosynthetic methods and engineered microorganism that enhance or improve the biosynthesis of hexamethylenediamine, caproic acid or caprolactam. The engineered microorganisms include selected aldehyde dehydrogenase activity.  
WO/2020/212453A1
The invention relates to the use of an aldolase when carrying out a process comprising multiple successive crossed aldol reactions.  
WO/2020/211013A1
Disclosed are a monooxygenase mutant and use thereof. The amino acid sequence of the monooxygenase mutant is an amino acid sequence obtained by mutating the amino acid sequence as shown in SEQ ID NO: 1. The mutation comprises at least on...  
WO/2020/206051A1
Described herein is a method for producing indole-3-propionic acid and other indole derivatives via bacterial fermentation and compositions of the same. The method comprises adding bacteria Clostridium sporogenes ATCC15579 having a nucle...  
WO/2020/192560A1
The present invention discloses a chiral isoquinoline carboxylic acid (Ⅰ) and a preparation method thereof, the preparation method includes: reacting the racemate of isoquinoline carboxylate in an aqueous buffer solution under the cata...  
WO/2020/185626A1
Provided herein, among other things, is an engineered non-plant cell that produces a tropane alkaloid product, a precursor of a tropane alkaloid product, or a derivative of a tropane alkaloid product. A method for producing a tropane alk...  
WO/2020/177568A1
The present invention relates to an LL-D49194α1 analog, a preparation method therefor and an application thereof. Specifically, provided by the present invention is a deglycosylated and demethylated LL-D49194α1 analog. The obtained LL-...  
WO/2020/180736A2
The present invention provides methods and compositions for producing cannabinoids in photosynthetic microorganisms, e.g., cyanobacteria.  
WO/2020/176958A1
The present disclosure provides recombinant microorganisms and methods for the production of 4-HMF, 2,4-furandimethanol, furan-2,4-dicarbaldehyde, 4-(hydroxymethyl)furoic acid, 2-formylfuran-4-carboxylate, 4-formylfuran-2-carboxylate, an...  
WO/2020/176998A1
Provided herein are methods and compositions for producing cannabinoids and other metabolites in a host cell.  
WO/2020/127208A3
The present disclosure concerns the large-scale manufacture of pharmaceutical compounds, and novel intermediates for use in the manufacture. International Patent Application WO2011154737 discloses morpholine pyrimidines useful for treati...  
WO/2020/177390A1
A method for preparing an L-ergothioneine-containing cosmetic stock solution by means of fermenting Hericium erinaceus, the method comprising the following steps: step 1: inoculating Hericium erinaceus hyphae into a liquid seed culture m...  
WO/2019/233367A8
A streptomyces strain and an application thereof, and a method for preparing staurosporine by culturing the strain. The strain is named as streptomyces sp. HS-HY-153, and the preservation number thereof is CGMCC NO. 14806.  
WO/2020/173977A1
A method for making 2-oxygenated decalins form isoprenoids catalysed with a squalene-hopene cyclase (SHC). A fragrance composition comprising (2S*,4aS*,8aR*)-5,5,8a- trimethyldecahydronaphthalen-2-yl acetate.  
WO/2020/173453A1
Disclosed is a method for resolving an optical isomer from a racemate by means of electrodialysis. Specifically, an electrodialysis technique is used in an enzymatic resolution process, mainly in the separation of products after enzymati...  
WO/2020/172438A1
The present invention provides for a genetically modified fungal host cell capable of producing indigoidine, wherein the host cell comprises a non-ribosomal peptide synthetase (NRPS) that converts glutamine to indigoidine.  
WO/2020/165178A1
The invention relates to a recombinant yeast modified to be capable of producing eriodictyol and/or luteolin and to the use thereof to produce eriodictyol and/or luteolin.  
WO/2020/165882A2
The present invention relates to a method of producing high-purity 2-pyrone-4,6-dicarboxylic acid (PDC), and a method of producing an intermediate for same, the methods comprising the steps of: 1) producing terephthalic acid (TPA) from P...  
WO/2020/165182A1
The invention relates to a recombinant microorganism modified to be capable of producing diosmetin and/or hesperetin and to the use thereof to produce diosmetin and/or hesperetin.  
WO/2020/165189A1
The present invention relates to a recombinant microorganism modified to be capable of producing diosmin and hesperidin and to the use thereof for producing diosmin and/or hesperidin.  
WO/2020/162442A1
Provided are: a novel compound having antibacterial activity; and a method for producing the same. The present invention relates to a compound represented by formula (I), or a salt or ester thereof.  
WO/2020/163378A1
The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabi...  
WO/2020/161280A1
The present invention relates to a method for culturing unicellular red algae (URA) optimized for the valorization of culture products, both the biomass obtained and the phycocyanins which are extracted or the other culture products such...  
WO/2020/161682A1
The present invention relates to genetically modified ascomycetous filamentous fungi, particularly of the species Thermothelomyces heterothallica capable of producing cannabinoids and precursors thereof, particularly of producing cannabi...  
WO/2020/041851A3
The present invention relates to a pharmaceutical composition comprising secondary metabolites produced by the fungus Exserohilum rostratum for cell regeneration. Particularly, the present invention relates to a pharmaceutical compositio...  
WO/2020/147031A1
Disclosed are a nitrile hydratase mutant, a genetically engineered bacterium containing the mutant, and the use thereof, falling within the technical field of enzyme engineering. According to the present invention, glycine at position 47...  
WO/2020/121324A3
The present invention relates to a fermentation process for the synthesis of Nigericin from Streptomyces sp. having accession number MCC 0151 and its isolation with high yield. The present invention further relates to a microbial inocula...  
WO/2020/109776A3
A method for the use of a cytochrome P450 enzyme comprising any of SEQ ID NO: 1 -118, or mutants thereof or a variant enzyme having at least 70% identity thereto and having CYP450 activity, for the hydroxylation and or dealkylation of an...  
WO/2020/144371A1
The present invention relates to a recombinant microbial host cell comprising an operative biosynthetic metabolic pathway capable of producing one or more compounds selected from the group consisting of L-dopa, dopamine, (S)-Norcoclaurin...  
WO/2020/141230A1
The present invention relates to arecombinant microbial host cell producing a tetraketide or derivatives thereof from one or more substrates selected from cinnamoyl-CoA, p-Coumaroyl-CoA, Caffeoyl-CoA, Feruloyl-CoA, malonyl-CoA, sinapoyl-...  
WO/2020/137706A1
[Problem] The purpose of the present invention is to provide a new method for producing a cycloastragenol analog from astragaloside IV. {Solution] A method for producing a cycloastragenol analog that includes a contact step that brings a...  
WO/2020/134727A1
The present invention discloses a tetrapeptide compound, a preparation method and a use thereof. The tetrapeptide compound of the present invention is TP represented by formula 1, the preparation method thereof is firstly preparing an in...  
WO/2020/127208A2
The present disclosure concerns the large-scale manufacture of pharmaceutical compounds, and novel intermediates for use in the manufacture. International Patent Application WO2011154737 discloses morpholine pyrimidines useful for treati...  
WO/2020/128434A1
Disclosed herein is a method of reducing an aromatic nitro compound. In some embodiments the method comprises the step of (i) contacting an aromatic nitro compound with a catalyst, wherein, the catalyst comprises: (a) disproportionation ...  
WO/2020/122609A1
The present invention relates to the production of a novel compound usable as a main ingredient of a pharmaceutical composition for preventing or treating neurological disorders, the compound being 9-deoxo-31-O-demethyl-prolyl-FK506, 9-d...  
WO/2020/119828A1
Disclosed are an ectoine-producing Bacillus clausii ET01 and a method for producing ectoine by means of fermentation using the strain. The strain is deposited in the China General Microbiological Culture Collection Center (CGMCC) with th...  

Matches 1 - 50 out of 8,963