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Matches 1 - 50 out of 8,568

Document Document Title
WO/2018/046104A1
The present invention relates to microorganisms or progeny thereof having biosynthetic capability to convert cycloalkanes and to produce lactones using complex composed of cytochrome P450 monooxygenase, two reductases ferredoxin (Fd) and...  
WO/2018/040372A1
Provided are a yeast and a method for catalyticaly synthesizing 2,5-dihydroxymethylfuran by using the same. The yeast is Meyerozyma guilliermondii SC 1103 deposited in the China Center for Type Culture Collection with CCTCC NO.M 2016144....  
WO/2018/042841A1
A SAMe-containing material having a high SAMe content can be obtained by a method which comprises: a heating/dissolving step for supplying water and brown sugar to a culture tank and dissolving the brown sugar by heating; a culture step ...  
WO/2018/036479A1
A genetically engineered strain of phenazine-1-carboxamide (PCN), a preparation method for same, and uses thereof. The genetically engineered strain specifically is a genetically engineered strain produced by knocking off either or both ...  
WO/2018/035249A1
The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.  
WO/2018/029338A1
A process for producing the gardenia blue pigment comprising treating geniposide with a glycosidase to obtain a hydrolysate, extracting the hydrolysate with a solvent and removing the solvent after the extraction to obtain a product comp...  
WO/2018/029282A1
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductases thereby increasing the production of benzylisoqui...  
WO/2018/027324A1
This disclosure relates to the production of opium poppy plants having high levels of thebaine. More particularly, the disclosure relates to the production of opium poppies having high levels of thebaine by simultaneously reducing the ex...  
WO/2018/015512A1
The invention relates to recombinant microorganisms and methods for producing 13R-MO and/or 13R-MO derivatives, including forskolin.  
WO/2018/012426A1
Provided is a method for efficiently producing mucic acid from a commonly used organic raw material such as glucose or galactose. Provided is a method for producing mucic acid in which glucose or galactose is used as a starting material ...  
WO/2018/002379A3
The invention relates to use of a peroxygenase for preparing indigo dyes and an in situ method for dyeing a textile with indigo dyes.  
WO/2018/005806A2
The present disclosure relates to biosynthetic pathways for producing flavor and fragrance chemicals, such as green notes including trans-2-unsaturated aldehydes and lactones. The present disclosure provides methods for producing trans-2...  
WO/2018/000089A1
Polynucleotides and polypeptides useful in the manufacture of a class of chemical compounds known as alkaloids are provided. The polynucleotides and polypeptides may be used to synthesize alkaloids, including reticuline, thebaine and mor...  
WO/2018/002379A2
The invention relates to use of a peroxygenase for preparing indigo dyes and an in situ method for dyeing a textile with indigo dyes.  
WO/2017/214159A1
The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.  
WO/2017/213758A1
The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered prolin...  
WO/2017/214423A8
In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed here...  
WO/2017/214423A3
In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed here...  
WO/2017/202897A1
Described herein are variants of acetylserotonin O-methyltransferase (ASMT) as well as vectors and recombinant microbial host cells expressing such ASMT variant and their use in producing melatonin and related compounds. Preferred ASMT v...  
WO/2017/202193A1
Provided are applications of a recombinant ketoreductase in the preparation of (R)-3-quinuclidinol. The amino acid sequence of the recombinant ketoreductase is shown by any one of SEQ ID No.2, 4, 6, 8 and 10. A product is obtained in a r...  
WO/2017/203454A1
The invention relates to a method for obtaining an extract from a cell culture of Neem (Azadirachta indica). The suspended cell culture is subjected to cellular stress under conditions that promote the production of active metabolites su...  
WO/2017/197993A1
Provided are a Serratia liquefaciens ZMT-1 the collection No. of which is CCTCC NO:M2016170, and a method for producing Heliotropin by using the Serratia liquefaciens ZMT-1 strain or an enzyme produced by the Serratia liquefaciens ZMT-1 ...  
WO/2017/182542A1
A solid form of (-)-Ambrox formed by a bioconversion process.  
WO/2017/178624A1
The present invention relates to a method to improve the production of a secondary metabolite catalyzed by a non-ribosomal peptide synthetase comprising contacting in a eukaryotic host a eukaryotic non-ribosomal peptide synthetase with a...  
WO/2017/175064A1
A method for the bio-enzymatic synthesis of tetrahydrocannabivarin (THC-v), cannabivarin (CBV) and cannabinol (CBN) by contacting a compound according to Formula I with a cannabinoid synthase enzyme. The cannabinoids are produced in the ...  
WO/2017/167866A1
Described herein are recombinant microbial host cells comprising biosynthetic pathways and their use in producing oxidation products and downstream products, e.g., melatonin and related compounds, as well as enzyme variants, nucleic acid...  
WO/2017/165692A1
The present disclosure provides compounds linked with a saccharide-metal complex. The compounds are designed to protect organs by inducing acquired cytoresistance without causing injury to the organ, among other potential uses.  
WO/2017/155025A1
Provided is a method for producing compound (1) or (6) by optical resolution using a specific hydrolase. (In the formula, R represents a protecting group of a carboxy group, R1 and R2 each independently represent a hydrogen atom or a pro...  
WO/2017/152273A1
Methods that may be used for the manufacture of a class of chemical compounds known as terpenoid indole alkaloids, including tabersonine and catharanthine are provided. Compositions useful for the synthesis of terpenoid indole alkaloids,...  
WO/2017/155945A1
Methods and systems of cell-free enzyme discovery and optimization are provided.  
WO/2017/150304A1
Provided is a method for producing ergothioneine, the method being characterized in that microorganisms having the ability to produce ergothioneine are cultured and extracellularly produced ergothioneine is obtained, and the method being...  
WO/2017/144065A1
The present invention reports a method of producing complex guaianolides from the plant genus Thapsia. The invention comprises a temporary immersion bioreactor (TIB) and cultures conditions for mass micropropagation of Thapsia spp. The i...  
WO/2017/140909A1
The invention relates to methods for synthesizing sclareolide and related compounds by biocatalytic cyclisation of a polyunsaturated carboxylic acid compound, in particular homofarnesylic acid and related compounds. The invention also re...  
WO/2017/137606A1
The present invention relates to processes to make neosaxitoxin, and analogues and variants thereof, and intermediates in the production of neosaxitoxin in recombinant host cells. Neosaxitoxin and the analogues and variants thereof may b...  
WO/2017/129914A1
The invention relates to a method for producing pigments by cells capable of photosynthesis, according to which said cells are cultivated in conditions suitable for the development thereof, in order to obtain a biomass, the method compri...  
WO/2017/107897A1
The invention discloses preparation methods and use of an indole alkaloid compound. The invention produces a structural-novel indole alkaloid compound by using Penicillium crustosum PRB-2 collected from the deep ocean of Prydz Bay, Antar...  
WO/2017/108861A1
The invention provides a method for producing a flavoured milk product, the method comprising the steps of: (a) providing milk source; (b) fermenting the milk source using at least one microorganism, to produce a fermented milk source ha...  
WO/2017/103221A1
The invention provides a genetically modified bacterium for production of thiamine; where the bacterium is characterized by a transgene encoding a thiamine monophosphate phosphatase (TMP phosphatase having EC 3.1.3.-) as well as transgen...  
WO/2017/100429A1
Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feeds...  
WO/2017/092197A1
Provided in the present invention is a method for the enzymatic resolution of an isavuconazole intermediate. Enantiomeric impurities in (2R,3S)-isavuconazole intermediate I are hydrolyzed to (2S,3S)-carboxylic acid by-product by nitrilas...  
WO/2017/084064A1
Provided is a use of an electronic olfactory device in on-line detection of a cyclohexanecarboxylic acid concentration during dolomycin fermentation. An optimization method for supplementing a precursor during the dolomycin fermentation ...  
WO/2017/076273A1
Provided is a method for synthesizing pyrroloquinoline quinine in vitro by utilizing bacteria cell disruption supernatant and adding a pyrroloquinoline quinine synthesis precursor-artificially synthesized polypeptide. The method comprise...  
WO/2017/068217A1
The invention relates to a method for producing polyhydroxyalkanoates and ectoine from cereal grain hydrolysates by means of saccharification and simultaneous fermentation. The method uses liquefied cereal grain and allows polyhydroxyalk...  
WO/2017/055573A1
The present invention relates to genetically modified enzymes obtained by rational design of the active site binding pocket of the prototypic enzyme 4-hydroxyphenylacetate 3-hydroxylase (4HPA3H) for hydroxylating a 4-hydroxyphenyl compou...  
WO/2017/057730A1
The present invention addresses the problem of providing a novel method for suppressing the generation of hydroxy-L-proline and producing high-purity hydroxy-L-pipecolic acid efficiently and inexpensively. Provided is a method for genera...  
WO/2017/049751A1
Provided is a Dectomax fermentation production method on the basis of using an oxygen uptake rate (OUR) as a control parameter. In the fermentation production method, a two-stage OUR control strategy is used, the oxygen uptake rate (OUR)...  
WO/2017/050918A1
The invention relates to an acid composition, particularly an acid food composition, comprising at least one phycocyanin resistant to pH acid.  
WO/2017/052232A1
A recombinant Streptomyces avermitilis strain producing milbemycin, and a milbemycin production method using the same are provided.  
WO/2017/050853A1
Methods for producing anthocyanin by expression in a microorganism are disclosed including culturing of the microorganism under anthocyanin producing conditions, wherein the microorganism has an operative metabolic pathway including at l...  
WO/2017/046319A1
The present invention relates to an asymmetric process for providing N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)et hyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (apremilast) or a pharmaceutically acceptable salt or...  

Matches 1 - 50 out of 8,568