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JPS6270395A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS622798B2 |
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JPS61289889A |
PURPOSE: To produce a valuable substance using an enzyme, economically, preventing the deterioration of filtration membrane without lowering the rate of filtration, by filtering an enzymatic reaction liquid with an ultrafiltration membra...
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JPS6150955B2 |
This invention relates to certain novel alpha -amino- or alpha -formyl- alpha -(p-acyloxyphenyl)acetamidocephalosporanic acids which are useful as antibacterial agents.
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JPS61152298A |
PURPOSE: Immobilized penicillin acylase is allowed to act on an aqueous solution of an alkali metal salt of penicillin and the resultant hydrolyzate is specifically treated to give 6-aminopenicillanic acid free from discoloration during ...
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JPS61135580A |
A system for continuously monitoring the chemistry of a liquid medium within a container comprising an assaying means located exteriorly of the container, a conduit connected to the assaying means and leading to the container, a probe co...
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JPS6169792A |
A compound of formula I or a physiologically acceptable salt thereof (I) wherein X represents sulphur or methylene, R1 represents hydrogen, amino or an acylated or carbamylated amino group, R2 represents hydrogen or an alkyl group and R3...
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JPS616084B2 |
To chemically bind either impure or purified enzymes to polyurethane to produce insolubilized bound enzymes which are still enzymically active and which may be more stable than the original enzyme, and which can be reused without appreci...
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JPS60260585A |
This invention relates to certain novel alpha -amino- or alpha -formyl- alpha -(p-acyloxyphenyl)acetamidocephalosporanic acids which are useful as antibacterial agents.
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JPS6050795B2 |
A process for the preparation of penicillanic acetamido acids which consists of a) reacting a compound of the formula: ** (see formula) ** Or a silyl ester or a salt thereof, with an acylating agent of an acid of the formula: ** (see for...
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JPS6040832B2 |
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JPS60142993A |
A process for producing unnatural penicillins and cephalosporin derivatives thereof in which peptide analogs of ACV in which the L- alpha -aminodipyl moiety is replaced by L-S-carboxymethyl cysteine or other substituents, are reacted wit...
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JPS6022920B2 |
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JPS6094086A |
1. A process for the preparation of an immobilized acylase, wherein the enzyme is bound by means of a diisocyanate to a macroporous anion exchange resin based on phenol/formaldehyde and carrying essentially secondary amino groups.
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JPS6066981A |
Self-supported insoluble penicillinamidase prepared by cross-linking the exocellular amidase produced by B. megaterium with a dialdehyde followed by treatment with a salt containing a multivalent anion provides a superior hydrolytic cata...
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JPS6011423A |
A process is proposed for the isolation and purification of antibiotics wherein an antibiotic containing solution is extracted with an extraction agent at a temperature of from 0 DEG to 40 DEG C. and at a pressure which lies between the ...
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JPS59210891A |
The invention relates to an enzymatic process in which an immobilised biocatalyst containing an enzyme catalysing the formation of a proton generating product, and containing an enzyme catalysing the formation of a proton consuming produ...
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JPS5937079B2 |
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JPS5991895A |
The enzymes, cyclase, epimerase and a ring expansion enzyme, are isolated separately from a cell-free extract of a prokaryotic beta-lactam producing organism. The isolated enzymes are used to produce unnatural cephalosporins from polypep...
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JPS5915629B2 |
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JPS5931694A |
PURPOSE: To obtain high-quality 6-aminopenicillanic acid in high yield, by subjecting a solution containing a 6-aminopenicillate obtained by hydrolyzing a penicillin with an enzyme to a reverse osmosis membrane so that it is concentrated...
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JPS58212794A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS58190399A |
PURPOSE: To prepare 6-aminopenicillanic acid efficiently from penicillin by using an immobilized enzyme obtained by immobilizing penicillinacylase to a specific porous weakly basic anion exchange resin. CONSTITUTION: A porous weakly basi...
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JPS58149676A |
PURPOSE: To utilize the burnt ash of animal excrement which is a waste available from stock farms, as an inorganic source of a medium for the cultivation of microorganisms. CONSTITUTION: Excrement of cattle or poultry, such as chicken, p...
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JPS5838152B2 |
Novel re-usable water-insoluble penicillin acylase complexes are provided wherein a penicillin acylase is adsorbed on a water-insoluble polymer or co-polymer of methacrylic acid and cross-linked with a water-soluble aldehyde selected fro...
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JPS5829135B2 |
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JPS5879996A |
Plasmid pAC 1, which is obtained from Acremonium chrysogenum ATCC 14553 and has a contour length of about 6.7 mu m and a molecular size of about 20.9 kilobases (=kb), a process for obtaining it and its use for preparing a hybrid vector w...
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JPS588838B2 |
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JPS5756359B2 |
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JPS57170188A |
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JPS57501610A |
Method for carrying out biological and chemical conversion processes which require the presence of one or more catalytically active substances, such as enzymes, microorganisms, cells, organelles, cell homogenates, and organic or inorgani...
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JPS5741232B2 |
A method and apparatus for continuously circulating a mixture comprising a liquid and a gas around a system comprising a riser and a downcomer and a gas disengagement section in which liquid flows downwardly at a velocity which does not ...
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JPS57130986A |
NEW MATERIAL:6-Sulfaminopenicillanic acid of formula or its salt. USE: Antibacterial agent. It has β-lactamase-inhibitive action, and useful in the field of drug and animal drug. PROCESS: The 6-sulfaminopenicillanic acid of formula and ...
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JPS57105196A |
A process for the preparation of a compound of formula (I): (I) wherein R1 is hydrogen, hydroxy, mercapto radical, a substituted or unsubstituted methoxy, ethoxy, methyl, ethyl, methyl thio, or ethylthio radical, a carbamoyloxy, carbamoy...
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JPS5729154B2 |
Novel re-usable water-insoluble penicillin acylase complexes are provided wherein a penicillin acylase is adsorbed on a water-insoluble polymer or co-polymer of methacrylic acid and cross-linked with a water-soluble aldehyde selected fro...
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JPS5718477B2 |
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JPS5714837B2 |
After reaction with a cyanogen halide, polysaccharides form a water-soluble support for penicillin acylase. Due to its high stability, the polymer-bound penicillin acylase can be employed repeatedly for the enzymatic preparation of 6-ami...
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JPS5654150B2 |
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JPS5650839B2 |
h the bed, the process has the further advantage of utilizing standard process equipment.
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JPS5646840B2 |
6-Aminopenicillanic acid is prepared by enzymatic degradation of benzylpenicillin or of phenoxymethylpenicillin at pH 6.0-9.0 using a novel water-soluble enzyme complex derived from a penicillin deacylase enzyme bonded to a water-soluble...
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JPS5634280B2 |
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JPS5664796A |
PURPOSE: To prepare the titled compounds through the enzymic method readily in high yield, by bringing benzylpenicillin S-oxide into contact with an enzyme produced by a bacterium belonging to the genus Arthrobacter. CONSTITUTION: Benzyl...
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JPS5622518B1 |
A process for the enzymatic hydrolysing of diacyl-penicillins to semi-synthetic penicillins of the general formula:
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JPS5622278B1 |
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JPS5621396B2 |
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JPS5645196A |
PURPOSE: To prepare a β-lactam antibacterial agent continuously, in high efficiency, by reacting an ester having a specific structural formula with an aminoazetidinonecarboxylic acid having a specific structural formula in an aqueous so...
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JPS5629999A |
Isopenicillin derivatives having antimicrobial properties and a general formula of: where R, R1, and R2 are hydrogen, methyl, ethyl, propyl, isopropyl, or halogenated methyl, ethyl, propyl or isopropyl radicals and R3 is +TR are produced...
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JPS5549831B2 |
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): (I) In addition to being a broad spectrum antibiotic of medium potency, clavu...
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JPS5549830B2 |
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): (I) In addition to being a broad spectrum antibiotic of medium potency, clavu...
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JPS5549833B2 |
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): (I) In addition to being a broad spectrum antibiotic of medium potency, clavu...
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