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WO/2022/228505A1 |
Disclosed are a D-amino acid oxidase mutant and an application thereof in preparing L-glufosinate. When the D-amino acid oxidase mutant is compared with the amino acid sequence of a D-amino acid oxidase containing the sequence shown in S...
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WO/2022/227239A1 |
Provided are a strain of halophilic petroleum-hydrocarbon-degrading bacterium and the use thereof. The halophilic petroleum-hydrocarbon-degrading bacterium Halomonas elongate ZQ1-3 was deposited in the China General Microbiological Cultu...
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WO/2022/227413A1 |
Provided are a mutant protein of niacinamide phosphoribosyltransferase (NAMPT) having increased enzyme activity, a recombinant expression vector containing a nucleotide sequence encoding the mutant protein, a recombinant bacterium expres...
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WO/2022/231178A1 |
The present invention relates to a novel lactobacillus fermentum ATG-V5 strain or a composition for enhancing immunity, comprising same. The Lactobacillus fermentum ATG-V5 strain of the present invention has no cytotoxicity, and has the ...
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WO/2022/182908A9 |
Some embodiments include bacterial species for use in treatment of social behavioral deficit symptoms in a subject in need thereof. The bacterial species can include Enterococcus faecalis. Upon treatment, one or more symptoms of behavior...
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WO/2022/226376A2 |
This invention relates to compositions and methods for improving plant health, wherein a plant is heterologously disposed to one or more endophytes, or derived from a plant element heterologously disposed to one or more endophytes.
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WO/2022/223005A1 |
Provided is a method for promoting bone healing using Lactiplantibacillus plantarum TWK10 (CGMCC NO. 13008).
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WO/2022/222213A1 |
Provided is recombinant bacteria for producing β-elemene. Also provided are a method for constructing the recombinant bacteria and a method for producing β-elemene by using the recombinant bacteria. The recombinant bacteria express Sol...
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WO/2022/222591A1 |
Provided are a Lactobacillus paracasei strain for enhancing the therapeutic effect of an immune checkpoint inhibitor and the use thereof, wherein the strain has a deposit number of CCTCC NO: M 2020474. In addition, the strain can recruit...
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WO/2022/225257A1 |
The present invention relates to a Lactobacillus reuteri JH53 strain having excellent organic acid resistance and conversion of 1,3-propandiol from glycerol, and a use thereof. Since the strain of the present invention has better organic...
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WO/2022/223505A1 |
The present invention relates to controlling the amount of by-products resulting from N- terminal truncation of a polypeptide expressed in a host cell. In particular, the present invention relates to method of producing a recombinant pol...
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WO/2022/222392A1 |
A diatomite-loaded biogenic iron-manganese oxide material, a preparation method therefor, and an application thereof. The preparation method comprises: inoculating a strain into a culture medium containing divalent iron, divalent mangane...
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WO/2022/096573A9 |
The present invention relates to a composition for improvement of a skin condition comprising a supernatant produced from fermentation of a bacteria wherein the supernatant comprises at least 3 metabolites produced by the bacteria during...
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WO/2022/217705A1 |
Provided are a modified acid phosphatase and an application thereof. According to the mutant modified acid phosphatase PaAPasemu3, vitamin C is converted into vitamin C phosphate by expressing the modified acid phosphatase PaAPasemu3 in ...
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WO/2022/218325A1 |
The present invention belongs to the technical field of biological vaccine products. Disclosed are a gene-deleted attenuated African swine fever virus strain, and a construction method therefor and the use thereof. In the present inventi...
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WO/2022/116815A9 |
Provided are a stable lentivirus packaging cell line and a preparation method therefor. The stable lentivirus packaging cell line contains a packaging plasmid group consisting of a pPuro.coTetR plasmid, a pVSVG plasmid, and a pGagPol-RRE...
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WO/2022/218335A1 |
The present invention relates to a Lactobacillus reuteri, and a use, composition, drug and food thereof. The present Lactobacillus reuteri has the preservation number of CGMCC No. 21577, can improve intestinal flora disorder, reduce inte...
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WO/2022/213898A1 |
Provided are an Oscillospiraceae strain LBM10036, which has a deposit number of GDMCC No: 61202, and the use thereof. The strain has a capacity to utilize various substrates, can efficiently synthesize caproic acid under the condition of...
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WO/2022/213518A1 |
An array microfluidic chip (100) and a method for operating an antibiotic susceptibility test. The array microfluidic chip (100) comprises a chip body (110), a transparent hydrophilic film (120), and a cover sheet (130); the chip body (1...
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WO/2022/214700A1 |
A strain of Lacticaseibacillus paracasei EM025-11 is described. The strain has an unusually broad catabolic activity including for prebiotics not normally utilized by commensal lactobacilli and is therefore suitable for inclusion in a sy...
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WO/2022/216678A1 |
Maize is vital to both US agriculture and the economy. The US provides over half of the maize global market. In the US, field maize production is a $75B endeavor and comprises 95% of the total US grain production. Worldwide there is a ne...
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WO/2022/213660A1 |
Disclosed in the present invention are recombinant Escherichia coli for producing heparosan and the use thereof, belonging to the technical field of bioengineering. By means of the present invention, pathway genes glmS, glmM, glmU, galU ...
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WO/2022/213700A1 |
Provided in the present invention is a strain of Lactobacillus having a memory-enhancing capacity, which can be used for preparing functional foods, health care products and drugs for improving the memory capacity of healthy individuals ...
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WO/2022/216088A1 |
The present application relates to: an L-arginine-producing microorganism in which a protein containing an amino acid sequence of SEQ ID NO: 1 is attenuated; and an L-arginine production method using the microorganism.
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WO/2022/216731A1 |
Provided are modified bacteria and methods of using the modified bacteria for prophylaxis or treatment of bacterial infections. The modified bacteria contain one or more genomic modifications such that the genomes of the bacteria are alt...
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WO/2022/213507A1 |
Provided are Christensenellaceae, and a composition and a pharmaceutical use thereof. The Christensenellaceae can be used for treating or preventing liver function damage and related diseases, digestive tract mucosa damage and related di...
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WO/2022/211674A1 |
The invention relates to biotechnology. The invention relates to biotechnology. Proposed is a method of cultivating aerobic methane-assimilating Methylococcus capsulatus microorganisms in a continuous flow mode with a constant rate of cu...
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WO/2022/208531A1 |
The present invention relates to a novel primers and rapid loop mediated isothermal amplification method for detection of Corynebacterium diphtheriae. Further, the present invention also provides an assay for differentiating between toxi...
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WO/2022/211551A1 |
The present invention relates to novel microbes with plastic decomposition activity and a use thereof. The present invention newly discovered Pseudomonas lini) JUN 01 and Acinetobacter johnsonii JUN 01, which are strains with ability to ...
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WO/2022/206300A1 |
Provided is a composition capable of facilitating defecation, comprising: lactic acid bacteria fermented powder containing a lactic acid bacteria fermented substance, the lactic acid bacteria fermented substance being obtained by culturi...
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WO/2022/211587A1 |
The present invention relates to a novel Sphingomonas paucimobilis strain. The present invention also relates to use of the Sphingomonas paucimobilis strain. Particularly, the present invention relates to a method or composition for skin...
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WO/2022/210308A1 |
The present invention addresses the problem of improving the productivity of a cyclic lipopeptide such as Surfactin by microbial culture. The present invention provides: a cyclic lipopeptide-producing microbial strain that lacks a gene...
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WO/2022/211562A1 |
The present invention relates to a novel recombinant microalgal strain having enhanced resistance to high concentrations of CO2 and low pH (acidic) conditions and, more particularly, to Chlamydomonas reinhardtii PMA4ΔCter-V4 and -V10, w...
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WO/2022/211736A1 |
Disclosed herein is a lipase variant comprising a first substituent of a lipase sequence of SEQ ID No. 2, wherein a position of the first substituent in SEQ ID No. 2 is selected from the group consisting of position 251, position 204, po...
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WO/2022/206232A1 |
A fermented apple cider containing Chinese privet and a preparation method therefor. The method comprises the following steps: coring apples, then beating and crushing the apples, adding a sulfurous acid solution while crushing, and filt...
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WO/2022/209658A1 |
The present invention addresses the problem of providing a new enzyme that specifically hydrolyzes an α-1,2-glucoside bond, and a production method therefor. The above problem is solved by providing an α-1,2-glucosidase which has activ...
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WO/2022/199460A1 |
Disclosed are an aspartate kinase gene expression regulatory sequence and the use thereof. By modifying positions 366-373 of a sequence represented by SEQ ID NO: 1, a polynucleotide formed by linking the sequence with a start codon GTG o...
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WO/2022/198846A1 |
Provided are a microorganism for producing a pantoic acid, and a construction method therefor and an application thereof. The microorganism for producing the pantoic acid is obtained by knocking out a gene in Escherichia coli and introdu...
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WO/2022/203117A1 |
The present invention relates to an oncolytic virus for treating brain tumors by using a Newcastle disease virus vector-based recombinant Newcastle disease virus (NDV) into which a phosphatase and tensin homolog (PTEN) gene is inserted, ...
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WO/2022/198990A1 |
A method for increasing the yield of eicosapentaenoic acid in Schizochytrium sp., the method comprising: inoculating Schizochytrium sp. ATCC 20888 into a fermentation culture medium, fermenting same under an aerobic condition, changing t...
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WO/2022/200851A1 |
Disclosed herein is an isolated strain of Lactobacillus delbrueckii subsp. lactis LDL557, which is deposited at Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH under an accession number DSM 33617. Also disclosed herein are a ...
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WO/2022/199660A1 |
Disclosed are Lactobacillus rhamnosus having the accession number of CCTCC NO: M 2021185, a ferment lysate prepared thereby for regulating skin microecology, and a preparation method for the lysate ferment. The ferment lysate comprises t...
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WO/2022/198278A1 |
The present invention provides a hydrogel buoyant bead comprising cross-linked carbonic anhydrase, wherein the (hydrated) bead has a density of less than 1.03 g/cm3 (at 20°C). In one embodiment, the bead is a glutaraldehyde crosslinked ...
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WO/2022/201197A1 |
The present invention provides a mutant yeast strain that is capable of alcohol fermentation, preferably high gravity fermentation (HGF) or very high gravity fermentation (VHGF). Particularly, the mutant yeast strain is of Meyerozyma car...
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WO/2022/203008A1 |
Disclosed is a method for identifying bacteria that cause sepsis, wherein the method includes: a step for performing PCR using a sample collected from a subject and a combination of sets of primers each specific to the full length or a p...
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WO/2022/203302A1 |
The present invention relates to a novel strain of Lactobacillus fermentum having an excellent effect of preventing or ameliorating an oral disease and use thereof. More specifically, the present invention relates to a strain of Lactobac...
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WO/2022/194189A1 |
Provided in the present invention is a Lactobacillus Bangia fusco-purpurea fermentation supernatant having an α-glucosidase inhibitory activity. The method for preparing the Lactobacillus Bangia fusco-purpurea fermentation supernatant c...
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WO/2022/197241A1 |
The present invention relates to a Bacillus subtilis strain isolate DSM33646 which is capable of propagating and secreting mannolytic enzymes to hydrolyse at least three forms of mannan polymers upon contact with solvent- extracted palm ...
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WO/2022/195075A1 |
The present invention relates to the identification of a novel isolated lactic acid bacterial species. More specifically, a novel Latilactobacillus species, Latilactobacillus fragifolii sp. nov., with the type strain AMBP162T is proposed...
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WO/2022/193398A1 |
Provided are a trivalent dimethylarsinous acid induced human keratinocyte malignant transformation cell strain, and the use thereof, which belong to the technical field of model construction. An inorganic arsenic metabolite trivalent dim...
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