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WO/2023/207909A1 |
Disclosed is a CRISPR-based detection kit and use thereof. The detection kit of the present invention comprises a gene editing system. The gene editing system comprises a nuclease and a guide RNA. The sequence of the guide RNA is selecte...
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WO/2023/202353A1 |
The present invention belongs to the technical field of microorganisms. Disclosed is a bifidobacterium longum CCFM1206 strain for producing sulforaphane and capable of relieving inflammation. The bifidobacterium longum CCFM1206 provided ...
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WO/2023/025936A9 |
The present invention is in the field of microbiology. The present application provides novel lactobacilli with inactivated regulatory sequences for manganese transporter MntH1 as well as composition comprising the bacteria. Such bacteri...
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WO/2023/202027A1 |
Disclosed in the invention is a vaginal microecological detection primer-probe combination and a kit. The primer-probe combination comprises primers and probes for detection of target genes of lactobacillus crispatus (LC), lactobacillus ...
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WO/2023/202608A1 |
The present application relates to the technical field of biology, in particular to a beauveria bassiana strain with high ultraviolet radiation resistance as well as a directional mutagenesis method therefor and use thereof. The beauveri...
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WO/2023/203011A1 |
The invention relates to preparation of plant-based meat analogue products with Leuconostoc carnosum. Such products can be made by inoculating a composition comprising said bacteria on plant based starting material. The invention also pr...
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WO/2023/205763A1 |
The present invention relates, at least in part, to the production of resveratrol from 4-coumaric acid. The production can be mediated in a transgenic Saccharomyces cell.
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WO/2023/202122A1 |
Provided are a Curcuma wenyujin Y. H. Chen & C. Ling-derived curcumin synthetase, a gene, a vector, an engineered bacterium, and use thereof. The amino acid sequence of the curcumin synthetase is set forth in SEQ. ID NO. 2. The sequence ...
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WO/2023/201809A1 |
Provided are a transaminase mutant and use thereof, wherein the transaminase mutant is obtained by mutation of an amino acid sequence set forth in SEQ ID NO: 1, the mutation at least comprising: T291A; or the amino acid sequence of the t...
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WO/2023/204396A1 |
The present invention relates to high-protein microalgal biomass having excellent pepsin digestibility, a culture method and use thereof. A composition disclosed in the present invention has a high protein content, but also contains omeg...
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WO/2023/200203A1 |
The present invention relates to a novel Lactobacillus rhamnosus KBL2290 strain and a composition comprising same, wherein the strain shows various activities such as improving intestinal flora, anti-inflammation, and strengthening intes...
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WO/2023/197093A1 |
Provided are preparation method and use of physical stimulation to control lysis and intracellular substance release of bacteria capable of producing bacterial cellulose. Provided is a plasmid for physically controlling bacterial lysis, ...
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WO/2023/197743A1 |
Provided is a method for improving an ability of a Bacillus species to remove red tide algae cells. Specifically, the method comprises: co-culturing the Bacillus species and a clay to improve the biomass and algae removal ability of the ...
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WO/2023/201078A1 |
The present invention provides for a genetically modified host cell comprising a first polypeptide capable of active transport of urea into the host cell and/or a second polypeptide capable of degrading urea into ammonia and carbon dioxi...
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WO/2023/198856A1 |
The invention relates to a method for producing proteins comprising the following steps: providing a culture medium containing at least one material fraction from the production of beer or another drink based on gluten-containing grain; ...
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WO/2023/197692A1 |
The present invention provides an engineered strain of yeast having mitochondrion-positioned reductive TCA pathway and efficiently producing succinic acid, a construction method therefor and use thereof, and belongs to the technical fiel...
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WO/2023/197365A1 |
The present invention relates to the technical field of fusion proteins. Provided are a recombinant protein carrying a target protein and autonomously entering a eukaryotic cell, a recombinant expression vector, a recombinant bacterium, ...
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WO/2023/197968A1 |
The present invention relates to the technical field of genetic engineering and fermentation engineering, and particularly, to a method for preparing isopropanolamine. The method is characterized in that threonine is converted into L-2-a...
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WO/2023/201326A1 |
The present disclosure is directed to compositions and methods for effectively liberating bioactive compounds from fibers for significant host physiological and metabolic benefit.
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WO/2023/201346A1 |
Methods of growing biomass from filamentous fungi using two or more culture steps are described. The biomass produced by the methods described has a dispersed hyphal morphology and/or increased protein content. The filamentous fungi used...
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WO/2023/197536A1 |
The present application provides a peanut meal production method using bacillus velezensis and pediococcus acidilactici for stepwise fermentation, which relates to the technical field of biology and mainly aims to provide a fermentation ...
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WO/2023/199004A1 |
The present invention relates to a Saccharomyces cerevisiae yeast obtained by culturing the Saccharomyces cerevisiae strain deposited on 3 March 2021 at the CNCM under number I-5660, which is an active yeast strain having the following c...
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WO/2023/193353A1 |
Provided are an engineered microorganism expressing an acetoacetyl coenzyme A reductase variant and a method for increasing the PHA yield. Compared with the wild-type acetoacetyl coenzyme A reductase set forth in SEQ ID NO. 31, the varia...
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WO/2023/193124A1 |
The present invention discloses a coated concentrated composition which allows the controlled release of an extract rich in saponins and polyphenols, which is used for controlling gastrointestinal diseases in birds and improving producti...
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WO/2023/193837A1 |
The present invention provides a novel expression vector (plasmid) containing a newly designed ORI sequence. The novel expression vector is more stable and provides for a high production of recombinant protein per total biomass.
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WO/2023/193722A1 |
The present invention relates to an echinocandin compound, and a preparation method therefor and the use thereof. Specifically, disclosed in the present invention are an echinocandin B deoxidation analogue and a biosynthesis method there...
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WO/2023/184631A1 |
An Akkermansia muciniphila, with an accession number of CGMCC No. 23185. Use of the Akkermansia muciniphila in preparing a drug for preventing and/or treating a pancreatic tumor. A composition, comprising the Akkermansia muciniphila as a...
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WO/2023/191365A1 |
The present invention relates to: a novel Irpex lacteus strain having the excellent effects of controlling anthracnose in plants, phytophthora bright, fusarium wilt, gray mold, lettuce sclerotinia rot, sclerotinia rot on basil, white rot...
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WO/2023/185569A1 |
Lactobacillus pentosus CCFM1227 capable of relieving pathological features of mice infected with influenza viruses and the use of same in preparation of related products. A product prepared by means of the Lactobacillus pentosus CCFM1227...
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WO/2023/186037A1 |
Provided is a method for preparing glycine by using threonine. In a fermentation process, threonine is decomposed into glycine and acetaldehyde by aldolase. Also provided is a method for simultaneously preparing glycine and acetyl coenzy...
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WO/2023/191073A1 |
To isolate a novel bacteriophage exhibiting bacteriolytic activity specific to bacteria of the genus Xanthomonas in order to control plant diseases caused by Xanthomonas bacteria, and to develop and provide a plant disease control compos...
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WO/2023/185443A1 |
Disclosed are an intelligent and controllable microbial drug factory and use thereof in skin wound healing, said microbial drug factory comprising a gene expression loop control system and a chassis probiotic. Also disclosed are a glucos...
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WO/2023/185760A1 |
The present invention provides a butyric acid-producing probiotic, a method for constructing same, and use thereof. The probiotic can improve symptoms of ulcerative colitis, depression, obesity, and fatty liver disease. The probiotic has...
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WO/2023/191074A1 |
To control plant diseases caused by Xanthomonas spp., a novel bacteriophage exhibiting bacteriolysis activity specifically on Xanthomonas spp. was isolated. Thus, developed and provided is a plant disease control composition containing t...
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WO/2023/191071A1 |
According to the present invention, in order to prevent plant disease caused by bacteria of the genus Xanthomonas, a novel bacteriophage that exhibits bacteriolytic activity specific to bacteria of the genus Xanthomonas is isolated, and ...
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WO/2023/191263A1 |
The present application relates to: a microorganism with attenuated SIRT-type deacetylase protein activity; a method for producing O-acetyl homoserine and L-methionine using same; a composition for producing O-acetyl homoserine comprisin...
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WO/2023/187100A1 |
The invention relates to the field of fungal production of dyes and pigments and applying said fungal production of dyes for dyeing substrates. More specifically, the invention relates to an isolated fungus belonging to the species Fusar...
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WO/2023/187753A1 |
Heterologous polypeptides expressed in a recombinant eukaryotic host cell may exhibit reduced stability and/or biological activity when expressed in an intracellular form. The present disclosure provides a heterologous polypeptide compri...
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WO/2023/185918A1 |
Provided is an E. coli expressed recombinant human microplasmin (E-μPlm), a production method thereof, a pharmaceutical composition and a kit comprising thereof, an application of the pharmaceutical composition and the kit in treating t...
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WO/2023/191196A1 |
The present invention relates to a composition for reducing skin photoaging, comprising Pediococcus acidilactici LM1013 (KCTC12039BP) as an active ingredient. The composition for reducing skin photoaging, comprising Pediococcus acidilact...
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WO/2023/191072A1 |
In order to control plant diseases caused by genus Xanthomonas bacteria, the present invention isolates a novel bacteriophage that demonstrates lytic activities specifically against the bacteria, and develops and provides a plant disease...
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WO/2023/184724A1 |
Disclosed in the present invention are an antimycin compound as well as a preparation method therefor and the use thereof. The compound is characterized in that the compound is separated from a secondary metabolite of marine actinomycete...
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WO/2023/191490A1 |
The present application relates to: a composition for enhancing plant disease resistance, the composition containing a Bacillus amyloliquefaciens microorganism and/or a culture thereof, deposited under accession number KCCM13138P; a comp...
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WO/2023/180525A1 |
Provided is a thermo-regulated process for the recombinant production of an Fc-peptide fusion protein in prokaryotic host cells comprising a single mild temperature shift in the induction phase.
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WO/2023/182583A1 |
The present application relates to: a yarrowia microorganism having the ability to produce carotenoid, or a material having carotenoid as a precursor, the microorganism expressing Geranylgeranyl pyrophosphate synthase that is derived fro...
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WO/2023/182584A1 |
The present application relates to: a method for producing retinol, comprising a step of culturing a microorganism of the genus Yarrowia in a medium containing a nonionic surfactant; a method for increasing retinol production; a method f...
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WO/2023/178374A1 |
An isolated nucleic acid associated with increased accumulation of astaxanthin derived from a Xanthophyllomyces dendrorhous strain. The isolated nucleic acid comprising nucleotide sequence set forth in SEQ ID NOs: 1240-12684 or a nucleot...
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WO/2023/182581A1 |
The present application relates to: a method for producing retinol, comprising a step of culturing a Yarrowia sp. microorganism in a medium comprising an anti-oxidant; a method for increasing the production of retinol; a method for produ...
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WO/2023/178849A1 |
The present invention relates to the field of biotechnology. Provided is an Escherichia coli strain for synthesizing L-valine, a method for constructing same, and use thereof. Provided is an Escherichia coli strain named as Escherichia c...
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WO/2023/182582A1 |
The present application relates to: a yarrowia microorganism having the ability to produce carotenoid, or a material having carotenoid as a precursor, the microorganism expressing Geranylgeranyl pyrophosphate synthase that is derived fro...
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