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Matches 251 - 300 out of 54,843

Document Document Title
WO/2023/173899A1
Provided are Bacillus coagulans for ameliorating constipation and an application thereof. The strain is preserved in China General Microbiological Culture Collection Center on 10 November 2021, and has a preservation number of CGMCC No.2...  
WO/2023/174959A1
The present invention relates to a process for clarifying a liquid obtained from a plant material, wherein said process involves the use of laccase and fungal p- glucans.  
WO/2023/177253A1
The present application provides: a variant polypeptide having an activity of aspartate 1-dicarboxylase; a microorganism including same; a composition for producing beta-alanine or beta-alanine-derived compounds, the composition comprisi...  
WO/2023/177254A1
The present application provides: a microorganism with enhanced activity of aspartate 1-decarboxylase derived from Tribolium castaneum; a composition for producing beta-alanine and/or a beta-alanine-derived compound, the composition comp...  
WO/2023/175351A1
The present invention relates to the genetic engineering of biotin-expressing cells, and to the enzyme engineering of biotin synthase (bioB), to enhance D-biotin biosynthesis. The invention also provides optimised methods of culturing th...  
WO/2023/177215A1
Provided are a Weissella cibaria strain having dental health enhancement activity and use thereof.  
WO/2023/177218A1
A Lacticaseibacillus paracasei strain having periodontal pathogen inhibitory activity, and use thereof are provided.  
WO/2023/177208A1
The present invention relates to a method for preparing lactic acid bacterium-derived extracellular vesicles with improved yield. The inventors of the present invention have identified the optimal medium composition and fermentation cond...  
WO/2023/173735A1
The present invention relates to the field of water-retaining materials, and in particular, to a biological water-retaining material, and a preparation method therefor and the use thereof. In order to solve the problem in the prior art o...  
WO/2023/173566A1
The present invention relates to saccharomyces cerevisiae for producing rubusoside and an application thereof. A rubusoside synthesis gene is expressed in a saccharomyces cerevisiae strain, and an ABC efflux pump is overexpressed; and th...  
WO/2023/175620A1
The present disclosure provides marine-derived bacterium, consortium comprising the same and uses therefore for hydrolyzing carbohydrate.  
WO/2023/175079A1
The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The present invention relates to newly identified alpha-2, 6-sialyltransferases having alpha- 2,6-sialyltransferase activit...  
WO/2023/173637A1
The present invention provides a Bifidobacterium animalis subsp. lactis strain BLa36 for relieving constipation, a method for culturing same, and use thereof. The Bifidobacterium animalis subsp. lactis strain BLa36 for relieving constipa...  
WO/2023/142861A9
The present invention provides a method for constructing a threonine-producing engineered bacterium. According to the present invention, a 2-formyl-citrate synthase 1-inactivated strain (corynebacterium) is applied to the production of t...  
WO/2023/173565A1
Provided is a method for simultaneously enhancing and inhibiting multiple key genes during synthesis of 7-dehydrocholesterol in Saccharomyces cerevisiae by means of a dCpf1-VP activation system and a dCas9-RD inhibition system. In order ...  
WO/2023/170280A1
The invention relates to the expression and secretion of transforming growth factor beta (TGFβ) in methylotrophic yeast such as Pichia pastoris (P. pastoris), yeast cells whose genome comprises TGFβ, and uses thereof, including use in ...  
WO/2023/169200A1
Provided are a recombinant yeast for producing lacto-N-triose, and an application thereof. The recombinant yeast comprises an amino acid sequence of a β-N-acetylglucosaminyl transferase and a coding nucleic acid sequence thereof, and/or...  
WO/2023/169393A1
A method for preparing a fermented milk with live bacteria at normal temperature. The method comprises the following steps: fermenting a fermentation base material with lactose-negative bacteria other than Lactobacillus rhamnosus as ferm...  
WO/2023/169184A1
Provided are engineered transaminase polypeptides for the synthesis of Ubrogepant intermediates with high stereoselectivity, high catalytic activity and good stability. Also provided is a reaction process for the asymmetric synthesis of ...  
WO/2023/171643A1
[Problem] To provide a ketose 3-epimerase or a protein having the same activity in a mode in which an effect thereof can be maintained over a long period of time even under severe preservation conditions. [Solution] A dried body of an im...  
WO/2023/165521A1
An engineered microorganism, which comprises one or more of a gene encoding an aromatic amino acid transaminase, a gene encoding phenylalanine dehydrogenase, a gene encoding phenylpyruvate decarboxylase, a gene encoding an aldehyde reduc...  
WO/2023/168315A1
A process for producing styrene converts Z-phenylalanine using a first biocatalyst comprising a PAL enzyme (phenylalanine ammonia lyase from Rhodorotula glutinis EC 4.3.1.24) and a second biocatalyst comprising a Fdc1 enzyme (ferulic aci...  
WO/2023/165607A1
Provided is a strain of high organic zinc enrichment Bifidobacterium animalis for promoting growth and reproductive development, which belongs to the technical field of microorganisms. The Bifidobacterium animalis CCFM1230 obtained by me...  
WO/2023/166455A2
The present invention relates to a method for producing an extract obtained by fungal fermentation and the various applications of such an extract.  
WO/2023/164985A1
A genetically engineered bacterium for synthesizing p-coumaric acid and derivatives thereof, a method for constructing same and use thereof. The genetically engineered bacterium for synthesizing p-coumaric acid comprises a chassis strain...  
WO/2023/159745A1
The present application relates to the technical field of bioengineering, and provides a genetically engineered bacterium for co-production of 3-hydroxypropionic acid and 1,3-propanediol, and a construction method therefor and an applica...  
WO/2023/159572A1
Provided in the present invention are a detection kit, primer composition and detection method for novel coronavirus SARS-CoV-2. The detection kit for novel coronavirus SARS-CoV-2 comprises a first primer set for an Orflab gene of novel ...  
WO/2023/159787A1
Provided are a BCG recombinant strain ΔBCG_1820 in which BCG_1820 gene is knocked out, a preparation method therefor, and the use thereof in preparing a tuberculosis vaccine. The BCG recombinant strain ΔBCG_1820 can induce macrophages ...  
WO/2023/159960A1
Provided are probiotic lactobacillus plantarum CMRC 19L and an application thereof in the preparation of a low-salt fermented meat food product. The lactobacillus plantarum CMRC 19L has been deposited in the China General Microbiological...  
WO/2023/157641A1
The purpose of the present invention is to provide a lipid production control factor for yeast. Yeast gene 110315 serves as a lipid production control factor.  
WO/2023/155474A1
Disclosed are a meso-2,3-butanediol dehydrogenase and a mutant and use thereof. The meso-2,3-butanediol dehydrogenase has an amino acid sequence set forth in SEQ ID NO: 1. According to the present invention, a meso-2,3-butanediol dehydro...  
WO/2023/155864A1
Provided are a caffeic acid O-methyltransferase (COMT) mutant and use thereof. A site in an amino acid sequence of COMT closely related to the catalytic activity of COMT thereof is found, and on this basis, a COMT mutant and use thereof ...  
WO/2023/157016A1
The present disclosure provides an isolated strain of Amycolatopsis sp. WGS_07 having accession number MCC 0218. The present disclosure provides a process for synthesizing furano-naphthoquinone and pyrazinone derivatives using a novel st...  
WO/2023/155568A1
Provided are Lactobacillus paracasei L511 with an inhibitory effect on the growth of a liver cancer tumor and use thereof. The strain has been deposited in China General Microbiological Culture Collection Center on January 14, 2022, unde...  
WO/2023/151407A1
Provided in the present invention is a construction method for a threonine-producing strain. The present invention performs superimposed modification on a plurality of enzymes related to threonine synthesis and redox capacity supplement,...  
WO/2023/154805A2
The present disclosure provides water-soluble film packages composed of a water-soluble film, where the packages include: one or more compartment(s) including dehydrated microbes. The disclosure further provides methods of production of ...  
WO/2023/151556A1
Provided are an engineering probiotic for degrading uric acid, and a construction method therefor and the use thereof, which belongs to the field of biotechnology. The probiotic Escherichia coli Nissle 1917 is used as an original startin...  
WO/2023/151411A1
The present invention relates to the technical field of microbial engineering, in particular to a recombinant microorganism for producing threonine, and a construction method therefor and the use thereof. In the present invention, an ace...  
WO/2023/151406A1
Provided in the present invention is a method for constructing a threonine-producing strain. By means of performing overlay modification on a plurality of enzymes related to the synthesis of threonine, including aspartate aminotransferas...  
WO/2023/151409A1
The present invention provides a method for constructing high-yield engineered bacteria for threonine. According to the present invention, strains of which the activities of aspartate aminotransferase, aspartokinase, homoserine dehydroge...  
WO/2023/151408A1
Provided in the present invention is a construction method for a strain with high-yield production of threonine. In the present invention, the expression of one or more of aspartate aminotransferase, aspartokinase and threonine synthase ...  
WO/2023/152413A1
The present invention relates to a methodology for modifying the expression and production of volatile organic compounds from fungi, entomopathogenic fungi, nematophagous fungi and/or endophytes which exhibit resistance to chitosan, by t...  
WO/2023/151346A1
The present invention provides construction and application of a novel bispecific chimeric antigen receptor (CAR), and relates to the technical field of immunotherapy. The CAR provided by the present invention comprises an antigen-bindin...  
WO/2023/148301A1
The present invention relates to modified microbial host cells, the modification modulates protease activity of at least one endogenous protease if compared with a parent microbial host cell which lacks the modification and measured unde...  
WO/2023/150533A1
Disclosed are modified microorganisms (e.g., bacteria) capable of producing MK-7, andmethods of producing MK-7 using such modified microorganisms.  
WO/2023/142881A1
Provided in the present invention is a method for constructing a threonine-producing strain. In the present invention, using a pyruvate quinone dehydrogenase-inactivated strain (Corynebacterium) in the production of threonine can increas...  
WO/2023/142285A1
Provided are an attenuation method for influenza viruses, an attenuated influenza virus strain, and the use. The attenuation method comprises: deleting bases of an arbitrary number at random positions on an influenza virus conserved regi...  
WO/2023/142855A1
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a recombinant microorganism, a method for constructing same and use thereof. According to the present invention, by means of constr...  
WO/2023/142872A1
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of corynebacterium genus producing threonine, a method for constructing the same, and use thereof. The act...  
WO/2023/142854A1
Provided is a method for constructing a threonine production strain. By means of constructing a corynebacterium having an enhanced transketolase activity, the threonine production capacity of the strain is improved. In combination with e...  

Matches 251 - 300 out of 54,843