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Matches 301 - 350 out of 54,843

Document Document Title
WO/2023/142499A1
The present invention belongs to the field of genetic engineering and grain science. Disclosed is the use of Aspergillus cristatus glucose oxidase in improving the processing quality of flour. In the present invention, recombinant Asperg...  
WO/2023/142162A1
Disclosed are a bacillus strain WYJ-E14 isolated from curcuma wenyujin Y. H. Chen & C. Ling and use thereof in the preparation of an anti-tumor drug. An endophyte isolated from a rhizome part of curcuma wenyujin Y. H. Chen & C. Ling belo...  
WO/2023/146387A1
The present invention relates to an unregulated Δnrg1 FMA2 U. maydis mutant strain in nrg1 metabolism for producing MEL and UA in the presence of nitrogen. It describes the production of a mixture of glycolipids from the culture of the ...  
WO/2023/142201A1
A method for the industrial production of a vaccine against Pseudomonas aeruginosa. By using a series of standardized, programmed and digital settings, it is ensured that a vaccine with stable quality containing whole Pseudomonas aerugin...  
WO/2023/142040A1
An HSV vector with ICP27 under control of CXCR4 promoter and miRNA-223/125b and ICP34.5 under control of miRNA-124/143, and deletion of one RL and one RS region of the viral genome. Within optional embodiments the mutation is a deletion ...  
WO/2023/143495A1
An HSV vector with ICP27 under control of CXCR4 promoter and miRNA-223/125b and ICP34.5 under control of miRNA-124/143, and deletion of one RL and one RS region of the viral genome. Within optional embodiments the mutation is a deletion ...  
WO/2023/142871A1
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of the corynebacterium genus, a method for constructing same and use thereof. The activity of oxaloacetate...  
WO/2023/147487A1
The present disclosure relates generally to high-frequency ultrasonicator devices, and more specifically to high-frequency ultrasonicator devices for disrupting or lysing cells, and methods for using those devices.  
WO/2023/143136A1
Disclosed are a yeast engineering bacterium for fermentative production of α-santalene and use thereof. Yeast is used as an original strain, and by means of the introduction of a gene construct, a yeast engineering bacterium that can ef...  
WO/2023/142879A1
The present invention belongs to the field of microbial strains. Disclosed is use of bacillus coagulans in the preparation of a medicament or a food product for mitigating a decline of body functions caused by hyperglycemia and hyperlipi...  
WO/2023/144707A1
The present disclosure provides a method for increasing production of a polyunsaturated fatty acid, especially eicosapentaenoic acid (EPA), in a microorganism, comprising adjusting the macro- and/or micronutrients during fermentation. Th...  
WO/2023/144174A1
The invention provides Streptococcus thermophilus mutants, such as DSM22933, which have improved texturizing properties. The strains have: (i) a mutation in the branched chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) ...  
WO/2023/142848A1
Provided is a promoter, which has a nucleotide sequence shown in SEQ ID NO.1. The promoter is obtained by means of rationally designing a promoter of a dapA gene, has obviously reduced transcriptional activity and can be used for the wea...  
WO/2023/143063A1
Disclosed are a method for improving production of an adeno-associated virus by a baculovirus system, and an application. A recombinant baculovirus vector comprises an AAV capsid protein gene expression cassette (Cap), an AAV Rep gene ex...  
WO/2023/143023A1
The present application relates to the technical field of biomedicine, and specifically discloses an oncolytic virus and the use thereof. The oncolytic virus comprises an M protein, and the M protein contains amino acid substitutions at ...  
WO/2023/142877A1
Provided is the use of Bacteroides fragilis in the improvement and/or treatment of diarrhea. Tests of different mouse diarrhea models prove that Bacteroides fragilis ZY-312 with the deposit number of CGMCC No.10685 or inactivated Bactero...  
WO/2023/142860A1
The present invention provides a method for constructing a threonine-producing genetically engineered bacterium. According to the present invention, by means of reducing the activity of 2-formyl-citrate synthase 2 or inactivating the syn...  
WO/2023/142859A1
The present invention relates to the technical field of microbial engineering, and in particular to a modified Corynebacterium microorganism, a method for constructing same and use thereof. The present invention provides use of weakening...  
WO/2023/142873A1
The present invention relates to the technical field of microbial engineering. Specifically disclosed are a modified microorganism of corynebacterium genus, use thereof in producing threonine, and a method for constructing the same. The ...  
WO/2023/142862A1
Provided are a recombinant microorganism for producing threonine and the use thereof in the fermentation production of threonine or a derivative thereof. A 20-30 bp fragment upstream of an initiation codon of a gene encoding phosphoenolp...  
WO/2023/142853A1
Provided is a method for constructing a genetically engineered bacterium for highly producing threonine. The ability of the strain to produce threonine is improved by means of reducing the activity of the transcriptional regulation facto...  
WO/2023/142286A1
Provided are a group of attenuated strains of the influenza A virus based on synonymous mutation and/or deletion mutation, and a preparation method therefor and the use thereof. The attenuated strains are obtained by modifying an M2 gene...  
WO/2023/138266A1
Provided are a biomarker related to Parkinson's disease (PD) and an application thereof. Specifically, fungi, in particular Saccharomyces cerevisiae, can be used as a biomarker for PD diagnosis. Also provided is a detection method for fu...  
WO/2023/137785A1
An application of sativene, a recombinant biocontrol fungus, and bombyx batryticatus and an application thereof. Provided is an application of sativene in insect attraction and/or pest control. Sativene is attractive to insects. The high...  
WO/2023/138301A1
Provided are a surfactin synthase mutant and the use thereof. The surfactin synthase mutant or fragment thereof comprises an amino acid mutation located in a first functional domain of a first module of the surfactin synthase and on a bi...  
WO/2023/138678A1
Provided are Bacillus velezensis, and a composition, a plant growth promoter, a biological culture, and a plant growth substrate comprising Bacillus velezensis, and the present invention further relates to the use thereof. Specifically, ...  
WO/2023/138679A1
Provided is a method for synthesizing a flavonoid compound. The method comprises providing a recombinant prokaryotic cell, wherein, in the prokaryotic cell, the transmembrane protein rhodanese Ygap of Escherichia coli is up-regulated or ...  
WO/2023/137794A1
Disclosed in the present invention is a rapid detection system for novel coronavirus Omicron mutant strain typing. Primer probes in the system are designed on the basis of a bidirectional ARMS PCR technology, six mutation sites of a targ...  
WO/2023/134104A1
Provided is a method for improving the efficiency of integrated bioprocessing by means of using artificial microorganisms, which relates to the technical field of microorganisms. The method comprises the following steps: mixing a plurali...  
WO/2023/134205A1
Provided are a drug containing Bacteroides fragilis, in particular to Bacteroides fragilis ZY-312 having a deposit number of CGMCC No.10685, and a PD-1 antibody and/or a PD-L1 antibody, and a use of the drug in correcting an immune cell ...  
WO/2023/134446A1
The present disclosure belongs to the field of synthetic biology and relates to a valencene synthase mutant and a valencene high-yield strain. An enzyme for synthesizing valencene is derived from Eryngium glaciale, and upon enzyme direct...  
WO/2023/135607A1
The present invention provides a method for preparation of functional curd with anti-ageing property and high shelf life. It comprises collecting fresh cow milk from a dairy farm aseptically in a sterilized bag and maintaining refrigerat...  
WO/2023/135390A1
The present invention relates to a method for determining the methicillin-resistance properties of a Staphylococcus aureus strain present in a biological sample, the method comprising the following steps: • a) incubating the biological...  
WO/2023/134365A1
A use of five compounds or a lactobacillus in the preparation of a composition for regulating lipid absorption or body weight, comprising: (a) a compound combination being a combination of DL-3-phenyllactic acid, 4-hydroxyphenyllactic ac...  
WO/2023/134204A1
Disclosed is an application of zwitterionic capsular polysaccharide of Bacteroides fragilis combined with a PD-1 antibody and/or a PD-L1 antibody in the prevention and treatment of respiratory system tumors. According to the present inve...  
WO/2023/133484A1
Aspects of the disclosure relate to modified skin commensal bacterial host cells capable of producing anthranilate or derivatives thereof.  
WO/2023/131588A1
The present invention relates to a liquid culture medium comprising yeast extract, glycine, arginine, glutamine, serine, threonine, magnesium ions, calcium ions, selenium and water. It further relates to a liquid feed composition for use...  
WO/2023/132628A1
The present invention relates to a novel microorganism, a lysate thereof, a culture broth thereof, an extract of the culture broth, vesicles therefrom, and anti-inflammatory and/or antibacterial uses thereof. A novel strain and vesicles ...  
WO/2023/131173A1
Provided is a Spodoptera frugiperda pupa ovary cell line with high Baculovirus production. The cell line has the name of IOZCAS-Sf-1 and the deposit number of CGMCC No. 21014. Further disclosed are a method for preparing the cell line an...  
WO/2023/133490A1
Aspects of the disclosure relate to modified skin commensal bacterial host cells capable of producing terpenes.  
WO/2023/131336A1
Provided is a modified bacterium with anti-tumour activity, the bacterium containing an essential gene expression cassette controlled by a strict hypoxia-inducible promoter; the bacterium is missing at least one gene involved in or regul...  
WO/2023/131656A1
Provided are mutant Chlorella vulgaris strains, which comprise no detectable chlorophyll. Further provided are compositions and products, in particular food products, comprising biomass from the mutant strains, as well as methods for pro...  
WO/2023/126028A2
Provided in the present invention are a microbial strain of Lachnospiraceae, a drug for preventing and/or treating at least one disease of tumors, metabolic diseases, diabetes, autoimmune diseases, infectious diseases, central nervous di...  
WO/2023/123082A1
A double-bacteria microbial agent comprising carbonate mineralization bacteria and carbonic anhydrase producing bacteria, a preparation method for the double-bacteria microbial agent, and a use in desertified soil remediation. Carbonate ...  
WO/2023/126461A1
The application concerns methods for improving a plant growth feature, such as biomass, height,yield, and/or emergence, of plants using certain fungi or agricultural active compositions comprising the fungi. Plants and plant parts treate...  
WO/2023/128531A1
The present invention relates to: a method for preparing a Hovenia dulcis Thunb fruit fermented vinegar having hangover relief and liver protection effects; and a beverage composition prepared using same as a main ingredient. In the meth...  
WO/2023/125831A1
Disclosed is a method for collecting microbial bodies from a bacterial or fungal fermentation culture solution. The method comprises the steps of: a) mixing the bacterial or fungal fermentation culture solution with carboxylated chitosan...  
WO/2023/124018A1
Provided are a Lactobacillus plantarum against helicobacter pylori infection and the use thereof. The Lactobacillus plantarum against Helicobacter pylori infection is named Lactobacillus plantarum Lp05 and was deposited in the China Gene...  
WO/2023/125992A1
Disclosed in the invention are a glutathione yeast, a preparation method and a use of the product. The production method comprises the following steps: after multi-stage seed cultivation of a glutathione yeast strain, the glutathione yea...  
WO/2023/124450A1
A new strain, Bacillus velezensis XDY021, with the deposit number of GDMCC No: 62146. The use of Bacillus velezensis XDY021 comprises a method for fermenting scraps in the food industry with an argyroneta aquatica bait raw material ferme...  

Matches 301 - 350 out of 54,843