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WO/2024/028276A1 |
The invention relates to methods for determining the prognosis of a patient suffering colorectal cancer, for selecting an adjuvant chemotherapy for said patient and for selecting a patient suffering colorectal cancer to receive adjuvant ...
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WO/2024/029625A1 |
This medicine contains, as an active ingredient, an ETS1 inhibitor that inhibits the expression or function of ETS Proto-Oncogene 1, Transcription Factor (ETS1) in a fibroblast-specific manner.
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WO/2024/028451A1 |
A method of additively manufacturing a sensor is provided. The method comprises providing a working electrode and a reference electrode, wherein the reference electrode and the working electrode comprises a conductive agent composition; ...
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WO/2024/028732A1 |
Provided are novel multispecific antibodies comprising at least one of a first antigen-binding region and a second antigen-binding region each capable of binding specifically to human epidermal growth factor receptor 2 (HER2), and a thir...
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WO/2024/028217A1 |
The invention relates to a method and a gas sensor for ascertaining the concentration of a gas component in a gas mixture. The gas sensor (100) comprises a heating device (110), which is designed to heat the gas mixture, and a temperatur...
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WO/2024/029556A1 |
[Solution] A filter 10 comprises: a base material 20 that is composed of porous polyurethane, in which a plurality of fine pores are formed; and an active group 28 that is fixed to a surface 26 of the base material 20 and is capable of f...
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WO/2024/030973A1 |
The present application provides, in some aspects, methods of identifying a stimulus for a condensate modulatory characteristic for one or more condensate types, such as to identify a selective condensate modulator. In other aspects, als...
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WO/2024/030987A1 |
A method for measuring an oil saturation value of a subterrain formation uses a tool having multiple dual-function detectors that detect neutrons and gamma rays. The method includes emitting neutrons into the formation, detecting neutron...
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WO/2024/030898A2 |
The present disclosure relates to labeling of proteins for evaluating changes in microtubule structure. Included are compositions and methods that permit detection of shortening and/or lengthening of microtubules for research, diagnostic...
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WO/2024/026229A1 |
A biochip includes a perfusion layer between a media layer and a first membrane. The perfusion layer has a perfusion channel to provide a liquid to cells in a well layer, with the cells attached to a second membrane below the well layer....
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WO/2024/021694A1 |
A method for evaluating milk products according to lipidic components, being performed in the following steps: (1) establishing a local breast milk database; (2) collecting a milk product sample to be evaluated; (3) determining the conte...
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WO/2024/026026A1 |
Disclosed herein include methods for screening of lipid nanoparticles (LNPs) for mRNA delivery in vivo. The methods, compositions and systems disclosed herein allows, for example, screening of LNPs for organ-specific or tissue cell type-...
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WO/2024/025260A1 |
The present invention relates to: a fluorescent probe compound represented by chemical formula 1 or chemical formula 2; and a composite comprising bioceramics, and a fluorescent probe compound represented by chemical formula 1 and/or a f...
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WO/2024/025365A1 |
A biosensor cartridge is disclosed. The biosensor cartridge, which detects biological material so as to generate an electrochemiluminescence signal, according to one aspect of the present invention, comprises: an electrode unit including...
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WO/2024/022320A1 |
The present invention provides a system for performing high-throughput selection of cell masses from a source, fabrication of biomaterial-encapsulated cell mass model based on the selected cell masses, and separation of biomaterial-encap...
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WO/2024/023317A1 |
The present disclosure relates to methods of detecting metabolites using a microfluidic capillary electrophoresis-mass spectrometry (CE-MS) system. The metabolites can be useful to diagnosis diseases or disorders, as well as to monitor t...
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WO/2024/020690A1 |
A device or method for affinity binding on an aluminum oxide surface. A biomolecule provides for immobilizing on the aluminum oxide surface. The biomolecule includes a histidine rich domain, a metal binding domain, or a metal binding moi...
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WO/2024/021664A1 |
The present invention provides an immunochromatographic test strip capable of changing color for indication and a use method thereof. The immunochromatographic test strip comprises a bottom plate and a sample pad, a combination pad, a re...
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WO/2024/022516A1 |
The present invention provides an anti-CD28 humanized single-domain antibody. Specifically, disclosed are a plurality of single-domain antibodies targeting CD28 and humanized antibodies thereof, derived proteins, gene sequences encoding ...
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WO/2024/022794A1 |
The invention relates to a device (1) for detecting a substance, in particular an explosive substance. A flow (30) is directed in the direction of a surface (12) of a sample receiving assembly (10), and a person (2) to examine the substa...
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WO/2024/023324A1 |
The disclosure relates to a combination of biomarkers comprising at least: (i-a) one biomarker selected in each of the following group of biomarkers: Patient's age, Plasma steroids, and Urinary steroids, and at least one biomarker select...
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WO/2024/025916A2 |
This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having mesothelioma (e.g., pleural mesothelioma). For example, methods and materials that can be used to determine whether or not a mamma...
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WO/2024/025049A1 |
An incubation inspection system according to one embodiment of the present invention may comprise: a housing having a predetermined inner space to include at least one component; a plurality of storage plates that accommodate a plurality...
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WO/2024/023823A1 |
There is provided a water quality probe system, the system comprising: one or more water contact sensors; a geolocation unit; a processing circuitry (PC), operably connected to the one or more water contact sensors and to the geolocation...
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WO/2024/024955A1 |
Provided is a method for producing a vagus-nerve-like parasympathetic nerve cell, the method comprising (a) a step for inducing the differentiation of a pluripotent stem cell into a parasympathetic nerve cell, and (b1) a step for introdu...
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WO/2024/026307A1 |
This disclosure provides biomarkers for diagnosing post-acute sequelae of COVID-19 (PASC). In some embodiments, the biomarker comprises phosphocreatine (PCr) recovery time. In some embodiments, the subject suffering from PASC has a longe...
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WO/2024/023641A1 |
The present invention relates to methods of identifying a subject for treatment with or treating a subject with a tricyclic AKR1C3 dependent KARS inhibitor of formula (I), or a pharmaceutically acceptable salt thereof. The methods may co...
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WO/2024/023368A1 |
The invention relates to a method for the prediction of an increase of dipeptidyl peptidase 3 (DPP3) in a critically ill patient. In particular, the method comprises providing a sample from said patient, determining a level of Dipeptidyl...
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WO/2024/023390A1 |
The present invention relates to a nanosensor comprising a porous nanoparticle with at least one pore, a marker located therein, and a molecular doorway, such that access to the outside of the pore is unblocked in the presence of scopola...
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WO/2024/023827A1 |
A method of activating an immune response against brain metastasis in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an inhibitor of an MCP-1/CCR2/CCR4 axis...
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WO/2024/026115A2 |
The present invention is directed to a protein aggregation assay, and methods of use thereof.
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WO/2024/020646A1 |
Disclosed are methods for assessing the likelihood of a subject having resistance to coronavirus infection (eg a SARS-CoV-2 infection). More particularly, the present application discloses methods for assessing the likelihood of a subjec...
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WO/2024/025923A1 |
The present disclosure provides methods for assessing responsiveness or non-responsiveness to a therapeutic agent (e.g., ICB therapy and/or anti-angiogenic) in subjects having a cancer or tumor based on angio-immune panel signatures. The...
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WO/2024/025967A1 |
Methods, systems, and computer readable media for quantifying cells having expressed BCMA are provided. In aspects, a whole blood sample is mixed with a mixture of fluorophores to obtain a blood sample mixture, each fluorophore in the mi...
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WO/2024/021686A1 |
An ultra-sensitive nanopore structure, a chip, an analysis device, an amino acid detection method, a protein detection method, and a use. The ultra-sensitive nanopore structure relates to a nanopore (8); the pore diameter of the nanopore...
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WO/2024/020697A1 |
Provided are systems, cartridges, devices and methods for detecting a target analyte in a test sample. The system employs a multitude of magnetic sources for moving magnetic beads in a sequential movement through various portions of e.g....
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WO/2024/024180A1 |
An analysis assistance method for providing assistance in analysis of stained images of a specimen, the method comprising: a step for preparing a plurality of stained images that are obtained by staining a single specimen using different...
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WO/2024/024565A1 |
The present invention addresses the problem of providing an agent that suppresses cell aging and a drug that prevents or treats diseases and the like caused by cell aging. More specifically, the present invention is a cell aging suppress...
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WO/2024/026420A1 |
Systems and methods for the identification of auto-antibodies associated with central nervous system or psychiatric disease or disorders. Also disclosed herein are methods of treating central nervous system or psychiatric disease or diso...
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WO/2024/023144A1 |
The present invention relates to the field of optical imaging. More particularly, it relates to fluorescent probes targeting carbonic anhydrase nine (CA-IX) comprising near-infrared (NIR) dyes of the cyanine. The invention also relates t...
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WO/2024/023758A1 |
Provided herein are methods of precipitating proteins within compositions that contain a protein and a polysorbate. These methods allow for an accurate determination of the concentration or the amount of polysorbate within the composition.
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WO/2024/023770A1 |
Systems, methods and devices analyze a urine by generating a urine data matrix based on urine spectrum received by a light detector from a light source or urine spectra received by a light detector from light sources. The generated urine...
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WO/2024/025962A1 |
The present disclosure relates to treating tumor tissue using magneto-immunotherapy (Mag-IT) techniques. For example, a method may include administering a magnetotherapy treatment to tumor tissue of a subject and administering an immune ...
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WO/2024/025986A1 |
The invention provides pharmaceutical compositions of anti-PD-1 antibodies or antigen-binding fragments thereof with less than or equal to about 3.0 % oxidation of Met105 in the CDRH3 heavy chain region, and PH20 variants or fragments th...
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WO/2024/026413A2 |
Methods, systems and kits useful for the detection and diagnosis of neurodegenerative diseases including Alzheimer's Disease (AD)- and early-stage Parkinson's Disease-related pathology, and methods of preparing labeled immunocomplexes us...
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WO/2024/025968A1 |
The present disclosure provides methods of treating multiple myeloma in a patient in need thereof comprising administering a gamma secretase and a B-cell maturation antigen (BCMA)-directed therapy to the patient.
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WO/2024/022478A1 |
An antibody specifically binding to CB1 or an antigen-binding fragment thereof, a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof, a nucleic acid molecule encoding the antibody or the antigen-bi...
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WO/2024/023534A1 |
A sensor for sensing analytes in blood comprising plasma and erythrocytes, the sensor comprising: an analyte sensor configured to sense an analyte in the blood and to output a response corresponding to the sensed analyte; and a separatio...
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WO/2024/025891A1 |
Devices and techniques for a system for simultaneous contractile force and calcium/voltage transient measurement of engineered tissue are generally described. The system for simultaneous contractile force and calcium/voltage transient me...
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WO/2024/023320A1 |
The present invention relates to a method of physico-chemical analysis of a gas sample comprising a carrier gas in which chlorine gas is diluted, the physico-chemical analysis method comprising: a) a step of converting the chlorine of th...
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