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Matches 451 - 500 out of 222,668

Document Document Title
WO/2024/028276A1
The invention relates to methods for determining the prognosis of a patient suffering colorectal cancer, for selecting an adjuvant chemotherapy for said patient and for selecting a patient suffering colorectal cancer to receive adjuvant ...  
WO/2024/029625A1
This medicine contains, as an active ingredient, an ETS1 inhibitor that inhibits the expression or function of ETS Proto-Oncogene 1, Transcription Factor (ETS1) in a fibroblast-specific manner.  
WO/2024/028451A1
A method of additively manufacturing a sensor is provided. The method comprises providing a working electrode and a reference electrode, wherein the reference electrode and the working electrode comprises a conductive agent composition; ...  
WO/2024/028732A1
Provided are novel multispecific antibodies comprising at least one of a first antigen-binding region and a second antigen-binding region each capable of binding specifically to human epidermal growth factor receptor 2 (HER2), and a thir...  
WO/2024/028217A1
The invention relates to a method and a gas sensor for ascertaining the concentration of a gas component in a gas mixture. The gas sensor (100) comprises a heating device (110), which is designed to heat the gas mixture, and a temperatur...  
WO/2024/029556A1
[Solution] A filter 10 comprises: a base material 20 that is composed of porous polyurethane, in which a plurality of fine pores are formed; and an active group 28 that is fixed to a surface 26 of the base material 20 and is capable of f...  
WO/2024/030973A1
The present application provides, in some aspects, methods of identifying a stimulus for a condensate modulatory characteristic for one or more condensate types, such as to identify a selective condensate modulator. In other aspects, als...  
WO/2024/030987A1
A method for measuring an oil saturation value of a subterrain formation uses a tool having multiple dual-function detectors that detect neutrons and gamma rays. The method includes emitting neutrons into the formation, detecting neutron...  
WO/2024/030898A2
The present disclosure relates to labeling of proteins for evaluating changes in microtubule structure. Included are compositions and methods that permit detection of shortening and/or lengthening of microtubules for research, diagnostic...  
WO/2024/026229A1
A biochip includes a perfusion layer between a media layer and a first membrane. The perfusion layer has a perfusion channel to provide a liquid to cells in a well layer, with the cells attached to a second membrane below the well layer....  
WO/2024/021694A1
A method for evaluating milk products according to lipidic components, being performed in the following steps: (1) establishing a local breast milk database; (2) collecting a milk product sample to be evaluated; (3) determining the conte...  
WO/2024/026026A1
Disclosed herein include methods for screening of lipid nanoparticles (LNPs) for mRNA delivery in vivo. The methods, compositions and systems disclosed herein allows, for example, screening of LNPs for organ-specific or tissue cell type-...  
WO/2024/025260A1
The present invention relates to: a fluorescent probe compound represented by chemical formula 1 or chemical formula 2; and a composite comprising bioceramics, and a fluorescent probe compound represented by chemical formula 1 and/or a f...  
WO/2024/025365A1
A biosensor cartridge is disclosed. The biosensor cartridge, which detects biological material so as to generate an electrochemiluminescence signal, according to one aspect of the present invention, comprises: an electrode unit including...  
WO/2024/022320A1
The present invention provides a system for performing high-throughput selection of cell masses from a source, fabrication of biomaterial-encapsulated cell mass model based on the selected cell masses, and separation of biomaterial-encap...  
WO/2024/023317A1
The present disclosure relates to methods of detecting metabolites using a microfluidic capillary electrophoresis-mass spectrometry (CE-MS) system. The metabolites can be useful to diagnosis diseases or disorders, as well as to monitor t...  
WO/2024/020690A1
A device or method for affinity binding on an aluminum oxide surface. A biomolecule provides for immobilizing on the aluminum oxide surface. The biomolecule includes a histidine rich domain, a metal binding domain, or a metal binding moi...  
WO/2024/021664A1
The present invention provides an immunochromatographic test strip capable of changing color for indication and a use method thereof. The immunochromatographic test strip comprises a bottom plate and a sample pad, a combination pad, a re...  
WO/2024/022516A1
The present invention provides an anti-CD28 humanized single-domain antibody. Specifically, disclosed are a plurality of single-domain antibodies targeting CD28 and humanized antibodies thereof, derived proteins, gene sequences encoding ...  
WO/2024/022794A1
The invention relates to a device (1) for detecting a substance, in particular an explosive substance. A flow (30) is directed in the direction of a surface (12) of a sample receiving assembly (10), and a person (2) to examine the substa...  
WO/2024/023324A1
The disclosure relates to a combination of biomarkers comprising at least: (i-a) one biomarker selected in each of the following group of biomarkers: Patient's age, Plasma steroids, and Urinary steroids, and at least one biomarker select...  
WO/2024/025916A2
This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having mesothelioma (e.g., pleural mesothelioma). For example, methods and materials that can be used to determine whether or not a mamma...  
WO/2024/025049A1
An incubation inspection system according to one embodiment of the present invention may comprise: a housing having a predetermined inner space to include at least one component; a plurality of storage plates that accommodate a plurality...  
WO/2024/023823A1
There is provided a water quality probe system, the system comprising: one or more water contact sensors; a geolocation unit; a processing circuitry (PC), operably connected to the one or more water contact sensors and to the geolocation...  
WO/2024/024955A1
Provided is a method for producing a vagus-nerve-like parasympathetic nerve cell, the method comprising (a) a step for inducing the differentiation of a pluripotent stem cell into a parasympathetic nerve cell, and (b1) a step for introdu...  
WO/2024/026307A1
This disclosure provides biomarkers for diagnosing post-acute sequelae of COVID-19 (PASC). In some embodiments, the biomarker comprises phosphocreatine (PCr) recovery time. In some embodiments, the subject suffering from PASC has a longe...  
WO/2024/023641A1
The present invention relates to methods of identifying a subject for treatment with or treating a subject with a tricyclic AKR1C3 dependent KARS inhibitor of formula (I), or a pharmaceutically acceptable salt thereof. The methods may co...  
WO/2024/023368A1
The invention relates to a method for the prediction of an increase of dipeptidyl peptidase 3 (DPP3) in a critically ill patient. In particular, the method comprises providing a sample from said patient, determining a level of Dipeptidyl...  
WO/2024/023390A1
The present invention relates to a nanosensor comprising a porous nanoparticle with at least one pore, a marker located therein, and a molecular doorway, such that access to the outside of the pore is unblocked in the presence of scopola...  
WO/2024/023827A1
A method of activating an immune response against brain metastasis in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an inhibitor of an MCP-1/CCR2/CCR4 axis...  
WO/2024/026115A2
The present invention is directed to a protein aggregation assay, and methods of use thereof.  
WO/2024/020646A1
Disclosed are methods for assessing the likelihood of a subject having resistance to coronavirus infection (eg a SARS-CoV-2 infection). More particularly, the present application discloses methods for assessing the likelihood of a subjec...  
WO/2024/025923A1
The present disclosure provides methods for assessing responsiveness or non-responsiveness to a therapeutic agent (e.g., ICB therapy and/or anti-angiogenic) in subjects having a cancer or tumor based on angio-immune panel signatures. The...  
WO/2024/025967A1
Methods, systems, and computer readable media for quantifying cells having expressed BCMA are provided. In aspects, a whole blood sample is mixed with a mixture of fluorophores to obtain a blood sample mixture, each fluorophore in the mi...  
WO/2024/021686A1
An ultra-sensitive nanopore structure, a chip, an analysis device, an amino acid detection method, a protein detection method, and a use. The ultra-sensitive nanopore structure relates to a nanopore (8); the pore diameter of the nanopore...  
WO/2024/020697A1
Provided are systems, cartridges, devices and methods for detecting a target analyte in a test sample. The system employs a multitude of magnetic sources for moving magnetic beads in a sequential movement through various portions of e.g....  
WO/2024/024180A1
An analysis assistance method for providing assistance in analysis of stained images of a specimen, the method comprising: a step for preparing a plurality of stained images that are obtained by staining a single specimen using different...  
WO/2024/024565A1
The present invention addresses the problem of providing an agent that suppresses cell aging and a drug that prevents or treats diseases and the like caused by cell aging. More specifically, the present invention is a cell aging suppress...  
WO/2024/026420A1
Systems and methods for the identification of auto-antibodies associated with central nervous system or psychiatric disease or disorders. Also disclosed herein are methods of treating central nervous system or psychiatric disease or diso...  
WO/2024/023144A1
The present invention relates to the field of optical imaging. More particularly, it relates to fluorescent probes targeting carbonic anhydrase nine (CA-IX) comprising near-infrared (NIR) dyes of the cyanine. The invention also relates t...  
WO/2024/023758A1
Provided herein are methods of precipitating proteins within compositions that contain a protein and a polysorbate. These methods allow for an accurate determination of the concentration or the amount of polysorbate within the composition.  
WO/2024/023770A1
Systems, methods and devices analyze a urine by generating a urine data matrix based on urine spectrum received by a light detector from a light source or urine spectra received by a light detector from light sources. The generated urine...  
WO/2024/025962A1
The present disclosure relates to treating tumor tissue using magneto-immunotherapy (Mag-IT) techniques. For example, a method may include administering a magnetotherapy treatment to tumor tissue of a subject and administering an immune ...  
WO/2024/025986A1
The invention provides pharmaceutical compositions of anti-PD-1 antibodies or antigen-binding fragments thereof with less than or equal to about 3.0 % oxidation of Met105 in the CDRH3 heavy chain region, and PH20 variants or fragments th...  
WO/2024/026413A2
Methods, systems and kits useful for the detection and diagnosis of neurodegenerative diseases including Alzheimer's Disease (AD)- and early-stage Parkinson's Disease-related pathology, and methods of preparing labeled immunocomplexes us...  
WO/2024/025968A1
The present disclosure provides methods of treating multiple myeloma in a patient in need thereof comprising administering a gamma secretase and a B-cell maturation antigen (BCMA)-directed therapy to the patient.  
WO/2024/022478A1
An antibody specifically binding to CB1 or an antigen-binding fragment thereof, a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof, a nucleic acid molecule encoding the antibody or the antigen-bi...  
WO/2024/023534A1
A sensor for sensing analytes in blood comprising plasma and erythrocytes, the sensor comprising: an analyte sensor configured to sense an analyte in the blood and to output a response corresponding to the sensed analyte; and a separatio...  
WO/2024/025891A1
Devices and techniques for a system for simultaneous contractile force and calcium/voltage transient measurement of engineered tissue are generally described. The system for simultaneous contractile force and calcium/voltage transient me...  
WO/2024/023320A1
The present invention relates to a method of physico-chemical analysis of a gas sample comprising a carrier gas in which chlorine gas is diluted, the physico-chemical analysis method comprising: a) a step of converting the chlorine of th...  

Matches 451 - 500 out of 222,668