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WO/2018/186434A1 |
Provided is an age-related macular degeneration (AMD) risk evaluation method that is capable of estimating the AMD morbidity risk of a subject with high precision, does not present shortcomings such as early degeneration or high cost as ...
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WO/2018/185319A1 |
The present invention relates to a composition for the preparation and pre-microbiological analysis of a sputum specimen, wherein the composition comprises a mucolytic agent in the form of a dithioamine such as, but not limited to, dithi...
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WO/2018/185322A1 |
The present invention relates to a method for determining the fertility of spermatozoa, said method comprising determining the total content of Vimentin variant 3 (Vim3) per spermatozoon and/or the spatial localization of the Vim3 in the...
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WO/2018/187790A2 |
Provided is a biomonitoring device that measures a parameter of a material expelled during use of a toilet by a user. Also provided is a biomonitoring mirror device that identifies a user, detects a febrile illness in a user, dispenses m...
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WO/2018/186267A1 |
Provided are: a coloring cellulose microparticle enabling false positive to be significantly reduced while maintaining a high detection sensitivity; and an immunochromatographic diagnostic kit using the same. The present invention provid...
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WO/2018/187311A1 |
The present disclosure provides biomarkers and methods for providing a clinical assessment of a subject. In particular, the present disclosure provides methods for measuring at least one biomarker to classifying a subject as being test n...
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WO/2018/187259A1 |
The present invention relates, in part, to methods and compositions for enhancing anti-tumor immune responses. Particularly, the invention provides methods for enhancing the immune functions of Fc receptor (FcR)-expressing cells includin...
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WO/2018/187011A1 |
A test apparatus that guides an end user through visualization of a user interface on a web browser that is easy to operate for individuals with limited knowledge of the devices or test protocols for gas meters. The test apparatus may in...
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WO/2018/186052A1 |
A diagnostic imaging assistance device according to the present invention executes: a process for receiving an image of tissue or cells; a process for extracting a feature amount of the tissue or cells from an image to be processed; a pr...
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WO/2018/185226A1 |
A gas sensor (1) comprises a sensing element (11) of a material including metal oxide and is sensitive to a target gas and to a recalibration gas different from the target gas. For recalibrating the gas sensor (1), a resistance of the se...
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WO/2018/187786A1 |
The present invention relates to a unipotent neutrophil progenitor population, to methods of preparing and using same. In certain embodiments, the neutrophil progenitor population have at least the phenotype CD45+, CD41-, CD127 (IL-7Rα)...
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WO/2018/185510A1 |
The present invention relates to method for assessing the H2S release capacity of a liquid sample containing one or more sulfur compounds which are able to be degraded into gaseous H2S with temperature, said method comprising the followi...
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WO/2018/187332A1 |
The disclosure provides methods of treating a malignancy comprising administering an effective dose of a chimeric receptor (e.g., CAR or TCR) genetically modified T cell immunotherapy. Some aspects of the disclosure relate to methods of ...
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WO/2018/186731A1 |
A diagnostic kit for a confirmatory assay using the indirect ELISA method that measures the levels of anti-native hapten antibodies produced in an actual infection, thereby preventing large financial losses to the farm, by discerning fal...
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WO/2018/185336A1 |
The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour...
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WO/2018/187348A1 |
The present disclosure relates to a red blood cell (RBC) solution comprising ethylenediaminetetraacetic acid (EDTA) and methods for making and using the same. The solution can comprise EDTA at a concentration from 3-5 g/L, including 4 g/...
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WO/2018/187385A1 |
The present disclosure relates generally to detection of molecular biomarkers in a sample or diagnosis of a subject based upon detection or quantification of molecular biomarkers in a sample, specifically to the identification and use of...
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WO/2018/185781A1 |
The present invention relates to the detection and isolation of target cells based on microfluidics and cell sorting technology (MicroFACS). In this method the biological cells and microparticles are encapsulated inside hydrodynamically ...
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WO/2018/184935A1 |
The concentration of calprotectin in a sample can be determined with improved accuracy using a particle enhanced turbidimetric immunoassay, said assay comprising anti-calprotectin antibodies or fragments thereof, immobilized to particles...
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WO/2018/187423A1 |
The present disclosure provides methods and reagents useful for analyzing protein-protein interfaces such as interfaces between a presenter protein (e.g., a member of the FKBP family, a member of the cyclophilin family, or PIN1) and a ta...
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WO/2018/187733A1 |
An apparatus for biological analysis includes a substrate, and an ion-permeable material with a textured surface on a first side of the ion-permeable material. The substrate is disposed proximate to a second side of the ion-permeable mat...
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WO/2018/185301A1 |
Cell based assays are required for the detection of biological activity and hence are required for use as potency assays, detection of neutralizing antibodies and detection and quantification of the effector cell function of therapeutic ...
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WO/2018/185112A1 |
The present invention relates to an analytical in vitro process for predicting the therapeutic effectiveness of at least one pharmaceutical compound in the treatment of leukemia and/or lymphoma, the process analysing the transmembrane po...
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WO/2018/186657A1 |
Disclosed is a biochip that can discernably detect and analyze multiple bonds and single bonds of a protein. A biochip according to one embodiment comprises a sensing area in which a hydrogel functional layer having a binding mediator fo...
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WO/2018/185155A1 |
The invention relates to a mobile device having a housing which encloses said device, and comprising - a speaker arranged in the housing, in a housing section, wherein said housing section comprises a sound outlet in the form of air-perm...
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WO/2018/185942A1 |
The present invention relates to a method for manufacturing a purified product of a protein-modified phosphor-integrated particle, a method for manufacturing a fluorescent staining liquid, a purified product of a protein-modified phospho...
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WO/2018/185487A1 |
The present invention discloses a specific, rapid test differentiating microorganisms by trait, such as distinguishing gram positive and gram negative bacteria, in bodily fluids at point of care. This is achieved through a method of prod...
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WO/2018/184115A1 |
Compounds comprising quinazolinone derivatives and methods of identification and use of imaging agents. The compounds have the general formula I: wherein R2 is selected from halogen, halosubstituted alkyl, alkyl, hydroxyl-alkyl, and amin...
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WO/2018/186120A1 |
This evaluation method evaluates a cell mass CM in which a plurality of cells have aggregated, and comprises: an imaging step for capturing an image of light obtained from the cell mass CM by irradiating the cell mass CM with light; an a...
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WO/2018/187227A1 |
Disclosed are methods and kits for treating patients, particularly cancer patients, using bavituximab in combination therapies with immuno-oncology (IO) agents such as checkpoint inhibitor antibodies. The methods and kits are based on th...
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WO/2018/184112A1 |
Methods for the assessment of colorectal polyps in general, and adenomatous polyps in particular, by mass spectrometry based measurement of metabolites in urine are described. In some embodiments, certain metabolites are identified as be...
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WO/2018/185439A1 |
The invention relates to a method for preparing cellular microcompartments comprising a hydrogel capsule enclosing a cluster of lymphomatous cells. The invention also relates to such a cellular microcompartment and its use in screening f...
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WO/2018/184382A1 |
Provided is a microfluidic chip for separating and detecting whole blood samples, comprising a chip body provided with a sample flow channel. The sample flow channel comprises a sample injection zone, a sedimentation zone, a mixing zone,...
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WO/2018/187536A1 |
A device for application of even pressure on a plunger head includes: a center rod with a pressure plate affixed at a first end and a back plate positioned adjacent to a second end; a positioning spring adjacent to the pressure plate at ...
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WO/2018/186683A1 |
The present invention relates to a biosensor substrate, a method for producing same, and a biosensor comprising same.
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WO/2018/187687A1 |
Integrated diagnostic devices comprising peptide-DNA conjugates for analyte detection, an embedded biomolecular computing system for sample analysis, and a layered device architecture are provided herein. In particular, provided herein a...
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WO/2018/185378A1 |
A measuring apparatus (200) comprises: - an input (201) to receive an aerosol sample (FG1), - a modifier unit (100) to provide a modified sample (MG1) by removing particles (P1) of the aerosol sample (FG1), and - a sensor unit (SEN1) to ...
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WO/2018/186829A1 |
A cassette may include a substrate and a die coupled to the substrate wherein the substrate is made of modified polyetherimide (PEI). A system for ejecting a fluid into an assay may include at least one dispense head, the at least one di...
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WO/2018/186104A1 |
Provided is a method for quantifying urea in a sample solution with a colorimetric method using diacetylmonoxime, wherein a reagent formulated for use in reaction is refrigerated, and the refrigerated reagent is used to quantify urea. In...
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WO/2018/187295A1 |
Near infrared and shortwave infrared dyes can have polymethine structures.
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WO/2018/187629A1 |
Disclosed herein are ratiometric fluorescence imaging reagents, and image processing methods for using fluorescence ratio and intensity thresholds to detect and visualize regions of biological activity in biological specimens with improv...
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WO/2018/185068A1 |
A sample holder (100) comprising a main body (1) comprising a first cavity (7), the first cavity comprising a bottom and an open end, a sample supporting element (2) comprising a receiving surface made of metal, the sample supporting ele...
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WO/2018/186676A1 |
The present invention relates to an apparatus and a method for separating a target cell. An apparatus for separating a target cell according to an embodiment of the present invention is a microfluidic apparatus that is mounted on a rotat...
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WO/2018/186481A1 |
The purpose of the present invention is to obtain a ketogenic diet monitoring device for individually managing ketogenic diet efficacy in animals. This ketogenic diet monitoring device is configured to monitor by measuring, once or multi...
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WO/2018/186682A1 |
The present invention relates to a biosensor substrate, a method for producing same, and a biosensor comprising same.
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WO/2018/185164A1 |
Disclosed is apparatus for collecting a breath sample from a human subject, the apparatus comprising at least a mask portion which, in use, is positioned over the subject's mouth and nostrils so as to collect breath exhaled from the subj...
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WO/2018/184084A1 |
The present invention relates to a process for producing tick embryonic stem-like cells and the tick embryonic stem-like cells produced by said process. Furthermore, the present invention relates to methods for replicating microorganisms...
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WO/2018/184113A1 |
There is described herein imidopiperidine compounds as inhibitors of human polynucleotide kinase phosphatase.
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WO/2018/184957A1 |
A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers...
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WO/2018/185573A1 |
A diagnostic system performs disease diagnostic tests using at least an optical property modifying device and a mobile device. A user provides a biological sample from a patient to the optical property modifying device that reacts with a...
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