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WO/2019/051103A1 |
Methods and systems to perform genetically variant protein analysis and related marker genetic protein variations and databases, which in several embodiments allow performing a reliable genetic variation protein analysis in biological sa...
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WO/2019/047042A1 |
An alarming method for a platelet aggregation sample, comprising the following steps: providing a blood sample; controlling a first reaction condition, preparing the blood sample into a first sample to be tested, acquiring a test signal ...
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WO/2019/051107A1 |
A wearable device for multiplexed sweat analysis includes a sensing module. The sensing module includes multiple compartments, including a first compartment configured to induce sweat and sense a target analyte, and a second compartment ...
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WO/2018/035059A9 |
Provided herein are methods for determining the serotype of a virus particle and/or or determining the heterogeneity of a virus particle (e.g., an AAV particle). In other embodiments, the invention provides methods to determine the heter...
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WO/2019/051158A1 |
Provided are methods of administering glycerol phenylbutyrate to a patient in need thereof, wherein said patient is also being treated with a CYP3A4 substrate having a narrow therapeutic index, midazolam or a pharmaceutically acceptable ...
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WO/2019/048485A1 |
The present invention relates to a portable system (1) for sampling and physicochemical analysis of a fluid, comprising a fluidic circuit, wherein the fluidic circuit comprises: a sampling module (2) configured to collect a sample of a f...
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WO/2019/050478A1 |
Disclosed herein is a clear cell renal cell carcinoma (ccRCC) biomarker comprising at least 2 biomarkers selected from the group consisting of ZNF395, SMPDL3A, SLC28A1, SLC6A3, VEGFA, EGLN3, wherein at least one of the two biomarkers is ...
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WO/2019/049974A1 |
The purpose of the present invention is to develop a method capable of evaluating T-cell immune function. A method for evaluating T-cell immune function, said method characterized by detecting and quantifying soluble PD-L1 having a capac...
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WO/2019/050150A2 |
According to an embodiment of the present invention, provided is a screening method, for a lung cancer patient having acquired resistance to an EGFR therapeutic agent, by means of optical image analysis of blood circulating cancer cells ...
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WO/2017/211896A9 |
The invention provides a method for determining a systemic lupus erythematosus-associated disease state in a subject comprising the steps of (a) providing a sample to be tested; and (b) measuring the presence and/or amount in the test sa...
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WO/2019/048588A1 |
The present invention pertains to a new method for the diagnosis, prognosis, stratification and/or monitoring of a therapy, of cancer, preferably colorectal cancer, in a patient. The method is based on the determination of the level of a...
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WO/2019/051397A1 |
Provided herein are compositions including aptamers capable of binding to and/or inhibiting the activity of nucleolin. Methods of treating cancer in a subject by administering such compositions are also provided. Further provided are met...
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WO/2019/050458A1 |
The invention relates to a method for assessing the efficacy of an immunotherapy comprising administration of GAD to a patient, comprising the following steps: measuring at least one of GADA IgG subclass distribution; GADA levels; distri...
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WO/2019/051254A1 |
Bead arrays suitable for analysis by mass spectrometry are disclosed. In an embodiment, a bead array includes multiple reactive sites, each of the reactive sites being capable of binding multiple distinct target analytes.
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WO/2019/048503A1 |
The invention relates to an in vitro method for predicting the risk for transplant rejection in a transplanted subject. The inventors have shown that innate immune effectors NK cells could trigger microvascular inflammation and chronic t...
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WO/2019/048927A2 |
Provided herein, in some embodiments, are methods and compositions for detecting differentially expressed genes in a sample obtained from a subject having or at risk for preeclampsia.
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WO/2019/048965A1 |
Provided is a physical property prediction method with which anyone can easily and accurately predict the physical properties of an organic compound. Also provided is a physical property prediction system with which anyone can easily and...
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WO/2019/050935A1 |
The invention generally relates to methods and kits for the detection of human folate receptor 1 in a sample. Peptides of human folate receptor 1 are further provided.
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WO/2019/050017A1 |
The purpose of the present invention is to provide a substrate for a biochip, a biochip, a method for manufacturing a biochip, and a method for preserving a biochip. The present invention pertains to a biochip having: a substrate having ...
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WO/2019/049817A1 |
[Problem] The present invention addresses the problem of providing a sensor chip and the like which achieves both heat resistance/chemical resistance and inexpensive manufacturability, and is capable of exciting a waveguide mode. [Soluti...
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WO/2019/050362A2 |
The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vec...
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WO/2019/050036A1 |
The present invention provides: a peptide that includes a partial amino acid sequence of the C16orf74 protein, includes the cysteine at position 7 and/or the cysteine at position 14 of the C16orf74 protein, and inhibits dimer formation o...
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WO/2019/048727A1 |
An apparatus (600) for determining, by electrical tomography, vertical profile of an electrical property of interest of material(s) in a target volume (618) comprises a measurement probe (610) to be positioned at a plurality of different...
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WO/2019/051398A1 |
A method for the determination of antibiotic susceptibility through stimulated Raman scattering microscopy is disclosed. The method utilizes a imaging apparatus adapted to collect a laser signal through a sample having a bacteria for ima...
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WO/2019/050273A1 |
The present invention relates to a method for diagnosing pancreatic cancer using methionyl-tRNA synthetase and an acinar cell-specific marker. MRS has a higher level of diagnostic accuracy than conventional pancreatic cancer markers such...
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WO/2019/051090A2 |
Methods for diagnosis or prognosis of a cancer in a subject are provided and include the steps of: obtaining a biological sample from a subject; determining an amount of a phosphorylation at a Y260 residue in a Na/K ATPase present in the...
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WO/2019/049960A1 |
By analyzing intestinal bacterial flora, the present inventors found intestinal bacteria specific to depression symptoms. Detection of these bacteria enables differential diagnosis of depression symptoms associated with neuropsychiatric ...
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WO/2019/050420A1 |
The subject-matter of this invention is a method for the isolation of the biogenic amines from biological matrices, where the extraction procedure of seven biogenic amines and their precursor amino acids from the biological material comp...
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WO/2019/048859A1 |
A sensor array comprising at least two sensors, wherein each sensor comprises a protein barrel and a reporter dye; wherein the protein barrel defines a lumen; the reporter dye is bound to the lumen reversibly; and wherein the protein bar...
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WO/2019/048087A1 |
Method and device for extraction of markers, comprising: introducing a sample into a removable support basket placed in the housing of a cell of an extraction device provided with a flexible membrane and immersing the tissue sample in a ...
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WO/2019/048221A1 |
The invention relates to a method for analysing a gas, in which a sensitive layer (2) containing metal oxide is exposed to the gas, comprising the steps of: reducing the temperature of the sensitive layer (2) from a first temperature (T1...
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WO/2019/046896A1 |
The present disclosure relates to methods and markers for assessing cancer progression. In certain embodiments, the present disclosure provides a method of assessing progression of a cancer disease associated with increased or undesired ...
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WO/2019/051092A2 |
Methods of using biomarkers in determining the efficacy of a treatment for an organic acidemia in a subject are disclosed herein. Methods of using biomarkers in determining the efficacy of a liver-directed treatment for an organic acidem...
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WO/2019/050837A1 |
A system for monitoring an analyte concentration in liquid is provided. The system includes a coupon comprising an absorbent body with a window through the absorbent body wherein the liquid is maintained in said window by capillary actio...
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WO/2019/050890A1 |
Provided herein are methods and compositions, including synergistic combinations, for the treatment of tuberculosis.
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WO/2019/047498A1 |
Provided are a whole blood plasma separation system and method. The system comprises: a first blood separation apparatus and a second blood separation apparatus. The first blood separation apparatus comprises a blood collection unit and ...
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WO/2019/051181A1 |
The present invention generally relates to nanosensors for determination of molecules and other features, e.g., via surface plasmonic resonance, electric resonance, magnetic resonance, color changes, or the like. These articles and metho...
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WO/2019/049705A1 |
In order to provide a simple and highly accurate pathological index for Alzheimer's disease, this Alzheimer's disease diagnosis device is provided with: a measurement means for measuring, in peripheral blood, one or more selected from th...
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WO/2019/048899A1 |
The invention relates to a method for determining at least one property of hydrocarbon fluid, comprising: (a) providing a first chamber (1 ) filled with the hydrocarbon fluid and a second chamber (2) which is substantially empty, each of...
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WO/2019/051001A1 |
Described herein are compositions and methods for signaling and antigen-presenting bifunctional receptors (SABRs) comprising one or more antigen presenting domains; and one or more signal transduction domains, wherein the one or more ant...
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WO/2019/050802A1 |
This disclosure is directed to methods and devices (300) associated with Point of Care medical testing and diagnostics. More specifically, methods and devices are described which provide a quick and streamlined way to prepare blood sampl...
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WO/2019/050275A1 |
The present invention relates to a method for diagnosing pancreatic cancer using methionyl-tRNA synthetase (MRS). When used as a pancreatic cancer marker, MRS has a significantly higher level of diagnostic accuracy than conventional panc...
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WO/2019/050966A2 |
A number of methods and computer systems related to mass spectrometric data analysis are disclosed. Adoption of the disclosure herein facilitates automated, high throughput, rapid analysis of complex datasets such as datasets generated t...
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WO/2019/048450A1 |
The present invention relates to sulfoxide-based reagents suitable in the mass spectrometric determination of analyte molecules such as peptides as well as adducts of such reagents and analyte molecules and applications of said reagents ...
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WO/2019/051496A1 |
An imaging system that is configured to automatically obtain and provide two and three-dimensional digital images of various types of objects (e.g., tissue specimens, animals, electrical devices, etc.) for use in analysis thereof in a ma...
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WO/2019/051335A1 |
Provided herein are methods for tracking certain cells associated with a cell therapy, such as from a starting cell composition or a sample prior to administration to a subject and from a sample following administration to a subject. In ...
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WO/2018/215656A9 |
The present invention relates to a novel endoprotease, mutants thereof having binding but lacking or having reduced hydrolyzing activity, and use in methods of studying and isolating O-linked glycoproteins.
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WO/2019/049395A1 |
Provided is an analysis device, analysis method, or the like wherein the analysis device, when measuring a test liquid comprising an immunological reagent and a sample, carries out measurements even if as is, the sample is highly concent...
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WO/2019/048569A1 |
The present invention relates to a non-invasive, specific and rapid diagnostic method of Familial Mediterranean fever (FMF) in a subject said method comprising the step of measuring the level of cytokine (IL-18 or IL-1 beta) secreted by ...
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WO/2019/048124A1 |
The present invention relates to a process for quantitative determination of impurities in the form of fatty acid esters in aircraft turbine fuels, wherein the analyte is subjected to a chemical reaction selective therefor which affects ...
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