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WO/2019/097101A1 |
The present invention describes a new method for functionalising proteins by incorporating a metal fragment of high-performance rhenium, thus producing coordinated iminopyridines having three carbonyl groups in the fac position which pro...
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WO/2019/095011A1 |
A method of detecting the presence of a cathinone moiety in a sample, such as a suspected illicit drug sample, which comprises contacting the sample with a solution comprising neocuproine, a source of copper(II) and a catalyst and observ...
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WO/2018/222831A9 |
Described herein are methods for treating cancer. Aspects of the invention relate to administering to a subject a compound that targets a KDM4 or KDM5 family member, wherein the subject has at least one mutation in an epigenetic modifier...
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WO/2019/095403A1 |
Provided is a detection kit for an amyloid-β (Aβ) peptide. The kit comprises an anti-hemoglobin (Hb) antibody and an anti-Aβ antibody, wherein the anti-Hb antibody is a capture antibody and is used for capturing Hb, and the anti-Aβ a...
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WO/2019/097082A1 |
The invention generally relates to immunotherapy with chimeric antigen receptor (CAR}- engineered T-cells. In particular, the invention relates immunotherapy with chimeric antigen receptor (CAR)-engineered T-cells to target sub-populatio...
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WO/2019/055609A9 |
Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on qu...
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WO/2019/099341A1 |
The present disclosure describes methods and systems, including computer- implemented methods, computer program products, and computer systems, for measuring a water cut for hydrocarbon fluid in a production pipe. One method includes tra...
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WO/2019/098351A1 |
The present invention addresses the problem of providing a marker with which diabetic complications can be examined. Provided is a marker for examining diabetic complications which comprises a compound represented by formula (1), or a sa...
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WO/2019/099626A1 |
In one aspect, a method of estimating an HbA1c level is provided. The method may include obtaining a first and second glucose measurement, adding the first and the second glucose measurements to a glucose measurement data set, and calcul...
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WO/2018/064013A8 |
Disclosed are surprising new methods and kits for identifying and treating patients treatable with PS-targeting antibodies, particularly for identifying and treating cancer patients using bavituximab and bavituximab combination therapies...
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WO/2019/098673A1 |
A jig for pressing a gas analysis monocell according to the present invention comprises: a first plate and a second plate which face each other with a monocell therebetween; a first auxiliary pad positioned between the first plate and th...
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WO/2019/098643A1 |
The present invention relates to an apparatus for determining resistance of microorganisms, which may comprise: a storage unit including a database for storing first region mass spectrum data for a plurality of microorganisms and second ...
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WO/2019/099467A1 |
A rapid assay for determining the presence of bacteria in a sample, such as a contaminated food sample, is disclosed. The assay comprises contacting the sample with a bacteria-specific ligand associated with a substrate, wherein bacteria...
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WO/2019/097534A1 |
A method to assess the disease status, determine the mean/average control of the disease and monitor the compliance to treatment over a period of time of a respiratory disease, comprising of predicting the degree of airway inflammation a...
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WO/2019/099231A1 |
A method for sample preparation to quantify amines, the method comprising: (a) providing a hydrocarbon sample, wherein the hydrocarbon sample comprises a known standard; (b) loading the hydrocarbon sample onto a solid phase extraction (S...
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WO/2019/099387A1 |
A sensor for detecting non-hazardous and especially hazardous gases and/or vapors comprises a liquid crystal cell generally having a standard substrate and a conductive electrode layer thereon. An alignment layer is desirably located on ...
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WO/2019/099788A1 |
The disclosure provides methods, reagents, and kits for detecting, enriching, and using antigen-specific T regulatory (Treg) cells. The methods contacting T cells exposed to an antigen of interest (e.g., via MHC on an antigen presenting ...
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WO/2019/098517A1 |
The present invention relates to an indicator configured such that whether frozen food and food materials that are stored or circulated frozen have been thawed or not can be identified easily, conveniently, and visually. More particularl...
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WO/2019/099886A1 |
Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of pro...
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WO/2019/095943A1 |
A method for detecting and typing rare tumor cells having high metabolic activity in a body fluid sample, comprising the following steps: co-incubating nucleated cells in a body fluid sample with a first metabolic marker and a second met...
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WO/2019/100005A1 |
The present invention generally relates to methods of theranostic compounds and their use to selectively kill a class of cancer cells. Methods and means related to the treatment of cancers which overexpress the KRAS gene and/or eIF5A gen...
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WO/2019/060914A3 |
Methods, systems and related compositions are provided to perform single-cell marking of a nucleic acid and/or protein in a sample based on in-cell or in-organelle barcoding of nucleic acid and/or protein complexes of the cell or organel...
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WO/2019/097089A1 |
The present disclosure is related to the field of diabetes diagnostics. It introduces novel biomarkers that can be used to predict diabetes and detect presence of the disease. In addition, novel fatty acid biomarkers are presented.
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WO/2019/096852A1 |
The present invention relates to use of an isobaric label in mass spectrometry (MS) analysis using data-independent acquisition (DIA), wherein said isobaric label comprises or consists of a group which fragments in the mass spectrometer ...
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WO/2019/098682A1 |
The present invention relates to a novel anti-HER2 antibody or antigen-binding fragment thereof used in the prevention or treatment of cancer, a chimeric antigen receptor comprising the same, and uses thereof. The antibody of the present...
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WO/2019/099769A1 |
The present invention relates to the field of anastasis, i.e., the process of reversal of apoptosis. More specifically, the present invention provides methods and compositions useful for studying anastasis. In one embodiment, a tracking ...
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WO/2019/099671A1 |
Disclosed are methods of reducing age-dependent lysosome impairment and/or treating an age related neurodegenerative disease, fibrotic disease, or rheumatological disease in a subject comprising administering to the subject a therapeutic...
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WO/2019/099842A1 |
A point of care system may comprise a plurality of diagnostic engines and an IDM in electronic communication with each of the plurality of diagnostic engines. Each of the plurality of diagnostic engines may perform testing on a sample in...
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WO/2019/071384A8 |
Described herein are systems and methods of analyzing data acquired from a water plant, both historical and in real-time, making determinations about process and asset health diagnosis and anomaly detection using advanced techniques, and...
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WO/2019/098328A1 |
Provided are a kit for IgA nephropathy diagnosis, and an IgA nephropathy diagnostic agent, which include vimentin or a partial peptide thereof. Also provided is a data collection method for evaluating the possibility that a subject is af...
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WO/2019/096011A1 |
An MOS-transistor-based double-gate-regulated ultra-high-sensitivity biosensor comprises a detection system and a micro-channel system that are bonded with each other. The detection system comprises a substrate (8) and an ion implantatio...
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WO/2019/098301A1 |
This target molecule detection method involves: a step for preparing a fluid device provided with a substrate and a well array arranged on the substrate; a step for feeding into the fluid device well array a liquid in which target molecu...
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WO/2019/099453A1 |
A fully automatic online aero aluminum sorting and recovery system based on LIBS (Laser Induced Breakdown Spectroscopy) technology, which belongs to the field of aero aluminum sorting and recovery technology, and is suitable for online s...
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WO/2019/098207A1 |
The present invention provides a body fluid analysis device that makes it possible to analyze a body fluid such as urine more accurately than by visual observation and that can reduce the burdens of medical workers, etc. A body fluid ana...
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WO/2019/098288A1 |
Provided is: a novel antitumor agent which contains, as an active ingredient, a glutathione concentration-decreasing agent or a glutathione S-transferase inhibitor which is simultaneously administered with an effective amount of an aldeh...
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WO/2019/099999A1 |
The present disclosure generally relates to methods for detecting one or more analytes in a sample using immunoassays. In some embodiments, the disclosure provides methods that include quenching the free secondary antibody with a fractio...
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WO/2019/096340A2 |
The invention relates to a device for the on-site analysis of excrement, comprising a housing, a removal device, by means of which a sample of excrement can be removed. The removal device comprises an arm element for a sample carrier, wh...
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WO/2019/099706A1 |
Methods for diagnosing non-alcoholic steatohepatitis (NASH) and NASH with or without advanced liver fibrosis in a subject are provided, such methods including the detection of levels of a variety of biomarkers diagnostic of NASH versus s...
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WO/2019/098509A1 |
Provided according to an embodiment are a composition and a kit for diagnosis of breast cancer and a method for the diagnosis of breast cancer or for the provision of information for breast cancer diagnosis, using same. Thus, breast canc...
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WO/2019/098314A1 |
It was found that by treating a standard solution containing a steroid included in a cyclodextrin with a surfactant in a method for immunologically quantifying a steroid, is possible to desorb the steroid from the cyclodextrin, deviation...
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WO/2019/097958A1 |
The purpose of the present invention is to provide a substance which has a firmness improving action. The expression of adhesion molecules in at least one type of vascular endothelial cells selected from the group consisting of VE-cadher...
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WO/2019/095042A1 |
The utility of CD271 as a novel diagnostic and prognostic marker for SHH MB is demonstrated using immunohistochemical analysis as well as transcriptome data from 763 patient samples. Characterization of CD271 + and CD271- cells by RNA se...
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WO/2019/098680A1 |
An assembly-type blot strip device according to the present invention comprises: a holder which includes a base and side walls facing each other and formed in the height direction on both sides of the base, and in which blot strips are f...
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WO/2018/053166A3 |
Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and regeneration, yet not all integrin binding can lead to tissue repair. Here we show that through engineering hydrogel materials to promote α3/α5β...
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WO/2019/098194A1 |
Provided are a novel aging condition evaluation method, a novel information presentation method, and a novel screening method for a substance that ameliorates or prevents an aging condition. A method to evaluate an aging condition of a s...
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WO/2019/099653A1 |
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1comprising administering to a subject in need thereof a compound described here.
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WO/2019/098077A1 |
The purpose of the present invention is to provide: a water quality diagnostic system in which degrees of water quality abnormality can be diagnosed more accurately and more uniformly; a power generation plant; and a water quality diagno...
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WO/2019/036670A3 |
High quality vaccines are identified and formulated based on a threshold differential T-cell activation potential. The vaccines are mRNA vaccines formulated in a carrier, wherein the mRNA encodes an antigen.
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WO/2019/099096A1 |
Presented herein are systems and methods directed to a multispectral absorption-based imaging approach that provides for rapid and accurate detection, localization, and quantification of gas leaks. The imaging technology described herein...
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WO/2019/099856A1 |
Electrochemical aptamer-based (EAB) biosensing devices are described that provide drift correction and calibration to EAB sensor measurements of biofluid analyte concentrations by disclosing reference sensors that are configured to not i...
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