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WO/2018/064695A1 |
An apparatus (1) and a method for analysing a solid specimen material (2) by means of ablating particles (3) of the solid specimen material (2) by laser into a carrier liquid, having: – a specimen holder (5) for arranging the solid spe...
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WO/2018/060855A1 |
Certain configurations of a stable capacitor are described which comprise electrodes produced from materials comprising a selected coefficient of thermal expansion to enhance stability. The electrodes can be spaced from each other throug...
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WO/2018/060690A1 |
There is provided a method comprising separating a first population of ions according to a first physico-chemical property in a first separation device, and separating one or more groups of ions emerging from the first separation device ...
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WO/2018/056419A1 |
The objective of the present invention is the accurate quantitative analysis of the Ar element contained in a sample gas in an elemental analysis device combining a heating oven and a mass spectrometer for performing quantitative analysi...
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WO/2018/055815A1 |
An ion source adapter (30) for making it possible to use a mass spectrometer (20) that is used with voltage applied to a nebulizer (12) side of an ion source (10) for generating ions (18), with the nebulizer (12) side grounded, wherein t...
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WO/2018/056887A1 |
The present invention is related to a method to detect and speciate short-lived chemical substances such as organic radicals in natural and artificial gaseous environments. In short, positive charged reagent ions (AH+) are created in a s...
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WO/2018/056113A1 |
The present invention provides an interface device capable of highly efficiently introducing an ionized sample into a mass spectrometer. An ice droplet generation unit 11 forms ice droplets from a liquid sample supplied from a sample sup...
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WO/2018/055707A1 |
A mass spectrometer (1) is provided having: an ionization chamber (11) for generating ions from a sample; a collision cell (222) positioned in the stage after the ionization chamber (11); a mass separation unit (2412) positioned in the s...
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WO/2018/055483A1 |
Because most ion optics of mass spectrometry systems are subject to ion deposition and may exhibit significantly different behavior following substantial contamination (e.g., loss of sensitivity), fouled surfaces must be regularly cleane...
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WO/2018/058131A1 |
The combined capillary electrophoresis electrospray mass spectrometry apparatus has a circuit to handle excess current allows separations under a wide range of electrophoretic conditions. The apparatus includes an electrospray with an em...
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WO/2018/055347A1 |
A method of ion mobility spectrometry is disclosed comprising: transmitting a plurality of ions to an ion mobility separator 6; modulating the introduction of the ions into the ion mobility separator 6 at a first modulation frequency; se...
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WO/2018/050961A1 |
The invention shows a system for screening of traces of illicit substances that may be harmful, such as explosives, radioactive substances, toxics or drugs for example, from very tiny trace concentrations to be detected by means of mass ...
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WO/2018/053495A1 |
Mass spectrometry cartridge including a base in mechanical communication with a spray substrate holder, an absorbent pad between the base and the spray substrate holder, a translatable sample well holder interposed between the spray subs...
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WO/2018/050962A1 |
The invention relates to Multimethod ionization Device (MID) to utilize at least chemical ionization and a system further utilizing such a device provided with a reaction chamber for ion formation of reagent species (R1, R2) for adduct f...
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WO/2018/046906A1 |
A method of operating a quadrupole device is disclosed that comprises operating the quadrupole device in a first mode of operation, and operating the quadrupole device in a second mode of operation. Operating the quadrupole device in the...
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WO/2018/046083A1 |
The invention relates to an apparatus (1) and a method for analysing a chemical composition of aerosol particles. The apparatus (1) comprises an extractive electronspray ionisation source (2) for extracting components, in particular orga...
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WO/2018/046905A1 |
A method of operating a quadrupole device is disclosed that comprises operating the quadrupole device in a first mode of operation, passing ions into the quadrupole device while the quadrupole device is operated in the first mode of oper...
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WO/2018/046968A1 |
A method of carrying out mass spectrometry, comprising: using an electrostatic or electrodynamic ion trap to contain a plurality of ions, each ion having a mass to charge ratio, the ions having a first plurality of mass to charge ratios,...
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WO/2018/048494A1 |
An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation ...
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WO/2017/062102A9 |
Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes...
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WO/2018/045455A1 |
A device and method is described for analysing the elemental composition of a liquid sample utilizing a combination of electrochemical pre-concentration followed by spectrochemical analysis of analytes in a single device. The device cons...
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WO/2018/046619A1 |
The invention relates to an apparatus (1) and a method for analysing a chemical composition of aerosol particles. The apparatus (1) comprises an extractive electronspray ionisation source (2) for extracting components, in particular orga...
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WO/2018/044253A1 |
A system for expressing an ion path in a time-of-flight (TOF) mass spectrometer. The present invention uses two successive curved sectors, with the second one reversed, to form S-shaped configuration such that an output ion beam is paral...
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WO/2018/042325A1 |
A method for a structural characterization of polysaccharides, comprising steps of characterizing a polysaccharide by physical measurements comprising a determination of a mass of the polysaccharide by means of mass spectrometry, a furth...
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WO/2018/045208A1 |
Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and del...
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WO/2018/039102A1 |
Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the m...
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WO/2018/039135A1 |
Embodiments relate to an apparatus, method, or computer program. A laser may be configured to irradiate a plurality of laser pulses on a target area to ionize a sample placed in the target area into at least one ionized particle. Electro...
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WO/2018/037440A1 |
In this invention, an acceleration voltage generation unit (7) causes a direct-current high-voltage that is generated at a high-voltage power source unit (75) to be driven ON and OFF by a switch unit (74) to generate a high-voltage pulse...
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WO/2018/038734A1 |
An optical detection system for analyzing a fluid sample including a light source configured to emit a light beam to interact with the sample to form a spectrum, an optical fiber to transmit the spectrum, an array of single-photon detect...
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WO/2018/039137A1 |
Λη apparatus, method, or computer program. Spectrometer lest data of a sample may be received. The received test data may be matched to a reference library to determine characteristic information of the sample by correlating the test d...
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WO/2018/037240A1 |
There is provided a method of guiding ions, comprising providing an ion guide comprising a plurality of electrodes, confining ions radially within said ion guide by applying one or more voltages to said plurality of electrodes, applying ...
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WO/2018/033494A1 |
MASS ANALYSER HAVING EXTENDED FLIGHT PATH A time-of-flight or electrostatic trap mass analyzer is disclosed comprising: an ion flight region comprising a plurality of ion-optical elements (30-35) for guiding ions through the flight regio...
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WO/2018/029918A1 |
The present disclosure relates to an ion introducing interface structure of a mass spectrometer, and particularly to an airflow-limiting mass spectrometer ion introducing interface structure with a short tube structure. The ion introduci...
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WO/2018/029554A1 |
A plurality of measured product ion spectra is produced using a DIA tandem mass spectrometry method. One or more product ions are retrieved from a spectral library of known compounds or one or more theoretical product ions are calculated...
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WO/2018/031934A1 |
A method and means to produce a force for propulsion comprises a source of free electrons and a means to produce pseudoelectrons; whereas, a gravitating body such as the Earth provides a repulsive fifth force on the pseudoelectrons. Pseu...
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WO/2018/026910A1 |
Improved mass spectrometry-based apparatus and methods of analysis for analysing samples. A laser sampling system can be adapted to emit pulses of laser radiation at two or more wavelengths, wherein a first wavelength targets a first mat...
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WO/2018/026591A2 |
Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refin...
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WO/2018/025027A1 |
A method is disclosed that comprises passing precursor ions into a drift region or cell such that at least some ions are separated according to their ion mobility, causing at least some of the precursor ions within the drift region or ce...
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WO/2018/026898A1 |
The invention relates to methods and devices for analysis of samples using laser ablation imaging mass cytometry and mass spectrometry. The invention provides methods and devices in which individual ablation plumes are distinctively capt...
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WO/2018/019837A1 |
The invention relates to an analysis device for a gaseous sample, which analysis device comprises a mass spectrometer (6) having a measurement chamber and an inlet (5) leading into the measurement chamber, and a laser irradiation unit (3...
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WO/2018/022482A1 |
A low temperature plasma probe, a mass spectrometry system, and a method for using a low temperature plasma probe are described. In an embodiment, a low temperature plasma probe includes an intake capillary that provides an ion flow from...
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WO/2018/018147A1 |
A method for preparing thin layers from liquid samples is disclosed. Such thin layers can be useful when analyzing samples with probes whose penetration length in these samples is short The method consists of squeezing a certain amount o...
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WO/2018/020363A1 |
A system is disclosed for identifying a precursor ion of a product ion in a scanning DIA experiment. A precursor ion mass selection window is scanned across a precursor ion mass range of interest, producing a series of overlapping window...
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WO/2018/020600A1 |
When carrying out conventional mass spectrometry without ion dissociation, a limited-m/z-range voltage setting unit (52) applies a high-frequency voltage to each rod electrode of a quadrupole mass filter (12) and controls a quadrupole vo...
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WO/2018/020712A1 |
The present invention provides a mass spectrometer, an ion optical device, and a method for ion manipulation in a mass spectrometer. The mass spectrometer comprises a mass analyzer; and further comprises an ion guiding device, including ...
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WO/2018/014140A1 |
Disclosed herein is a method for multimodal imaging during a medical procedure using magnetic resonance imaging (MRI) and Raman optical imaging which involves administering an MRI imaging contrast agent that a chemical structure having c...
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WO/2018/016408A1 |
A mass spectrometer: is provided with a quadrupole electrode system (41) constituted from four rod-shaped electrodes (41a - 41d) disposed parallel to each other on a virtual cylinder, and first and second auxiliary electrode systems (42,...
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WO/2018/011861A1 |
When an optimal collision energy (CE) value corresponding to an MRM transition is to be automatically determined, a tuning-time CE value determination unit (31) determines a plurality of CE values for executing MRM measurement so that th...
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WO/2018/013826A1 |
An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed. An emitter capillary includes an inlet end and an outlet end. A fitting is coupled to the inlet end of the emitter, configured to b...
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WO/2018/007810A1 |
An ion manipulation device is disclosed comprising: an ion receiving region (30) for receiving ions; a pair of electrodes (14,16) adjacent the ion receiving region (30); and an AC or RF voltage supply (18) arranged to apply an AC or RF v...
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