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WO/2010/020812 |
The present disclosure relates to the identification of components in a sample based on the chemical nature of the component. In particular, although not exclusively, the present disclosure relates to the identification of hydrophobic an...
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WO/2010/017499 |
Provided are methods for measuring renin activity in a plasma sample using mass spectrometry. The methods generally involve ionizing purified angiotensin 1 from the sample and detecting the amount of angiotensin 1 ions generated. The amo...
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WO/2010/013824 |
An electrostatic atomizing (1) device includes an atomizing electrode (13) which generates charged fine water particles negatively charged in the form of mist, by generating an electric field when a high negative voltage is applied there...
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WO/2010/013824 |
An electrostatic atomizing (1) device includes an atomizing electrode (13) which generates charged fine water particles negatively charged in the form of mist, by generating an electric field when a high negative voltage is applied there...
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WO/2010/012987 |
A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which ...
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WO/2010/012987 |
A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which ...
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WO/2010/012987 |
A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which ...
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WO/2010/011771 |
An automatic gain control (AGC) technique and apparatus is introduced herein for any temporally non-uniform ion beam, such as, for example, an ion beam produced by a MALDI ion source so as to minimize space charge effects. The disclosed ...
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WO/2010/010333 |
The present invention provides a mass spectrometer including an ion source for generating pre-cursor ions, ion fragmentation means for generating fragment ions from the precursor ions, a reflectron for focusing the kinetic energy distrib...
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WO/2010/010780 |
Provided is a mass spectroscope employing electron capture dissociation wherein the peak number of detectable fragment ions is increased. The mass spectroscope comprises an ion source (2) for generating ions from a sample, an ion trap (3...
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WO/2010/009555 |
A portable plasma based diagnostic apparatus comprising a plasma source for producing energy projectiles at atmospheric pressure, a mass analyzer, a sampling interface for receiving direct sample to be analyzed, the sampling interface be...
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WO/2010/011771 |
An automatic gain control (AGC) technique and apparatus is introduced herein for any temporally non-uniform ion beam, such as, for example, an ion beam produced by a MALDI ion source so as to minimize space charge effects. The disclosed ...
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WO/2010/007373 |
The present invention is concerned with improving the focusing of ions having a particular mass to charge ratio by optimising the electric field for the focusing of ions having that particular mass to charge ratio. In particular, the sti...
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WO/2010/007368 |
An ion source is disclosed wherein a sample is introduced into the sample chamber (1) of the ion source in the gas phase via a sample introduction capillary tube (2). The sample is directed onto a heated surface (6) coated with an oxidis...
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WO/2010/006536 |
An ion mobility spectrometer comprises a sample injector(14), a semipermeable membrane(15), an ionization region(16), a terminal electrode(18), an ion storage region, a migration region and a Faraday plate(22) which are arranged along a ...
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WO/2010/007373 |
The present invention is concerned with improving the focusing of ions having a particular mass to charge ratio by optimising the electric field for the focusing of ions having that particular mass to charge ratio. In particular, the sti...
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WO/2010/002426 |
A system (20) and method utilizes an image analysis approach for controlling the collection instrument-to-surface distance in a sampling system for use, for example, with mass spectrometric detection. Such an approach involves the captur...
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WO/2010/000732 |
The present invention relates to an analytical instrument,and a method for analysing a sample, comprising Secondary Ion Mass Spectrometry (SIMS) means and surface imaging microscopy means.
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WO/2010/002819 |
A chemical processing apparatus includes a fragmentation device that includes a linear set of stacked electrodes and a voltage control module that forms DC potential wells of opposite polarity for mutual confinement of opposite polarity ...
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WO/2010/002427 |
A system (20) and method utilizes distance- measuring equipment (40) including a laser sensor (42) for controlling the collection instrument-to-surface distance during a sample collection process for use, for example, with mass spectrome...
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WO/2009/157312 |
Ions can be analyzed with accuracy and high sensitivity. A first electrode (11) is provided on the outer periphery of a dielectric cylindrical body (13), and a second electrode (12) is disposed in the cylindrical body (13) with a gap fr...
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WO/2009/152945 |
The invention relates to an ion source means comprising at least one holding means for holding at least one sample to expose the sample to a mass spectrometer device, wherein the holding means comprises a structured sample support means ...
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WO/2009/155068 |
An ion detector comprises an ion guide with electrodes arranged about a first axis; a positive ion detection device with an ion inlet at a first side of the ion output section offset from and at an angle to the first axis; and a negative...
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WO/2009/154979 |
A radio frequency (RF) drive system and method for driving the ion trap or mass filter of a mass spectrometer has a programmable RF frequency source coupled to a RF gain stage. The RF gain stage is transformer coupled to a tank circuit f...
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WO/2009/155007 |
A front-end reagent ion source for a mass spectrometer is disclosed. Reagent vapor is supplied to a reagent ionization volume located within a chamber of the mass spectrometer and maintained at a low vacuum pressure. Reagent ions are for...
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WO/2009/152945 |
The invention relates to an ion source means comprising at least one holding means for holding at least one sample to expose the sample to a mass spectrometer device, wherein the holding means comprises a structured sample support means ...
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WO/2009/153841 |
When the isolation of a specific ion is performed and a cleavage operation is performed by use of CID, the ion is captured by applying a high frequency high voltage to a ring electrode (31) as before. The ion is captured by applying the ...
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WO/2009/152945 |
The invention relates to an ion source means comprising at least one holding means for holding at least one sample to expose the sample to a mass spectrometer device, wherein the holding means comprises a structured sample support means ...
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WO/2009/155068 |
An ion detector comprises an ion guide with electrodes arranged about a first axis; a positive ion detection device with an ion inlet at a first side of the ion output section offset from and at an angle to the first axis; and a negative...
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WO/2009/154979 |
A radio frequency (RF) drive system and method for driving the ion trap or mass filter of a mass spectrometer has a programmable RF frequency source coupled to a RF gain stage. The RF gain stage is transformer coupled to a tank circuit f...
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WO/2009/155082 |
Mass spectrometry cells include one or more interleaved magnetostatic and electrostatic lenses. In some examples, the electrostatic lenses are based on electrical potentials applied to magnetostatic lens pole pieces. In other alternative...
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WO/2009/149550 |
A mass spectrometer having an elongated rod set, the rod set having a first end, a second end, a plurality of rods and a central longitudinal axis is described as is a method operating same. Embodiments involve a) admitting ions into the...
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WO/2009/149613 |
An electrode structure used for a mobility tube of a mobility spectrometer comprises ring electrodes. At least a part of two ring surfaces of the ring electrode adjacent to an inner edge are shaped as cones, respectively. Different angle...
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WO/2009/149546 |
A method for operating tandem ion traps is provided, involving a) accumulating ions in the first ion trap at a first time; b) transmitting a first plurality of ions out of the first ion trap and into the second ion trap at a second time,...
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WO/2009/150410 |
A mass spectrometer is provided comprising a first ion trap (2) arranged upstream of an analytical second ion trap (5). The charge capacity of the first ion trap (2) is set at a value such that if all the ions stored within the first ion...
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WO/2009/150410 |
A mass spectrometer is provided comprising a first ion trap (2) arranged upstream of an analytical second ion trap (5). The charge capacity of the first ion trap (2) is set at a value such that if all the ions stored within the first ion...
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WO/2009/149546 |
A method for operating tandem ion traps is provided, involving a) accumulating ions in the first ion trap at a first time; b) transmitting a first plurality of ions out of the first ion trap and into the second ion trap at a second time,...
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WO/2009/152198 |
An ion mobility spectrometer analytical instrument, including an ion mobility spectrometer, a swab interface, and a desorber assembly. The desorber assembly includes a heat transfer device configured to heat a desorber, as well as a supp...
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WO/2009/149124 |
The present invention provides methods for using detection methods, including mass spectrometry methods such as SELDI-TOF-MS, to detect and analyze molecules directly transferred from a sample to a surface to form a molecular print of th...
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WO/2009/147411 |
A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragme...
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WO/2009/148782 |
Auxiliary electrodes for creating drag fields may be provided as arrays of finger electrodes on thin substrates such as printed circuit board material for insertion between main RF electrodes of a multipole. A progressive range of voltag...
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WO/2009/148868 |
A TOF mass spectrometer includes a pulsed ion source that generates a pulse of ions from a sample. An ion lens focuses the pulse of ions into an ion beam. An ion deflector deflects the ion beam. An ion mirror decelerates and then acceler...
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WO/2009/147411 |
A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragme...
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WO/2009/147391 |
A method of operating a gas-filled collision cell in a mass spectrometer is provided. The collision cell has a longitudinal axis. Ions are caused to enter the collision cell. A trapping field is generated within the collision cell so as ...
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WO/2009/147391 |
A method of operating a gas-filled collision cell in a mass spectrometer is provided. The collision cell has a longitudinal axis. Ions are caused to enter the collision cell. A trapping field is generated within the collision cell so as ...
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WO/2009/148868 |
A TOF mass spectrometer includes a pulsed ion source that generates a pulse of ions from a sample. An ion lens focuses the pulse of ions into an ion beam. An ion deflector deflects the ion beam. An ion mirror decelerates and then acceler...
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WO/2009/147411 |
A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragme...
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WO/2009/143623 |
A mass spectrometer system including a differential mobility spectrometer and a mass spectrometer at least partially sealed to, and in fluid communication, with, the differential mobility spectrometer, together with a related method, are...
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WO/2009/146396 |
An Atmospheric Pressure Chemical Ionization (APCI) source interfaced to a mass spectrometer is configured with a corona discharge needle positioned inside the APCI inlet probe assembly Liquid sample flowing into the APCI inlet probe is n...
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WO/2009/144469 |
A method of switching between two modes of power supply to a mass analyser is provided. In a first mode of operation, operated for a first predefined time duration, a first power supply, coupled to the mass analyser, generates a first no...
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