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WO/2012/013354 |
The present invention relates to a method and to a mass spectrometer and uses thereof for detecting ions or subsequently-ionised neutral particles from samples. The method for operating a time-of- flight mass spectrometer for analysis of...
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WO/2012/010894 |
A charged particle spectrum analysis apparatus comprising an electric field generator (11) arranged to subject charged particles to a time- varying electric field, a detector to record charged particle time spectrum data of charged parti...
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WO/2012/012657 |
Sampling substrate analysis inlets, apparatuses, i nstru ments, and methods are provided that can i nclude or utilize one or more of a heated diffuser component, an analyte collection component, and an analyte transfer component.
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WO/2012/007559 |
A mass spectrometer, comprises: a mass analyser with a mass-to-charge dispersive element and arranged to receive ions, to separate the ions according to their mass-to-charge ratios along a dispersive plane and to focus the ions in a beam...
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WO/2012/007267 |
A charged particle energy analyser (10) includes inner and outer cylindrically symmetric electrodes (11,12) arranged coaxially on a longitudinal axis (z-z) of the analyser. A position-sensitive detector (17) has a particle-receiving dete...
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WO/2012/003739 |
An ion mobility tube includes an ionization source room (1) having a central ionization source room hole, an ion door (2), a drift region unit (3) having a central drift chamber, a restraining grid (4), and a Faraday disk (5), which are ...
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WO/2012/003946 |
A laser-ablation ion source is provided for generating a low energy ion beam having low longitudinal and transverse emittance. The ion source comprises a supersonic nozzle ( 13), followed by an RF ion funnel (23). A laser source (41) gen...
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WO/2012/004613 |
A capacitor assembly (1) for measuring the level of radio frequency voltage in a mass spectrometer. The assembly (1) includes an RF sensing capacitor (2) with first and second capacitor plates (3, 4), a rectifying circuit (5) and a vacuu...
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WO/2012/005561 |
The invention relates to an electronic analytical technique for determining the composition and structure of substances and, more specifically, to the field of analyzers comprising at least one mass spectrometer, and can be used in medic...
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WO/2012/001421 |
The invention relates to systems employing microdroplets, in embodiments for Microdroplet Electrospray Ionisation Mass Spectrometry (ESI MS). Thus in one aspect we describe a method of detecting an analyte, the method comprising: providi...
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WO/2011/160990 |
The invention relates to an apparatus (20) for structuring solid surfaces (18) using ion beams (141) from an ion beam spectrum (14), wherein the ion beam spectrum (14) has ions having different charge states and different masses. The app...
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WO/2011/161788 |
Inside a first-stage intermediate vacuum chamber (6) of an atmospheric-pressure ionization mass-spectrograph apparatus, cluster ions that are the cause of background noise are generated mainly at area (A), and fragment ions are generated...
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WO/2011/157781 |
The invention relates to a method of ion mobility spectrometry (IMS), in particular a corresponding method for determining the analytes. It is the object of the invention to develop a method with which IMS spectra, recorded under varying...
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WO/2011/156864 |
The invention provides an element (12), comprising: a nanoporous insulating film (20) (such as a thin nanoporous diamond film) and first and second conducting layers (18a, 18b) on first and second opposed sides respectively of the film (...
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WO/2011/154731 |
A mass spectrometer ts disclosed comprising a RF confinement device (6), a beam expander (7,9) and a Time of Fight mass analyser. The beam expander (7,9) is arranged to expand an ion beam emerging from the RF confinement device (6) so th...
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WO/2011/154219 |
A method, computer program and system to identify peaks generated by different physical ions in a solution including substances by analyzing mass and intensity coordinates of all peaks in a set of mass spectra measured with errors for a ...
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WO/2011/156499 |
Methods and devices for mass spectrometry are described, specifically the use of nanoparticulate implantation as a matrix for secondary ion and more generally secondary particles. A photon beam source or a nanoparticulate beam source can...
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WO/2011/147804 |
Methods and analyzers useful for time of flight mass spectrometry are provided. A method of determining properties of ions within a time of flight or electrostatic trap mass analyzer comprises the steps of: injecting ions into the mass a...
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WO/2011/148312 |
A mass spectrometer comprises ion pulse means for producing ion pulses in a first vacuum chamber, ion trap means for receiving and trapping the ion pulses for mass analysis in a second vacuum chamber, and ion-optical lens means arranged ...
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WO/2011/144743 |
A sample support plate (100) for a variety of possible applications, including MALDI mass spectrometry, is disclosed. A plurality of spatially separated sample recipient sites (101) are arranged on the surface of a substrate. The recipie...
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WO/2011/146737 |
A mass spectrometer system and a method of operating same are provided. The system comprises a) an ion conduit for receiving ions; b) a boundary member defining a curtain gas chamber containing the ion conduit; c) a curtain gas supply fo...
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WO/2011/146269 |
Described are techniques for tuning parameters of a system. For one or more values of a distance, mass spectral analysis of a liquid analyte stream is performed. A corresponding ion signal intensity of a selected ion is obtained. The dis...
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WO/2011/145923 |
The invention provides an apparatus for sequentially analyzing a plurality of samples containing electrochemically active substances, said apparatus comprising: a sample conduit (10); an electrochemical flow cell (20); a source of carrie...
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WO/2011/140636 |
An ion lens for reducing contaminant effects in an ion guide of a mass spectrometer is provided. The ion lens comprises a structural member comprising an orifice of a given radius, the structural member for supporting the ion lens at an ...
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WO/2011/141826 |
The chemical composition of petroleum samples is measured using orbitrap mass spectrometry with electrospray ionization (ESI). The orbitrap measurement is used in a screening to determine if one or more higher resolution (but more expens...
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WO/2011/140492 |
A system and method is disclosed for extracting a sample from a sample surface. A sample is provided and a sample surface receives the sample which is deposited on the sample surface. A hydrophobic material is applied to the sample surfa...
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WO/2011/139274 |
According to certain embodiments, a method of mass spectrometry may generally comprise subjecting a sample comprising at least one indicator to laser ablation electrospray ionization mass spectrometry; determining a relative intensity of...
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WO/2011/138669 |
There is provided a pulser, a time of flight mass spectrometer system comprising the same, and a method of analyzing the ions using the pulser. The pulser comprises a first positive switch for coupling and decoupling a first electrode of...
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WO/2011/137533 |
Methods are provided for the preparation of a sample using a digital microfluidic platform and the optional subsequent mass analysis of an extracted analyte. A sample is dried, optionally on a solid phase support, and contacted with digi...
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WO/2011/138669 |
There is provided a pulser, a time of flight mass spectrometer system comprising the same, and a method of analyzing the ions using the pulser. The pulser comprises a first positive switch for coupling and decoupling a first electrode of...
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WO/2011/140492 |
A system and method is disclosed for extracting a sample from a sample surface. A sample is provided and a sample surface receives the sample which is deposited on the sample surface. A hydrophobic material is applied to the sample surfa...
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WO/2011/139909 |
An electromagnetic field generator includes a semiconductive material shaped to form a complex electromagnetic field including a magnetic field and an electric field. An instrument includes a passage configured such that charged particle...
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WO/2011/140116 |
A method of calibrating ion collision energy used in a mass spectrometer, wherein said method includes a step of obtaining fragment ion, yield data for each of a plurality' of precursor ion populations having respective mass-to-charge ra...
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WO/2011/134968 |
The invention relates to a method and an apparatus for evaporating at least a portion of a liquid (3), characterized in that the liquid is conducted through a duct (5) past an opening (4) leading into a vapor chamber (9) which is kept at...
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WO/2011/135477 |
A method, apparatus and algorithms are disclosed for operating an open electrostatic trap (E-trap) or a multi-pass TOF mass spectrometer with an extended flight path. A string of start pulses with non equal time intervals is employed for...
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WO/2011/131142 |
A method for generating and analyzing ions directly without pretreatment and an apparatus thereof are provided. In the method, gaseous neutral molecules are generated at atmospheric pressure; then the generated neutral molecules are tran...
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WO/2011/133817 |
An ion transfer tube having an ion inlet and an ion outlet is characterized by: a first tube member comprising an electrically resistive material and having a first end comprising the ion inlet and a second end; a first electrode electri...
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WO/2011/128702 |
A method and system for the identification and/or characterisation of properties of a sample using mass spectrometry. The method involves producing a measured spectrum of data from a sample using a mass spectrometer, deconvoluting the me...
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WO/2011/128600 |
The present invention relates to a device for measuring glow discharge spectrometry in pulsed mode, which includes an RF electric field generator in pulsed mode, a discharge lamp, an impedance tuner for transferring the electric power su...
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WO/2011/128040 |
A mass spectrometry system based on the general principle of accelerator mass spectrometry (AMS) is disclosed. An ion source (10) generates a beam (B) of ions having a negative charge state. A first mass analyzer (20) transmits only ions...
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WO/2011/130544 |
The present invention provides a method for monitoring of profile changes of components in a dynamic system such as a cell-free in vitro protein synthesis system by using liquid chromatography (LC) combined with mass spectrometry (MS). I...
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WO/2011/127322 |
Methods and compositions related to high mannose glycans are described.
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WO/2011/125399 |
Disclosed is a quadrupolar mass analysis device provided with direct-current voltage sources (62, 63) having response characteristics wherein the response time of the direct-current voltage is shorter than the time required when an ion h...
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WO/2011/127091 |
Novel methods and instrumentation for mass spectrometry are described. Zoom-time of flight mass spectrometry (Zoom-TOF) allows increased mass resolution over a pre-determined specific range of masses. Methods for retrofitting traditional...
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WO/2011/125218 |
Disclosed is a quadrupolar mass analysis device provided with direct-current voltage sources (62, 63) having response characteristics wherein the response time of the direct-current voltage is shorter than the time required when an ion h...
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WO/2011/126584 |
A new pulsed multiple reaction monitoring process and system are disclosed that uses a pulsed ion injection mode for use in conjunction with triple-quadrupole instruments. The pulsed injection mode approach reduces background ion noise a...
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WO/2011/123667 |
A touch screen user interface 24 for an optical device wherein the touch screen user interface 24 is connected to a controller 22 which controls motion stages 26 permitting the motion stages 26 to re-position, re-size, re-orient or focus...
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WO/2011/122687 |
A liquid metal ion source 10 consists of a needle electrode 11 which is made from two metal wires 11a and 11b arranged in parallel with their outer surfaces being in contact with each other. The needle electrode 11 has a guide passage 11...
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WO/2011/123664 |
An improved sample chamber 40 for laser assisted spectroscopy integrates valve mechanisms 48, 58 into the sample drawer 46, permitting the sample chamber 40 to automatically bypass, purge and resume flow as the sample drawer 40 is opened...
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WO/2011/121302 |
A charged particle analyser analyses charged particles having a range of energies. A charged particle source directs charged particles into a magnetic focusing field. A detector detects charged particles focussed by the magnetic focusing...
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