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Matches 1 - 50 out of 16,039

Document Document Title
WO/2018/007810A1
An ion manipulation device is disclosed comprising: an ion receiving region (30) for receiving ions; a pair of electrodes (14,16) adjacent the ion receiving region (30); and an AC or RF voltage supply (18) arranged to apply an AC or RF v...  
WO/2018/007394A1
The present invention relates to a method for providing a calibrated result of a determination of at least one analyte of interest in a biological sample comprising a) providing a matrix calibration sample, wherein the concentration of a...  
WO/2018/005948A1
The present disclosure generally relates to methods for determining chemical class compositions present in a sample using collision cross-section fragment ion values.  
WO/2018/005918A1
An ion transfer system includes an ion source coupled to an ion inlet; an ion transfer tube assembly including a concentric ion transfer tube with a porous material that is permeable to a gas, the concentric ion transfer tube coupled to ...  
WO/2018/004769A2
The invention generally relates to systems and methods for collision induced dissociation of ions in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central pro...  
WO/2018/005679A1
A system and method for performing field-portable GC/MS measurements for the rapid sampling and measurement of high temperature boiling semi-volatile organic compounds in environmental samples, wherein other column bundles have cold spot...  
WO/2018/003465A1
The present invention provides a signal processing method, a signal processing system and an electronic apparatus for analysis of time- of-flight mass spectra. The method comprises: (a) digitalizing an analog signal output from an ion de...  
WO/2017/221151A1
Methods and systems are provided herein for selectively removing product ions resulting from an ECD dissociation event from the interaction region of an ECD reaction cell, while other precursor peptide ions continue to undergo ECD within...  
WO/2017/216692A1
Systems and methods are disclosed for determining if the dynamic range of quantitation in mass spectrometry can be extended. A DIA method is performed on a sample for a compound of interest at each acquisition time of a plurality of acqu...  
WO/2017/214037A1
The present disclosure relates to novel and improved methods of analyzing proteins, peptides and polypeptides by mass spectrometry using ion-ion reactions. More specifically the disclosure relates to improved methods for implementing the...  
WO/2017/214177A1
Disclosed herein are devices and methods for detecting compounds in droplets using mass spectrometry. In some embodiments, the device comprises: a microfluidics-MS (microMS) device, wherein the microMS device comprises: a droplet-to-digi...  
WO/2017/211627A1
The invention relates to a device and to a method for generating, storing, and liberating ions from a residual gas atmosphere, comprising an electron source for liberating electrons, an anode that is permeable to the electrons liberated ...  
WO/2017/212248A1
A method of analysing a target is disclosed comprising ablating a portion of a target so as to cause an aerosol plume to be produced and light or other electromagnetic radiation to be emitted. The aerosol plume is analysed using mass spe...  
WO/2017/206965A1
An analysis method for a quadrupole rod mass analyzer, which belongs to the field of mass analysis. In the method, a higher quadrupole mass spectrum mass distinguishing capability is implemented by using a working voltage technology load...  
WO/2017/210635A1
The invention provides general methods for data acquisition and analysis of any small organic or biological molecule in mass spectrometric assays. The methods include acquiring overlapping precursor isolation windows combined with a deco...  
WO/2017/208030A1
There is provided an apparatus comprising a first ion source (10) arranged and adapted to emit a spray of charged droplets (11), and a control system arranged and adapted to control one or more spatial properties of said spray of charged...  
WO/2017/210557A1
Components resolved in time by a thermal desorption separator accumulate in a sample cell and are analyzed by electromagnetic radiation-based spectroscopic techniques.  
WO/2017/208025A1
A method of analysing a sample is disclosed that comprises surveying a sample in a first mode of operation by directing a spray of charged droplets onto the sample, determining one or more regions of interest in the sample, and analysing...  
WO/2017/210560A1
Systems, methods, and devices to dissociate ions using one or more light emitting diodes (LEDs). A mass spectrometer for ion dissociation includes an ion source for providing ions for dissociation, a mass analyzer, and a photodissociatio...  
WO/2017/208026A1
Apparatus is disclosed comprising a first ion source (210) arranged and adapted to emit a spray of charged droplets (211) and a detector or sensor (203) arranged and adapted automatically to detect, sense or determine one or more first p...  
WO/2017/208417A1
In a mass spectrometer system, the tip part of a cylinder part (891) of a capillary (89), which is a spray part by which a sample solution is sprayed on an ionizing part, is coated by a coating material (892). Thus, by using the coating ...  
WO/2017/205516A1
Electrospray devices are described. The devices may comprise a substrate and a plurality of emitters. The emitters may comprise a plurality of channels therein, wherein the channels may be configured to convey immiscible liquids to the d...  
WO/2017/202561A1
An apparatus and method for extracting mass information from low resolution mass-to-charge ratio spectra of multiply charged species is described. Curve fitting is performed using the logarithm of the mass to charge data, which deemphasi...  
WO/2017/204916A1
Method and apparatus for generating asymmetric high-voltage waveforms with near- rectangular profiles. The method comprises producing selected low-frequency components of the Fourier series for a rectangular waveform explicitly and addin...  
WO/2017/205694A1
The present invention provides a method of making an antibody by identifying a circulating antibody with activity from a subject comprising i) subjecting biological fluid selected from the group consisting of blood, plasma and serum and ...  
WO/2017/200695A1
Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially acco...  
WO/2017/196863A1
A device for detecting charged particles includes a substrate, a charge detection plate and an integrated circuit unit that are electrically connected together and respectively disposed on non-coplanar first and second sides of the subst...  
WO/2017/193213A1
Disclosed herein is a system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device. The system includes a desorption chamber sized to accept the SPME device while defining a void volume of less than...  
WO/2017/194972A1
An ambient ionisation ion source is disclosed that comprises a first device arranged and adapted to generate analyte ions from a target and an enclosure surrounding the first device. The enclosure includes one or more gas inlets and one ...  
WO/2017/194974A1
Disclosed herein is an ion guide comprising a plurality of axially stacked plates, wherein at least some or all of said plates comprise: a first electrically conductive portion; and a second electrically conductive portion, wherein the s...  
WO/2017/194333A1
The invention relates to an apparatus (1) for detecting ions (4a, 4b), comprising: an ion trap (2) having a first electrode, preferably a ring electrode (3) and also having at least one second electrode, preferably a cap electrode (7a, 7...  
WO/2017/196434A1
An electron spectroscopy system (1 1;201 ) and method are disclosed. In another aspect, an ultrabright and ultrafast angle-resolved electron spectroscopy system is provided. A further aspect of the present system employs an electron gun ...  
WO/2017/192413A1
Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as alpha-ketoglutarate.  
WO/2017/187880A1
An ion optical device of the present invention comprises one or more pairs of confinement electrode units arranged opposite to each other at two sides of a first direction in a space and extending along the first direction; a power suppl...  
WO/2017/182404A1
The present application describes a method for sequencing oligosaccharides, which enables the primary sequence of an oligosaccharide with unknown structure to be identified, including the composition of same in monosaccharides, the posit...  
WO/2017/182794A1
Disclosed herein is a method comprising liberating analyte material from a sample and transferring the liberated analyte material towards an inlet of an ion analyser via a sampling or transfer tube (202). The presence of the analyte mate...  
WO/2017/184944A1
An ion transfer tube assembly, a mass spectrometry system, and a method for providing an ion stream to an ion detection device are described that include using an ion transfer tube that provides a coaxial sheath gas flow. In an implement...  
WO/2017/183086A1
An image formation optical system (15) having a small focal distance and an aperture member (14) having an opening having a predetermined shape are disposed in a predetermined position between a laser irradiation part (13) and a sample (...  
WO/2017/181030A2
Methods and apparatus for detection and/or identification of analytes including bacteria using dielectrophoresis and electroosmotic traps. Switching between different frequencies of an applied electric field results in movement of the an...  
WO/2017/180871A1
The invention generally relates to systems and methods for isolating a target ion in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CP...  
WO/2017/178453A1
A method and an apparatus for determining a concentration of a target analyte in a sample of bodily fluid are disclosed. The method comprises providing a sample of bodily fluid including the target analyte, providing an internal standard...  
WO/2017/180939A1
The present disclosure relates generally to rapid authentication methods using surface desorption ionization and mass spectrometry detection. In particular, the disclosure relates to rapid methods of authentication of commercial or consu...  
WO/2017/178835A1
A method of mass spectrometry is disclosed comprising: performing a plurality of cycles of operation during a single experimental run, wherein each cycle comprises: mass selectively transmitting precursor ions of a single mass, or range ...  
WO/2017/178672A1
A method for obtaining the absorption position, mass and rigidity of a particle deposited on the surface of a resonator based on the relative change in the resonance frequency of said resonator in 3 or 4 flexural vibration modes. The rig...  
WO/2017/176423A1
A method of generating a classifier includes a step of classifying each member of a development set of samples with a class label in a binary classification scheme with a first classifier; and generating a second classifier using a class...  
WO/2017/176946A1
Systems and methods for targeted therapy based on single-cell stimulus perturbation response. In one embodiment, a method for optimizing stimulus combinations for therapy includes receiving a cell sample, treating the cell sample with a ...  
WO/2017/173365A1
Provided herein are methods, chemical library and simulation system for performing in situ patterned chemistry. Methods, systems and assays comprising the use of the synthesized chemical libraries, which increase explored protein space i...  
WO/2017/171176A1
A mass spectrometer using near infrared (NIR) fluorescence can comprise: a plate formed such that a sample, which includes a matrix for ionization and a fluorescent material having an excitation wavelength of an NIR wavelength band, is l...  
WO/2017/168282A1
An apparatus includes a first electrode and a second electrode. The second electrode is placed in parallel with the first electrode to provide constant gap distance. The gap between the first electrode and the second electrode is at atmo...  
WO/2017/168389A1
A data acquisition system for acquiring a digitized time-domain signal and corresponding mass spectra from a mass spectrometer. The system comprises a signal conditioning device including an amplifier and an analog low-pass filter, to am...  

Matches 1 - 50 out of 16,039