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Matches 1 - 50 out of 16,895

Document Document Title
WO/2019/215428A1
A mass spectrometer comprising: a multi-reflecting time of flight (MRTOF) mass analyser or mass separator having two gridless ion mirrors 2 that are elongated in a first dimension (Z-dimension) and configured to reflect ions multiple tim...  
WO/2019/215910A1
In the present invention, a mass spectrum data acquisition processing unit (21) acquires mass spectrum data by ionizing an unknown sample and standard sample and simultaneously subjecting the same to mass spectrometry. A data correction ...  
WO/2019/214885A1
The invention relates to a device and a corresponding method for mass spectroscopic analysis of particles, the device comprising: a first irradiation unit (4) configured to irradiate a particle (1) with electromagnetic radiation to cause...  
WO/2019/217541A1
An ion source includes a base, a first chamber, a second chamber and an extractor. The first chamber is disposed downstream of the base and defines a first internal volume having a first pressure. The second chamber is disposed downstrea...  
WO/2019/215429A1
A mass spectrometer comprising: an ion energy filter 14 arranged and configured to filter ions according to their kinetic energy and so as to only transmit ions having a component of kinetic energy in a first dimension (z-dimension) that...  
WO/2019/213697A1
The present invention relates generally to components of scientific analytical equipment. More particularly, but not exclusively, the invention relates to electron multipliers and modifications thereto for extending the operational lifet...  
WO/2019/214863A1
The invention relates to a method for producing an atom trap (20), having the steps of: (a) applying an electrically conductive starting layer (2) onto a substrate (1), (b) applying at least one electric conductor element (4) onto the st...  
WO/2019/217858A1
The disclosure describes various aspects of a cryogenic trapped-ion system. In an aspect, a method is described that includes bringing a chain of ions in a trap at a cryogenic temperature, the trap being a micro-fabricated trap, and perf...  
WO/2019/213130A2
A low power mass spectrometer assembly includes at least an ionization component, an electrostatic analyzer, a lens assembly, a magnet assembly and at least one detector located in a same plane as the entrance to the magnet assembly for ...  
WO/2019/211597A1
A detection device, preferably an ion-mobility spectrometer (IMS) comprising: a substance detector for detecting the presence of a substance of interest in a vapour; an inlet passage for receiving vapour desorbed from a sample, and provi...  
WO/2019/213480A1
The structures of very long chain dicarboxylic acids from blood samples may be validated through chemical derivatization of the dicarboxylic functionality with 2-picolomine before positive ESI mass spectroscopy analysis. Laboratory stand...  
WO/2019/211788A1
An ionizer includes a probe having multiple coaxially aligned conduits. The conduits may carry liquids, and nebulìzing and heating gases at various flow rates and temperatures, for generation of ions from a liquid source. An outermost c...  
WO/2019/211886A1
According to the present invention, during MS/MS analysis, a collision energy (CE) greater than that for ordinary MS analysis is imparted to ions which are then introduced into a collision cell (13) where the ions are dissociated. Then, ...  
WO/2019/213133A1
Systems and methods are configured to detect and/or ablate cancerous tissue, such as during surgery. The system uses Laser Ramen Spectroscopy (LRS) or Surface Enhanced Raman Spectroscopy (SERS) to enhance a detection signal pursuant to a...  
WO/2019/211918A1
According to the present invention, when a user specifies, via an input unit (54), a mass range of a mass spectrum desired for observation, a CES analysis control unit (51) controls respective components so that MS/MS analysis is conduct...  
WO/2019/207737A1
During automatic adjustment of a detector voltage, a reflection voltage generator (33) under the control of an auto-tuning controller (42) applies a voltage different from a normal measurement voltage at which ions are not temporally foc...  
WO/2019/208328A1
This electron capture detector (100) is a device for detecting a sample (α1). The electron capture detector (100) comprises a detection cell (1), sample introduction part (2), and electron emission element (20). A reaction chamber (6) i...  
WO/2019/210233A1
Embodiments of the present invention relate to reagents and their use for elemental imaging mass spectrometry of biological samples. The embodiments comprising methods for quantifying one or more analytes within a sample, comprising the ...  
WO/2019/205805A1
The present invention provides a sample desorption and ionization device, and a mass spectrometer and an analysis method. The device comprises: a heating desorption device, located in a first gas pressure region, and used for bearing and...  
WO/2019/206952A1
The invention provides a secondary ion mass spectrometer comprising a primary ion beam device, and means for collecting, mass filtering and subsequently detecting secondary ions released from a sample due to the sample having been impact...  
WO/2019/202719A1
An inductively coupled plasma mass spectrometer 1, provided with: an ionization unit 10 for ionizing a sample by a plasma generated from raw material gas; a vacuum chamber separated into a first space 21 kept at a first pressure lower th...  
WO/2019/202518A1
Certain configurations of a mass analyzer comprising two chambers for ionizing species to form ions and/or introduce a reaction gas to assist in ionization are described. In some instances, a first chamber may receive electrons to permit...  
WO/2019/202338A1
An ion mirror 41constructed of thin electrodes that are interconnected by resistive dividers45 with potentials U1-U5 applied to knot electrodes to form segments 41-43 of linear potential distribution between the "knot" electrodes, yet wi...  
WO/2019/200262A1
The present disclosure provides methods for the rapid synthesis of large libraries of spherical nucleid acid (SNA) nanoparticles, their screening for activity, and a machine learning algorithm to analyze the data.  
WO/2019/200388A1
Techniques and apparatus for ion source devices with minimized post- column volumes are described. In one embodiment, for example, an ion source assembly (330) may include a chromatography column (334) in fluid communication with an ion ...  
WO/2019/197258A1
A method of operating a mass spectrometer vacuum interface, the vacuum interface comprising an evacuated expansion chamber downstream of a plasma ion source at atmospheric or relatively high pressure, the expansion chamber having a first...  
WO/2018/183448A8
A method for determining in a sample, by mass spectrometry, the presence, absence or amount of one or more lipid species from one or more lipid classes is described herein. The one or more lipid classes are selected from the group consis...  
WO/2019/160739A3
Provided herein are methods and systems for biochemical analysis, including compositions and methods for processing and analysis of small cell populations and biological samples (e.g., a robotically controlled chip-based nanodroplet plat...  
WO/2019/198010A1
Systems and methods are disclosed for dynamically switching an ion guide and a TOF mass analyzer between concentrating or not concentrating ions in a targeted acquisition. Product ions are ejected from the ion guide into the TOF mass ana...  
WO/2019/195896A1
The present invention relates to generally to components of scientific analytical equipment. More particularly, the invention relates to instruments such as mass spectrometers that rely on ion detectors and modifications thereto for exte...  
WO/2019/197880A1
A prefabricated polymeric layer (300) to be used in a matrix-assisted laser desorption/ionization (MALDI) based system (400), the prefabricated polymeric layer (300) including a first sublayer (302); and a second sublayer (304) attached ...  
WO/2019/193926A1
In the mass spectrometer, which comprises an ionization unit, a sample that has been separated in a separation column is ionized by the ionization unit and is thereafter subjected to mass separation, and ions obtained by said mass separa...  
WO/2019/193791A1
This vacuum device is provided with a first chamber, a second chamber connected with the first chamber via an opening part, and a depressurizing part that depressurizes the first chamber and the second chamber. The first chamber is provi...  
WO/2019/193191A1
Disclosed herein is an ion guide (42) for guiding an ion beam along an ion path, said ion guide having a centerline (46) corresponding to said ion path, and a plurality of electrodes extending along said centerline. The electrodes are fo...  
WO/2019/193170A1
Disclosed herein is an ion guide (32) for guiding an ion beam along an ion path, said ion guide (32) having a longitudinal axis (48) which corresponds to said ion path. Said ion guide (32) comprises a plurality of electrode plates (44) w...  
WO/2019/193171A1
Disclosed herein is an ion guide (36) for guiding an ion beam along an ion path, said ion guide (36) having a longitudinal axis (44) corresponding to said ion path, said ion guide (36) comprising a plurality of elongate electrodes arrang...  
WO/2019/187352A1
In this mass spectrometer, a first chamber and a second chamber communicate via an opening. When a closing part 34 moves toward an opening 51 due to the actions of a first displacement mechanism and a second displacement mechanism, a con...  
WO/2019/122358A3
A method of ionizing a sample is disclosed that comprises heating a sample so that analyte is released from the sample, producing charged particles such as charged droplets downstream of the sample, and using the charged particles to ion...  
WO/2019/187431A1
A positive high voltage, a first terminal of a semiconductor element, and a first terminal of a first resistance element are connected to a first terminal of a first current controller. A current input terminal of a first active element ...  
WO/2019/187353A1
This MALDI ion source 1 has a lens 6 that is provided between a mirror 7 and a sample on a sample plate 111. In the MALDI ion source 1, the optical axis of a laser beam coming into a chamber 3 from a laser light source 2 is located coaxi...  
WO/2019/187048A1
This mass spectrometry device (1) is equipped with a mass spectrometry unit (2). The mass spectrometry unit (2) is installed in a horizontal orientation. As such, if the mass spectrometry unit (2) is adapted to have many components, the ...  
WO/2019/169163A9
MALDI-MS operated slightly under matrix storm conditions with a high- energy -transfer, acidic matrix, or these conditions with a high sample to matrix ratio, can with ultrasensitivity detect a nucleobase, modified or canonical, of a nuc...  
WO/2019/187408A1
After a sample solution is converted into a sample mist by a nebuliser (4), solvent is removed by heating with a solvent removal unit (7). A sample gas comprising the sample mist following solvent removal and a carrier gas is introduced ...  
WO/2019/181970A1
An organic silica thin film comprising: organic silica having a light absorbable organic group in a skeleton, wherein the organic group has a local maximum absorption wavelength in a wavelength range of 200 to 1200 nm, a content ratio of...  
WO/2019/178649A1
The present invention relates to generally to components of scientific analytical equipment. More particularly, the invention relates to ion detectors of the type which incorporate electron multipliers and modifications thereto for exten...  
WO/2019/180045A1
An isotope ratio mass spectrometer (100) has an ion source (15), a static field mass filter (120), a reaction cell (30) to induce a mass shift reaction, and a sector field mass analyser (41, 42, 43) for spatially separating ions from the...  
WO/2019/182962A1
The invention generally relates to logical operations in mass spectrometry. The system comprising a mass spectrometer comprising one or more ion traps; and a central processing unit (CPU), and storage coupled to the CPU for storing instr...  
WO/2019/175568A1
A method of analysing a structure of a composition of matter in a sample comprising: a) obtaining a plurality of tandem mass spectra derived from a first parent ion of a first m p /Z p ; b) dividing each spectra into a plurality of m/z b...  
WO/2019/175478A1
The disclosure of the embodiments concern a method of detecting hydrogen halides HX. Embodied method comprises sampling (301) a gas sample into a sample flow via a sampling port of the detection arrangement for detecting hydrogen halides...  
WO/2019/147748A3
A surface ionizer for a trace detection system includes an extreme ultraviolet light source and an ion transfer line. Activation of the extreme ultraviolet light disrupts a surface of a sample along with residue and ionizes the resulting...  

Matches 1 - 50 out of 16,895