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Document	Document Title
7311759	Process for purifying off-gases of a melamine plant A two-stage process is provided for purifying off-gases from a high-pressure melamine plant. In the first stage, the off-gases are contacted with a recirculated urea melt containing melamine precursors and NH 3 . In the second stage, the...
6600970	Method of establishing synthesis paths A method of establishing a synthesis path in a multiplicity of potentially interlinakable reactions, and a computer program to prepare a synthesis path.
6515192	Hyperbranched compounds with a tetrafunctional central group and use of same Hyperbranched compounds having a tetrafunctional central group of the general formula I C[—A q —X—] m [—A r —X—] n [—A s —X—] o [—A t —X—] p (I), in which the indices and variables have the following meanings: ...
6248265	Clean generation of a fluoroaryl grignard reagent Fluoroaryl Grignard reagents are produced from a hydrocarbyl Grignard reagent and fluoroaromatic compounds via separate additions of different fluoroaromatic compounds, such that the conversion of hydrocarbyl Grignard reagent to the desi...
5463564	System and method of automatically generating chemical compounds with desired properties A computer based, iterative process for generating chemical entities with defined physical, chemical and/or bioactive properties. During each iteration of the process, (1) a directed diversity chemical library is robotically generated in...
4793980	Hollow porous microspheres as substrates and containers for catalyst Hollow porous microspheres are used as substrates and containers for catalyst to make microsphere catalysts. The hollow porous microspheres are made from dispersed particle compositions. The microspheres have a single central cavity, hav...
4638081	Process for preparing α-aspartyl-L-phenylalanine methyl ester A process for preparing α-L-aspartyl-L-phenylalanine methyl ester consisting of: bringing N-formyl-L-aspartic anhydride and L-phenylalanine methyl ester, in a molar ratio equal or approximately equal to 1:1, into contact with a solid ca...
4629695	Peptide derivatives and use thereof as substrates for quantitatively assaying enzymes Peptide derivatives of formula ##STR1## wherein R 1 represents a substituted amino group which is capable of being split off enzymatically with formation of a colored or fluorescent compound R 1 -H. The said peptide derivatives are use...
4626525	Antibiotics, preparation and use of and intermediates therefor New antibiotics of the formula ##STR1## in which X is O or N--CO--NH 2 , R is the radical of an aminoacid other than serine, an oligopeptide other than HyoHyoHyoSer or a derivative thereof on the free amino group, or a radical from th...
4622418	L-aminodicarboxylic acid amides Amides of α-aminodicarboxylic acids and β-aminoethers are low calorie sweetners.
4622417	L-aminodicarboxylic-(O-cycloalkyl)-L-aminocarboxylate alkyl ester sweeteners Dipeptides of certain α-amino dicarboxylic acids and etherified hydroxy α-amino-mono-carboxylic acid esters possess a high order of sweetness. These dipeptides have the following formula: ##STR1## wherein R is alkyl containing 1-3 carb...
4618695	Method of preparing methyl ester and its hydrochloride A method of preparing α-L-phenylalanine methyl ester and its hydrochloride, which comprises dissolving α-L-aspartyl-L-phenylalanine β-methyl ester in a methanol/hydrochloric acid mixture solvent which contains, when hydrochloric acid ...
4610818	N-acyl derivatives of dipeptides, their preparation and their use in the therapy of disorders, and agents for this purpose N-acyl derivatives of dipeptides of the formula X-CO-L-Leu-NH-CH 2 -CO-R where X and R have the meanings given in the description, are useful for the therapy of disorders.
4610817	N-acyl derivatives of peptides, their preparation and their use in the treatment of disorders, and agents for this purpose Novel N-acyl derivatives of peptides related to L-pro-L-leu-gly-NH 2 , melanocyte stimulating hormone-release inhibiting factor (MIF), and therapeutic compositions which are useful for the treatment of depression.
4609641	Renin-inhibitory peptide analogs Peptides having the formula ##STR1## and their use as pharmaceuticals are disclosed.
4609496	Steroid esters of N-(2-halogenoethyl)-N-nitroso-carbamoyl-amino acids and peptides thereof, as well as methods for preparing them Steroid-N-(2-halogen ethyl)-N-nitroso-carbamoyl-amino acid or peptide esters of the general formula: ##STR1## where R 1 and R 2 , which may be identical or different, mean the radical of an amino acid beyond the C atom in the beta posit...
4606857	Muramyldipeptide derivatives Muramyldipeptide derivatives represented by the formula: ##STR1## wherein Ala represents alanine; Acyl represents an acyl group; R 1 and R 2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R 3 re...
4603012	L-aminodicarboxylic acid alkanes This invention relates to novel sweeteners of the formula: ##STR1## wherein A is hydrogen, alkyl containing 1-3 carbon atoms, hydroxyalkyl containing 1-3 carbon atoms, alkoxymethyl wherein the alkoxy contains 1-3 carbon atoms or --CO 2 ...
4603011	L-aminodicarboxylic acid amides of alkoxyalkylamines The present invention is directed to new sweeteners of the formula: ##STR1## wherein, A is H, alkyl containing 1-3 carbon atoms, hydroxyalkyl containing 1-3 carbon atoms, alkoxymethyl wherein the alkoxy group contains 1-3 carbon atoms, o...
4599325	Substituted tyrosyl alanine dipeptide amides The invention relates to novel substituted tyrosyl alanine dipeptide amides of the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof wherein R 1 represents straight or branched lower alkyl having 1 to 4 c...
4584285	Antihypertensive agents (Benzothiadiazine, benzamido and benzenesulfonyl)phenyl-substituted carboxyalkyl dipeptide compounds are disclosed. Compounds of this invention are useful as antihypertensive agents.
4579841	Dipeptide derivatives having opiate activity A class of dipeptide derivatives having opiate activity having the formula Tyrosyl--X--Y wherein X is a D- or L-amino acid radical and Y is an amide or substituted amide are disclosed.
4569793	Cyanohydrination catalyst A cyanohydrination catalyst for the preparation of alpha-hydroxynitriles from aldehydes and ketones comprises a solid cyclo(D-phenylalanyl-D-histidine) or cyclo(L-phenylalanyl-L-histidine) dipeptide having a non-crystalline or amorphous ...
4568666	Carboxylalkyl peptide derivatives This invention encompasses novel carboxyalkyl peptide derivatives which are collagenase inhibitors.
4568489	N-Acyl-γ-glutamyl imino and amino acids and esters Compounds of the formula ##STR1## wherein X is various imino or amino acids or esters are disclosed. These compounds possess angiotensin converting enzyme inhibition activity and depending upon the definition of X also possess enkephalin...
4564471	Method for reductive elimination of protecting groups The invention provides a novel and efficient method for the elimination of protecting groups, e.g. benzyloxycarbonyl group, from a protected amino acid, peptide or derivative thereof having at least one functional group protected by a pr...
4563305	Radiolabelled substrates for assaying mammalian enzymes Compounds which are substrates for mammalian enzymes, especially proteolytic and peptidase enzymes, are disclosed. These compounds, in general, have the general formula X-T, W-Y or X-(Pep)-Y, wherein X is a radiolabelled benzoyl or hydro...
4560795	α-Halomethyl derivatives of α-amino acids Novel halomethyl derivatives of α-amino acids of the following general structure: ##STR1## wherein Y is F 2 CH--, F 3 C--, Cl 2 CH--; Z is β-methylthioethyl, β-thioethyl, β-benzylthioethyl; S-(5'-desoxyadenosin-5'-yl)-S-methylthio...
4559340	Antihypertensive agents There are disclosed benzothiadiazinyl and quinazolinyl substituted carboxylalkyl dipeptides, wherein the benzothiodiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group. Compounds of this inventi...
4558065	Derivatives of tricyclic aminoacids, processes for their preparation, agents containing these compounds and their use, and new bicyclic aminoacids as intermediates and processes for their preparation The invention relates to new derivatives of tricyclic aminoacids, of the formula I ##STR1## in which n denotes 0 or 1, A denotes --CHCH-- or --CH 2 --CH 2 --, R denotes hydrogen, alkyl or aralkyl, R 1 denotes hydrogen, or alkyl, wh...
4555502	Aminoacyl-containing dipeptide derivatives useful as antihypertensives The invention relates to aminoacyl-containing dipeptide derivatives and related compounds which are useful angiotensin converting enzyme inhibitors and as antihypertensives.
4551272	Derivatives of dipeptide and their use in determining the activity of carboxypeptidase A Derivatives of dipeptide having the following general formula and their use as substrates for colorimetrically or spectrophotometrically measuring the activity of carboxypeptidase A: ##STR1## wherein X is OH in ortho or para position, or...
4549987	Aspartame synthesis A process for deformylation and separation of N-formyl-L- α-aspartyl-L-phenylalanine methyl ester from a mixture containing both α and β isomers thereof, which comprises admixing with said isomeric mixture hydrogen peroxide and an org...
4533657	Analgesic dipeptide amides and method of use and composition thereof A genus of dipeptide amides including as the preferred subgenus the dipeptide amides having the structural formula HTyrD-AlaNR 2 R 3 wherein R 2 is phenylalkyl or substituted-phenylalkyl and R 3 is hydrogen, alkyl, phenylalkyl, subst...
4533655	Analgesic dipeptide amides and method of use and compositions thereof A genus of dipeptide amides including as the preferred subgenus the dipeptide amides having the structural formula R 1 TyrR 2 D-AlaNHR 4 wherein R 1 and R 2 are each hydrogen or alkyl provided that at least one of them is other than...
4528282	Amide derivatives Amide derivatives of the formula: ##STR1## wherein either R 1 is aryl or heterocyclic and A 1 is a direct link, or R 1 is aryl or heterocyclic, or hydrogen, or halogeno, hydroxy, amino, guanidino, mercapto, carboxy, carbamoyl, or a su...
4518587	Dipeptides of L-5-hydroxytryptophan, processes for their preparation and drugs in which they are present The present invention relates to new dipeptides of L-5-hydroxytryptophan. They correspond to the general formula below: ##STR1## in which: X represents hydrogen or a lower acyl radical and Q represents a free or esterified aminoacid r...
4517180	Peptides, process for preparing the same and psychodepressant compositions containing the same This invention provides a peptide represented by the formula R--Tyr(SO 3 H)--Met--Gly--Trp--Met--Asp--W--NH 2 wherein R is HOOC--A--CO--Asp-- (wherein A is lower alkylene), pGlu--Asp--, HOOC--A--CO-- (wherein A is lower alkylene) or #...
4515715	L-Alanyl-D-isoglutamine adamantylamide The invention relates to L-Alanyl-D-isoglutamine adamantylamide of the formula ##STR1## wherein AD represents a residue of adamantane bound in the number 1 position. The described compound evidences an immunostimulatory and immunoadjuvan...
4512979	Dipeptides containing thialysine and related amino acids as antihypertensives The invention relates to dipeptide compounds containing thialysine and related amino acids which are useful as converting enzyme inhibitors and as antihypertensives.
4511504	Carboxyalkyl peptide derivatives This invention encompasses novel carboxyalkyl peptide derivatives which are collagenase inhibitors.
4507231	Process for the preparation of α-aspartyl phenylalanine methyl ester The present invention relates to a process for the preparation of α-aspartyl phenylalanine methyl ester by reacting phenylalanine methyl ester with the anhydride of N-formyl L-aspartic acid, process wherein the product from said reactio...
4505898	Derivatives of acetylsalicylic acid and substituted phenylacetic acids and compositions containing them Peptide derivatives of the formula A--NH--R 1 --CO] x [NH--R 2 --CO] y NH--R 3 --COOH in which A, R 1 , R 2 , R 3 , x, and y have the meaning specified in claim 1 and their physiologically acceptable salts and lower alkyl esters. ...
4505854	Optically active dipeptides and the use thereof as tissue dissolving and histolytic agent in human beings The invention relates to the new optically active dipeptide D-2-phenylglycyl-D-2-phenylglycine and its pharmacologically acceptable salts or acid addition salts and the use thereof as tissue dissolving and histolytic agent.
4503044	Antibiotic LL-D05139 β This disclosure describes a new antibacterial and anti-tumor agent designated LL-D05139 β, produced in a microbiological fermentation under controlled conditions using a new genus Glycomyces harbinensis gen. nov., sp. nov., and mutants ...
4503043	Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acid compounds and the pharmaceutically acceptable salts thereof are produced by acylating a suitably substituted octahydro-1H-isoindole with a suitably activated substi...
4500713	Therapeutic dipeptides (3S)-2-N-[(1S)-1-Ethoxycarbonyl-1-(2,3-dihydro-1H-inden-2-yl )-methyl]-L-ala nyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a antihypertensive agent.
4499082	α-Aminoboronic acid peptides Peptides comprising C-terminal α-aminoboronic acid residues are potent, reversible inhibitors of proteolytic enzymes.
4496540	Therapeutic compounds In one aspect, compounds capable of inhibiting an endopeptidase responsible for a degradation pathway of enkephalin and having the general formula A--B--NHOH wherein A is one of the aromatic group-containing amino acid residues L-trypt...
4487717	Process for recovering a dipeptide derivative A process for recovering a dipeptide derivative comprises admixing an aqueous mixture of a solid dipeptide ester derivative of the formula ##STR1## wherein R 1 is a lower alkyl group, R 2 is a side chain group of an amino acid, n i...

Matches 1 - 50 out of 300	1 2 3 4 5 6 >