Title:
【発明の名称】アレルギー性疾患の治療に有用な新規な置換4―(1H―ベンズイミダゾール―2―イル)〔1,4〕ジアゼパン類
Document Type and Number:
Japanese Patent JP2000500772
Kind Code:
A
Abstract:
The present invention relates to novel 4-(1H-benzimidazol-2-yl) [1,4]diazepane derivatives of formula (1) and stereoisomers thereof, and pharmaceutically acceptable salts thereof which are useful as histamine receptor antagonists and tachykinin receptor antagonist. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis.
Inventors:
Kane, Jiyoung M
Maynard, Yogi Day
Berkholder, Teimosh Pee
Bratton, Lari Day
Christopher Earle, Dalton
Sant'Eago, Braulio
Kudrats, Elizabeth M
Maynard, Yogi Day
Berkholder, Teimosh Pee
Bratton, Lari Day
Christopher Earle, Dalton
Sant'Eago, Braulio
Kudrats, Elizabeth M
Application Number:
JP52286396A
Publication Date:
January 25, 2000
Filing Date:
December 04, 1996
Export Citation:
Assignee:
Hoechst Marion Roussel Incorporated
International Classes:
A61K31/00; A61K31/55; A61K31/551; A61K31/5513; A61P1/00; A61P1/04; A61P11/00; A61P11/06; A61P29/00; A61P37/00; A61P37/08; A61P43/00; C07D401/14; C07D403/14; C07D405/14; C07D409/14; (IPC1-7): C07D403/14; A61P1/04; A61P11/06; A61P11/00; A61P29/00; A61P37/08; A61P37/00; A61P43/00; A61K31/5513; C07D401/14; C07D405/14; C07D409/14
Attorney, Agent or Firm:
Chika Takagi (1 person outside)
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