Title:
【発明の名称】ポドフイロトキシンからの4’―デメチルエピポドフイロトキシンの調製法
Document Type and Number:
Japanese Patent JP2000501726
Kind Code:
A
Abstract:
PCT No. PCT/FR96/02000 Sec. 371 Date Jun. 12, 1998 Sec. 102(e) Date Jun. 12, 1998 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/21713 PCT Pub. Date Jun. 19, 1997A method for synthesizing a 4'-demethylepipodophyllotoxin of formula (II) from a podophyllotoxin of formula (I) by treating it with a pair of reagents, i.e. a strong acid and an aliphatic, aromatic or functionalized sulphide, in the present of an organic or inorganic acid, or in the presence of water with or without a water-miscible organic solvent.
Inventors:
Amber, Thierry
Guminski, Eve
Guminski, Eve
Application Number:
JP52181397A
Publication Date:
February 15, 2000
Filing Date:
December 13, 1996
Export Citation:
Assignee:
Pierre, Fabre, Medicaman
International Classes:
C07D493/04; (IPC1-7): C07D493/04
Attorney, Agent or Firm:
Kazuo Sato (2 outside)