Title:
【発明の名称】α―ケトエステル及びα―ケトアミドのアシル化されたエノール誘導体
Document Type and Number:
Japanese Patent JP2000502073
Kind Code:
A
Abstract:
This invention relates to acylated enol derivatives of alpha -ketoesters and alpha -ketoamides. The compounds of this invention are either prodrugs of known elastase inhibitors or are elastase inhibitors in their own right and are useful in the treatment of various inflammatory diseases, including cystic fibrosis and emphysema.
Inventors:
Pete, Norton Pee
Burkhart, Joseph P
Mayday, Shujiate
Burkhart, Joseph P
Mayday, Shujiate
Application Number:
JP52126597A
Publication Date:
February 22, 2000
Filing Date:
November 04, 1996
Export Citation:
Assignee:
Hoechst Marion Roussel Incorporated
International Classes:
A61K31/00; A61K31/215; A61K31/216; A61K31/535; A61K31/5375; A61K38/00; A61P11/00; A61P29/00; A61P37/00; A61P37/02; C07D295/14; A61P43/00; C07D295/20; C07K5/00; C07K5/02; (IPC1-7): C07K5/00; A61P11/00; A61P29/00; A61P37/02; A61P43/00; A61K31/216; A61K31/5375; A61K38/00; C07D295/14; C07D295/20
Attorney, Agent or Firm:
Chika Takagi (1 person outside)