Title:
【発明の名称】メタロペプチダーゼ阻害活性を有するチオール誘導体
Document Type and Number:
Japanese Patent JP2000502687
Kind Code:
A
Abstract:
Compounds of formula (I), wherein R, R1, R2, and R3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
Inventors:
Francini, Terracini
Fantucci, mario
Norbrini, cabriel
Romagnano, Stefano
Sant'Angelo, Francesco
Semeraro, claudio
Fantucci, mario
Norbrini, cabriel
Romagnano, Stefano
Sant'Angelo, Francesco
Semeraro, claudio
Application Number:
JP52400197A
Publication Date:
March 07, 2000
Filing Date:
December 17, 1996
Export Citation:
Assignee:
Zambon Group S.P.A.
International Classes:
A61K31/00; A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/425; A61K31/426; A61K31/44; A61K31/4427; A61K31/4439; A61K31/495; A61K31/505; A61P9/00; A61P43/00; C07D213/55; C07D239/26; C07D241/12; C07D277/20; C07D277/30; C07D307/54; C07D333/24; C07D417/12; (IPC1-7): C07D213/55; A61P9/00; A61P43/00; A61K31/341; A61K31/381; A61K31/425; A61K31/426; A61K31/44; A61K31/4439; A61K31/495; A61K31/505; C07D239/26; C07D241/12; C07D277/30; C07D307/54; C07D333/24; C07D417/12
Attorney, Agent or Firm:
Miyuki Ariga (4 outside)
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