Title:
【発明の名称】造影剤
Document Type and Number:
Japanese Patent JP2000510838
Kind Code:
A
Abstract:
Compounds of formula (I) [M6Q8BnL6-n]x where M is Re or Rh; each Q is a bridging atom selected from O, S, Se and Te; B is a monovalent non-bridging atom or moiety; L is a PR3 group in which R is C1-6 alkyl or aryl, optionally substituted on the alkyl or aryl group by one or more water-solubilizing groups such as an amine or hydroxidy group, or the three R groups together form a C6-10 trivalent group which may also contain up to three nitrogen or oxygen atoms; n is an integer from 0 to 6; and x is an integer from -2 to +4, representing the overall charge of the cluster, which when non-zero is accompanied by one or more counter ions of equal and balancing charge, and contrast media, particularly X-ray contrast media, containing them.
Inventors:
Long, Jeffrey
Holm, Richard
Sanderson, William
You, Shibao
Zen, zippin
Dredge, Michael
Holm, Richard
Sanderson, William
You, Shibao
Zen, zippin
Dredge, Michael
Application Number:
JP54066497A
Publication Date:
August 22, 2000
Filing Date:
May 14, 1997
Export Citation:
Assignee:
Nycomd Salter, Inc.
International Classes:
A61K49/00; A61K49/04; C07F13/00; C07F15/00; (IPC1-7): C07F13/00; A61K49/00; C07F15/00
Attorney, Agent or Firm:
Hiroyuki Ikeuchi (3 outside)
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