Title:
【発明の名称】4,6―ジヒドロキシピリミジンの製造方法
Document Type and Number:
Japanese Patent JP2000510864
Kind Code:
A
Abstract:
A process for preparing 4,6-dihydroxypyrimidine comprising the steps: a) contacting formamide, an alkoxide of formula ROM and a malonate of formula CH2(CO2R)2 in a solvent of formula ROH; b) adding water to the product of step (a); c) removing substantially all of the solvent of formula ROH from the product of step (b); and d) acidifying the product of step (c) wherein R is C1-4 alkyl and M is an alkali metal.
More Like This:
Inventors:
Jones, Raymond Vincent Haven
Ritchie, David John
Cronby, Barry Stuart
Ritchie, David John
Cronby, Barry Stuart
Application Number:
JP54175697A
Publication Date:
August 22, 2000
Filing Date:
April 24, 1997
Export Citation:
Assignee:
Zeneca Limited
International Classes:
C07D239/54; (IPC1-7): C07D239/54
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)