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Title:
【発明の名称】神経精神、免疫又は内分泌障害を治療するための7α置換ステロイドの使用
Document Type and Number:
Japanese Patent JP2000511404
Kind Code:
A
Abstract:
Use is provided for a 7alpha-hydroxy or 7-oxo substituted 3beta-hydroxy-steroid possessing the carbon skeleton of cholesterol, androsterone, pregnenolone or estradiol, or an analogue thereof substituted independently at one or both of the 7- and 3-positions with an ester or ether group, in the manufacture of a pharmaceutical composition for the therapy of neuropsychiatric, immune and/or endocrine disorders or for inducing cognitive enhancement. Uses for Cyp7b enzymes in producing such steroids is also provided together with various novel steroids and test kits and methods for diagnosing the disorders.

Inventors:
Raise, lithyard
Rose, kennys andrew
Settle, Jimonathan Robert
Vest, loose
Yau, The Joyce Lai Wah
Letsky, Kyaro Line Matsukenji
Application Number:
JP53596197A
Publication Date:
September 05, 2000
Filing Date:
April 04, 1997
Export Citation:
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Assignee:
Be Tay G. International Limited
International Classes:
C12N15/09; A61K31/00; A61K31/565; A61K31/57; A61P3/00; A61P3/06; A61P3/10; A61P5/38; A61P19/00; A61P19/10; A61P21/00; A61P21/04; A61P25/24; A61P25/28; A61P37/00; A61P37/04; C07J1/00; C12N9/02; C12P21/08; C12P33/00; C12P33/06; A61K38/00; (IPC1-7): C12N15/09; A61P3/00; A61P3/10; A61P3/06; A61P5/38; A61P19/10; A61P21/04; A61P25/28; A61P25/24; A61P37/04; A61K31/565; C07J1/00; C12N9/02; C12P21/08; C12P33/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)