Title:
【発明の名称】ホスホロチオエートオリゴヌクレオチド合成法
Document Type and Number:
Japanese Patent JP2000511933
Kind Code:
A
Abstract:
This invention presents novel methods for synthesizing phosphorothioate oligonucleotides, using support-bound phosphoramidites. Novel intermediates useful in the methods are also provided.
Inventors:
Cole, Douglas El
Ravi Kumar, Vathlinga
Ravi Kumar, Vathlinga
Application Number:
JP53013798A
Publication Date:
September 12, 2000
Filing Date:
December 12, 1997
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C07H21/00; (IPC1-7): C07H21/00
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)