Title:
【発明の名称】集合欠損ヘルペスウイルスワクチン
Document Type and Number:
Japanese Patent JP2000516597
Kind Code:
A
Abstract:
A vaccine is described which comprises an assembly-deficient herpesvirus. The mutant herpesvirus is capable of infecting and undergoing DNA replication in the cells of a susceptible mammal, but is defective in capsid assembly and formation of mature virion particles. The assembly-deficient herpesvirus is avirulent and capable of generating a protective immune response in a vaccinated mammal.
Inventors:
Hippenmeyer, Paul, Jay.
Rankin, Anne, M.
Sea otter, barn, sting.
Rankin, Anne, M.
Sea otter, barn, sting.
Application Number:
JP50917698A
Publication Date:
December 12, 2000
Filing Date:
July 25, 1997
Export Citation:
Assignee:
G.D.Searle & Company
International Classes:
A61K38/46; A61K39/00; A61K39/245; A61K48/00; A61P31/22; C12N5/10; C12N7/00; C12N9/50; C12N15/52; C12N15/09; C12R1/92; (IPC1-7): A61K39/245; A61K38/46; A61K39/00; A61K48/00; A61P31/22; C12N5/10; C12N7/00; C12N15/09
Attorney, Agent or Firm:
Akira Asamura (3 outside)