Title:
【発明の名称】複素環式メタロプロテアーゼ阻害剤
Document Type and Number:
Japanese Patent JP2000516953
Kind Code:
A
Abstract:
The invention provides compounds of formulaas described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptacle salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
Inventors:
Pickle, Stanislaw.
McDow-Dunham, Kelly, Lynn.
De, Wiswanus.
Taiwo, Jeetunde, Orabishi.
Almstead, Neil, Gregory.
Bradley, Rinma, Sandler.
Natures, Michael, George.
Capsu, Thomas, Lee.
McDow-Dunham, Kelly, Lynn.
De, Wiswanus.
Taiwo, Jeetunde, Orabishi.
Almstead, Neil, Gregory.
Bradley, Rinma, Sandler.
Natures, Michael, George.
Capsu, Thomas, Lee.
Application Number:
JP51171398A
Publication Date:
December 19, 2000
Filing Date:
August 22, 1997
Export Citation:
Assignee:
THE PROCTER & GAMBLE COMPANY
International Classes:
A61K31/505; A61K31/551; A61K31/554; A61P1/02; A61P11/06; A61P17/00; A61P19/00; A61P19/02; A61P27/02; A61P43/00; C07D239/06; C07D243/08; C07D281/06; C07D403/12; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D487/06; (IPC1-7): C07D239/06; A61K31/505; A61K31/551; A61K31/554; A61P1/02; A61P11/06; A61P17/00; A61P19/02; A61P27/02; A61P43/00; C07D243/08; C07D281/06; C07D403/12; C07D409/14; C07D413/12
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)