Title:
【発明の名称】骨形態形成蛋白―16(BMP―16)組成物
Document Type and Number:
Japanese Patent JP2001500737
Kind Code:
A
Abstract:
Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
Inventors:
Celeste, Anthony Jay
Murray, Beth El
Murray, Beth El
Application Number:
JP51465198A
Publication Date:
January 23, 2001
Filing Date:
July 09, 1997
Export Citation:
Assignee:
Genetics Institute, Inc.
International Classes:
C12N15/09; A61K38/00; A61P1/02; A61P19/00; A61P19/02; A61P19/10; A61P43/00; C07K14/47; C07K14/495; C07K14/51; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12P21/02; (IPC1-7): C12N15/09; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)