Title:
【発明の名称】非―ペプチドボンベシン受容体アンタゴニスト
Document Type and Number:
Japanese Patent JP2001500850
Kind Code:
A
Abstract:
The compounds of the instant invention are novel compounds of Formula Ior a pharmaceutically acceptable salt thereof wherein Ar is phenyl or pyridyl unsubstituted or substituted. Ar1 can be independently selected from Ar and can also include pyridyl-N-oxide, indolyl, imidazole, and pyridyl; R3 can be independently selected from Ar or is hydrogen, hydroxy, NMe2, N-methyl-pyrrole, imidazole, tetrazole, thiazole (a), (b), (c), or (d), wherein Ar2 is phenyl or pyridyl. The instant compounds antagonize the bombesin receptors in mammals and are therefore effective in treating and/or preventing depression, psychoses, seasonal affective disorders, cancer, feeding disorders, gastrointestinal disorders, inflammatory bowel disease, sleep disorders, and memory impairment.
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Inventors:
Howell, David Christopher
Martin clive, pritchard
Martin clive, pritchard
Application Number:
JP51077998A
Publication Date:
January 23, 2001
Filing Date:
August 06, 1997
Export Citation:
Assignee:
Warner-Lambert Company
International Classes:
C07D213/12; A61K31/405; A61K31/4178; A61K31/427; A61K31/4402; A61K31/4439; A61K31/454; A61P1/00; A61P25/00; A61P35/00; C07D209/20; C07D213/40; C07D213/56; C07D213/89; C07D401/12; C07D403/12; C07D405/12; C07D417/12; (IPC1-7): C07D209/20; A61K31/405; A61K31/4178; A61K31/427; A61K31/4402; A61K31/4439; A61K31/454; A61P1/00; A61P25/00; A61P35/00; C07D213/12; C07D213/40; C07D213/89; C07D401/12; C07D403/12; C07D417/12
Attorney, Agent or Firm:
Chika Takagi (1 person outside)