Title:
【発明の名称】免疫調節作用を有する調合物
Document Type and Number:
Japanese Patent JP2001501921
Kind Code:
A
Abstract:
Pharmaceutical compositions especially for internal application which create lyotropic liquid crystals when in contact with aqueous phase. The pharmaceutical compositions consist of:A hydrophobic active ingredient with immunomodulatory effect from a group of N-methylated cyclic undecapeptides or macrolide antibiotics, in quantity 1-35 weight % in a carrier medium containingB at least one absorption promoter allowing for contact of the drug with a biological membrane or passing of the drug through in quantity 1-40 weight %,C nonlipidic vehicle containing at lest one of the below mentioned substances:C1 surfactant or mixed surfactant with HLB>9, in quantity 1-80 weight %C2 lipophilic solvent from group of higher fatty alcohols in quantity 1-30 weight %C3 at least one cosurfactant in quantity 1-50 weight %,while a ratio among the individual components of the product is A:B:C=1:0.5-4:5-8.
Inventors:
Stuclik, Milan
Yegorov, Alexander
Hussec, Ares
Marta, Vladimir
Stuclik, Joseph
Andrisek, Thomas
Yegorov, Alexander
Hussec, Ares
Marta, Vladimir
Stuclik, Joseph
Andrisek, Thomas
Application Number:
JP51337898A
Publication Date:
February 13, 2001
Filing Date:
September 12, 1997
Export Citation:
Assignee:
Galena Akziover Spoletinosto
International Classes:
A61K9/00; A61K9/10; A61K9/127; A61K31/4353; A61K31/436; A61K38/00; A61K38/13; A61K47/00; A61K47/08; A61P31/00; (IPC1-7): A61K38/00; A61K9/127; A61K31/4353; A61K47/00
Attorney, Agent or Firm:
Hironobu Onda
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